Clinical trials: Therapeutic Engagement
Mental Health, Suicide
Public Messaging to Increase Treatment Seeking for Veterans at Risk for Suicide
The risk for suicide increases by nearly 50% in the first year that service members transition from the military to civilian life underscoring the need for effective strategies to facilitate help seeking among Veterans vulnerable…
- Trial name
- NCT04784663
- Testing
- Messaging, Wait list control
- Where
- United States
- Volunteers
- 355 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Diabetes (Insulin-requiring, Type 1 or Type 2), Pediatric Diabetes
A Novel Miniature Equine-Assisted Diabetes Education Program for Youth: Evaluating the Diabetes Equine Empowerment Program (DEEP).
The Diabetes \& Equine Empowerment Program (DEEP) is a research study evaluating a novel diabetes education program that combines hands-on interactions with miniature horses and evidence-based diabetes self-management education…
- Conditions
- Diabetes (Insulin-requiring, Type 1 or Type 2), Pediatric Diabetes, Diabetes (DM)
- Trial name
- DEEP (NCT07822555)
- Testing
- Diabetes & Equine Empowerment Program (DEEP)
- Volunteers
- 50 people
- Sponsor
- Nemours Children's Clinic
Inflammatory Bowel Diseases, Crohn Disease
Patient Automated Text Hovering for IBD
This is a 2-arm randomized trial aimed at leveraging behavioral science principles to improve patient engagement between office visits among patients with inflammatory bowel disease (IBD).
- Conditions
- Inflammatory Bowel Diseases, Crohn Disease, Ulcerative Colitis
- Trial name
- PATH-IBD (NCT04388865)
- Testing
- Control, Text-based Clinical Hovering
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Pennsylvania
Experience, Life, Dialysis
What Does the Patient Experience Represent for Patients and Caregivers in Dialysis?
The primary objective of this work is to describe the vision, representations, and beliefs of professionals and patients regarding the role and place of the user during their care journey at the Calydial renal health facility.
- Conditions
- Experience, Life, Dialysis, Patient Engagement, Patient Participation
- Trial name
- EnquêteXP (NCT06529887)
- Where
- 4 sites in France
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Calydial
Breast Cancer, Breast Cancer Female
Abbreviated MBCT for Depression in Older Black or African American Breast Cancer Survivors
The purpose of this research study is to develop and test an intervention designed to improve mood and reduce symptoms of depression.
- Conditions
- Breast Cancer, Breast Cancer Female, Breast Cancer Stage I, Breast Cancer Stage II
- Trial name
- NCT06336538
- Testing
- MBCT
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Case Comprehensive Cancer Center
Alcohol Use Disorder
Virtual Reality (VR) NATURE - Alcohol Use Disorder (AUD)
This pilot randomized clinical trial will evaluate the feasibility, acceptability, and preliminary effectiveness of immersive Virtual Reality (VR) nature intervention among adults with at least moderate depression symptoms…
- Trial name
- NCT07413458
- Testing
- Virtual Reality (VR) -nature treatment, Survey completion
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Michigan
Hepatitis C, Substance Use Disorders
Hepatitis C Treatment in PWIDs: MAT or Syringe Exchange Assisted-therapy vs Standard of Care
hepatitis C virus (HCV) has traditionally been treated in subspecialty health centers given the complexity of older pegylated interferon containing regimens, formerly the standard of care.
- Conditions
- Hepatitis C, Substance Use Disorders, Substance Abuse, Intravenous
- Trial name
- NCT03093415
- Testing
- elbasvir-grazoprevir (50 mg/100 mg)
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Oregon Health and Science University
Hiv, AIDS
ALHIV Smartphone Game Study
This is a cluster-randomized controlled trial that aims to conduct comprehensive feasibility testing of a smartphone game in a sample of 120 adolescents living with HIV (ALHIV) ages 15-21 in Kisumu, Kenya, to determine whether…
- Conditions
- Hiv, AIDS, Adolescent Behavior, Treatment Compliance
- Trial name
- NCT06913660
- Testing
- MyGoals, Standard of care
- Where
- Kenya
- Volunteers
- 120 people
- Sponsor
- Emory University
Metastatic Cancer, Locally Advanced Cancer
An Intervention to Help Patients and Caregivers Manage Stress and Improve Communication Skills When Talking About Cancer
This study will test an intervention to improve patients' and their caregivers' ability to manage difficult emotions and communicate about the patient's illness.
- Conditions
- Metastatic Cancer, Locally Advanced Cancer, Thoracic Cancer, Gynecologic Cancer
- Trial name
- NCT03794635
- Testing
- Weekly 45 minute Sessions
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Patient Engagement, Behavioral Symptoms
How to Bathe a Person With Dementia? A Bathing Intervention Based on Basale Stimulation® for People With Moderate to Severe Dementia
Brief summary Resisted behaviours that occur during showering of People with Dementia (PwD) cause greater discomfort for caregivers and may occur as a result of embarrassment and shame that the person with dementia may be…
- Trial name
- NCT05353049
- Testing
- Bathing technique based on Basale Stimulation
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- University of Salamanca
Gastro Intestinal Bleeding, Patient Engagement
Patient Important Gastrointestinal Bleeding in the ICU
This study will engage patients and families to create a definition of what matters most to them about upper gastrointestinal (GI) bleeding.
- Conditions
- Gastro Intestinal Bleeding, Patient Engagement, Family Members
- Trial name
- PIB (NCT05506150)
- Testing
- Interviews
- Where
- Canada
- Volunteers
- 51 people
- Sponsor
- McMaster University
HIV, Depression
Enhanced Problem-solving Therapy and HIV Engagement Support to Improve Perinatal Mental Health & HIV Outcomes in Malawi
The main objective of the proposed study is to evaluate the effectiveness of the Enhanced Friendship Bench intervention to improve perinatal depression, HIV care engagement, and infant health outcomes among pregnant women with…
- Conditions
- HIV, Depression, Depression, Postpartum
- Trial name
- NCT06702722
- Testing
- Enhanced Friendship Bench, Enhanced usual care
- Where
- 5 sites in Malawi
- Volunteers
- 400 people
- Sponsor
- University of North Carolina, Chapel Hill
Stroke
At Home Wearable Sensors and Smartphone for Stroke Survivors With Upper Limb Motor Challenges.
The goal of this clinical trial is to learn if wearable sensor data visualization on smartphones can improve the use of the stroke-affected limb during everyday activities.
- Trial name
- NCT06787729
- Testing
- mHealth
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Spaulding Rehabilitation Hospital
Chronic Pain, Veterans
Co-Adaptation of an Digital Pain Management Program for Canadian Veterans
The goal of this study is to gather feedback from Canadian Veterans living with chronic pain, and clinicians serving Canadian Veterans, on an existing digital psychology program for self-management of chronic pain delivered…
- Trial name
- ADOPTCanVets (NCT07818980)
- Testing
- Self-Guided Digital Acceptance and Commitment Therapy Program
- Where
- Canada
- Volunteers
- 22 people
- Sponsor
- University Health Network, Toronto
Opioid Use Disorder
PEERS Pilot: Peer Recovery Support Program to Support Engagement in Medication for Opioid Use Disorder
The goal of this pilot study is to evaluate the feasibility and acceptability of implementing a peer recovery support program to support patient engagement in medication treatment for opioid use disorder (MOUD).
- Trial name
- PEERS (NCT06696066)
- Testing
- PRS Program
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Geisinger Clinic
Opioid-use Disorder
A Remote, Decentralized Opioid Use Disorder Study to Evaluate Patient Engagement With a Game-Based Digital Therapeutic
The purpose of this study is to evaluate how patients use and engage with a game-based mobile application that is designed to treat opioid use disorder.
- Trial name
- NCT04542642
- Testing
- reSET-O, PEAR-008
- Where
- 2 sites in United States
- Volunteers
- 52 people
- Sponsor
- Pear Therapeutics, Inc.
Cardiac Disease, Risk Factor, Cardiovascular
Virtual Reality Based-therapy Applied to Physical Therapy in Cardiology.
The aim of this study is to investigate engagement, motivation, and the barriers to adherence of virtual reality based therapy (VRBT) in patients with cardiac diseases and risk factors to the development of cardiac diseases.
- Trial name
- NCT03377582
- Testing
- Exercise
- Where
- Brazil
- Volunteers
- 68 people
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
COVID-19, Vaccine Refusal
CATCH-UP Vaccines: Engaged Approaches to Testing in Community/Healthcare Settings for the Underserved (COVID-19)
Oklahoma has high COVID-19 incidence, particularly among underserved minority and rural Oklahomans. Oklahoman's are also reporting SARS-CoV-2 vaccine hesitancy and signs of slowing vaccine uptake, with increased hesitancy among…
- Trial name
- NCT05236270
- Testing
- Text Message, Motivational Interviewing, Electronic Educational Message with Tailored Questions/Prompts
- Where
- United States
- Volunteers
- 312 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Patient Participation
Electronic Health Record Strategies to Promote Diverse Participation in Research
The purpose of this study is to determine the effectiveness of enhanced features in an online patient portal including banners, a chatbot, and direct to patient message and traditional mailed letters on increasing interest in…
- Trial name
- NCT05348603
- Testing
- Traditional Letter, Direct to Patient Message, Chatbot
- Where
- United States
- Volunteers
- 726,199 people, healthy volunteers welcome
- Sponsor
- Yale University
HIV Treatment
Building Rapid Inpatient Delivery of ART to Generate Engagement in HIV Care
The study team will pilot rapid antiretroviral therapy (ART) initiation as part of routine inpatient care at the University of Chicago Medicine (UCM), comparing outcomes over a 12-month implementation period.
- Trial name
- BRIDGE (NCT07847567)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Chicago