Clinical trials: Therapeutic Engagement
CHF - Congestive Heart Failure
Digital Outreach for Heart Failure Adherence
The goal of the ADHERE-HF study is to evaluate whether care-embedded, operationally delivered digital outreach improves medication refill, adherence, and clinical outcomes among adults with heart failure who are overdue for a…
- Trial name
- ADHERE-HF (NCT07831538)
- Testing
- Digital Outreach
- Where
- United States
- Volunteers
- 13,714 people
- Sponsor
- Kaiser Permanente
Congestive Heart Failure
Engaging Patients in Heart Failure Management
An interventional study to empower congestive heart failure patients who have a cardiac resynchronization therapy-cardiac implantable electronic device (CRT-CIED) by using a personal health record (PHR) to directly message them…
- Trial name
- NCT02682251
- Testing
- PHR Messaging
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Parkview Health
Breast Cancer
Neoadjuvant Chemo-endocrine Therapy and Immunotherapy for Pre-menopausal Luminal B Breast Cancer Patients
Multicentric, phase II neoadjuvant trial in hormone-positive, HER-negative, luminal B, premenopausal breast cancer patients stage II-IIIA.
- Trial name
- GIADA (NCT04659551)
- Testing
- Epirubicin, Cyclophosphamide, Triptorelin
- Where
- 5 sites in Italy
- Volunteers
- 43 people
- Sponsor
- Istituto Oncologico Veneto IRCCS
Psychiatric Diagnosis
Impact of Telehealth on Engagement in Psychotherapy and/or Medication Treatment
In the present study, investigators aim to (1) adapt the Making Connections Intervention (MCI) as an intervention to address telehealth engagement and examine whether this targeted intervention can improve youth engagement in…
- Trial name
- NCT04931927
- Testing
- Making Connections Intervention-Telehealth (MCI-T), Treatment as usual (TAU)
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- New York State Psychiatric Institute
Cancer, Breast, Cancer Colorectal
Impact of a Patient Decision Aid Intervention
Studies evaluating decisions aids have used a wide range of outcome measures as well as formats and settings. Most studies have focused on patient decision aids used either within the consultation or delivered pre-consultation…
- Trial name
- IMPACTT (NCT05573022)
- Testing
- Pre-consultation electronic patient decision aid, In-consultation paper-based patient decision aid
- Where
- Denmark
- Volunteers
- 274 people
- Sponsor
- Vejle Hospital
Obstructive Sleep Apnea (OSA)
CPAP Population Management
The investigators propose a study to formally compare two Continuous Positive Airway Pressure (CPAP) follow-up pathways: 1) Usual care - follow-up visits reflect standard care practice and we rely on patients to reach out to us…
- Trial name
- NCT04559737
- Testing
- Case Management
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Traumatic Brain Injuries
Therapeutic Benefits of Pareidolia in Acute Traumatic Brain Injury Patients
This study will investigate whether viewing and identifying meaningful shapes or images hidden within nature pictures (pareidolia) can improve motivation and engagement in rehabilitation therapy for adults with mild to moderate…
- Trial name
- NCT07867119
- Testing
- Therapeutic Benefits of Pareidolia, Active Comparator #1
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Shirley Ryan AbilityLab
Autism Spectrum Disorder
Cognoa Autism Spectrum Disorder (ASD) Digital Therapeutic Engagement and Usability Study
Cognoa will measure usability, engagement with the device, and changes in parent-reported socialization during a 4-week period of intervention at home with the Cognoa ASD therapeutic device.
- Trial name
- NCT04326231
- Testing
- Usability assessment of Cognoa ASD Therapeutic Device
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Cognoa, Inc.
Suicide, Health Care Seeking Behavior
Program to Promote Engagement in Care for the Prevention of Recidivism
In France, the number of emergency visits for suicide attempts is estimated at 220,000 per year. Suicide management aims to reduce suicide risk factors in order to improve the mental health of patients and prevent recurrences.
- Conditions
- Suicide, Health Care Seeking Behavior, Case Management
- Trial name
- PEPS (NCT04366466)
- Testing
- suicide attempt patient using PEPS Program
- Volunteers
- 138 people
- Sponsor
- Januel
Autism Spectrum Disorder
Measuring Brain Inflammation in Autism
Autism spectrum disorders (ASD) are highly disabling, persistent neurodevelopmental disorders. There are no available treatments for core symptoms of ASD or biologically-based clinical biomarkers.
- Trial name
- NCT03117530
- Testing
- Minocycline
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Alcoholism, Substance-related Disorders
Treatment Engagement With Technology-assisted Treatment
This research is being done to study whether using an Internet-based program, called the Therapeutic Education System (TES), would be helpful for the treatment of substance use and other psychiatric problems.
- Conditions
- Alcoholism, Substance-related Disorders, Mentally Ill Chemical Abuse, Educational Technology
- Trial name
- TETAT (NCT02674477)
- Testing
- Therapeutic Education System (TES), Treatment as Usual (TAU)
- Volunteers
- 95 people
- Sponsor
- Johns Hopkins University
Patient Satisfaction, Patient Compliance
The Subjective Pre-, Intra-, and Postoperatively Experiences of Patients Undergoing Cataract Surgery.
Assessment of types and intensity of unpleasant experiences pre-, intra-, and postoperatively in the patients undergoing cataract surgery, using especially designed questionnaire.
- Conditions
- Patient Satisfaction, Patient Compliance, Patient Engagement
- Trial name
- NCT04327856
- Testing
- Cataract Surgery
- Where
- 2 sites in Poland
- Volunteers
- 200 people
- Sponsor
- Medical University of Bialystok
Depression
Latina Adolescent Depression Treatment Study
Despite experiencing higher rates of depressive symptoms and similar rates of Major Depressive Disorder (MDD), Latina (female) adolescents in the U.S.
- Trial name
- NCT04164537
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Duke University
Opioid-use Disorder, HIV-1-infection
Anti-retroviral Therapy, Medications for Opioid Use Disorder, Opioids and HIV Infection - Study 1
HIV infection, as well as exposure to opioids (including heroin), are associated with systemic immune activation including increased microbial translocation from the gut.
- Conditions
- Opioid-use Disorder, HIV-1-infection, Immune Activation, Inflammation
- Trial name
- AMOHI-1 (NCT04480554)
- Testing
- Methadone, Buprenorphine/naloxone, XR-Naltrexone
- Where
- 2 sites in United States, Vietnam
- Volunteers
- 78 people
- Sponsor
- University of Pennsylvania
GBAT+Individual, GBAT+Engagement Booster
Transdiagnostic Group Therapy (GBAT) for Autistic Adults With Personalized Therapeutics
The purpose of this study is to build upon an earlier study that evaluated the use of a 10-week transdiagnostic Group Behavioral Activation Therapy (GBAT), a telehealth delivered intervention, as a cost effective and accessible…
- Conditions
- GBAT+Individual, GBAT+Engagement Booster, GBAT+Both
- Trial name
- (GBAT+) (NCT05512221)
- Testing
- GBAT+I, GBAT+E - Phase I, Watchful Waiting and Groups - Phase 2, GBAT+IE
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Rutgers, The State University of New Jersey
Intervention Engagement and Retention
Improving Attendance in Community Wise
Rates of alcohol and substance misuse (ASM) in low-income, predominantly African American communities are similar to the general population.
- Trial name
- NCT05934591
- Testing
- Community Wise
- Where
- United States
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Cataract, Refractive Errors
Strengthening Community- to- Hospital Eye Care Pathways From Boko Eye Care Center in Rural Assam
This operational research project aims to strengthen continuity of eye care delivery between community screening and hospital-based treatment in rural Assam by redesigning referral pathways from the Boko Eye Care Center (ECC) to…
- Trial name
- NCT07333248
- Testing
- Experimental: Integrated Referral and Engagement Model
- Where
- India
- Volunteers
- 2,000 people
- Sponsor
- Seva Canada Society
HIV Infection
Use of Incentives to Engage Drug Users in HIV Therapy
Highly active antiretroviral therapy (HAART), the current standard of care for treatment of HIV infection, is highly effective when taken appropriately.
- Trial name
- Incentives-1 (NCT01526421)
- Testing
- monetary reinforcer
- Where
- Canada
- Volunteers
- 301 people
- Sponsor
- University of British Columbia
Suicide, Attempted
Ketamine Treatment of Youth Suicide Attempters
Ketamine, an NMDA antagonist, has been shown to have rapid anti- suicidal effects. However, its safety and efficacy and special populations has not been investigated and documented.
- Trial name
- NCT04763343
- Testing
- Ketamine Hydrochloride, Saline, CAMS Therapy
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Tatiana Falcone, MD
Metastatic Cancer, Locally Advanced Cancer
An Intervention to Help Patients and Caregivers Manage Stress and Improve Communication Skills When Talking About Cancer
This study will test an intervention to improve patients' and their caregivers' ability to manage difficult emotions and communicate about the patient's illness.
- Conditions
- Metastatic Cancer, Locally Advanced Cancer, Thoracic Cancer, Gynecologic Cancer
- Trial name
- NCT03794635
- Testing
- Weekly 45 minute Sessions
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center