Clinical trials: Therapy Effect
Mild Cognitive Impairment, Insulin Resistance
Effect of a Modified Ketogenic-Mediterranean Diet on Alzheimer's Disease
The purpose of the BEAM study is to compare the effects of a low-carbohydrate diet and a lowfat diet for adults with mild memory loss and adults with pre-diabetes.
- Trial name
- BEAM (NCT02984540)
- Testing
- Low-Carbohydrate Diet, Low-Fat Diet
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Endoscopy
Effect of the Antihistamine Injection to Prevent Paradoxical Reaction During Sedative Endoscopy
This single-blind prospective study is aimed to investigate the effect of antihistamine as an adjunctive sedative for the patients with histories of severe paradoxical reaction to midazolam during sedative endoscopy.
- Trial name
- NCT03940391
- Testing
- Chlorpheniramine and midazolam, Midazolam
- Where
- South Korea
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Healthy
Biological Response to Meal Ingestion: Gender Differences
Aim: to determine the effect of gender on the sensory and metabolomic responses to a standard probe meal. Participants (12 men and 12 women) will be instructed to eat a standard dinner the day before, to consume a standard…
- Trial name
- NCT03758482
- Testing
- Probe meal
- Where
- Spain
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Epilepsy
Self Acupressure on Fatigue and Sleep Quality in Epilepsy Patients
The aim of this study is to examine the effect of Self-acupressure application on fatigue and sleep quality in epilepsy patients.
- Trial name
- NCT05552924
- Testing
- Self-Acupressure
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Diabetes Mellitus, Acupressure
Effect of Acupressure on Blood Glucose And Anxiety in Elderly With Diabetes
This study aims to evaluate the effects of acupressure on blood glucose levels and anxiety in older adults with diabetes. A three-arm randomized controlled trial will be conducted, comparing acupressure, sham acupressure, and…
- Trial name
- NCT07356024
- Testing
- Acupressure, Routine care
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Trauma Patients
Effect of Severe Trauma on PD1 and Its Legend (PD1/L1) on T Lymphocytes and Correlation With Mortality
Unlike neuro-endocrine response to trauma; posttraumatic immune alterations are not easily carried out at bedside. The majority of trials were conducted in the intensive care usually hours to days post injury.
- Trial name
- NCT04233723
- Testing
- peripheral blood samples
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assiut University
Influence of Mouthpiece Design on Upper Airway Geometry
Evaluation With Scans and Pharyngometry of the Possible Changes in Upper Airway Geometry Induced by Using Different Mouthpieces.
In this study the possible changes in upper airway geometry induced by variations in the characteristics of the mouthpieces of inhalers will be evaluated with functional respiratory imaging (FRI) and Pharyngometry.
- Trial name
- NCT01592929
- Testing
- Magnetic Resonance imaging, Pharyngometry, Computed Tomography scan
- Where
- Belgium
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- FLUIDDA nv
Child Development
Effect of an Innovative BIO Formula Intake on Infant Growth and Tolerance From 0 to 6 Months
From birth to 5 months, milk is the essential and unique food of the newborn. The French National Nutrition Program (PNNS) recommends exclusive breastfeeding "up to 6 months and at least 4 months for a healthy benefit".
- Trial name
- TRUEGREEN (NCT03936257)
- Testing
- Breastfeeding, Conventional BIO Infant formula, TrueGreen BIO infant formula
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Institut Pasteur de Lille
Effect of Low Level Laser Versus Low Intensity Pulsed Ultra Sound on Rate of Different Orthodontic Tooth Movement by Millimeter
Influence of Low-level Laser Therapy Versus Low-intensity Pulsed Ultrasound on Different Orthodontic Tooth Movements
The aim of this prospective clinical project will be to compare the effect of low-level laser therapy versus low intensity pulsed ultrasound on the rate of different orthodontic tooth movements
- Trial name
- NCT06026930
- Testing
- low-level laser therapy
- Where
- Egypt
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Positive Expectations
Positive Expectation Effects on Early Emotional Processing
Insights into the mechanisms of expectation effects in the emotional domain can be invaluable for the development of potential therapeutic interventions for mood disorders.
- Trial name
- NCT07615530
- Testing
- Saline Nasal Spray
- Where
- Germany
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Sarcopenia, Obesity
Citrulline Supplementation Combined With Exercise: Effect on Muscle Function in Elderly People (CITEX Study)
The main objective of this study is to determine if oral supplementation of Citrulline, when combined with HIIT, can produce significant changes in body composition, muscle quality, muscle metabolism and functional capacity in…
- Trial name
- CITEX (NCT02417428)
- Testing
- Citrulline, Exercise, without exercise
- Where
- Canada
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Université du Québec a Montréal
Tobacco Dependence
Predictors of Treatment Outcome for Smokers With and Without Schizophrenia
The primary purpose of this investigation is to determine the predictive value of task persistence as measured by a mirror tracing task.
- Trial name
- NCT00501007
- Where
- United States
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Dietary Intervention
Probiotic, Prebiotic and Synbiotic Effect on Immunity
The aim of the study is to investigate the effect of dietary supplements such as probiotic, prebiotic and synbiotic on the immune response to influenza vaccination and faecal microbiota in adult healthy volunteers.
- Trial name
- NCT01084434
- Testing
- probiotic, prebiotic, Synbiotic
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Reading
Immune System Support
Effect of Probiotic Formula DE111® on Immune System in Preschool Children
Healthy preschool children will be recruited, gastrointestinal infection and respiratory infection symptoms will be followed during the 8-week treatment and 4-week follow-up period, to evaluate the effect of the used probiotic…
- Trial name
- IMMUNOFORM (NCT04077034)
- Testing
- Probiotic Formula Bacillus subtilis DE111®
- Where
- 5 sites in Slovenia
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Deerland Enzymes
Nicotine Withdrawal
Sensorimotor Replacement With Electronic and De-nicotinised Cigarettes
There are currently two sensorimotor replacement products which may be of benefit in smoking cessation: de-nicotinised cigarettes (denics) and electronic cigarettes (ECs), and the purpose of this project is to investigate whether…
- Trial name
- SenRep (NCT01414998)
- Testing
- Stress Ball vs Nicotine-free E-Cigarette, Nicotine-free E-Cigarette vs De-nicotinised Cigarette
- Where
- United Kingdom
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Queen Mary University of London
Pediatric Obesity, Insulin Resistance
Metabolic Effect of Metformin in Obese Insulin Resistant Adolescents With Normal Glucose Tolerance
The primary objective of this randomized, parallel group, double-blind, placebo-controlled study is to determine whether treatment with metformin enhances insulin sensitivity in a group of ethnically diverse obese…
- Conditions
- Pediatric Obesity, Insulin Resistance, Hyperinsulinemia
- Trial name
- NCT00667498
- Testing
- Metformin
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Yale University
Prediabetes, Normoglycemic
Effect of a Collagen Hydrolysate on Postprandial Blood Glucose Profile, Gastric Emptying and GLP-1 Release in Normoglycemic and Prediabetic Subjects
Aim of the study is to investigate the postprandial response on blood glucose, insulin, C-peptide, incretin response and gastric emptying after intake of collagen hydrolysate compared to placebo in normoglycemic and in…
- Trial name
- NCT06789263
- Testing
- Collagen hydrolyzed peptides
- Where
- Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Rousselot BVBA
Non-target Heterologous Effects of Vaccines, Vaccine Interactions
The Interaction Between Measles and DTP Vaccination
The purpose of this study is to investigate for the broad immunological effects of administering measles vaccine (MV) and diphtheria-tetanus-whole cell pertussis vaccine (DTP) to 9 month old Gambian infants, either alone or…
- Trial name
- NCT02710045
- Testing
- Measles Vaccine at 9 months of age, DTP Vaccine at 9 months of age, Measles Vaccine at 18 months of age
- Volunteers
- 302 people, healthy volunteers welcome
- Sponsor
- Medical Research Council Unit, The Gambia
Lumbar Radiculopathy
Effect of High Versus Low-level Laser Therapy in Patients of Lumber Radiculopathy
To Compare the effects of high-level laser therapy (HLLT) and low-level laser therapy (LLLT) on pain in patients with lumbar radiculopathy.
- Trial name
- NCT06240845
- Testing
- High-level laser therapy, Low-level laser therapy
- Where
- 2 sites in Pakistan
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Patient Education, Surgical Fear and Worrying
The Effect of Video-Supported Online Preoperative Education on Fear, Anxiety, Sleep, and Stress
Gallbladder stone disease is among the most common digestive system problems worldwide. The global incidence of gallstones is estimated to be 10-20%. In Europe, this rate is approximately 20%.
- Conditions
- Patient Education, Surgical Fear and Worrying, Surgical Stress Response, Medical-surgical Nursing
- Trial name
- NCT07100275
- Testing
- Patient education, Follow-up via Mobile Health Application
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Bingol University
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