Clinical trials: Therapeutic Engagement
Suicidal Ideation, Treatment Engagement
Motivational Interviewing to Prevent Suicide in High Risk Veterans
The purpose of study is to test the efficacy of an adaptation of Motivational Interviewing to Address Suicidal Ideation (MI-SI) on the severity of suicidal ideation in psychiatrically hospitalized Veterans at high risk for…
- Trial name
- NCT01544127
- Testing
- MI-SI+TAU, MI-SI-R+TAU, TAU Alone
- Where
- United States
- Volunteers
- 132 people
- Sponsor
- VA Office of Research and Development
Chronic Fatigue Syndrome, Myalgic Encephalomyelitis
Assessment of N-Acetylcysteine as Therapy for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
Chronic fatigue syndrome/myalgic encephalomyelitis (ME/CFS) is an unexplained multisymptom/multisystem disorder for which there are currently no validated treatments.
- Trial name
- NAC ME/CFS (NCT04542161)
- Testing
- NAC 900mg/day, NAC 3600mg/day
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- Weill Medical College of Cornell University
Smoking Cessation
Increasing Digital Equity and Access Among Rural Patients (IDEA) Study
The purpose of this research is to learn more about how access to digital resources impacts healthcare and smoking cessation in rural areas of Minnesota, Iowa, and Wisconsin.
- Trial name
- NCT05209451
- Testing
- Digital, evidence-based behavioral health program for smoking cessation, Bluetooth enabled iPad, Coaching Support
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Mayo Clinic
Opioid Use Disorder, Intimate Partner Violence (IPV)
Project STRONGER: Stepped Care for Opioid Use Disorder Treatment Engagement and Recovery
Using a hybrid type 1 effectiveness-implementation approach, this study aims to evaluate the impact of a novel stepped care model ("PCT+2HOPE") versus treatment as usual (TAU) on increasing retention in community-based medication…
- Conditions
- Opioid Use Disorder, Intimate Partner Violence (IPV), Post Traumatic Stress Disorder PTSD
- Trial name
- STRONGER (NCT07115030)
- Testing
- PCT+2HOPE
- Where
- 3 sites in United States
- Volunteers
- 532 people
- Sponsor
- Yale University
Chronic Kidney Diseases
Kidney AI-enabled Care Transformation
In the Kidney ACTion study, CKD (Chronic Kidney Disease) patients at increased risk of progression to ESRD (End Stage Renal Disease) will be randomly assigned to either standard of care in a specialist nephrology outpatient…
- Trial name
- NCT05056909
- Testing
- Kidney ACTion, Standard of care
- Where
- 2 sites in Italy, United Kingdom
- Sponsor
- Medical University of Graz
Alcohol Use Disorder
Virtual Reality (VR) NATURE - Alcohol Use Disorder (AUD)
This pilot randomized clinical trial will evaluate the feasibility, acceptability, and preliminary effectiveness of immersive Virtual Reality (VR) nature intervention among adults with at least moderate depression symptoms…
- Trial name
- NCT07413458
- Testing
- Virtual Reality (VR) -nature treatment, Survey completion
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Michigan
Chronic Pain, Opioid Use Disorder
Pain Self-Management and Treatment Engagement for Patients Taking Opioids
The goal of this study is to learn if Pain Self-Management (PSM) can improve chronic pain care in individuals with opioid misuse or opioid use disorder (OUD) The main questions it aims to answer are: Does PSM help participants…
- Conditions
- Chronic Pain, Opioid Use Disorder, Opioid Misuse and Addiction
- Trial name
- TREETOP (NCT06855732)
- Testing
- Usual Care, Pain Self-Management
- Where
- 17 sites in United States
- Volunteers
- 204 people
- Sponsor
- University of Pittsburgh
Pain, Sickle Cell Disease
Peer Support for Adolescents and Emerging Adults With Sickle Cell Pain
The study, known as the Peer suppoRt for adolescents and Emerging adults with Sickle cell pain: promoting ENgagement in Cognitive behavioral thErapy (PRESENCE), aims to determine the effectiveness of digital CBT in reducing pain…
- Trial name
- PRESENCE (NCT06374238)
- Testing
- CBT+ Health coach, CBT w/o Health Coach ( self-guided), Usual Care
- Where
- 14 sites in United States
- Volunteers
- 390 people
- Sponsor
- University of Pittsburgh
PTSD, Posttraumatic Stress Disorder
The Use of a Novel Peer Education Program for Improving PTSD Treatment Engagement Among Veterans
Behavioral health problems among Veterans have raised awareness of the critical need for more reliable, effective, and accessible ways to recognize those in need, direct them to help, and ensure that they receive the best…
- Trial name
- AboutFace (NCT03521999)
- Testing
- AboutFace, Enhanced Usual Care (eUC)
- Where
- United States
- Volunteers
- 330 people
- Sponsor
- VA Office of Research and Development
Post Traumatic Stress Disorder
Stepped Care for Posttraumatic Stress Disorder Study
Less than 20% of people with PTSD receive any treatment. This study extends a program of research by the investigator focused on developing adaptive (stepped) interventions for PTSD.
- Trial name
- STEPPS (NCT06947538)
- Testing
- webSTAIR, WebSTAIR plus coaching, Clinician administered Brief STAIR
- Where
- United States
- Volunteers
- 428 people
- Sponsor
- Boston Medical Center
Patient Satisfaction, Patient Engagement
Patient Centered Care in Diabetes in Ecuador
Introduction: According to World Health Organization data, it is estimated that more than 422 million people have diabetes. In Ecuador, diabetes is the second cause of death, only after ischemic heart disease, and is the first…
- Conditions
- Patient Satisfaction, Patient Engagement, Patient Empowerment, Health Literacy
- Trial name
- NCT04592263
- Testing
- EPD Questionnaire
- Where
- 3 sites in Ecuador, Spain
- Volunteers
- 524 people
- Sponsor
- Universidad Miguel Hernandez de Elche
Substance Abuse
Brief Interventions for Drop-out Re-engagement
We will evaluate a series of interventions intended to help individuals who drop out of substance abuse treatment re-engage in order to improve treatment outcome.
- Trial name
- NCT00350571
- Testing
- brief (behavioral therapy), Drop out re-engagement motivational intervention, standard care follow up
- Where
- 2 sites in United States
- Volunteers
- 299 people
- Sponsor
- Yale University
HIV Treatment
Building Rapid Inpatient Delivery of ART to Generate Engagement in HIV Care
The study team will pilot rapid antiretroviral therapy (ART) initiation as part of routine inpatient care at the University of Chicago Medicine (UCM), comparing outcomes over a 12-month implementation period.
- Trial name
- BRIDGE (NCT07847567)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Chicago
Patient Engagement
Virtual and Video Counseling Versus In-Office Counseling for Laparoscopic Hysterectomy
Compare preparedness for total laparoscopic hysterectomies between patients who undergo virtual visits and those who undergo in-office visits for pre-operative counseling.
- Trial name
- NCT05086406
- Testing
- Combination of Video and Virtual Pre-operative Counseling
- Where
- United States
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Patient Engagement, Femoral Angiography
Use of Back Support After Transfemoral Angiography
In the routine treatment procedure after coronary angiography (CAG), the patients remain in the supine position for a long time, which leads to decreased venous return and back pain.
- Trial name
- NCT06643182
- Testing
- Back Support
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Inonu University
Decision Making, Computer-assisted
Diagnosis Assessment With Diaana #3
Single-center, unblinded, 2:1 parallel pseudo-randomized efficacy trial. In the intervention group only, resident physicians will be assisted by the automated medical history-taking device "Diaana" during their consultations in…
- Conditions
- Decision Making, Computer-assisted, General Practitioners, Patient Engagement
- Trial name
- NCT03939650
- Testing
- Diaana
- Where
- Switzerland
- Sponsor
- Adrien Schwitzguebel
Lung Cancer
Tribally Engaged Approaches to Lung Screening (TEALS)
Lung cancer is the leading cause of cancer mortality among American Indians and Alaska Natives (AI/AN), and AI/AN have worse lung cancer incidence rates, survival, and death compared to the general population.
- Trial name
- TEALS (NCT04948060)
- Testing
- Enhanced lung cancer screening services
- Where
- United States
- Volunteers
- 275 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Hypertension
Medication Adherence Improvement Support App For Engagement - Blood Pressure
The purpose of this study is to evaluate the impact of the Medisafe smartphone application on blood pressure control and self-reported medication adherence for patients with uncontrolled blood pressure.
- Trial name
- MedISAFE-BP (NCT02727543)
- Testing
- Medisafe
- Where
- United States
- Volunteers
- 413 people
- Sponsor
- Brigham and Women's Hospital
Depression, Anxiety, Psychological Trauma
Internet-Delivered Cognitive Behaviour Therapy for Public Safety Personnel
This study evaluates a transdiagnostic Internet-delivered cognitive behavioural therapy (ICBT) recently tailored for Canadian public safety personnel (PSP) reporting symptoms of depression, anxiety, or posttraumatic stress.
- Trial name
- NCT04127032
- Testing
- PSP Wellbeing Course
- Where
- Canada
- Volunteers
- 250 people
- Sponsor
- University of Regina
Opioid-use Disorder, Acceptability of Health Care
Patients' Attitudes Toward and Experiences With Buprenorphine Treatment
This study will disseminate five surveys collecting individual's attitudes and experiences during buprenorphine treatment for Opioid Use Disorder during the COVID-19 pandemic.
- Conditions
- Opioid-use Disorder, Acceptability of Health Care, Opioid-Related Disorders
- Trial name
- NCT05121428
- Where
- United States
- Volunteers
- 817 people, healthy volunteers welcome
- Sponsor
- Cambridge Health Alliance