Clinical trials: Test
Mild Cognitive Impairment, Mild Cognitive Impairment (MCI)
Community-based Multi-domain Intervention to Detect and Delay Cognitive Decline in Community-dwelling Older Adults: A Pilot Study
The incidence of cognitive impairment and its burden are increasing with a rapidly ageing population. In Singapore, the prevalence of dementia among older adults aged 60 and above is approximately 10%, which will translate to…
- Trial name
- NCT07099040
- Testing
- Social support, Health coaching, Physical Activity
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Singapore General Hospital
Healthy Subjects
A Study Evaluating Bioequivalence of a Fixed Dose Combination Versus Individual Tablets of Bempedoic Acid, Ezetimibe, and Atorvastatin
Monotherapies for lowering LDL-C often do not achieve target lipid levels because they act on a single pathway, which may be insufficient in patients with high cardiovascular risk or complex lipid profiles.
- Trial name
- NCT07235189
- Testing
- Bempedoic acid, Ezetimibe, Atorvastatin
- Where
- Portugal
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Daiichi Sankyo
Drug Allergy
Teicoplanin Allergy Testing Using Autologous Serum (TATAS)
Allergy testing for Teicoplanin is much more unreliable than for other similar drugs. This means that we run the risk of missing serious Teicoplanin allergy, and these patients will be given another dose in future, not knowing…
- Trial name
- TATAS (NCT06803758)
- Testing
- Teicoplanin Allergy Testing using autologous serum
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Core Muscle Endurance
Efficacy Testing of Les Mills Pilates
Objectives: Determine the effect of an 8-week intervention of the new group fitness program Les Mills Pilates on balance, core stability, abdominal, back, and hip muscle endurance, flexibility, and mood.
- Trial name
- NCT06409858
- Testing
- Pilates
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of the Fraser Valley
Vaccination Hesitancy, Human Papillomavirus Vaccination
Testing the Persuasiveness of Pro-inoculation Arguments
The investigators will recruit a national sample of parents of 7-10-year-olds to complete an argument strength ranking for either a simple forwarding message or between 3 and 6 randomly selected arguments from an overall set of…
- Conditions
- Vaccination Hesitancy, Human Papillomavirus Vaccination, Vaccine Refusal
- Trial name
- NCT05804825
- Testing
- Argument inoculation messages, Simple forewarning message
- Where
- United States
- Volunteers
- 523 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Breast Cancer Female, Breast Cancer
Oncoliq: Early Breast Cancer Detection Based on Liquid Biopsies and microRNAs
Oncoliq is a novel early breast cancer detection test based on liquid biopsies and microRNAs. This innovative test aims to improve the accuracy of cancer detection, thereby reducing patient mortality and healthcare costs.
- Conditions
- Breast Cancer Female, Breast Cancer, Breast Carcinoma
- Trial name
- NCT06439940
- Testing
- Blood sample extraction
- Where
- Argentina
- Volunteers
- 364 people, healthy volunteers welcome
- Sponsor
- Oncoliq US Inc
Hyperpigmentation
An 18-week Study to Evaluate a Test Product With a Marketed Prescription Product
The purpose of this study is to assess the efficacy (ability to produce a desired or intended result) of a topical product (applied to the skin) to improve skin lightness, skin condition and appearance (hyperpigmentation [dark…
- Trial name
- NCT07136766
- Testing
- Facial Toner
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Good Molecules, LLC
Sunscreening Agents
18794 - Human Photo Toxicity Test
To determine the phototoxic potential of a topically applied article in human subjects.
- Trial name
- NCT02751372
- Testing
- BAY 987517, Untreated Skin
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Bayer
Stress, Psychological Stress
Examine the Effects of Meditation on Daily Psychological Stress Responses in Woman With a History of Child Adversity
The aim of the Everyday Moments of Mindfulness (EMMI) study is to test whether brief mindfulness-based practices will improve daily psychological stress responses in women (age 30-60) who report a history of early life adversity.
- Conditions
- Stress, Psychological Stress, Child Maltreatment, Depressive Symptoms
- Trial name
- EMMI (NCT04606199)
- Testing
- Mindfulness-based intervention, up to 5 minutes 0-3 times/day
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Memory Disorders, Neurocognitive Disorders
Creation of an Ecological Tool Assessing Episodic Memory in Geriatrics
In this study the participants can be recruited via scheduled consultation and external institutions (associations, senior club..).
- Trial name
- ECOTESTGER (NCT05668598)
- Testing
- ecological MAI test
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier de Lens
Healthy Subjects
Evaluating Bioequivalence of a Fixed Dose Combination Versus Individual Tablets of Bempedoic Acid / Ezetimibe, and Atorvastatin
Monotherapies for lowering LDL-C often do not achieve target lipid levels because they act on a single pathway, which may be insufficient in patients with high cardiovascular risk or complex lipid profiles.
- Trial name
- NCT07268625
- Testing
- Bempedoic acid, Ezetimibe, Atorvastatin
- Where
- Portugal
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Daiichi Sankyo
Sexual Violence
Preventing Sexual Violence Among Middle School Boys With a Strengths-Based Curriculum
This research will examine if participation in a strengths-based curriculum, the Brothers as Allies program adapted from the Council for Boys and Young Men, reduces risk for future sexual violence perpetration among middle…
- Trial name
- NCT03392597
- Testing
- Brothers as Allies, Programming-as-Usual
- Where
- United States
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- New York State Department of Health
Asphyxia Neonatorum
Biomarkers And Neurological Outcome in Neonates (BANON)
Validation of biomarkers in a human population for their ability to diagnose the severity of neonatal asphyxia. These biomarkers linked to asphyxia have been identified in animal studies and a preliminary human study.
- Trial name
- NCT03357250
- Where
- 11 sites in Germany
- Volunteers
- 553 people, healthy volunteers welcome
- Sponsor
- Life Science Inkubator
Breast Abnormality
Circulating Tumor Cells (CTCs): A Potential Screening Test for Clinically Undetectable Breast Carcinoma
With an estimated > 2 million women with undetected breast cancer in the United States, the need for improved early detection is imperative.
- Trial name
- NCT01322750
- Where
- United States
- Volunteers
- 3,125 people, healthy volunteers welcome
- Sponsor
- Walter Reed Army Medical Center
Diagnostic Test, Routine, Coronavirus
COVID-19 Testing Pilot Study
The purpose of this study is to determine the reliability of a low-cost rapid diagnostic test for COVID-19. The method of the testing procedure uses electrochemistry to detect COVID-19 spike proteins within human samples.
- Conditions
- Diagnostic Test, Routine, Coronavirus, Diagnoses Disease, Rapid Coronavirus Test
- Trial name
- NCT04843878
- Testing
- COVID Detect
- Where
- United States
- Volunteers
- 326 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Autism Spectrum Disorders, ADHD
Novel Measure of Social Deficits in Children
Autism Spectrum Disorders (ASD) feature impairments in social interaction and communication. Drug and behavioral treatments for ASD are undergoing rapid development, yet our diagnostic tools are not suitable for efficacy…
- Trial name
- OATS (NCT02035176)
- Where
- 2 sites in United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Sedentary Behavior, Affect
Effects of Multi-day Interruptions in Sitting on Type 2 Diabetes-relevant Outcomes in Children
The overall objective of this in-lab randomized controlled trial is to test the efficacy of multi-day interruptions in sedentary behavior vs.
- Conditions
- Sedentary Behavior, Affect, Metabolic Disturbance, Anxiety
- Trial name
- NCT04469790
- Testing
- SIT+WALK, EX
- Where
- United States
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Healthy, Gastric Emptying
A Dose-finding and Feasibility Study for a Prolonged 13C-octanoate Breath Test for Gastric Emptying
The objective of this dose-finding and feasibility study is to establish the optimal 13C-octanoate concentration to be used with slowly infused enteral nutrition to perform a prolonged gastric emptying test using the breath test.
- Trial name
- ANTERO-AC-7 (NCT03410147)
- Testing
- 13C-octanoate breath test for gastric emptying
- Where
- Belgium
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Fatigue
Reliability of a Endurance and a Strength Test for Shoulder Rotation
Introduction: Verification of the progression of individuals submitted to training programs is performed by diagnostic tests with a focus on strength and muscular endurance.
- Trial name
- NCT03923608
- Testing
- Maximal muscle strength Test, Exhaustion test
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- São Paulo State University
Amputation
Active Knee Prosthesis Study for Improvement of Locomotion for Above Knee Amputees
The purpose of this study is to develop a robust, low-power, stable, and light weight, active knee prosthetic device that can dramatically increase gait symmetry and walking economy of a transfemoral amputee during walking.
- Trial name
- NCT00771589
- Testing
- Active Knee Prosthesis
- Where
- 2 sites in United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Providence VA Medical Center
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