Clinical trials: Therapeutic Engagement
Patient Engagement, Patient Empowerment
Partnership in Resilience for Medication Safety (PROMIS)
The trial is to assess the impact of two patient partnership tools: (1) a one-page 'visit prep guide' given to relevant patients by clinic staff before seeing the provider, with the intention to improve communication and shared…
- Conditions
- Patient Engagement, Patient Empowerment, Patient Activation
- Trial name
- PROMIS (NCT05880368)
- Testing
- Patient partnership tools
- Where
- 2 sites in United States
- Volunteers
- 405 people
- Sponsor
- The University of Texas at Arlington
Mild Cognitive Impairment (MCI), Alzheimer Disease
Innovative Cognitive Impairment Case Finding and Engagement for Diverse Participation in Alzheimer's Disease Care, Treatment, And Research
Recent studies have highlighted the potential use of electronic health record (EHR) data for scalable and less biased identification of people who may have or be at risk of developing MCI or ADRD at the population level.8,9 Using…
- Conditions
- Mild Cognitive Impairment (MCI), Alzheimer Disease, Alzheimer's Disease (Incl Subtypes), Dementia
- Trial name
- INCLUDE (NCT07016178)
- Testing
- Acceptability and Feasibility of Twistle messaging for PDM+ patients
- Where
- United States
- Volunteers
- 3,454 people
- Sponsor
- Indiana University
Death, Communication, Multidisciplinary
Preserving Compassionate End of Life Care in the Pandemic
Compassionate and humanistic care for patients dying in the hospital has been especially challenging during the pandemic. Family presence is restricted, maximal barrier precautions are advised, and personal protective equipment…
- Conditions
- Death, Communication, Multidisciplinary, Empathy, Compassion
- Trial name
- NCT04602520
- Testing
- 3 Wishes Project
- Where
- Canada
- Volunteers
- 118 people
- Sponsor
- McMaster University
Parkinson Disease
Zesty Exercise System for Therapeutic Engagement
This study will evaluate exercise delivered through the Zesty Exercise System for Therapeutic Engagement (ZEST-E) for people with Parkinson's disease when sessions are monitored either in person or remotely.
- Trial name
- ZEST-E (NCT07382674)
- Testing
- ZEST-E Robot-Assisted Exercise Program
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Emory University
Health Behavior, Colorectal Cancer
Building Engagement Using Financial Incentives Trial - Colorectal Cancer Screening
The goal of this pilot clinical trial is to determine feasibility and explore whether financial incentives paid to primary care patients for completing colorectal cancer screening increase completion of colorectal cancer…
- Conditions
- Health Behavior, Colorectal Cancer, Influenza, COVID-19
- Trial name
- BENEFIT-C (NCT06124131)
- Testing
- Financial incentive for colorectal cancer screening, Financial incentive for flu shot, Financial incentive for COVID-19 shot
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Tulane University
Metabolic Syndrome (MetS)
Use of a Mobile Application for Tracking Physical Activity in the Management of Metabolic Syndrome in Primary Care
This study will explore whether integrating a mobile app to track physical activity-recommended by family doctors during routine primary care visits-can help individuals with metabolic syndrome become more active.
- Trial name
- IMAFIL (NCT07236450)
- Testing
- Mobile Application and Wearable Device for Physical Activity Monitoring
- Where
- Portugal
- Volunteers
- 100 people
- Sponsor
- Andreia Lobo
Specific Phobia
Values Interventions for Increasing Engagement With What is Feared in Individuals With Specific Phobias
Exposure is considered the therapy of choice for specific phobias (SPs). Nevertheless, therapy engagement is extremely limited. SPs are maintained through avoidance of feared stimuli and as such willingness to approach what is…
- Trial name
- NCT05300061
- Testing
- Personal Values Intervention, Prosocial Values Intervention
- Where
- Cyprus
- Volunteers
- 90 people
- Sponsor
- University of Cyprus
Patient Engagement
Developing and Testing a Method for Engagement in Research Using WhatsApp
African immigrants are underrepresented in health research in the United States. Barriers to research participation may include limited access to culturally and linguistically appropriate information, concerns about privacy…
- Trial name
- WI-CARE (NCT07826962)
- Testing
- WI-CARE Protocol
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Pain
Mind Engagement With Music for Nondrug Pain Relief
The purpose of this study is to determine whether engaging in music listening tasks can reduce the perception of pain and provide nondrug pain relief.
- Trial name
- NCT00103870
- Testing
- Electrodermal stimulation, Music listening task
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Utah
Depression, Anxiety, Engagement, Patient
Mobile Apps to Reduce Distress in Breast Cancer Survivors Using an Adaptive Design
The overarching goals of this project are to provide the first rigorous test of a scalable and publicly accessible mobile health intervention (IntelliCare) to address emotional distress in women with breast cancer, and to test…
- Trial name
- NCT04583891
- Testing
- IntelliCare, Psychoeducation, Coaching
- Where
- United States
- Volunteers
- 313 people
- Sponsor
- University of Virginia
Hepatitis C, Substance Use Disorders
Hepatitis C Treatment in PWIDs: MAT or Syringe Exchange Assisted-therapy vs Standard of Care
hepatitis C virus (HCV) has traditionally been treated in subspecialty health centers given the complexity of older pegylated interferon containing regimens, formerly the standard of care.
- Conditions
- Hepatitis C, Substance Use Disorders, Substance Abuse, Intravenous
- Trial name
- NCT03093415
- Testing
- elbasvir-grazoprevir (50 mg/100 mg)
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Oregon Health and Science University
COVID-19 Testing Behaviors
COVID-19 Rapid Test-to-Treat With African American Churches (Faithful Response II)
This 2-arm clustered, randomized community trial will test a multilevel, religiously-tailored COVID-19 rapid, self-testing and treatment intervention against a nontailored, education condition on uptake of COVID-19 rapid testing…
- Trial name
- FRII (NCT07450209)
- Testing
- COVID-19 rapid test-to-treat, Standard COVID19 education control arm
- Where
- United States
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- University of Missouri, Kansas City
Engagement, Patient, Mood
SimpleC Wellness Platform With Social Robot Interaction
This implementation study will be conducted to test a Socially-Assistive Robot (SAR) system for residents in an Assisted Living environment. The goal of the SAR system is to enhance social engagement and connectedness.
- Conditions
- Engagement, Patient, Mood, Quality of Life, Aging
- Trial name
- NCT05296239
- Testing
- SimpleC Wellness Platform with Social Robot Interaction
- Where
- 2 sites in United States
- Volunteers
- 26 people
- Sponsor
- SimpleC, LLC
HIV Treatment
Building Rapid Inpatient Delivery of ART to Generate Engagement in HIV Care
The study team will pilot rapid antiretroviral therapy (ART) initiation as part of routine inpatient care at the University of Chicago Medicine (UCM), comparing outcomes over a 12-month implementation period.
- Trial name
- BRIDGE (NCT07847567)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Chicago
Autism Spectrum Disorder
Characterizing Occupational Therapy Intervention for Children With Autism Spectrum Disorders
This pilot study aims to identify behavioral and neural measures of sensory processing and attention associated with routine occupational therapy intervention for children with autism spectrum disorders.
- Trial name
- NCT05480605
- Testing
- Occupational Therapy
- Where
- 2 sites in United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Ohio State University
HIV, Depression
Enhanced Problem-solving Therapy and HIV Engagement Support to Improve Perinatal Mental Health & HIV Outcomes in Malawi
The main objective of the proposed study is to evaluate the effectiveness of the Enhanced Friendship Bench intervention to improve perinatal depression, HIV care engagement, and infant health outcomes among pregnant women with…
- Conditions
- HIV, Depression, Depression, Postpartum
- Trial name
- NCT06702722
- Testing
- Enhanced Friendship Bench, Enhanced usual care
- Where
- 5 sites in Malawi
- Volunteers
- 400 people
- Sponsor
- University of North Carolina, Chapel Hill
Cataract, Refractive Errors
Strengthening Community- to- Hospital Eye Care Pathways From Boko Eye Care Center in Rural Assam
This operational research project aims to strengthen continuity of eye care delivery between community screening and hospital-based treatment in rural Assam by redesigning referral pathways from the Boko Eye Care Center (ECC) to…
- Trial name
- NCT07333248
- Testing
- Experimental: Integrated Referral and Engagement Model
- Where
- India
- Volunteers
- 2,000 people
- Sponsor
- Seva Canada Society
HIV/AIDS
Duo Partnership Adherence Commitment Therapy
This is a randomized controlled trial of a new behavioral intervention designed to improve engagement in HIV care for couples. Investigators will compare the HIV viral load outcomes of couples randomized to a couples-based…
- Trial name
- DuoPACT (NCT02925949)
- Testing
- DuoPACT, LifeSteps
- Where
- United States
- Volunteers
- 288 people
- Sponsor
- University of California, San Francisco
Schizophrenia
Study of Efficacy of PEAR-004 in Schizophrenia
The purpose of the study was to determine in patients currently being administered antipsychotic pharmacotherapy whether PEAR-004 could further reduce symptoms of schizophrenia as measured by the Positive and Negative Syndrome…
- Trial name
- NCT03751280
- Testing
- PEAR-004
- Where
- 6 sites in United States
- Volunteers
- 112 people
- Sponsor
- Novartis Pharmaceuticals
Pancreas Cancer, Hepatobiliary Cancer
NCI SBIR Contract for Patient Navigation Tool Prototype Development
GMG ArcData will create a mobile-based application to improve communications and data exchange among patients and navigators involved in new pancreas surgery oncology episodes of care.
- Conditions
- Pancreas Cancer, Hepatobiliary Cancer, Patient Engagement
- Trial name
- NCT04892927
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- GMG Arcdata LLC