Clinical trials: Therapeutic Engagement
Mild Cognitive Impairment
LifeBio Memory: Development of a Reminiscence Therapy Online Platform With Machine Learning to Increase Engagement
LifeBioMEMORY (LBM) is a reminiscence therapy (RT) mobile application that captures older adults' life stories in their own voices to promote social engagement and psychosocial well-being.
- Trial name
- LifeBio Memory (NCT07685067)
- Testing
- LifeBio Memory (LBM) digital reminiscence intervention
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- George Mason University
Insomnia, PTSD
Treatments in Women Veterans With Insomnia and PTSD
This pilot trial will compare trauma-informed Cognitive Behavioral Therapy for Insomnia (CBT-I) to a psychoeducational intervention in women Veterans with comorbid insomnia and posttraumatic stress disorder (PTSD).
- Conditions
- Insomnia, PTSD, Women Veterans
- Trial name
- NCT05683132
- Testing
- Trauma-Informed CBT-I, PTSD Psychoeducation
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- VA Office of Research and Development
Tobacco Dependence Caused by Cigarettes
Feasibility and Acceptability of Switching to E-cigarettes Among Cigarette Smokers Engaged in SUD Treatment
The purpose of the proposed study is to examine the feasibility of integrating a smoking harm reduction program featuring provision of e-cigarettes and tailored instructions to switch into an existing substance use disorder…
- Trial name
- NCT05918887
- Testing
- NJOY ACE commercial e-cigarette
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of Nevada, Reno
Smoking, Smoking Cessation
Precision Prevention Strategy to Increase Uptake and Engagement in Lung Cancer Screening and Smoking Cessation Treatment
This trial tests the effects of two versions of RiskProfile, a clinically-informed and a genetically-informed version of a patient-specific risk feedback tool, in comparison to usual care, on lung cancer screening and tobacco…
- Conditions
- Smoking, Smoking Cessation, Tobacco Use Cessation
- Trial name
- PRECISE (NCT05627674)
- Testing
- Usual Care, RiskProfile-Clin, RiskProfile-Gen
- Where
- United States
- Volunteers
- 915 people
- Sponsor
- Washington University School of Medicine
Chronic Pain, Chronic Pain Syndrome
Deep Brain Therapy With Low-intensity Ultrasound for Generalized Chronic Pain
This study will evaluate a new form of non-invasive deep brain therapy for individuals with generalized chronic pain. Low-intensity transcranial focused ultrasound stimulation will first be delivered using a range of stimulation…
- Conditions
- Chronic Pain, Chronic Pain Syndrome, Widespread Chronic Pain
- Trial name
- DBT (NCT05674903)
- Testing
- Verum stimulation with Diadem prototype
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- University of Utah
Pathological Gambling
Community Reinforcement Approach and Family Training (CRAFT) for Problem Gambling
Nova Scotia is experiencing a proliferation of gambling opportunities and their related gambling problems. The 2003 Nova Scotia Prevalence Study (2004) found that approximately 50,000 adult Nova Scotians are at some risk for…
- Trial name
- NCT01340274
- Testing
- CRAFT treatment, Treatment as Usual
- Where
- 3 sites in Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- Colchester East Hants Health Authority
Major Depressive Disorder
Brexpiprazole as Adjunctive Therapy in Adults With Major Depressive Disorder
The clinical trial will investigate the effect of brexpiprazole on the concept of life engagement in participants with Major Depressive Disorder (MDD) with a current depressive episode.
- Trial name
- NCT04830215
- Testing
- Brexpiprazole
- Where
- Canada
- Volunteers
- 122 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Hepatitis C, Substance Use Disorders
Hepatitis C Treatment in PWIDs: MAT or Syringe Exchange Assisted-therapy vs Standard of Care
hepatitis C virus (HCV) has traditionally been treated in subspecialty health centers given the complexity of older pegylated interferon containing regimens, formerly the standard of care.
- Conditions
- Hepatitis C, Substance Use Disorders, Substance Abuse, Intravenous
- Trial name
- NCT03093415
- Testing
- elbasvir-grazoprevir (50 mg/100 mg)
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Oregon Health and Science University
Gastro Intestinal Bleeding, Patient Engagement
Patient Important Gastrointestinal Bleeding in the ICU
This study will engage patients and families to create a definition of what matters most to them about upper gastrointestinal (GI) bleeding.
- Conditions
- Gastro Intestinal Bleeding, Patient Engagement, Family Members
- Trial name
- PIB (NCT05506150)
- Testing
- Interviews
- Where
- Canada
- Volunteers
- 51 people
- Sponsor
- McMaster University
Breast Cancer, Prostate Cancer
TIPOPS (Telemedicine vs In Person Oncology Patient Surveillance)
This research study is comparing telemedicine and face-to-face visits to understand patients' experiences with telemedicine versus face to face visits and to understand when it is and is not appropriate to conduct visits remotely
- Conditions
- Breast Cancer, Prostate Cancer, Patient Engagement, Patient Preference
- Trial name
- NCT04936243
- Testing
- FOLLOW UP VISIT-TELEMEDICINE, FOLLOW UP VISIT-FACE TO FACE
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Dana-Farber Cancer Institute
Opioid-use Disorder
Medication Maintenance Therapy in Community Pharmacy Settings
The goal of this study is to compare pharmacy-based medication assisted treatment (MAT) with usual care MAT for people with opioid use disorder.
- Trial name
- MATPharm (NCT04139213)
- Testing
- buprenorphine/naloxone oral product, injectable naltrexone, Pharmacy maintenance addiction care
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Lifespan
Substance Use Disorders
Assertive Community Treatment for Patients Suffering From Substance Use Disorders
According to the World Health Organization the population suffering from addiction problems is increasing. This population is characterized by multiple needs at the medico-psychosocial level.
- Trial name
- NCT03623178
- Testing
- Assertive Community Treatment
- Where
- Switzerland
- Volunteers
- 29 people
- Sponsor
- University Hospital, Geneva
Diabetes
Caring Others Increasing EngageMent in PACT
This trial will compare two methods of increasing engagement in care and success in diabetes management, among patients with diabetes with high-risk features, who also have family members involved in their care.
- Trial name
- CO-IMPACT (NCT02328326)
- Testing
- CO-IMPACT, PACT
- Where
- 2 sites in United States
- Volunteers
- 478 people
- Sponsor
- VA Office of Research and Development
Covid19
SCALE-UP Utah: Community-Academic Partnership to Address COVID-19 Vaccination Rates Among Utah Community Health Centers
SCALE-UP Utah is a community-academic partnership to address COVID-19 among Utah community health centers. The long-term objective of the project is to increase the reach, acceptance, and uptake of COVID-19 vaccines among Utah's…
- Trial name
- NCT04939519
- Testing
- Text-Messaging (TM), Patient Navigation (PN)
- Where
- United States
- Volunteers
- 65,300 people, healthy volunteers welcome
- Sponsor
- University of Utah
Eating Disorder
Target Engagement of a Novel Dissonance-Based Treatment for DSM-5 Eating Disorders
Most people with an eating disorder (ED) do not receive good treatment. The investigators have developed a new brief group treatment that is supposed to work by reducing how much women with an ED value the impossible thinness…
- Trial name
- NCT03261050
- Testing
- Counter Attitudinal Therapy, Interpersonal Therapy
- Where
- 2 sites in United States
- Volunteers
- 83 people
- Sponsor
- Stanford University
Lateral Epicondylitis, Patient Engagement
Comparison of PELOID Therapy and Kinesio Tape Effectiveness in Patients With Lateral Epicondylitis
In this study, the difference in effectiveness between PELOID therapy and kinesio tape in the treatment of lateral epicondylitis; It was planned to evaluate the effects of these treatments on pain, functionality, activities of…
- Trial name
- NCT04687943
- Testing
- PELOID therapy, kinesio tape, exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 3 people
- Sponsor
- Konya Meram State Hospital
Suicide Prevention, Suicide Safety Planning
Suicide Safety Planning
The goal of this clinical trial is to learn the best way to provide suicide prevention care to adults receiving outpatient mental health care.
- Conditions
- Suicide Prevention, Suicide Safety Planning, Suicidal Ideation, Suicide Attempt
- Trial name
- STAY (NCT07783490)
- Testing
- Local Care Continuity, Centralized Care Navigation
- Where
- United States
- Volunteers
- 176,000 people
- Sponsor
- Kaiser Permanente