Clinical trials: Terminal Cancer
Terminal Cancer, Hospice
Exploring Indications and Practices of Administering Artificial Hydration to Terminal Cancer Patients in Taiwan
Background: The issue of artificial hydration for terminal cancer patients is a classic ethical dilemma in palliative care. It is a common practice especially when patients are incapable of oral intake; however, there is a lack…
- Conditions
- Terminal Cancer, Hospice, Palliative Medicine
- Trial name
- NCT06329856
- Testing
- Administering of artificial hydration
- Where
- Taiwan
- Volunteers
- 391 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Cancer, Malignancies Multiple
Remote Vital Sign Monitoring in Palliative Care Patients Using a Wearable ECG Monitor
The goal of this study is the assess the use of remote monitoring of vital signs using commercially available medical devices in patients with advanced cancer admitted to a hospice inpatient unit for end-of-life care.
- Conditions
- Cancer, Malignancies Multiple, Terminal Care, Hospice
- Trial name
- VITAL-PC (NCT07512505)
- Where
- Ireland
- Volunteers
- 120 people
- Sponsor
- Our Lady's Hospice and Care Services
Neoplasms (Cancer / Tumors), Palliative Care
Nurse-Led Culturally Adapted Palliative and End-of-Life Training for Oncology Nurses in Oman
This study evaluated a nurse-led, culturally adapted training program in palliative and end-of-life care (N-PELTP) for oncology nurses in Oman.
- Conditions
- Neoplasms (Cancer / Tumors), Palliative Care, Terminal Care
- Trial name
- N-PELTP (NCT07460570)
- Testing
- N-PELTP Palliative and End-of-Life Training Program
- Where
- 2 sites in Oman
- Volunteers
- 189 people, healthy volunteers welcome
- Sponsor
- Sultan Qaboos University
Hospice, Psilocybin
Pilot Study of Psilocybin-Assisted Therapy for Demoralization in Patients Receiving Hospice Care
The overall objective of this study is to develop and pilot test a novel regimen of psilocybin-assisted psychotherapy for demoralization in patients receiving hospice care.
- Conditions
- Hospice, Psilocybin, Demoralization, Terminal Illness
- Trial name
- PATH (NCT04950608)
- Testing
- Psilocybin, Psychotherapy
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Yvan Beaussant, MD, MSci
Palliative Patients, Terminal Malignant Tumors
Effect of Breathing Exercises on Pain, Dyspnea, and Function in Terminal-Stage Cancer Patients
This study aims to evaluate the effects of supervised breathing exercises on pain, dyspnea, and functionality in terminal-stage cancer patients receiving palliative care.
- Conditions
- Palliative Patients, Terminal Malignant Tumors, Breathing Techniques
- Trial name
- NCT07164352
- Testing
- Breathing Exercises, Informational Brochure
- Where
- Turkey (Türkiye)
- Volunteers
- 58 people
- Sponsor
- Atlas University
Terminal Illness, Terminal Cancer
Differences in Acceptability of Music Therapy Sessions Played Live Compared to a Recording Thereof
The present study seeks to assess differences in feasibility and acceptability of music therapy played live and listening to a recording thereof at the palliative care ward of the University Hospital Zurich.
- Trial name
- NCT06108375
- Testing
- music therapy, recording
- Where
- Switzerland
- Volunteers
- 25 people
- Sponsor
- University of Zurich
Terminal Illness, Terminal Cancer
DigiPall; a Trial of Digital Patient Reported Outcome and Biomarker Monitoring in Palliative Care
The aim of this study is to test if a system consisting of a wearable device measuring heartbeats and steps, together with daily communication with a chatbot on the smartphone asking the patients about their symptoms and giving…
- Trial name
- NCT06615349
- Testing
- DigiPall
- Where
- Switzerland
- Volunteers
- 382 people
- Sponsor
- David Blum
Terminal Cancer, Metastatic Cancer
Advanced Planning for Online Accounts and Data
The proposed research consists of engagements with terminal cancer patients and their friends and family as they engage in end-of-life planning.
- Trial name
- NCT05222308
- Testing
- Post-Mortem Plan
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Advanced Cancer, Terminal Malignant Tumors
Nurses' Competence and Role in Survival Prediction and Prognostic Communication
[Background] Nurses' roles in survival prediction and prognostic communication have historically been limited due to role delineation, lack of formal training, and cultural norms.
- Conditions
- Advanced Cancer, Terminal Malignant Tumors, Hospices
- Trial name
- NCT06962553
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Terminal Cancer
Towards Cancer Patient Empowerment for Optimal Use of Antithrombotic Therapy at the End of Life
Despite the fact that antithrombotic therapy (ATT) has little or even negative effects on the well-being of cancer patients during their last year of life, stopping ATT is rare in clinical practice.
- Trial name
- SERENITY (NCT05706740)
- Testing
- Physician survey on antithrombotic medication during end-of-life care in cancer patients
- Where
- 12 sites in Denmark, France and 6 more
- Volunteers
- 467 people, healthy volunteers welcome
- Sponsor
- Johannes Gutenberg University Mainz
to Investigate the Level of Fatigue Among Terminal Cancer Patients Receiving Home-based Hospice Care
Cancer-related Fatigue Among Patients Receiving Home-based Palliative Care
Cancer-related fatigue, which significantly impacts the quality of life, is prevalent among patients with terminal cancer. The experiences of fatigue, its associated needs, and the strategies for managing it are closely linked to…
- Trial name
- NCT06498193
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- National Taipei University of Nursing and Health Sciences
Metastatic Pancreatic Cancer, Terminal Cancer
Vitamin C to Quality of Life in Patients With Terminal Stage Pancreatic Cancer
The purpose of this study is to evaluate the efficacy of vitamin C in improving the quality of life for metastatic pancreatic cancer patients who are resistant to chemotherapy.
- Trial name
- PTCA199-4 (NCT06018896)
- Testing
- Ascorbate
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Fudan University
Cancer Terminal
Palliative Care for Elderly Outpatients
Our long-term goal is to improve spiritual care outcomes for elderly patients with cancer. The study team will use a spiritual intervention, Dignity Therapy (DT), to help these patients maintain pride, find spiritual comfort…
- Trial name
- NCT03209440
- Testing
- Dignity Therapy - Nurse Led, Usual care, Dignity Therapy - Chaplain Led
- Where
- United States
- Volunteers
- 579 people
- Sponsor
- University of Florida
Neoplasms, Terminal Illness
Parenteral Nutrition Therapy in Patients With Incurable Cancer
Parenteral nutrition (PN) treatment in patients with incurable cancer is understudied and the level of evidence for clinical meaningful effects is weak.
- Trial name
- PATNIC (NCT04456647)
- Testing
- Parenteral nutrition
- Where
- 4 sites in Norway
- Volunteers
- 507 people
- Sponsor
- Norwegian University of Science and Technology
Terminal Cancer, End Stage Cancer
Using Wearable Device to Improve Quality of Palliative Care
This study is going to use wearable devices and smartphones to collect physical data from terminal patients and build a survival predicting model for terminal patients with machine learning.
- Trial name
- NCT05054907
- Where
- 2 sites in Taiwan
- Volunteers
- 75 people
- Sponsor
- National Taiwan University Hospital
Cancer, End Stage Cancer
Information Needs Around Parenteral nUTrition in Cancer
This study will explore the information needs of patient's with advanced cancer, and their carers, when making a decision to commence or discontinue parenteral nutrition.
- Conditions
- Cancer, End Stage Cancer, Terminal Cancer, Neoplasms
- Trial name
- INPUT (NCT04495530)
- Testing
- Non-interventional study
- Where
- 4 sites in United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Royal Marsden NHS Foundation Trust
Palliative Care, Diabetes Mellitus, Type 2
GLYPALCARE STUDY - Multicenter, Randomized Study for Evaluating Continuous Glucose Monitoring (CGM) by Using FreeStyle Libre 2 (FSL2) for Preventing Hyperglycemia/Hypoglycemia Crisis in Advanced Oncological Patients.
Cancer patients with known or newly diagnosed (i.e. iatrogenic) Diabetes Mellitus (DM) in Palliative/Supportive Care will be enrolled. Patients will be randomly assigned to one of two groups.
- Conditions
- Palliative Care, Diabetes Mellitus, Type 2, Diabetes Mellitus, Type 1, Diabetes
- Trial name
- NCT04942756
- Testing
- Continuous Glucose Monitoring, Standard Care
- Where
- 6 sites in Israel, Italy and 1 more
- Volunteers
- 118 people
- Sponsor
- Antea Foundation
Terminal Malignant Tumors
A Study to Evaluate the Tolerance and Pharmacokinetics of TQB2858 Injection in Subjects With Terminal Malignant Tumors
This study is a phase I study to evaluate the safety and tolerability of TQB2858 injection in patients with advanced malignancy.
- Trial name
- NCT04805060
- Testing
- TQB2858 injection
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
ALS, Autism Spectrum Disorder
Pharmacokinetic (PK) and Pharmacodynamics (PD) Study of Ilera Specific Products
This is an observational study of medical marijuana manufactured and dispensed by Ilera and given as standard treatment for a variety of approved serious medical conditions as defined by individual state law.
- Conditions
- ALS, Autism Spectrum Disorder, Cancer, Spasticity, Muscle
- Trial name
- Ilera (NCT03886753)
- Testing
- Registry, PK microsampling of blood
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Children's Hospital of Philadelphia
Narrative Medicine, Chronic Disease
Impact of Early Implementation of Narrative Medicine Techniques on Patient Centered Attitudes of Medical Students
A qualitative study assessing the impact of early narrative medicine practice on Medical Honors Program (MHP) students' attitudes regarding patient-centered interactions, through interviewing patients with chronic or…
- Conditions
- Narrative Medicine, Chronic Disease, Terminal Illness, Cancer
- Trial name
- NCT03041571
- Testing
- Patient Provider Orientation Scale, Interview performed by MHP student
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Florida