Clinical trials: Testicular
Contraception
Manipulation of the Intratesticular Hormonal Milieu With Exogenous Testosterone (HOP 5) Testicular Aspiration Addendum
This study is being offered to all participants of the ACY-5 study as an optional addition to the male contraceptive study in which they participated. Participation is voluntary.
- Trial name
- IHOP-5 (NCT00156650)
- Testing
- Acyline, Testosterone Gel, Depo-Medroxyprogesterone
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Washington
Platinum-resistant Ovarian Cancer, Testicular Cancer
A Phase 1 Study of CTIM-76 in Patients With Recurring Ovarian Cancer and Other Advanced Solid Tumors
This is a Phase 1a/1b, open-label, dose escalation and expansion study to evaluate the safety and efficacy of CTIM-76 (study drug), a CLDN6-directed T cell-engaging bispecific antibody , in participants with…
- Conditions
- Platinum-resistant Ovarian Cancer, Testicular Cancer, Endometrial Cancer
- Trial name
- NCT06515613
- Testing
- CTIM-76
- Where
- 15 sites in United States, United Kingdom
- Volunteers
- 156 people
- Sponsor
- Context Therapeutics Inc.
Non-Hodgkin's Lymphoma, Multiple
Dasatinib for Modulating Immune System After Autologous Stem Cell Transplants for Multiple Myeloma, Non-Hodgkin, or Hodgkin Lymphoma
This study uses a drug called dasatinib to produce an anti-cancer effect called large granular lymphocyte cellular expansion. Large granular lymphocytes are blood cells known as natural killer cells that remove cancer cells.
- Conditions
- Non-Hodgkin's Lymphoma, Multiple, Mycosis Fungoides, Hodgkin's Lymphoma
- Trial name
- NCT01609816
- Testing
- Dasatinib
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Barbara Ann Karmanos Cancer Institute
Azoospermia or Severe Oligozoospermia, Infertility
Fertility Restoration With Autografting of Cryopreserved Immature Testicular Tissue
This is a pilot clinical trial to evaluate the feasibility and outcome of autologous transplantation of immature testicular tissue cryopreserved during childhood as a method of fertility preservation for prepubertal boys in case…
- Conditions
- Azoospermia or Severe Oligozoospermia, Infertility, Autologous Transplantation
- Trial name
- TESTIGRAFT (NCT07542626)
- Testing
- autologous transplantation of cryopreserved testicular tissue
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Cryptorchidism
Shehata Technique in the Treatment of Intra-abdominal Testis
This study focuses on children diagnosed with intra-abdominal cryptorchidism, a condition in which the testicle remains lodged in the abdomen instead of descending to the scrotum.
- Trial name
- INP2024/063 (NCT06862258)
- Testing
- Shehata technique
- Where
- Mexico
- Volunteers
- 30 people
- Sponsor
- National Institute of Pediatrics, Mexico
Childhood Embryonal Tumor, Childhood Extracranial Germ Cell Tumor
Surgery and Combination Chemotherapy in Treating Children With Extracranial Germ Cell Tumors
This phase III trial is studying surgery followed by combination chemotherapy to see how well it works in treating children with germ cell tumors that are not located in the head.
- Conditions
- Childhood Embryonal Tumor, Childhood Extracranial Germ Cell Tumor, Childhood Extragonadal Germ Cell Tumor, Childhood Malignant Ovarian Germ Cell Tumor
- Trial name
- NCT00053352
- Testing
- conventional surgery, cisplatin, etoposide
- Where
- 126 sites in United States, Australia and 4 more
- Volunteers
- 302 people
- Sponsor
- Children's Oncology Group
Germ Cell Tumor, Testicular Tumor
Germ Cell Tumor and Testicular Tumor DNA Registry
This study is being done to create a registry to help us learn more about germ cell tumors (GCT) and other testicular tumors. The registry will include people with these tumors and also relatives and unrelated people without…
- Trial name
- NCT02099734
- Testing
- Questionnaires, sample of blood or saliva
- Where
- 8 sites in United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Chemotherapy-Related Cognitive Impairment, Chemotherapeutic Toxicity
Investigating Cognitive Impairment in Young Patients With Cancer Prospectively
The MyBrain study investigates the brain function of children, adolescents and young adults during and after chemo treatment for cancer.
- Conditions
- Chemotherapy-Related Cognitive Impairment, Chemotherapeutic Toxicity, Chemo-brain, Cancer
- Trial name
- MyBrain (NCT05840575)
- Where
- Denmark
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Testicular Cancer
Unveiling Patient Experiences in Testicular Cancer Clinical Trials
Clinical research participation has historically been heavily biased toward specific demographics. Several people will be invited to enroll in this study so that it may collect a variety of data about testicular cancer clinical…
- Trial name
- NCT05928377
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Power Life Sciences Inc.
Fertility Disorders, Childhood Cancer
Cryopreservation of Prepubertal Testicular Tissue for Preservation of Fertility in Young Boys With Cancer
Prepubertal boys treated for cancer are at risk of infertility as a result of their treatment. At present there are no options to preserve fertility in these boys.
- Trial name
- NCT06063551
- Testing
- Testicular Biopsy
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- University of Edinburgh
Transitional Cell Carcinoma, Renal Cell Cancer
Relationship of Ochratoxin A to Upper Urologic Cancers
This pilot study will explore the relationship of Ochratoxin A (OTA) levels in patients with upper tract transitional cell (TCC), renal cell, and testicular cancers by measuring levels of OTA in serum and tumor samples.
- Conditions
- Transitional Cell Carcinoma, Renal Cell Cancer, Testicular Cancer
- Trial name
- NCT00216801
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Lymphoma, Breast Cancer
Digital Peer Navigation for Adolescents and Young Adults With Cancer
Adolescents and young adults (AYA) diagnosed with cancer experience unique challenges after completing treatment and face distinct barriers to optimal care and support.
- Conditions
- Lymphoma, Breast Cancer, Testicular Cancer, Sarcoma
- Trial name
- NCT06193369
- Testing
- Digital Peer Navigation
- Where
- Canada
- Volunteers
- 138 people
- Sponsor
- University Health Network, Toronto
Breast Cancer, Leukemia
High-Dose Chemotherapy, Total-Body Irradiation, and Autologous Stem Cell Transplantation or Bone Marrow Transplantation in Treating Patients With Hematologic Cancer or Solid Tumors
RATIONALE: Radiation therapy uses high-energy x-rays to damage cancer cells. Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die.
- Conditions
- Breast Cancer, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm
- Trial name
- NCT00060255
- Testing
- busulfan, carboplatin, carmustine
- Where
- United States
- Volunteers
- 451 people
- Sponsor
- Roswell Park Cancer Institute
Inguinal Hernia, Testicular Diseases
Testicular Vascular Evaluation in Patients Undergoing Inguinal Hernia Repair
Patients scheduled to undergo laparoscopic preperitoneal or open inguinal hernia repair will be evaluated by means of scrotal/testicular ecocolordoppler ultrasound investigation before and after surgery in order to rule out the…
- Trial name
- NCT03056027
- Testing
- Ecocolordoppler ultrasound testicular evaluation
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Istituto Auxologico Italiano
Bony Sclerosis, Testicular; Hormone, C
Sex Hormones & Serum Sclerostin Level
The aim of this study is to determine whether plasma sclerostin levels is affected by sex hormones during menstrual cycle. Blood samples will be obtained at the beginning (between 2-5th day), mid (between 11-13th day) and end…
- Trial name
- SHSCL (NCT01418924)
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Bagcilar Training and Research Hospital
Adenocarcinoma of the Bladder, Squamous Cell Carcinoma of the Bladder
Enfortumab Vedotin With or Without Pembrolizumab in Rare Genitourinary Tumors (E-VIRTUE)
Background: Many cancers of the testicles and urinary tract are rare diseases; these are diseases that affect less than 200,000 people in the United States. It can be hard to study treatments for these diseases.
- Conditions
- Adenocarcinoma of the Bladder, Squamous Cell Carcinoma of the Bladder, Testicular Germ Cell Tumors
- Trial name
- NCT06041503
- Testing
- Pembrolizumab, Enfortumab vedotin
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- National Cancer Institute (NCI)
Sarcoma, Multiple Myeloma
Study of F-Fluorodeoxyglucose (FluGlucoScan) in Patients With Known or Suspected Cancers of Low Incidence
Positron Emission Tomography (PET) is a specialised nuclear medicine procedure that uses positron emitting radiolabeled tracer molecules to measure biological activity.
- Conditions
- Sarcoma, Multiple Myeloma, Testicular Neoplasms, Ovarian Neoplasms
- Trial name
- NCT00123773
- Testing
- Positron Emission Tomography
- Where
- Canada
- Volunteers
- 1,075 people
- Sponsor
- AHS Cancer Control Alberta
Testicular Cancer, Testicular Self-Examination
Effects of Testicular Self-Examination Training Methods on Students' Behaviors and Health Beliefs
The goal of this cluster randomized controlled trial is to evaluate and compare the effects of different testicular self-examination (TSE) training methods on university students' health beliefs and self-examination behaviors…
- Conditions
- Testicular Cancer, Testicular Self-Examination, Health Behavior, Health Knowledge, Attitudes, Practice
- Trial name
- NCT07841041
- Testing
- Educational Brochure and Audio Recording, Educational Brochure, Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Yeditepe University
Childhood Acute Lymphoblastic Leukemia in Remission, Childhood Acute Myeloid Leukemia in Remission
Supersaturated Calcium Phosphate Rinse in Preventing Oral Mucositis in Young Patients Undergoing Autologous or Donor Stem Cell Transplant
This randomized phase III trial is studying how well Caphosol rinse works in preventing mucositis in young patients undergoing autologous or donor stem cell transplant.
- Conditions
- Childhood Acute Lymphoblastic Leukemia in Remission, Childhood Acute Myeloid Leukemia in Remission, Childhood Chronic Myelogenous Leukemia, Childhood Myelodysplastic Syndromes
- Trial name
- NCT01305200
- Testing
- supersaturated calcium phosphate rinse, questionnaire administration, quality-of-life assessment
- Where
- 35 sites in United States, Australia and 1 more
- Volunteers
- 226 people
- Sponsor
- Children's Oncology Group
Ovarian Neoplasms, Endometrial Neoplasms
A Study of SGN-ALPV in Advanced Solid Tumors
This study will test the safety of a drug called SGN-ALPV in participants with solid tumors. It will also study the side effects of this drug. A side effect is anything a drug does to your body besides treating your disease.
- Conditions
- Ovarian Neoplasms, Endometrial Neoplasms, Carcinoma, Non-Small-Cell Lung, Stomach Neoplasms
- Trial name
- NCT05229900
- Testing
- SGN-ALPV
- Where
- 13 sites in United States, Canada and 3 more
- Volunteers
- 43 people
- Sponsor
- Seagen Inc.