Clinical trials: Therapy Effect
Hyperlipidemias, Xerosis
Combined Effect of Acitretin and Narrow Band Ultraviolet B on Vitiligo Repigmentation
Since abnormal keratinocyte (KC) proliferation and differentiation as well as defective E cadherin expression were reported in vitiligo lesions, the investigators set to study the potential efficacy of combining Retinoids, which…
- Conditions
- Hyperlipidemias, Xerosis, Depression, Liver Diseases
- Trial name
- NCT04245319
- Testing
- Acitretin, Narrow band ultraviolet B
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Healthy
Cold Pressor Test is Used in This Study to Assess the Effect of PF-06305591 on Pain Intensity Evoked by Cold in Healthy Male Subjects
This study will evaluate the pharmacological activity of PF-06305591 in healthy male volunteers by assessing the effects of two dose levels of PF-06305591 on cold pain intensity evoked by keeping non-dominant hand into a water…
- Trial name
- NCT01812265
- Testing
- PF-06305591
- Where
- Belgium
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Pfizer
Dysarthria as Late Effect of Stroke
Efficacy of a Digital Therapeutic for People With Dysarthria After Stroke
This pilot trial will establish the feasibility of a new digitized speech rehabilitation developed for patients with post-stroke dysarthria.
- Trial name
- NCT05146765
- Testing
- Mobile application, Treatment as usual
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Ewha Womans University Seoul Hospital
Neonatal Abstinence Syndrome, Substance Withdrawal, Neonatal
The Effect of Music Therapy on Newborns
The clinical study is evaluating the impact of music therapy on neonates, specifically infants with neonatal opioid withdrawal syndrome (NOWS).
- Trial name
- NCT03987165
- Testing
- Music Therapy
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Tulane University
Quality of Life, Sleep
Effect of Simha Pranayama and Bhramari Pranayama Relaxation Technique on Sleep and Quality of Life
Day end work related mental and muscular tension is quite common among young healthy individuals. This tension dramatically disturb sleeping pattern which also effects QoL.
- Trial name
- NCT07729267
- Testing
- Simha pranayama, Bhramari Pranayama
- Where
- Pakistan
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Mohtishim Ahmed
Nocturia
The Effect of Combined Systematized Behavioural Modification Education Program (SyBeMeP) With DDAVP in Patients With Nocturia
In patients with nocturia, combinational treatment of DDAVP and SyBeMeP might show better outcomes. Systemic video instruction might prove to be beneficial by helping patients have better understanding on treatment and replacing…
- Trial name
- NCT01576900
- Testing
- SyBeMeP (Systemized Behavioural Modification education Program)
- Where
- South Korea
- Volunteers
- 124 people
- Sponsor
- Seoul National University Hospital
Coronary Artery Disease
A Study to Assess the Bioavailability of Different Formulations of AZD5718 and the Food Effect on the Selected Formulation of AZD5718 in Healthy Volunteers
In this study, the relative bioavailability of different formulations of AZD5718 will be determined in order to compare it with the formulation used in a previous Phase 2a study and confirm appropriate drug exposure.
- Trial name
- NCT03420092
- Testing
- Form 1 of AZD5718 tablets, Form 2 of AZD5718 tablets, Form 3 of AZD5718 tablets
- Where
- United Kingdom
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Overweight and Obesity
Evaluation of the Effect of Epitomee Device on Gastric Emptying Rate in Healthy Subjects
Evaluation of the effect of Epitomee Device on Gastric Emptying Rate in healthy subjects
- Trial name
- NCT04485936
- Testing
- Epitomee Device
- Where
- Israel
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Epitomee medical
Infections, Bacterial
Relative Bioavailability Study in Healthy Subjects
Part 1 of this study will assess the relative bioavailability of GSK1322322 administered as one of three investigational tablets compared to powder in a bottle formulation.
- Trial name
- PDF112034 (NCT00924911)
- Testing
- GSK1322322
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
COVID-19
Interferon Beta 1a in Hospitalized COVID-19 Patients
The present study is a randomized, double-blind, placebo-controlled, clinical trial, with the approval of the ethics committee will be conducted on patients who have a positive test confirming COVID-19 in Loghman Hakim Medical…
- Trial name
- IB1aIC (NCT04350671)
- Testing
- Interferon Beta-1A, Lopinavir / Ritonavir, Single Dose of Hydroxychloroquine
- Where
- Iran
- Volunteers
- 40 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
Neck Pain
Effect of Bruegger's Exercise in Chronic Mechanical Neck Pain With Forward Head Posture
The purpose of the study is to investigate the effect of adding Bruegger's exercises on conventional exercise program in treatment of forward head posture.
- Trial name
- NCT07669844
- Testing
- Core stability exercise, Bruegger's training
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Cairo University
Mindfulness, Nurses in COVID-19
Online Mindfulness Therapy for Pandemic Fatigue and Resilience in COVID-19 Nurses
This study evaluates online mindfulness therapy's impact on pandemic fatigue and resilience in COVID-19 quarantine ward nurses. Sixty nurses were divided into experimental and control groups, with the experimental group receiving…
- Conditions
- Mindfulness, Nurses in COVID-19, Pandemic Fatigue, Resilience
- Trial name
- NCT06433544
- Testing
- 6-week online mindfulness course
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Chimei Medical Center
Healthy Volunteers
A Study to Assess the Effects of Epetraborole on the QT Interval in Healthy Adult Subjects
A single-center, 4-way crossover study to evaluate the effect of single therapeutic and supratherapeutic oral doses of epetraborole on the heart rate (HR) corrected QT interval (QTc) by assessing concentration-QT (C-QT)…
- Trial name
- NCT05995444
- Testing
- Epetraborole, Moxifloxacin
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- AN2 Therapeutics, Inc
Oral Bacterial Infection
Evaluation of the Antibacterial Effect of a Toothpaste Containing Zinc Lactate
The aim of this study is to evaluate the antibacterial effect 12 hours after 4-week use of a toothpaste containing amine base, zinc lactate, and fluoride.
- Trial name
- NCT05628571
- Testing
- Zinc toothpaste, Fluoride Toothpaste
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Hospital Israelita Albert Einstein
Depression, Anxiety
The Effect of Mandala Coloring on Depression, Anxiety and Quality of Life of Inpatients in a Psychiatric Clinic
The aim of this study is to examine the effects of mandala coloring activity applied to individuals hospitalized in a psychiatric clinic with a diagnosis of anxiety and depression disorder on quality of life, psychological…
- Trial name
- Mandala (NCT06840171)
- Testing
- Mandala coloring
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- reyhan eskiyurt
Periodontal Diseases
"Effect of CPA/EE Drug on Periodontal Tissue and hsCRP Levels in PCOS Patients With Gingivitis
PCOS is a widely reported condition among young female population and anti-androgen agents are increasingly being used as part of the medical management of such cases.
- Trial name
- NCT05657171
- Testing
- cyproterone Acetate/Ethinyl Estradiol Combination
- Where
- India
- Volunteers
- 47 people
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Life Quality, Hospital Mortality
Effect of Nutritional Support and Early Rehabilitation on Sepsis
Sepsis is a syndrome of life-threatening organ dysfunction caused by a dysregulated host response to infection.Acute catabolic response in critically ill patients struck by sepsis, manifested by massive protein breakdown in a…
- Trial name
- NUSPOTER (NCT05781971)
- Testing
- high protein, rehabilitation, standard protein
- Volunteers
- 1,600 people
- Sponsor
- Jinling Hospital, China
HCC, Racial Disparities
Effect of the HCC Liver-Link Intervention
This study is a pilot, multi-center randomized controlled trial testing the HCC Liver-Link intervention, a culturally tailored, multi-level program designed to reduce racial disparities in hepatocellular carcinoma (HCC) care.
- Trial name
- NCT06728293
- Testing
- Liver Link
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- Indiana University
Diabetic Neuropathies
Effect of Foot Muscle Energy Technique in Patients With Diabetic Neuropathy
Foot muscle energy technique and conventional physical therapy program administered in patients with type 2 Diabetic Neuropathy.
- Trial name
- NCT05790421
- Testing
- Foot Muscle Energy Technique, Conventional Physical Therapy Program
- Where
- Egypt
- Volunteers
- 44 people
- Sponsor
- October 6 University
Infant Pain Management
White Noise and Buzzy for Reducing Pain During Infant Vaccination
This randomized controlled trial aims to evaluate the effectiveness of two non-pharmacological methods-white noise and the Buzzy device-in reducing pain experienced by infants during routine vaccination.
- Trial name
- NCT07286721
- Testing
- Standard Care (in control arm)
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Istanbul Arel University
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