Clinical trials: Therapeutic Endoscopy
Hypoxemia
Anesthesia Endoscope Mask is Applied to Sedation Upper Gastrointestinal Endoscopic Diagnosis and Treatment
To investigate the efficacy and safety of new-type mask compared with nasal tube oxygen delivery in patients undergoing sedation of upper gastrointestinal endoscopy
- Trial name
- NCT06085859
- Testing
- Routine nasal catheter group, Mask group
- Where
- 5 sites in China
- Volunteers
- 1,208 people, healthy volunteers welcome
- Sponsor
- Sichuan Provincial People's Hospital
Colorectal Lesions
Assessment of the EndoR System in ESD for Colorectal Lesions
Gastrointestinal (GI) cancers are common and significant causes of cancer death worldwide. GI cancers grow from the mucosal layer.
- Trial name
- NCT07405203
- Testing
- EndoR Surgical System
- Where
- Hong Kong
- Volunteers
- 6 people
- Sponsor
- Chinese University of Hong Kong
Pancreatic Cyst
Safety and Efficacy of EUS-RFA in the Treatment of Pancreatic Lesions: A Prospective Registry
Purpose: The purpose of this registry is to track the clinical outcomes and progression of patients with pancreatic lesions receiving endoscopic ultrasound (EUS)-based radiofrequency ablation (RFA) therapy.
- Trial name
- NCT07136324
- Testing
- EUS-guided RFA treatment
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- The University of Texas Health Science Center, Houston
Gall Stones, Gall Stones (& [Calculus - Gall Bladder])
A Study on the Efficacy and Safety of Endoscopic Ultrasound-guided Gastro-/Duodeno-cholecystostomy for the Treatment of Gallstones.
Gallstones, as a common benign gallbladder disease worldwide, have a prevalence of approximately 6.1%. Although laparoscopic cholecystectomy (LC) is currently the mainstream treatment, its associated complications cannot be…
- Trial name
- NCT07522385
- Testing
- cholecystolithotomy
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tongji Hospital
Liver Disease
A Randomized Controlled Trial Comparing Band Ligation and Cyanoacrylate Injection for Esophageal Varices
Compare VBL and cyanoacrylate injection (CI) in the treatment of EV in patients with advanced liver disease regarding eradication, bleeding, mortality, complication and recurrence rates.
- Trial name
- NCT00799851
- Testing
- Variceal band ligation, cyanoacrylate injection
- Where
- Brazil
- Volunteers
- 38 people
- Sponsor
- Federal University of São Paulo
Antro-pyloric and/or Duodenal Benign or Malignant Obstructions
Endoscopic Gastroenteric Anastomosis With New Tissue Apposing Stent in the Management of Antro-pyloroduodenal Obstruction : Evaluation of Feasibility, Efficacy and Tolerance.
Achieving gastro-jejunal or duodenal anastomosis (GJA ) by exclusive endoscopically is a real goal for many years in the development and research of the transluminal endoscopic surgery (N.O.T.E.S).
- Trial name
- NCT02562157
- Testing
- HYALURONIQUE ACIDE
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Cecostomy; Complications, Constipation
LAPEC for the Treatment of Severe Constipation
Effective treatment for constipation is a real clinical challenge especially in patients with severe symptoms. Dietary measures (bulking agents) and drugs (laxatives, stool softeners, suppositories and enemas etc.) have limited…
- Trial name
- NCT03909204
- Testing
- LAPEC
- Where
- Slovakia
- Volunteers
- 30 people
- Sponsor
- University Hospital Trnava
Rectal Neuroendocrine Tumors, ESD
Two Different Endoscopic Treatments for Rectal Neuroendocrine Neoplasms
The aim is to compare the safety and efficacy of endoscopic submucosal dissection (ESD) versus endoscopic partial muscle resection（ EPMR） for the treatment of rectal neuroendocrine neoplasms (R-NENs), thereby providing guidance…
- Conditions
- Rectal Neuroendocrine Tumors, ESD, EPMR
- Trial name
- NCT07612748
- Testing
- endoscopic intermuscular dissection (EID), Endoscopic Submucosal Dissection (ESD)
- Where
- 2 sites in China
- Volunteers
- 483 people
- Sponsor
- Jilin University
Portal Pressure Gradient (PPG) Measurement Guided by Endoscopic Ultrasound (EUS), Hepatic Cirrhosis
Evaluation of the Efficacy and Safety of Portal Pressure Gradient (PPG) Measurement Guided by Endoscopic Ultrasound (EUS) in the Therapeutic Algorithm of Patients with Liver Cirrhosis.
The development of Clinical significant PH (CSPH) is a major driver of complications. PPG is the strongest predictor of decompensation .
- Trial name
- GPP-USE (NCT06664307)
- Where
- Spain
- Volunteers
- 35 people
- Sponsor
- Hospital Universitario Virgen Macarena
Erectile Dysfunction, Lower Urinary Tract Symptoms
Efficacy of Tadalafil (5mg) For Treatment of Early Storage Symptoms and Erectile Dysfunction After Endoscopic Enucleation of Prostate
From previous studies, the investigators found that sexual outcomes after prostate surgery may show insignificant improvement, remain unchanged or deteriorate in non-negligible number of patients especially those with high…
- Trial name
- NCT05955001
- Where
- Egypt
- Volunteers
- 110 people
- Sponsor
- Mansoura University
Sarcoma,Soft Tissue, Nasal Cavity Cancer
Endoscopic Surgery in the Treatment of Soft Tissue Sarcoma in Nasal and Paranasal Sinus
Soft tissue sarcoma (STS) refers to a group of malignant tumors derived from non-epithelial extraosseous tissues, mainly from the mesoderm, partly from the neuroectoderm, including muscle, fat, fibrous tissue, blood vessels and…
- Conditions
- Sarcoma,Soft Tissue, Nasal Cavity Cancer, Paranasal Sinus Cancer, Surgery
- Trial name
- NCT05614375
- Testing
- endoscopic surgery
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Chronic Pain
Sedation in Endoscopic Retrograde Cholangiopancreatography (ERCP) With or Without Opioids
Addition of fentanyl or remifentanil to the propofol produced sedation for scheduled ERCP will decrease the propofol requirements for predetermined sedation levels (as shown by Bispectral Index Monitor (BIS) monitor), will be…
- Trial name
- NCT01304342
- Testing
- Remifentanil, Fentanyl, Normal saline
- Where
- Greece
- Volunteers
- 180 people
- Sponsor
- University of Athens
Intervention, Gastrointestinal Perforation
Purse String Suture Device vs. Endoclip for Immediate Endoscopic Procedure Associated Gastrointestinal Perforation
Nowadays, endoscopic techniques have been applied for diagnosing and treating a variety of gastrointestinal diseases, such as endoscopic submucosal dissection (ESD) and endoscopic mucosal resection (EMR)technique for removing…
- Trial name
- NCT03053232
- Testing
- Purse string suture device, Endoclips
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Affiliated Hospital to Academy of Military Medical Sciences
Colorectal Cancer
Endoscopic Optical Imaging for Precision Oncology Treatment Applied to Colorectal Tumours (Elios-Color-on-Specimen)
The Institute of Image-Guided Surgery (IHU) of Strasbourg is a translational research Institute aiming to develop hybrid surgery techniques.
- Trial name
- NCT04101292
- Testing
- Characterization of tumor tissue by fluorescence
- Sponsor
- IHU Strasbourg
Bleeding Peptic Ulcers
Hemostasis of Active Gastrointestinal (GI) Luminal Tract Bleeding
The objective of this study is to show that Hemospray is effective in achieving initial hemostasis and documenting rate of further bleed when compared to standard of care.
- Trial name
- HALT (NCT01306864)
- Testing
- Hemospray Kit
- Where
- 12 sites in Canada, Hong Kong and 2 more
- Volunteers
- 67 people
- Sponsor
- Cook Group Incorporated
Pancreatic Cancer, Pancreatic Duct Stricture
Palliative Pancreatic Duct Stenting in Patients With Inoperable Pancreatic Cancer
Patients with pancreatic cancer often suffer from chronic abdominal pain, weight loss and decreased quality of life. The patients also often need pancreatic enzyme supplements.
- Trial name
- NCT03069664
- Testing
- ERCP, Covered Self-expandable Metal Stent
- Where
- 2 sites in Finland
- Volunteers
- 40 people
- Sponsor
- Helsinki University Central Hospital
Recurrent Nasopharyngeal Carcinoma
Neoadjuvant vs Adjuvant in Locally Advanced Recurrent NPC
A multicenter randomized controlled study of surgery combined with neoadjuvant and adjuvant therapy for locally advanced recurrent nasopharyngeal carcinoma in comparison to surgery combined with adjuvant therapy
- Trial name
- NCT06235203
- Testing
- endoscopic surgery, Neoadjuvant therapy,Toripalimab Injection and Gemcitabine based therapy, Adjuvant therapy in experimental group,Toripalimab Injection and Gemcitabine based therapy
- Where
- 7 sites in China
- Volunteers
- 154 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Biliary Disease, Pancreatic Diseases
Calgary Registry for Advanced and Therapeutic Endoscopy
The aim of the Calgary Registry for Advanced and Therapeutic Endoscopy (CReATE) is to be a high-fidelity prospective multi-centre registry.
- Trial name
- CReATE (NCT04259580)
- Testing
- Endoscopic retrograde pancreatography (ERCP)
- Where
- Canada
- Volunteers
- 6,000 people
- Sponsor
- University of Calgary
Portal Hypertension, Liver Cirrhosis
Efficacy and Safety of EUS-Guided Therapy Versus BRTO for Gastric Varices With Shunt
This study is a retrospective, multi-center and observational clinical study. Renmin Hospital of Wuhan University, Beijing Friendship Hospital, Capital Medical University, The fifth medical center of PLA General Hospital…
- Conditions
- Portal Hypertension, Liver Cirrhosis, Gastric Varix, Portosystemic Shunt
- Trial name
- NCT04828369
- Testing
- EUS-guided coil embolization combined with endoscopic cyanoacrylate injection, balloon-occluded retrograde transvenous obliteration
- Where
- China
- Volunteers
- 104 people
- Sponsor
- Renmin Hospital of Wuhan University
Obesity
Benefits of Endoscopic Bariatric Procedures
This 12-months long pilot study will include patients undergoing an endoscopic procedure (endoscopic sleeve gastroplasty [ESG] or transoral outlet reduction [TORe]) as clinically indicated, and subsequent follow up clinic visits…
- Trial name
- NCT05514288
- Testing
- Endobariatric procedure
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center