Clinical trials: Tendon Injury
Tendinopathy
Study of Efficacy, Safety and Tolerability of AIN457 in Patients With Active Overuse Tendinopathy
This was a randomized, double-blind, placebo-controlled, multi-center, Phase II study of s.c. secukinumab 300 mg in 98 randomized patients with overuse rotator-cuff tendinopathy without systemic inflammatory disease.
- Trial name
- NCT03344640
- Testing
- secukinumab
- Where
- 12 sites in United States, Czechia and 3 more
- Volunteers
- 96 people
- Sponsor
- Novartis Pharmaceuticals
Lateral Epicondylitis
5% and 15% Dextrose Prolotherapy Efficacy in Lateral Epicondylitis
In the treatment of lateral epicondylitis, 5% dextrose prolotherapy is aimed to be more reliable than 15% prolotherapy in terms of side effects and to show that it is similar in terms of efficacy in treatment.
- Trial name
- NCT05066451
- Testing
- %5 dextrose prolotherapy, %15 dextrose prolotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Lateral Epicondylitis, Extracorporeal Shockwave Therapy
Polydeoxyribonucleotide for Elbow Lateral Epicondylitis
The goal of this clinical trial is to investigate the synergistic effect of polydeoxyribonucleotide (PDRN) on extensor muscle strengthening exercise (EMSE) combined with extracorporeal shockwave therapy (ESWT) for treating…
- Conditions
- Lateral Epicondylitis, Extracorporeal Shockwave Therapy, Muscle Strengthening
- Trial name
- NCT06753630
- Testing
- Extensor Muscle Strengthening Exercise, Extracorporeal Shockwave Therapy, Polydeoxyribonucleotide Injection
- Where
- South Korea
- Volunteers
- 48 people
- Sponsor
- Chuncheon Sacred Heart Hospital
Rotator Cuff Tear
Functional Outcomes Following Shoulder Surgery: A Prospective Database
The purpose of this prospective database is to investigate the long-term functional status of patients who have undergone various types of rotator cuff repair surgery.
- Trial name
- NCT00253864
- Testing
- Single row, Double row
- Where
- Canada
- Volunteers
- 90 people
- Sponsor
- Ottawa Hospital Research Institute
Lateral Epicondylitis
Multimodal Rehabilitation Approach in Patients of Lateral Epicondylitis
Literature is scarce for high quality evidence regarding multimodal rehabilitation in lateral epicondylitis. By making comparisons with the conventional treatment of patients with lateral epicondylitis, the current study aims to…
- Trial name
- NCT06686732
- Testing
- Multimodal physiotherapy, Conventional physiotherapy
- Where
- 3 sites in Pakistan
- Volunteers
- 40 people
- Sponsor
- Riphah International University
Shoulder Instability, Frozen Shoulder
Virtual Reality Rehabilitation for Shoulder Pathologies
Most rehabilitation protocols require patients to train the affected limbs with high regularity, following repetitive cycles of exercises, in order to recover mobility and strength.
- Conditions
- Shoulder Instability, Frozen Shoulder, Rotator Cuff Tears
- Trial name
- NCT06963983
- Testing
- Rehabilitation using virtual reality
- Where
- Switzerland
- Volunteers
- 15 people
- Sponsor
- La Tour Hospital
Rotator Cuff Injuries
Clinical Study On Extracorporeal Shock Wave Therapy For Rotator Cuff Injuries
This clinical trial aims to learn about the effect of extracorporeal shock wave therapy on rotator cuff injuries. The main question it aims to answer is the efficacy of extracorporeal shock wave therapy on the improvement of…
- Trial name
- NCT06329154
- Testing
- Extracorporeal shock wave therapy, conventional rehabilitation therapy
- Where
- China
- Volunteers
- 58 people
- Sponsor
- Yong Liu, MD
Anterior Cruciate Ligament Injury, Anterior Cruciate Ligament Rupture
Arthroscopic ACL Reconstruction: Hamstring Versus Quadriceps
The use of hamstrings and quadriceps autografts as an alternative option for reconstruction of the anterior cruciate ligament has good clinical results: however, both techniques have not been compared among them, which is why…
- Trial name
- NCT04137250
- Testing
- Hamstring, Quadriceps tendon
- Where
- Mexico
- Volunteers
- 28 people
- Sponsor
- Universidad Autonoma de Nuevo Leon
Rotator Cuff Tear
Types of Fixation in Arthroscopic Rotator Cuff Repair
The study will identify if there is a difference of quality of life after surgery between two techniques used in surgery. The two different techniques are either the Single Row Fixation or the Double Row Fixation.
- Trial name
- NCT00508183
- Testing
- single row, double row fixation
- Where
- Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Rotator Cuff Tear, Rotator Cuff Tendinitis
Autologous Adult Adipose-Derived Regenerative Cell Injection Into Chronic Partial-Thickness Rotator Cuff Tears
The purpose of this investigation is to evaluate the safety and superior effectiveness in functional improvement in patients with partial-thickness rotator cuff tears (PTRCTs) after the administration of a single injection of…
- Trial name
- NCT03752827
- Testing
- Adipose Derived Regenerative Cells, Corticosteroid
- Where
- 14 sites in United States
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- InGeneron, Inc.
Rotator Cuff Tear, Shoulder Impingement Syndrome
Arthroscopic Rotator Cuff Repair of Full Thickness Tears With and Without Arthroscopic Acromioplasty
Surgical repair of full thickness tears of the rotator cuff is a controversial issue, with several procedures currently being used to treat the tear.
- Trial name
- NCT00290888
- Testing
- Acromioplasty
- Where
- Canada
- Volunteers
- 86 people
- Sponsor
- Panam Clinic
Lateral Epicondylitis
Lateral Epicondylitis Treatment High Intensive Laser Therapy and Extracorporeal Shock Wave Therapy
Objectives: This study aims to evaluate and compare the short-term efficacy of high-intensity laser therapy (HILT) and extra corporeal shock wave therapy(ESWT) on pain, sensitivity, handgrip strength, and functions in the…
- Trial name
- NCT06301152
- Testing
- high intensive laser, extracorporeal shock wave therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Rotator Cuff Tears, Central Sensitisation
Effect of Pregabalin on Shoulder Pain in Patients With Central Sensitization After Arthroscopic Rotator Cuff Repair
This study aims to investigate the effects of Pregabalin intake on shoulder pain management in patients with central sensitization undergoing arthroscopic rotator cuff repair.
- Conditions
- Rotator Cuff Tears, Central Sensitisation, Neuropathic Pain
- Trial name
- NCT06367998
- Testing
- Pregabalin
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- The Catholic University of Korea
Rotator Cuff Tear
A Selective COX-2 Inhibitor Provides Pain Control But Hinders Healing Following Arthroscopic Rotator Cuff Repair
Selective cyclooxygenase (COX)-2 inhibitors are commonly used analgesics that provide similar analgesia but reduced adverse effects compared to other analgesics.
- Trial name
- NCT02850211
- Testing
- Celecoxib, Ibuprofen, Tramadol
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Rotator Cuff Tears
Measuring Opioid Use After Rotator Cuff Repair: Comparing the Effects of Standard vs. Extended-release Nerve Blocks
The investigators aim to determine if a longer acting nerve block, which is a local anesthetic, can help reduce opioid use after surgery in patients that are getting rotator cuff repair surgery.
- Trial name
- NCT05482113
- Testing
- Liposomal bupivacaine, Bupivacaine Hcl 0.25% Inj
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Carilion Clinic
Rotator Cuff Tear
Supra-spinatus Rehabilitation Program Comparison
Through a prospective randomized study the aims of this study is to analyze the impact of 3 types of rehabilitation protocols on the Optimization of the post-operative clinical and anatomic healing of the rotator cuff.
- Trial name
- NCT01467336
- Testing
- Arthroscopic rotator cuff repair
- Where
- 4 sites in France
- Volunteers
- 229 people
- Sponsor
- University Hospital, Strasbourg, France
Posterior Tibial Tendon Dysfunction
Bracing and Strengthening for Posterior Tibial Tendon Dysfunction
Posterior tibial tendon dysfunction (PTTD) is a problem with the tendon connecting one of the lower leg muscles to the foot bone. PTTD can cause pain, swelling, and a flattened foot and may require surgery if left untreated.
- Trial name
- NCT00756457
- Testing
- Bracing, Strengthening exercises, Stretching exercises
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Ithaca College
Rotator Cuff Tears, Postoperative Pain Management
Pain Education After Rotator Cuff Surgery
Study Title: The Effect of Pain Neuroscience Education Combined with Conventional Rehabilitation on Pain Management and Functional Outcomes in Patients Undergoing Mini-Open Rotator Cuff Repair Purpose: This study aims to…
- Conditions
- Rotator Cuff Tears, Postoperative Pain Management, Shoulder Dysfunction, Kinesiophobia (Fear of Movement)
- Trial name
- PNE-RCS (NCT06886932)
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Elif Dilara Durmaz
Tendinopathy, Lasers
Effectiveness of Laser Therapy on Proximal Hamstring Tendinopathy
Proximal hamstring tendinopathy (PHT) is tendinopathy of the semimembranosus and/or biceps femoris/semitendinosus complex. Previous studies have shown the efficacy of laser therapy in the treatment of tendinopathy.
- Trial name
- NCT05100394
- Testing
- Laser Therapy, Ultrasound + Moist Heat pack + Exercises
- Where
- Saudi Arabia
- Volunteers
- 36 people
- Sponsor
- King Saud University
Tendinopathy
The Acute Effects of an Isometric Loading Intervention on Lower Extremity Landing Biomechanics in Individuals With Patellar Tendinopathy
The purpose of this study is to determine differences in lower extremity landing biomechanics and real-world physical activity between individuals with patellar tendinopathy compared to individuals without patellar…
- Trial name
- NCT03262181
- Testing
- Isometric Exercise
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
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