Clinical trials: Therapeutic Engagement
Opioid Use Disorder
Mobile Mindfulness Training (mMT) for People in Medication Treatment of Opioid Use Disorder (MOUD)
The goal of this clinical trial is to learn if mobile mindfulness training can help people in treatment for opioid use disorder.
- Trial name
- NCT06857968
- Testing
- Mobile Mindfulness Training
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Amy Meadows
Schizophrenia, Schizoaffective Disorder
Shared Decision Making for Antipsychotic Medications
This study aims to provide an evidence-based shared decision making intervention for antipsychotic medications, the Antipsychotic Medication Decision Aid (APM-DA), for individuals experiencing early psychosis and provide, for the…
- Conditions
- Schizophrenia, Schizoaffective Disorder, Schizophreniform Disorders, Delusional Disorder
- Trial name
- NCT05416658
- Testing
- The Antipsychotic Medication Decision Aid (APM-DA)
- Volunteers
- 120 people
- Sponsor
- New York State Psychiatric Institute
Anxiety
Brief Anxiety Skills Training Intervention for Veterans in Primary Care
Anxiety symptoms are common among primary care patients, but anxiety is undertreated. Brief behavioral (non-medication) anxiety treatments are needed.
- Trial name
- NCT04829240
- Testing
- Veterans Anxiety Skills Training Intervention, PCMHI Usual Care
- Where
- 2 sites in United States
- Volunteers
- 213 people
- Sponsor
- VA Office of Research and Development
Cancer
Engaging M-health for Symptom Monitoring and Health Promotion for Women on Endocrine Therapy for Breast Cancer (EmSHAPE)
The purpose of the study is to learn more about ways to help patients understand and manage side-effects from hormone therapy. The investigators will use the information from this study to design future studies to better…
- Trial name
- NCT07454499
- Testing
- Digital Endocrine therapy Symptom Monitoring and Education Intervention
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Post-Acute Sequelae of SARS-CoV-2 Infection, Long COVID
Observational Study of Intranasal IVIG in Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Patients Undergoing Medical Tourism
This observational study is being conducted by Healing Hope International to collect real-world data on an emerging treatment approach for Long COVID in patients with immunodeficiency.
- Conditions
- Post-Acute Sequelae of SARS-CoV-2 Infection, Long COVID, Long COVID Fatigue, Long COVID Syndrome
- Trial name
- IVIG-LC (NCT06992401)
- Volunteers
- 50 people
- Sponsor
- Tamara C Tamas
Acute Lymphoblastic Leukemia, Pediatric, Pediatric Cancer
Biology and Benefits of Music Play and Stories for Kids/Parents During ALL Treatment
Music therapy has become a standard palliative care service in many pediatric and adult hospitals; however, a majority of music therapy research has focused on the use of music to improve psychosocial dimensions of health…
- Trial name
- NCT04400071
- Testing
- Active Music Engagement, Audio Storybooks
- Where
- 4 sites in United States
- Volunteers
- 192 people
- Sponsor
- Indiana University
Alzheimer Disease
Study to Assess the Safety and Biological Activity of AMX0035 for the Treatment of Alzheimer's Disease
The study is a 24-week, randomized, double-blind, multi-site, placebo-controlled study in participants with mild cognitive impairment (MCI) or early dementia due to Alzheimer's disease (AD).
- Trial name
- PEGASUS (NCT03533257)
- Testing
- AMX0035
- Where
- 11 sites in United States
- Volunteers
- 95 people
- Sponsor
- Amylyx Pharmaceuticals Inc.
Obesity
The EMBER Trial for Weight Management Engagement
This study will test whether EMBER, a self-help tool to increase weight loss treatment engagement, helps veterans engage in Veterans Health Administration (VHA) weight management programs.
- Trial name
- NCT05424081
- Testing
- EMBER, Control
- Where
- 2 sites in United States
- Volunteers
- 470 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Opioid Use Disorder, Moderate, Opioid Use Disorder, Severe
A Brief Negotiation Interview Chatbot to Improve Buprenorphine Engagement Among Justice-Involved Individuals
Primary Objective: Conduct pilot study to assess effects of brief negotiation interview (BNI) Chatbot among individuals involved in the Connecticut criminal justice system with opioid use disorder (OUD).
- Conditions
- Opioid Use Disorder, Moderate, Opioid Use Disorder, Severe, Criminal Behavior
- Trial name
- BNICHAT (NCT04982627)
- Testing
- BNI Chatbot, OUD Education & Treatment Resources
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Center for Progressive Recovery, LLC
IBM, IIM
MIHRA - Patient-Rooted Insights for Shaping Myositis Science (PRISMS)
Myositis diseases are each rare diseases. As in other rare diseases, people living with myositis diseases face physical and psychosocial challenges that may not be recognized in current research priorities.
- Conditions
- IBM, IIM, Myositis, Inflammatory Myopathy
- Trial name
- MIHRA-PRISMS (NCT07374107)
- Testing
- No intervention - qualitative and mixed methods investigations
- Where
- United States
- Volunteers
- 700 people
- Sponsor
- Myositis International Health & Research Collaborative Alliance Foundation
Preterm Birth, Prematurity
Parent-child Interactions, Child Developmental Health, and Health System Costs at 6 Months Corrected Age
The aim of this novel health services research proposal is to assess the longer-term outcomes, to 6 months corrected age, of an adapted Family Integrated Care (FICare) model of care for moderate and late preterm infants admitted…
- Conditions
- Preterm Birth, Prematurity, Infant,Premature, Infant Development
- Trial name
- NCT03357458
- Testing
- Family Integrated Care
- Where
- Canada
- Volunteers
- 56 people
- Sponsor
- University of Calgary
Substance-Related Disorders, Treatment Adherence
Motivational Interviewing at Intake vs Intake as Usual on Client Engagement in Addiction Treatment
This K23 study is an effectiveness-implementation hybrid type I design to determine the effectiveness of Motivational Interviewing at Intake (MII), relative to intake-as-usual on client engagement and mechanisms of engagement…
- Trial name
- NCT05489068
- Testing
- Motivational Interviewing at Intake (MII), Intake as Usual (IAU)
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of New Mexico
Health Knowledge, Attitudes, Practice, Vaccine-Preventable Diseases
Culturally Tailored HPV Psychoeducational Multimedia Intervention
Community members ages 18 - 45 years old from the El Paso, Texas, U.S.-Mexico Border Region will be recruited to compare psychoeducational multimedia interventions focused on the human papillomavirus (HPV).
- Conditions
- Health Knowledge, Attitudes, Practice, Vaccine-Preventable Diseases, Intention, Adherence, Patient
- Trial name
- NCT06098690
- Testing
- Culturally Tailored Multimedia Psychoeducational HPV Intervention, General HPV Multimedia Psychoeducational Control Group
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- University of Texas, El Paso
Knowledge, Attitudes, Practice
The Decision To Enroll In Therapeutic Clinical Trials In A Pediatric Cancer Clinical Network
The focus of this study is to learn about the factors that parents consider when making a decision for their child to participate or not in a clinical treatment research study.
- Trial name
- NCT05454618
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- St. Jude Children's Research Hospital
Alzheimer Disease, Early Onset, Parkinsons Disease with Dementia
Neuropsychological Profiles and Musical Engagement in Parkinson's and Alzheimer's Disease
The goal of this Multicenter observational pilot study is to Compare the specifics of musical engagement (behaviors related to music in everyday life) in subjects aged over 60 with Alzheimer s disease, Parkinson s disease and…
- Conditions
- Alzheimer Disease, Early Onset, Parkinsons Disease with Dementia, Non Pharmacological Intervention
- Trial name
- MUSENGAGE (NCT06688968)
- Testing
- neuropsychologist interview, questionnaire
- Where
- 3 sites in France
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Distress
Treatments for Improving Mood in Women Survivors of Interpersonal Violence: A Community-Engaged Study-1.2
Phase 1.2: Open Trial N=15 women survivors of interpersonal violence will be enrolled into a single-arm pilot trial to test the adapted integrative hatha yoga and mindful self-compassion program.
- Trial name
- I-YMSC (NCT06657950)
- Testing
- Integrative hatha yoga and mindful self-compassion
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Butler Hospital
Anxiety, Carpal Tunnel Syndrome
Effect of High-quality Pre-operative Videos on Patient Anxiety Levels Prior to Ambulatory Hand Surgery
Previous research has shown that YouTube is a poor source of high-quality medical information. This is likely because there is no regulation of the content on YouTube and relatively little of the content is posted by qualified…
- Conditions
- Anxiety, Carpal Tunnel Syndrome, Trigger Finger, Engagement, Patient
- Trial name
- NCT04424810
- Testing
- High-quality, physician created video, Standard of care
- Where
- United States
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Bulimia Nervosa, Binge Eating Disorder
Engaging Latino Families in Eating Disorders Treatment
Promoviendo Alimentacion Saludable (PAS)"Promoting Healthy Eating" is a research project funded by the National Institute of Mental Health.
- Conditions
- Bulimia Nervosa, Binge Eating Disorder, Eating Disorder Not Otherwise Specified
- Trial name
- PAS (NCT01470508)
- Testing
- Cognitive Behavioral Therapy, Cognitive Behavioral Therapy with Family Enhancement
- Where
- 2 sites in United States
- Volunteers
- 25 people
- Sponsor
- Mae Lynn Reyes-Rodriguez, PhD
Hypertension, Pregnancy Induced, Hypertension Complicating Pregnancy
Optimizing Cardiovascular Preventive Care for Women Following Hypertensive Disorders of Pregnancy
Cardiovascular disease is the leading cause of death among women in the United States, and women with hypertensive disorders of pregnancy have a 2-fold higher risk for cardiovascular disease later in life compared to women with…
- Conditions
- Hypertension, Pregnancy Induced, Hypertension Complicating Pregnancy, Preeclampsia, Cardiovascular Diseases
- Trial name
- NCT05826925
- Testing
- Decision aid
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Utah
Depression, Anxiety, Engagement, Patient
Mobile Apps to Reduce Distress in Breast Cancer Survivors Using an Adaptive Design
The overarching goals of this project are to provide the first rigorous test of a scalable and publicly accessible mobile health intervention (IntelliCare) to address emotional distress in women with breast cancer, and to test…
- Trial name
- NCT04583891
- Testing
- IntelliCare, Psychoeducation, Coaching
- Where
- United States
- Volunteers
- 313 people
- Sponsor
- University of Virginia