Clinical trials: Therapeutic Endoscopy
Peptic Ulcer Bleeding
Doppler-guided Endoscopic Treatment in Peptic Ulcer Bleeding
The present study is a randomized controlled trial (RCT) that examines if the outcome of peptic ulcer bleeding could be improved by use of doppler-guided endoscopic treatment.
- Trial name
- NCT02434978
- Testing
- Supplementary endoscopy with doppler-guided therapy, IV. PPI, Endoscopic treatment at primary endoscopy
- Where
- 2 sites in Denmark
- Volunteers
- 125 people
- Sponsor
- Odense University Hospital
Achalasia, Gastric Fistula
Outcome Analysis of POEM and Endoluminal Therapies
Evaluation of current and newly developed endoluminal therapies in the management of Upper and Lower GI conditions.
- Conditions
- Achalasia, Gastric Fistula, Weight Gain After Primary Weight Loss Surgery, Marginal Ulcer
- Trial name
- NCT03123835
- Testing
- Endoscopic Intervention
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Obesity Type 2 Diabetes Mellitus
Endoscopic Sleeve Gastroplasty Plus Duodenal pulsENDO for Obese T2DM
This study is designed to evaluate the efficacy, safety, and mechanisms of combining ESG and pulsENDO procedure in obese patients with T2DM
- Trial name
- DRAGON (NCT07660445)
- Testing
- Endoscopic sleeve gastroplasty plus duodenal recellularization via electroporation therapy (pulsENDO)
- Where
- Hong Kong
- Volunteers
- 20 people
- Sponsor
- Chinese University of Hong Kong
Chronic Rhinosinusitis (Diagnosis)
Comparison of Topical Therapies in Post op Endoscopic Sinus Surgery Patients
The goal of the study is to compare postoperative symptom scores and endoscopy findings between in patients who receive either nasal saline rinses, saline + budesonide, and saline + topical antibiotics and budesonide following…
- Trial name
- NCT03303677
- Testing
- Saline Nasal, Budesonide Nasal, Topical Antibacterial (Product)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Florida
Obesity
ENDObesity® II Study: TransPyloric Shuttle® System for Weight Loss
The purpose of this clinical research trial is to study safety and effectiveness of the TransPyloric Shuttle System (TPSS) for weight reduction in patients who are considered medically obese.
- Trial name
- NCT02518685
- Testing
- TransPyloric Shuttle, Lifestyle Counseling
- Where
- 9 sites in United States
- Volunteers
- 302 people
- Sponsor
- BaroNova, Inc.
Lacrimal Duct Obstruction
A Comparative Study of Two Endoscopic Operations for Lacrimal Duct Obstruction
To compare the clinical effects between the silicone nasolacrimal intubation under nasoendoscopy and dacryocystorhinostomy on patients with lacrimal duct obstruction.
- Trial name
- ACSOTEOFLDO (NCT02636257)
- Testing
- Recessive Spherical Headed Silicone Intubation, Dacryocystorhinostomy
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Third Affiliated Hospital, Sun Yat-Sen University
Cirrhosis
Propofol Versus Midazolam for Upper Endoscopy in Cirrhotic Patients
Upper GI endoscopy is often performed in patients with chronic liver disease to screen for esophageal and gastric varices. The purpose of this study is to compare propofol to midazolam for sedation in patients with chronic liver…
- Trial name
- NCT01141036
- Testing
- propofol, Midazolam
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Ziv Hospital
Esophageal and Gastric Varices, Liver Cirrhosis
Pantoprazole After Prophylactic Endoscopic Variceal Treatment
Traditionally, it is considered that gastric acid delays ulcer healing, and acid suppression can reduce the risk of post-banding ulcer bleeding and promote mucosal healing at the ulcer site.
- Trial name
- NCT07248722
- Testing
- Pantoprazole
- Where
- China
- Volunteers
- 208 people
- Sponsor
- General Hospital of Shenyang Military Region
Gastric Varices Bleeding
Detachable Clip-assisted Endoscopic Cyanoacrylate Injection in the Treatment of Gastric Varices
A single-arm exploratory clinical study design was used to evaluate the safety and efficacy of a "modified sandwich injection" of tissue glue assisted by a detachable clip for the treatment of gastric varicose veins.
- Trial name
- NCT06670157
- Testing
- Detachable Clip
- Where
- China
- Volunteers
- 6 people
- Sponsor
- Yu Chang
Hemorrhoids
Comparison Between Two Endoscopic Treatments of Bleeding Internal Hemorrhoids:Band Ligation and Electrocoagulation Probe
The purpose of this study is to determine which treatment, band ligation (placing rubber bands around the hemorrhoids) or BICAP electrocoagulation (using electricity to cauterize) is safer and more effective endoscopic treatment…
- Trial name
- NCT00630669
- Testing
- Rubber band ligation, Bipolar coagulation
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of California, Los Angeles
Gastrointestinal Neoplasms, Biliary Tract Neoplasms
Endoscopic Stenting of Gastrointestinal Cancer
Obstruction of the digestive tract is a frequent cause of morbidity in patients with gastrointestinal cancer.Palliative endoscopic treatment with self- expanding metal stents(SEMS)is an alternative to palliative surgery and other…
- Trial name
- NCT00422409
- Testing
- Endoscopic stenting
- Where
- 7 sites in Norway
- Volunteers
- 270 people
- Sponsor
- Ullevaal University Hospital
Obstructive Sleep Apnoea, Sleep-Disordered Breathing
Drug-Induced Sleep Endoscopy for the Optimisation of Treatment of Patients With Obstruction Sleep Apnoea
The main diagnostic challenge in patients with OSA (obstructive sleep apnea) is to determine the location of obstruction of the upper airway during sleep.
- Trial name
- NCT02855515
- Testing
- Short-time diagnostic anaesthesia
- Where
- Czechia
- Volunteers
- 120 people
- Sponsor
- University Hospital Ostrava
Crohn Disease (CD), Ulcerative Colitis (UC)
IBD Biomarker Discovery and Validation Platform
The goal of this observational study is to establish a multicenter prospective clinical and biospecimen platform for biomarker discovery and validation in inflammatory bowel disease, including Crohn's disease and ulcerative…
- Conditions
- Crohn Disease (CD), Ulcerative Colitis (UC), Inflammatory Bowel Diseases (IBD)
- Trial name
- IBD-BIOP (NCT07686406)
- Where
- 2 sites in China
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Peptic Ulcers
Comparison of Intravenous Omeprazole to Ranitidine on Recurrent Bleeding After Endoscopic Treatment of Bleeding Ulcer
The present study will compare the hemostasis-maintaining effects of intravenous omeprazole and ranitidine in patients with upper gastrointestinal hemorrhage that have undergone endoscopic hemostasis, to establish which…
- Trial name
- NCT00247130
- Testing
- Omeprazole, Ranitidine
- Where
- Japan
- Sponsor
- Keio University
Endoscopic Ultrasound
High Flow Nasal Cannula Compared to Standard Oxygen for Endoscopic Ultrasound
The purpose of the study is to evaluate the use of high flow nasal cannula versus standard oxygen therapy for high-risk patients undergoing endoscopy procedures.
- Trial name
- NCT06704867
- Testing
- High flow nasal cannula
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Mayo Clinic
Pancreatic Mass
Contrast Enhanced Harmonic Endoscopic Ultrasound (CH-EUS), Elastography, and Fractal Analysis in Predicting Pancreatic Cancer Aggressiveness and Response to Therapy.
Contrast enhanced harmonic Endoscopic Ultrasound (CH-EUS) can be used during a conventional EUS examination to correctly identify and target lesions with the help of Ultrasound Contrast Agents.
- Trial name
- CH-E-EUS (NCT05591287)
- Testing
- Contrast enhanced harmonic Endoscopic Ultrasound
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Istituto Clinico Humanitas
Pancreatic Cancer, Endoscopy
Plastic Stent Within a Lumen-Apposing Stent for Malignant Biliary Obstruction
There are doubts concerning the possible benefits derived from the insertion of double-pigtail plastic stents (DPS) within the lumen-apposing metal stents (LAMS) in the EUS-guided transmural biliary drainage (BD).
- Conditions
- Pancreatic Cancer, Endoscopy, Oncologic Disorders, Therapy Related Neoplasms
- Trial name
- LAMSpigBil (NCT04420039)
- Testing
- Endoscopic biliary transmural drainage
- Where
- 3 sites in Spain
- Volunteers
- 39 people
- Sponsor
- Hospital Universitari de Bellvitge
Barrett Syndrome, Barrett's Syndrome
CLE for Assessment of Neoplasia After Mucosal Ablation or Resection of Gastrointestinal Neoplasia
This study focuses on demonstrating the value of probe-based Confocal Laser Endomicroscopy (pCLE) in guiding endoscopic therapeutic procedures in Barrett's Esophagus (BE).
- Conditions
- Barrett Syndrome, Barrett's Syndrome, Barrett's Esophagus, Barrett Esophagus
- Trial name
- CLEAN-MARGIN (NCT01032044)
- Testing
- Standard endoscopic evaluation, pCLE guided evaluation
- Where
- 6 sites in United States, France and 1 more
- Volunteers
- 164 people
- Sponsor
- Mauna Kea Technologies
Refractory Epilepsy
Deep Brain Stimulation of the Anterior Nucleus of the Thalamus in Intractable Epilepsy
Deep Brain Stimulation (DBS) of the anterior nucleus of the thalamus (ANT) has been proposed in patients with severe intractable epilepsy.
- Trial name
- NCT04771065
- Where
- France
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Stenosis of the Bilio-biliary Anastomosis After Orthotopic Liver Transplantation
cSEMS vs. NEPS in Stricture of Biliary Anastomosis After Liver Transplantation
Stenosis at the bilio-biliary anastomosis occurs in up to 30% of patients after orthotopic liver transplantation. This study compares endoscopic treatment with implantation of multiple plastic endoprostheses vs.
- Trial name
- NCT01393067
- Testing
- Non-expandable plastic stent (plastic endoprosthesis), Covered self-expandable metal stent (cSEMS)
- Where
- 4 sites in Finland, Germany and 1 more
- Volunteers
- 60 people
- Sponsor
- Johann Wolfgang Goethe University Hospital