Clinical trials: Therapeutic Endoscopy
Chronic Pain, Bone Marrow Oedema
TEP Versus Open Repair of Sportsman's Hernia
Sportsman's hernia causes chronic groin pain in physically active adults. Open hernia repair without mesh or laparoscopic technique with mesh have been advocated in the treatment of sportsman's hernia.
- Trial name
- sports hernia (NCT01876342)
- Testing
- open repair, endoscopic TEP repair
- Where
- Finland
- Volunteers
- 60 people
- Sponsor
- Kuopio University Hospital
Submucosal Esophageal Adenocarcinoma, Barrett Esophagus
Prospective Endoscopic Follow-up of Patients With Submucosal and High Risk Mucosal Esophageal Adenocarcinoma
Aim of this prospective multicenter study is to evaluate the safety of an endoscopic follow-up strategy in patients treated with endoscopic resection (ER) for submucosal or high-risk mucosal esophageal adenocarcinoma (T1bN0M0 or…
- Conditions
- Submucosal Esophageal Adenocarcinoma, Barrett Esophagus, High-risk Mucosal Esophageal Adenocarcinoma
- Trial name
- PREFER (NCT03222635)
- Testing
- Endoscopic follow-up
- Where
- 20 sites in Australia, Belgium and 4 more
- Volunteers
- 225 people
- Sponsor
- Amsterdam UMC
Obesity
A Feasibility Study for the Treatment of Primary Obesity
This study has been expanded to a four center, open-label, 2-group randomized pilot study evaluating a treatment for obesity.
- Trial name
- NCT03837691
- Testing
- Placement of Snowshoe Suture Anchors, Moderate Intensity Diet & Exercise Program
- Where
- 4 sites in United States
- Volunteers
- 40 people
- Sponsor
- USGI Medical
Endoscopic Biliary Sphincterotomy, Bleeding
Antihemostatic Therapy and Endoscopic Biliary Sphincterotomy Induced Bleeding
The aim of the study is to observe the effects of antihemostatic therapy including nonsteroidal antiinflammatory, anticoagulant and antiaggregant therapy and other patient and procedure related factors on the risk of endoscopic…
- Trial name
- NCT01098617
- Where
- Turkey (Türkiye)
- Volunteers
- 350 people
- Sponsor
- Yuksek Ihtisas Hospital
Esophageal and Gastric Varices
Comparison of Endoscopic Band Ligation Plus 24-hour Versus 72-hour Terlipressin Therapy
In the Western world, liver cirrhosis is a significant issue. Acute variceal bleeding (AVB) is a considerable complication of cirrhosis associated with high mortality.
- Trial name
- NCT05331768
- Testing
- banding ligation plus terlipressin infusion
- Where
- Mexico
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Instituto Mexicano del Seguro Social
Crohn's Disease
A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study of ABT-494 for the Induction of Symptomatic and Endoscopic Remission in Subjects With Moderately to Severely Active Crohn's Disease Who Have Inadequately Responded to or Are Intolerant to Immunomodulators or Anti-TNF Therapy
To determine the efficacy and safety of multiple doses of ABT-494 in subjects with moderately to severely active Crohn's Disease with a history of inadequate response to or intolerance to Immunomodulators or anti-Tumor Necrosis…
- Trial name
- NCT02365649
- Testing
- ABT-494
- Volunteers
- 220 people
- Sponsor
- AbbVie
Cholangiocarcinoma
Comparison of Biliary Stenting Alone vs. Stenting With Photodynamic Therapy (PDT) During ERCP
This study entails retrospective and prospective review of data from a database protocol. Data gathered will be then analyzed for a set amount of patients. In this study, the investigators will compare biliary stenting vs.
- Trial name
- PDT (NCT01439685)
- Where
- United States
- Sponsor
- Weill Medical College of Cornell University
Rectal Prolapse
TEM Assisted Perineal Rectopexy in Treatment of Rectal Prolapse
Curvilinear incision in the postanal space, through the intersphincteric plane, insertion of Proctoscope of TEM technique and dissection till sacral promontory, insertion of mesh between the rectum and sacrum, post anal repair…
- Trial name
- NCT02609555
- Testing
- TEM perineal rectopexy
- Where
- Egypt
- Volunteers
- 7 people
- Sponsor
- Mansoura University
Vesico-Ureteral Reflux
Endoscopic Injection of Dextranomer/Hyaluronic Acid Versus Ureteral Reimplantation In Treatment of Vesicoureteral Reflux
In this study, the investigators aim to compare the outcomes of Dextranomer/hyaluronic acid (Dexell®) and extravesical reimplantation (Lich- Gregoir) procedures for primary vesicoureteral reflux (VUR) grades III and IV in…
- Trial name
- NCT04798443
- Testing
- subureteral endoscopic Injection of Dextranomer/Hyaluronic acid (Dexell), open ureteral reimplantation (Lich-Gregoir)
- Volunteers
- 60 people
- Sponsor
- Elsayed Salih
Gynecomastia
Comparison of Endoscopic and Open Surgery for Gynecomastia
The goal of this observational study is to compare the clinical outcomes, safety, and patient satisfaction of endoscopic versus conventional open surgical techniques in adult male patients undergoing surgery for gynecomastia.
- Trial name
- NCT07653152
- Testing
- Endoscopic Nipple-Areola Complex-Preserving Mastectomy, Conventional Open Nipple-Areola Complex-Preserving Mastectomy
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Antalya City Hospital
Postoperative Complications, Respiratory Depression
Comparison of Remimazolam and Propofol in Endoscopic Examinations and Treatments
This study aims to evaluate the efficacy and safety of Remimazolam, either used alone or in combination with Propofol, for moderate sedation anesthesia during endoscopic therapies or examinations.
- Conditions
- Postoperative Complications, Respiratory Depression, Postoperative Nausea, Vomiting
- Trial name
- Remimazolam (NCT06777758)
- Testing
- Remimazolam, Propofol
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- Kaohsiung Veterans General Hospital.
Liver Cirrhosis, Hepatoma
A Trial of EVL\GVS Alone vs. EVL\GVS Combined Propranolol
New strategy to improve the outcomes in patients with HCC and acute variceal bleeding. NSBB added to endoscopic ligation may further reduce rebleeding in cirrhotic patients.
- Trial name
- NCT01298284
- Testing
- propranolol
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Gastric Fistula
Endoscopic Treatment of Intestinal Fistulas and Perforations
Background: T-shaped tissue anchors have promise to close incisions and perforations of the intestines securely. The closure of perforations, gastro-gastric, or intestinal fistulas usually requires invasive open or laparoscopic…
- Trial name
- NCT00835458
- Testing
- gastro-gastric fistula closure
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Legacy Health System
Pneumothorax
Prevention of Pneumothorax Following Endoscopic Valve Therapy in Patients With Severe Emphysema
Endoscopic valve therapy is an effective therapy for patients with severe emphysema and low interlobar collateral ventilation. Although, valve therapy is a minimal-invasive treatment approach, it is associated with complications…
- Trial name
- NCT03034421
- Testing
- Bed rest
- Where
- Germany
- Volunteers
- 38 people
- Sponsor
- Heidelberg University
Dyspepsia, Gastroesophageal Refluxdisease
Study of Long-Term Use of Proton-Pump-Inhibitors in General Practice
The primary purpose of the study is to determine the effect of esomeprazole compared to placebo in patients from general practice who have previously been treated with proton-pump-inhibitors (PPI) and who have no upper endoscopic…
- Conditions
- Dyspepsia, Gastroesophageal Refluxdisease, Ulcer
- Trial name
- NCT00363701
- Testing
- esomeprazole
- Where
- Denmark
- Volunteers
- 150 people
- Sponsor
- Glostrup University Hospital, Copenhagen
Hernia, Ventral, Rectus Diastasis
Endoscopic eTEP Versus Open Rives-Stoppa
Observational cohort study (partially retrospective, partially prospective) comparing the endoscopic extended totally extraperitoneal prosthesis (eTEP) repair for midline abdominal hernias to open Rives-Stoppa repair (control).
- Trial name
- NCT05446675
- Testing
- Endoscopic eTEP, Open Rives-Stoppa
- Where
- Belgium
- Volunteers
- 60 people
- Sponsor
- AZ Alma
Peptic Ulcer Hemorrhage
Intravenous Proton Pump Inhibitor for Peptic Ulcer Bleeding
A large dose of PPI is effective in preventing peptic ulcer rebleeding. The investigators hypothesize that 40 mg/q6h pantoloc is equivalent to 8mg/h pantoloc in preventing rebleeding.
- Trial name
- PPI (NCT00731601)
- Testing
- pantoprazole
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- Lotung Poh-Ai Hospital
Bleeding Peptic Ulcers Disease
Optimal Dose of Omeprazole After Endoscopic Treatment of Bleeding Peptic Ulcers
Bleeding peptic ulcers are one of the major causes of morbidity and mortality for hospital emergency admissions.The initial treatment is endoscopic therapy followed by intravenous omeprazole.
- Trial name
- NCT00519519
- Testing
- Omeprazole
- Where
- 4 sites in Singapore
- Volunteers
- 126 people
- Sponsor
- Singapore General Hospital
Oesophageal Cancer, Oesophageal Disease
EndoVE endosCopic Treatment for Oesophageal and Gastric canceR
This project aims to establish the safety and efficacy of treating patients with inoperable oesophageal cancer or gastric cancer, using an endoscopic electroporation system (EndoVE) to facilitate direct chemotherapy tumour…
- Conditions
- Oesophageal Cancer, Oesophageal Disease, Gastric Cancer
- Trial name
- VECTOR (NCT04649372)
- Testing
- EndoVE
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Mirai Medical
Antro-pyloric and/or Duodenal Benign or Malignant Obstructions
Endoscopic Gastroenteric Anastomosis With New Tissue Apposing Stent in the Management of Antro-pyloroduodenal Obstruction : Evaluation of Feasibility, Efficacy and Tolerance.
Achieving gastro-jejunal or duodenal anastomosis (GJA ) by exclusive endoscopically is a real goal for many years in the development and research of the transluminal endoscopic surgery (N.O.T.E.S).
- Trial name
- NCT02562157
- Testing
- HYALURONIQUE ACIDE
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Assistance Publique Hopitaux De Marseille