Clinical trials: Therapeutic Engagement
Inflammatory Bowel Disease (Crohn's Disease; Ulcerative Colitis), Adherence, Patient
Treatment Adherence Among Patients With Inflammatory Bowel Disease Receiving Anti-TNF Therapy
Inflammatory bowel disease (IBD) is a chronic condition characterized by periods of remission and relapse, requiring long-term treatment adherence to maintain disease control and prevent complications.
- Conditions
- Inflammatory Bowel Disease (Crohn's Disease; Ulcerative Colitis), Adherence, Patient, Structured Education
- Trial name
- NCT07652840
- Testing
- Health Belief Model-Based Structured Patient Education, Standard Patient Education
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Izmir Katip Celebi University
Stress
Interoceptive Engagement
The proposed project is the first pilot test to examine interoceptive function as a mechanistic biomarker underlying Mindful Awareness in Body-oriented Therapy (MABT).
- Trial name
- NCT03583060
- Testing
- Mindful Awareness in body-oriented therapy
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Washington
Cystic Fibrosis (CF)
Effectiveness of Gamified Mobile Health Apps for Airway Clearance Therapy in Children and Adolescents With Cystic Fibrosis
The aim of this randomized controlled trial is to evaluate the effectiveness of gamified mobile health (mHealth) applications for airway clearance therapy in children and adolescents with cystic fibrosis.
- Trial name
- EGmACT-CF (NCT06958094)
- Testing
- Gamified mobile health applications, Conventional Airway Clearance Therapy, Combination Treatment
- Where
- Spain
- Volunteers
- 36 people
- Sponsor
- Universidad de Córdoba
Vascular Diseases, Patient Empowerment
PREMs In Vascular SurgERy Enhancement Study
THE PROBLEM: Patient Reported Experience Measures (PREMs) ask patients about their healthcare service experience. It gives them a voice to share their views.
- Conditions
- Vascular Diseases, Patient Empowerment, Patient Satisfaction, Patient Engagement
- Trial name
- PREMIERE (NCT06363175)
- Where
- United Kingdom
- Volunteers
- 330 people
- Sponsor
- Cardiff and Vale University Health Board
Atrial Fibrillation (AF), Cardiovascular Diseases
Empowering Veterans in Research Effectively Using Virtual Engagement Tools
Cardiovascular disease is the leading cause of death among Veterans. Clinical trials are essential for developing better treatments, but Veterans remain underrepresented in these studies due to barriers including limited health…
- Trial name
- EVERYVET (NCT07741955)
- Testing
- AI-Generated Avatar Videos for Clinical Trial Outreach
- Where
- United States
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Patient Engagement, End of Life
Advance Care Planning for Older Latinos With Chronic Illness
The goal of this study is to test the feasibility of a randomized controlled trial to learn about implementation of an intervention model, Advance Care Planning I Plan (ACP-I Plan), among older Latinos with chronic illnesses in…
- Conditions
- Patient Engagement, End of Life, Chronic Disease, Communication
- Trial name
- NCT06081660
- Testing
- ACP-I Plan
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- San Diego State University
Chronic Pain
Optimizing Patient Engagement in a Novel Pain Management Initiative (OPEN)
The OPEN study has two aims: The first is to identify what helps to keep patients involved with a Medicaid chronic pain management program and to identify features of an ideal text-message-based program for people enrolled in the…
- Trial name
- OPENtext (NCT02136108)
- Testing
- OPENtext, OPENnav
- Where
- United States
- Volunteers
- 197 people
- Sponsor
- Inflexxion, Inc.
Opioid Use Disorder, Chronic Pain
Healing Opioid Misuse and Pain Through Engagement (HOPE) Trial
This study is a multisite randomized clinical trial of a treatment designed to reduce pain interference while simultaneously addressing relapse prevention among individuals who have co-occurring chronic pain and Opioid Use…
- Trial name
- HOPE (NCT05571917)
- Testing
- Acceptance and Commitment Therapy + Mindfulness Based Relapse Prevention (ACT + MBRP), Enhance Usual Care (EUC)
- Where
- 2 sites in United States
- Volunteers
- 160 people
- Sponsor
- University of New Mexico
HIV Infections, Tuberculosis
South Africa Smoking Cessation and Engagement in HIV/TB Care Care
The purpose of this study is to integrate elements from existing interventions developed by our team into a single intervention (QUIT-AD), designed to improve smoking cessation and favorable HIV/TB treatment outcomes among…
- Conditions
- HIV Infections, Tuberculosis, Smoking Cessation
- Trial name
- NCT05842161
- Testing
- QUIT-AD, Enhanced Treatment as Usual
- Where
- South Africa
- Volunteers
- 83 people
- Sponsor
- Massachusetts General Hospital
Recreational Drug Use
Chemsex Engagement and HIV Biomedical Prevention in MSM
HIV biomedical prevention through treatment-as-prevention (TasP) and pre-exposure prophylaxis (PrEP) is highly efficacious for reducing HIV transmission risk.
- Trial name
- NCT05031832
- Testing
- HIV test
- Where
- Hong Kong
- Volunteers
- 733 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Orthodontic Extraction, Orthodontic Treatment
A Comparative Assessment of Post Extraction Pain in Orthodontic Patients to Evaluate the Effects of Early Engagement of Tooth with Orthodontic Wires. a Single Center Randomized Clinical Trial (RCT)
The goal of this clinical trial is to determine if the timing of tooth extractions (before or after initial orthodontic treatment) affects pain levels in patients who need bilateral extractions of first premolars in the upper…
- Conditions
- Orthodontic Extraction, Orthodontic Treatment, Orthodontic Treatment Via Premolar Extraction
- Trial name
- NCT06582836
- Testing
- The objective of the study was to investigate the effect of prior engagement of tooth with orthodontic appliance on post extraction pain among orthodontic patients
- Where
- Pakistan
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Cardiovascular Diseases
Virtual Reality-based Therapy and Barriers in Cardiac Patients
The aim of this study is to investigate the chronic hemodynamic and autonomic repercussions of the insertion of VRBT in CR. To qualitatively analyze the perception of patients and physiotherapists regarding the use of VRBT, as…
- Trial name
- NCT04336306
- Testing
- virtual reality-based therapy (VRBT)
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho
Physiological Conditions, Distress, Emotional
Hand in Hand: Feasibility of a Compassion-Focused App to Support Parents of Children With Mental Health Problems
Parents of children and adolescents with mental health problems may experience substantial caregiving burden and emotional distress, including persistent stress, self-criticism, shame, and parental burnout.
- Conditions
- Physiological Conditions, Distress, Emotional, Caregiving Stress, Burnout
- Trial name
- NCT07840404
- Testing
- App-based Compassion Program
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Stroke, Non-communicable Disease
Make My Day - a Stroke Prevention Program
The purpose of this study is to evaluate the effects of a person-centered stroke prevention program implemented in primary healthcare.
- Trial name
- NCT05279508
- Testing
- Make My Day - stroke prevention program
- Where
- Sweden
- Volunteers
- 122 people
- Sponsor
- Karolinska Institutet
Mental Health Crisis
Intervention to Increase Treatment Engagement Among Individuals Referred for Post-Crisis Mental Health Services
This study will evaluate the preliminary effectiveness of Make It!, a single 15-minute intervention aimed at increasing attendance to a follow-up appointment for psychological services (i.e., an information class) among clients…
- Trial name
- NCT02904746
- Testing
- Make It!
- Where
- Canada
- Sponsor
- University of Manitoba
Genital Herpes, Patient Engagement
A Study of the Characteristics of Patients Diagnosed With Recurrent Symptomatic Genital Herpetic Disease
Determine the baseline characteristics of patients who have recurrent symptomatic genital herpetic disease Determine the acceptance to patients of clinical trial procedures Determine interest in participation in genital herpes…
- Trial name
- NCT05500053
- Where
- United Kingdom
- Volunteers
- 68 people
- Sponsor
- Rational Vaccines Inc
Smoking, Smoking Cessation
Hollings Cancer Center Varenicline Sampling Study
The purpose of this study is to learn what happens when people are given a free, 4-week, sample of varenicline, a smoking cessation medication.
- Conditions
- Smoking, Smoking Cessation, Smoking, Tobacco, Smoking, Cigarette
- Trial name
- NCT03742154
- Testing
- Varenicline 0.5 MG
- Where
- United States
- Volunteers
- 99 people
- Sponsor
- Medical University of South Carolina
Kidney Replacement Therapy
Community Health Workers in an Interdisciplinary Outpatient CKD Clinic to Optimize Social Care Navigation, Patient Engagement, and Home Dialysis Utilization
The goal of this clinical trial is to learn if this intervention (the CHOOSE Home intervention) is feasible and may lead to more home dialysis usage in a high-risk patient population.
- Trial name
- CHOOSE Home (NCT06925776)
- Testing
- CHOOSE Home Intervention, Usual Care
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- Montefiore Medical Center
Opioid Dependence, Opioid Abuse
A Pragmatic Trial of the Consult for Addiction Treatment and Care in Hospitals (CATCH) Model for Engaging Patients in Opioid Use Disorder Treatment
This pragmatic clinical trial seeks to evaluate the effectiveness of the Consult for Addiction Treatment and Care in Hospitals (CATCH) intervention as a strategy for engaging patients with Opiod Use Disorder (OUD) in addiction…
- Trial name
- CATCH (NCT03611335)
- Testing
- CATCH Interviews
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- NYU Langone Health
Decision Making, Computer-assisted
Diagnosis Assessment With Diaana #3
Single-center, unblinded, 2:1 parallel pseudo-randomized efficacy trial. In the intervention group only, resident physicians will be assisted by the automated medical history-taking device "Diaana" during their consultations in…
- Conditions
- Decision Making, Computer-assisted, General Practitioners, Patient Engagement
- Trial name
- NCT03939650
- Testing
- Diaana
- Where
- Switzerland
- Sponsor
- Adrien Schwitzguebel