Clinical trials: Testosterone Replacement Therapy
Arthroplasty, Replacement, Hip
Does Testosterone Therapy Improve Patient-Reported Outcomes in Age-Related Testosterone Deficient Patients Undergoing Total Hip Replacement: A Randomized-Controlled Trial
This randomized-controlled trial will study on the effect of testosterone therapy on patients undergoing total hip replacement. Subjects will be male patients > 50 years with testosterone deficiency undergoing total hip…
- Trial name
- NCT05722301
- Testing
- Testosterone Therapy, No Testosterone Therapy
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- American Hip Institute
Puberty Delayed
Pubertal Replacement In Boys Study Nebido and Testoviron Depot Treatment
In this prospective open clinical study, Pubertal Replacement in Boys Study (PRIBS), boys 14-16 years with delayed puberty in terms of slow pubertal progression, were randomized to SoC treatment with TE: Testostoviron depot® 75…
- Trial name
- NCT05417035
- Testing
- Nebido
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- NU-Hospital Organization, Sweden
Menopause, Perimenopausal Disorder
A New Hormone Replacement Paradigm: Physiologic Restoration Study
This is a three-year, prospective, observational study looking at the benefits of rhythmically dosed, bio-identical hormones compounded in a carrier cream in 100 symptomatic peri and postmenopausal women.
- Conditions
- Menopause, Perimenopausal Disorder, Menopause Related Conditions
- Trial name
- NCT04190927
- Testing
- Compounded topical estradiol and compounded topical progesterone in a carrier cream
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Women's Hormone Network
Hypogonadism
A Study to Test a Measure of Symptoms of Older Men With Low Testosterone On and Off Testosterone Replacement Treatment (P05815)
Hypogonadal males, particularly those whose condition manifested later in life, may experience common symptoms associated with their hypogonadism. Questionnaires developed to assess these symptoms need to be tested.
- Trial name
- NCT00254553
- Testing
- Testim 1% (testosterone gel)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Menopause
A Comparison of Patch vs. Pill Estrogen Therapy on Testosterone Levels and Thyroid Tests in Menopausal Women
This study compares the effects of 12 weeks of treatment with transdermal versus oral estrogen therapy on testsoterone levels and thyroid tests in healthy, naturally menopausal women.
- Trial name
- NCT00224094
- Testing
- Premarin® (oral) vs. Alora® (transdermal)
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Watson Pharmaceuticals
Secondary Hypogonadism
The Effect of Testosterone Replacement on the High Density Lipoprotein Cholesterol Subgroups
The study is designed to answer the following questions: 1. Is there any difference between the compositions of the HDL cholesterol subpopulations of patients with hypogonadism and the healthy controls. 2.
- Trial name
- NCT01454011
- Testing
- Testosteron 250mg injection, Testosterone 50mg transdermal application
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Gulhane School of Medicine
Healthy
An Open-Label Study of Serum Testosterone Levels in Non-dosed Females After Secondary Exposure to Testosterone Gel 1.62% Applied to the Upper Arms and Shoulders and Use of a T-shirt Barrier
Single-center, single dose, open-label study in healthy male and female volunteers to further characterize the transfer potential of Testosterone Gel 1.62% formulation.
- Trial name
- NCT01130298
- Testing
- Testosterone Gel 1.62%
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- AbbVie
Hypogonadism, Male
Single-Dose Pharmacokinetics of Oral Testosterone Undecanoate With and Without Concomitant Inhibition of UGT2B17
This study will be performed in normal men whose endogenous testosterone production has been temporarily suppressed by the administration of a single dose of 120 mg of the oral GnRH antagonist Relugolix, which is approved for the…
- Trial name
- OralT12 (NCT06312761)
- Testing
- Relugolix 120Mg Tab, Curcumin, Testosterone Undecanoate 237 MG Oral Capsule
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Washington
Hypoactive Sexual Desire Disorder
A Pharmacokinetic (PK) Study to Compare the Absorption of Two Formulations of Transdermal Testosterone Spray and Intrinsa®
The purpose of this study is to determine if the absorption of the testosterone spray is the same as the Intrinsa® Patch.
- Trial name
- NCT01096329
- Testing
- Testosterone Spray 5% and 1%, Intrinsa® Patch and Testosterone Spray 5%, Intrinsa® Patch and Testosterone Spray 1%
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- VIVUS LLC
Hypogonadotrophic Hypogonadism
Endothelial Dysfunction, Inflammation and Insulin Resistance in Congenital Hypogonadism and Effect of Testosteron Replacement Therapy
The study searched for answers to two questions 1. Is there endothelial dysfunction, inflammation and insulin resistance in patients with congenital hypogonadotropic hypogonadism? 2.
- Trial name
- NCT02171390
- Testing
- Testosterone 250mg injection, Testosteron 50 mg transdermal gel
- Where
- Turkey (Türkiye)
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Gulhane School of Medicine
Healthy, Osteoporosis
Hormone Replacement in Young Women With Premature Ovarian Failure
The human ovary produces male sex hormones (androgen) and female sex hormones (estrogen). Currently, androgen is not included in hormone replacement therapy for women with premature ovarian failure.
- Conditions
- Healthy, Osteoporosis, Premature Ovarian Failure
- Trial name
- NCT00001951
- Testing
- TMTDS
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Hypogonadism
Study of Serum Testosterone Levels in Non-dosed Females After Secondary Exposure
To further characterize the transfer potential of marketed testosterone gel and new 1.62% formulation.
- Trial name
- NCT00998933
- Testing
- Testosterone gel 1.62%
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Solvay Pharmaceuticals
Men With Low Testosterone Levels
Study to Determine the Effects of Testosterone Replacement Therapy in Aging Men With Androgen Deficiency
The T-001 study is a placebo-controlled investigation of the effects of injectable testosterone replacement therapy on prostate tissues of aging men with low testosterone levels.
- Trial name
- NCT00161304
- Testing
- Testosterone Enanthate
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Leonard S. Marks, M.D.