Clinical trials: Test Result Management
Hepatic Insufficiency
A Study to Test How Iclepertin is Taken up in the Blood of People With and Without Liver Problems
This study is open to people with and without liver problems. People can join the study if they are 18 to 79 years of age and have a body mass index (BMI) between 18.5 and 35 kg/m2.
- Trial name
- NCT05731895
- Testing
- Iclepertin
- Where
- Germany
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Healthy
Bioequivalence of Ketoprofen Oral Gel vs Ketoprofen Lysine Salt as Granules for Oral Solution
This is a single dose, open-label, randomised, two period, two-way cross-over, two stage bioequivalenve study with the aim to investigate the bioequivalence between a new formulation of ketoprofen 25 mg versus OKI 80 mg granules…
- Trial name
- NCT04678076
- Testing
- Ketoprofen Lysine, Ketoprofen Oral Product
- Where
- Switzerland
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Aziende Chimiche Riunite Angelini Francesco S.p.A
Medication Administration, Mentoring
Pediatric Nursing Students' Self-efficacy Regarding Pediatric Medication Administration and, Clinical Comfort and Worry: A Study on a Two-group Pre-post-test Design Comparing Nurse and Peer Mentoring
Children are a particularly vulnerable population to medication mistakes, and it is critical to improve the self-efficacy, clinical comfort, and worry levels of student nurses who will care with them.
- Conditions
- Medication Administration, Mentoring, Comfort
- Trial name
- NCT05771870
- Testing
- Peer mentoring, Nurse mentoring
- Where
- Turkey (Türkiye)
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Karabuk University
Pharmacogenomic Testing for Medication Management
Reduction of Adverse Drug Events and Readmissions
Pharmocogenomic test assessment in the medication regimen and disease management for patients under drugs known with genetic variation.
- Trial name
- RADAR-PGX (NCT02738047)
- Where
- United States
- Volunteers
- 280,000 people, healthy volunteers welcome
- Sponsor
- ClinLogic LLC
Arthritis Knee, Spine Fusion
Goal-directed vs Preemptive Tranexamic Acid Administration in Non-cardiac Surgery
The present study is a multi-center randomized prospective non-inferiority trial. The study's primary objective is to compare the coagulation profile upon using two different TXA administration strategies: empirical TXA…
- Conditions
- Arthritis Knee, Spine Fusion, Prostate Cancer, Arthritis of Hip
- Trial name
- NCT05957822
- Testing
- TXA, TEG6
- Where
- South Korea
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Konkuk University Medical Center
Hepatic Insufficiency
A Study to Test How BI 1015550 is Taken up in the Blood of People With and Without Liver Problems
This study is open to adults aged 18 years and older. People without liver problems and people who have mild or moderate liver problems can join the study.
- Trial name
- NCT05661344
- Testing
- BI 1015550
- Where
- Germany
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Renal Insufficiency, Healthy
A Study to Test How BI 1015550 is Taken up in the Blood of People With and Without Kidney Problems
This study is open to adults aged 18 years and older. People without kidney problems and people who have moderate or severe kidney problems can join the study.
- Trial name
- NCT05718648
- Testing
- BI 1015550
- Where
- Germany
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Healthy Volunteers
Dose-finding Pharmacokinetic Study in Healthy Males
This is a phase I PK study in healthy males.
- Trial name
- COMDOS1 (NCT03055936)
- Testing
- Levodopa, Carbidopa, ODM-104
- Where
- Germany
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Orion Corporation, Orion Pharma
Alcoholism
Validation of a Test System for Development of Medications for Alcoholism
Using theTEMA (test system for development of medications for alcoholism) it can be shown, that naltrexone administration reduces the willingness to perform work for alcohol infusion in a laboratory experiment.
- Trial name
- TEMANX (NCT02652585)
- Testing
- Naltrexone
- Where
- Germany
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Technische Universität Dresden
Behavior, Child, Dentist-Patient Relations
Preparation Protocol for the First Pediatric Dental Visit
To date, not enough attention has been paid to the role of communication before the first dental visit to encourage the child's cooperation and avoid dysfunctional behaviors.
- Trial name
- PREP (NCT05608720)
- Testing
- Information Booklet
- Where
- Italy
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Bologna
Hyperkyphosis
Postural Management of Hyperkyphosis in Cardiac Rehab Patients
The goal of this clinical trial is to evaluate the efficacy of a home-based exercise program in managing hyperkyphosis, and its impact on physical performance and pulmonary function among cardiac rehabilitation patients.
- Trial name
- NCT06563882
- Testing
- Home-based exercise program, No intervention
- Where
- Israel
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Caregiver, Malignant Neoplasm
Comic Art Creation as Supportive Care in Cancer Patients and Caregivers
This pilot clinical trial studies how well comic art creation works as supportive care in cancer patients and caregivers. Participating in a comic art creation workshop may help patients and their family members or friends share…
- Trial name
- NCT03067766
- Testing
- Art Therapy, Interview, Quality-of-Life Assessment
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- City of Hope Medical Center
Ebola Virus Disease, Marburg Virus Disease
Evaluation of Safety, Tolerability and Immune Responses of Ebola-S and Marburg Vaccines in Healthy Adults
Primary Objective: To evaluate the safety and tolerability of cAd3-EBO-S and cAd3 Marburg vaccines when administered Intramuscular (IM) at a dose of 1 x 10^11 particle units (PU) to healthy adults.
- Trial name
- NCT04723602
- Testing
- cAd3-Marburg, cAd3-EBO-S
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Albert B. Sabin Vaccine Institute
Surgical Blood Loss, Surgical Hemorrhage
TEG Use in Children Undergoing Procedures With High Anticipated Blood Loss
The research team proposes a prospective, observational study to better understand how TEG can be useful in guiding clinical practice in the Main OR for subject's undergoing high transfusion risk surgeries.
- Conditions
- Surgical Blood Loss, Surgical Hemorrhage, Post Operative Hemorrhage
- Trial name
- NCT05379530
- Testing
- Thromboelastography (TEG), Anesthesia Provider Survey
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Healthy
A Study in Healthy People to Test How Empagliflozin is Taken up in the Body When Taken as a Whole Tablet or Dissolved in Water and Mixed With Food
This trial is conducted to test how empagliflozin is taken up in the body when taken as a whole tablet or dissolved in water and mixed with food.
- Trial name
- NCT06962826
- Testing
- Empagliflozin
- Where
- Germany
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Pulmonary Disease, Chronic Obstructive
A Study to Investigate the Safety and Pharmacokinetics of a Single Dose of GSK2256294 in Healthy Young Males and Elderly Subjects
This study will investigate the safety and pharmacokinetics (PK) of a single dose of GSK2256294 in healthy young and elderly subjects to explore the effects of food, gender and age on drug exposure.
- Trial name
- NCT02006537
- Testing
- GSK2256294
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Healthy Volunteer
A Cross-over Study Examining the Bioequivalence of 3 Test Formulations to a Reference Formulation of Alectinib (RO5424802) in Healthy Volunteers
This 2-part, single center, open-label, randomized, single-dose, 4-sequence, 4-period cross-over study will compare the bioequivalence of three test RO5424802 capsule formulations with the reference capsule formulation in healthy…
- Trial name
- NCT02074553
- Testing
- Ro542-4802/F03 (Reference), Ro542-4802/F07 (Test), Ro542-4802/F08 (Test)
- Where
- United States
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Hoffmann-La Roche
Healthy
A Study in Healthy People to Test Whether BI 1291583 Influences the Amount of Dabigatran in the Body
The main objective of this trial is to investigate the effect of a single dose of BI 1291583 on the pharmacokinetics of a single dose of dabigatran, an efflux transporter P-glycoprotein (P-gp) substrate.
- Trial name
- NCT06791187
- Testing
- dabigatran etexilate, BI 1291583
- Where
- Germany
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Healthy
A Study in Healthy Men to Test Whether BI 1815368 Influences the Amount of Metformin in the Body
The main objective of this trial is to investigate the effect on the exposure of metformin in plasma when administered as an oral multiple dose together with multiple oral doses of BI 1815368 (Test, T) as compared to when…
- Trial name
- NCT06655220
- Testing
- Metformin hydrochloride, BI 1815368
- Where
- Germany
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim