Clinical trials: Testing
ASCVD, ASCVD Management
Coronary Artery Calcium (CAC) Testing in Primary Care
The goal of this study is to improve how primary care providers identify and manage patients at risk for heart disease. One tool that can help with this is a coronary artery calcium (CAC) test, which looks for calcium buildup in…
- Conditions
- ASCVD, ASCVD Management, Coronary Artery Calcium, Hyperlipidemia
- Trial name
- NCT07868809
- Testing
- Our Practice Advisory (OPA)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Weill Medical College of Cornell University
Lung Cancer, Red Blood Cells
The Red Blood Cells Based Blood Test for Lung Cancer EARLY Detection
This study plan to enroll 852 patients with pulmonary nodules smaller than 3 cm in diameter, whose DNA and RNA will be extracted from mature red blood cells isolated from peripheral blood.
- Conditions
- Lung Cancer, Red Blood Cells, Methylation
- Trial name
- NCT05380999
- Testing
- Methylation tests of nucleic acids extracted from mature red blood cells (RBCs)
- Volunteers
- 852 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
COPD, Pulmonary Rehabilitation
Tele-based Resisted Exercise for COPD
The present study aims to investigate the effect of six weeks tele-based resisted exercises on cardiopulmonary function, quality of life, muscle strength and functioanl performance among patients with chronic obstructive…
- Conditions
- COPD, Pulmonary Rehabilitation, Telerehabilitation, Cardiopulmonary Exercise Test
- Trial name
- NCT04870632
- Testing
- Education, Video-based pulmonary rehabilitation, Booklet-based pulmonary rehabilitation
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- National Cheng-Kung University Hospital
Pregnancy
Telemedicine Medical Abortion Service Using the "No-test" Protocol in Ukraine and Uzbekistan.
The goal of this study is to pilot and evaluate a telemedicine medical abortion service delivery that allows remote communication between the woman and provider and limits medically unnecessary in-person visits to health or…
- Trial name
- NCT05028387
- Testing
- medical abortion
- Where
- 4 sites in Ukraine, Uzbekistan
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Drug Allergy, Cephalosporin Allergy
Optimizing the Diagnostic Approach to Cephalosporin Allergy Testing
Cephalosporin antibiotics are commonly used but can result in allergic reactions and anaphylaxis. There is no clear diagnostic approach for cephalosporin-allergic patients, and guidance for the use of other antibiotics in…
- Conditions
- Drug Allergy, Cephalosporin Allergy, Drug Hypersensitivity, Antibiotic Allergy
- Trial name
- DACAT (NCT06406114)
- Testing
- Beta-lactam antibiotic (cefazolin, cefuroxime, cefotaxime, ceftazidime, ceftriaxone, cefepime, pre-pen, penicillin G, ampicillin, and histamine) double-blind skin testing
- Where
- 6 sites in United States
- Volunteers
- 300 people
- Sponsor
- Massachusetts General Hospital
Imipramine, Photodynamic Therapy
The Effect of Topical Imipramine on Pain and Effectiveness of Topical Photodynamic Therapy
The purpose of this study is testing the use of topical Imipramine in combination with topical photodynamic therapy's (PDT) effect on pain following treatment.
- Conditions
- Imipramine, Photodynamic Therapy, Actinic Keratosis
- Trial name
- NCT05688904
- Testing
- Imipramine, Vehicle
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Wright State University
Outbreaks
Respiratory Outbreak Mitigation in Long-Term Care Using Point-of-Care Testing
Outbreaks of seasonal respiratory viruses can spread rapidly in long-term care homes. Timely results for diagnostic tests remains a challenge for respiratory viruses due to the logistics of using a reference laboratory with…
- Trial name
- PROMPT-LTC (NCT06660433)
- Testing
- Point-of-care respiratory test platform, Existing respiratory virus testing platform
- Where
- 2 sites in Canada
- Volunteers
- 24 people
- Sponsor
- Michael Garron Hospital
Autism Spectrum Disorder
Evaluation of Behavioural Psycho & Physiological Responses in People With ASD During a Blood Test in Routine Care Practice
The project is a prospective study designed to characterize behaviour and its psycho-physiological correlates of participants with ASD (children and adults) in comparison with subjects without ASD matched in age during blood test…
- Trial name
- AUTICOPP (NCT04638452)
- Testing
- Video & movements recording, Questionnaires
- Where
- France
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Charles Perrens, Bordeaux
Dental Pulp Test
Diagnostic Device for the Assessment of Pulpal Blood Flow
The purpose of this study is to assess tooth health by using a pulse oximeter which measures the blood flow within the tooth. This method is not currently being used in dentistry.
- Trial name
- NCT03578549
- Testing
- Pulse Oximetry
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Proton Pump Inhibitors, Gastroesophageal Reflux Disease
Should I Continue Taking My Acid Reflux Medication? Development and Pilot Testing of a Patient Decision Aid
BACKGROUND: Proton pump inhibitors (PPIs) treat problems such as gastroesophageal reflux disease (GERD). In many patients with mild or moderate GERD, PPIs should be used for 1-2 months but are often continued longer…
- Trial name
- NCT02558049
- Testing
- Decision aid
- Where
- 3 sites in Canada
- Volunteers
- 12 people
- Sponsor
- University of Ottawa
Human Papillomavirus Infection, Cervical Cancer
Clinical Evaluation of Detection of High Risk HPV in Urine
Cervical cancer is one of the most common tumors in women, which seriously threatens women's life quality and safety. Human papilloma virus (HPV) infection is the most common cause of cervical cancer.
- Conditions
- Human Papillomavirus Infection, Cervical Cancer, Human Papilloma Virus, Negative for Intraepithelial Lesion or Malignancy
- Trial name
- Urine-hrHPV (NCT05210348)
- Where
- 3 sites in China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Peking University People's Hospital
Food Allergies
Endophenotyping for Plant-based Food Allergy Diagnosis, Tolerance Biomarkers, and Mechanisms in Microneedle Immunotherapy
In relation to the prognosis of vegetable FA (VFA), in contrast to other food allergies (FA), which disappear naturally with time, VFA tends to persist into adulthood and to the appearance of new sensitizations to other…
- Trial name
- NCT06997432
- Testing
- Dietary intervention
- Where
- Spain
- Volunteers
- 32 people
- Sponsor
- Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud
COPD, Pulmonary Disease
The Application and Analysis of HHHFNC in Walking Test of Pulmonary Rehabilitation
The aim of this study is to investigate the use heated humidified high-flow nasal cannula (HHHFNC) in pulmonary rehabilitation and analysis of cardiopulmonary parameters in adult patients.
- Conditions
- COPD, Pulmonary Disease, Rehabilitation
- Trial name
- NCT03863821
- Testing
- HHHFNC
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Fu Jen Catholic University
Health Behavior
Experiences With a Genetic Test for Personalized Nutrition Test for Personalized Nutrition
The investigators will use a web-based survey to collect data on individual attitudes and self-reported health behaviour changes following genetic testing for personalized nutrition.
- Trial name
- NCT02440698
- Testing
- Genetic test for personalized nutrition
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Colorectal Cancer
An Evaluation of a Multi-target Stool DNA (Mt-sDNA) Test, Cologuard, for CRC Screening in Individuals Aged 45-49 and at Average Risk for Development of Colorectal Cancer: Act Now
The primary objective is to confirm the specificity of a multi-target stool DNA test (mt-sDNA), Cologuard, in an average risk population, ages 45-49.
- Trial name
- NCT03728348
- Testing
- mt-sDNA screening test, Colonoscopy
- Where
- 39 sites in United States
- Volunteers
- 983 people, healthy volunteers welcome
- Sponsor
- Exact Sciences Corporation
Anterior Cruciate Ligament Reconstruction (ACLR), Anterior Cruciate Ligament Reconstruction Rehabilitation
The Effect of Isokinetic Vs Plyometric Training in Post-ACLR Surgery
The primary goal of this RCT is to evaluate the effects of isokinetic training compared to plyometric training in patients aged 18-40 years who have undergone ACLR surgery.
- Conditions
- Anterior Cruciate Ligament Reconstruction (ACLR), Anterior Cruciate Ligament Reconstruction Rehabilitation, Anterior Cruciate Ligament/Surgery, Anterior Cruciate Ligament (ACL) Reconstruction Surgery
- Trial name
- NCT07862868
- Testing
- Isokinetic Training, Plyometrics Training
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Sinusitis
Xolair in Patients With Chronic Sinusitis
The purpose of this study is to determine if treatment with the anti-IgE antibody, Xolair (omalizumab), will improve objective and subjective evidence of chronic sinusitis.
- Trial name
- NCT00117611
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Chicago
Marriage, Family Relations
Testing the Effectiveness of Integrating Relationship Education Into an Existing Workforce Readiness Program
The project will test the strategy of integrating 25 hours of relationship education into an existing employment program for low-income individuals ages 18-30.
- Trial name
- NCT02829411
- Testing
- Workforce Readiness Program, Relationship education
- Where
- United States
- Volunteers
- 909 people, healthy volunteers welcome
- Sponsor
- Mathematica Policy Research, Inc.
Pulmonary Disease, Chronic Obstructive, Lung Diseases, Obstructive
Diagnosing Obstructive Lung Disease With Point of Care Ultrasound
The objective of this study is to evaluate the diagnostic accuracy of Point of Care Ultrasound (POCUS) in identifying obstructive lung diseases (OLDs), using pulmonary function tests (PFTs) as the gold standard for comparison.
- Conditions
- Pulmonary Disease, Chronic Obstructive, Lung Diseases, Obstructive, Asthma, COPD
- Trial name
- NCT06251271
- Testing
- Point-of-Care Ultrasound
- Where
- Israel
- Volunteers
- 301 people
- Sponsor
- Soroka University Medical Center
Syphilis, Syphilis, Congenital
Congenital and Maternal Point of Care Rapid Testing for Syphilis Study, Uganda
Syphilis is an infection which affects about 1 in 25 pregnant women in Uganda. If the infection is not diagnosed and treated this can be a risk to the mother and unborn baby's health.
- Trial name
- COMPARTS (NCT07173764)
- Where
- Uganda
- Volunteers
- 24 people
- Sponsor
- St George's, University of London