Clinical trials: Therapy Effect
Diabetes Mellitus, Type 2
A Study of the Effect of LY2189265 on Blood Pressure and Heart Rate in Type 2 Diabetes
The purpose of this study is to assess the effects of 2 doses of LY2189265 on blood pressure and heart rate using 24-hour ambulatory blood pressure monitoring (ABPM), in participants with type 2 diabetes mellitus treated with…
- Trial name
- NCT01149421
- Testing
- LY2189265
- Where
- 76 sites in United States, Argentina and 6 more
- Volunteers
- 755 people
- Sponsor
- Eli Lilly and Company
End Stage Renal Disease, Arteriovenous Fistula
Effect of Pre-operative Forearm Exercises on Arterial Venous Fistula Maturation and Blood Flow
This study will investigate the effect of pre-operative exercise on hemodynamics in the fistula artery and vein, Pre and Post Arteriovenous Fistula Formation as well as the suitability of Cannulation of Arteriovenous Fistula at…
- Trial name
- NCT03886116
- Testing
- Exercise
- Where
- Singapore
- Volunteers
- 40 people
- Sponsor
- Singapore General Hospital
Pain, Postoperative, Acute Pain
EFFECT - EFFectiveness of ESPB (Erector Spinae Plane Block) in Laparoscopic Cοlectomies Trial
The aim of the trial is to study the efficacy of continuous bilateral Erector Spinae Plane Block (ESPB) in managing perioperative pain in patients who undergo elective laparoscopic colectomy.
- Conditions
- Pain, Postoperative, Acute Pain, Postoperative Complications, Pain
- Trial name
- EFFECT (NCT04879004)
- Testing
- Ropivacaine injection
- Where
- Greece
- Volunteers
- 40 people
- Sponsor
- Democritus University of Thrace
Cystoid Macular Edema Following Cataract Surgery
PCME Prevention in Patients With NPDR
Pseudophakic cystoid macular edema (PCME), or Irvine-Gass syndrome, is retinal thickening of the macula, which usually develops within 3 months after surgery, with a peak incidence between 4 and 6 weeks.
- Trial name
- NCT04940338
- Testing
- Bromfenac Ophthalmic 0.09% Ophthalmic Solution, Dexamethasone Ophthalmic, Phacoemulsification surgery (PHACO)
- Where
- Croatia
- Volunteers
- 90 people
- Sponsor
- Klinički Bolnički Centar Zagreb
Older People
Multicomponent Training Combined With Multi-professional Intervention Health Status in Hypertensive and Normotensive Older Women
Objective: The objective of this study was to analyze the effects of multicomponent training (MCT) combined with multidisciplinary intervention (nutritional and psychoeducation) on body composition, biochemical markers, and…
- Trial name
- NCT07152158
- Testing
- multicomponent training combined with multi-professional intervention
- Where
- Chile
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Universidad Católica del Maule
Barrett's Esophagus
Effect of Dexlansoprazole 60 mg QD and 60 mg BID on Recurrence of Intestinal Metaplasia in Subjects Who Have Achieved Complete Eradication of Barrett's Esophagus With Radiofrequency Ablation
This study is designed to evaluate the effect of dexlansoprazole once daily (QD) and twice daily (BID) dosing on the recurrence of intestinal metaplasia (IM) in participants who achieved complete eradication of Barrett's…
- Trial name
- NCT02162758
- Testing
- Dexlansoprazole
- Where
- 6 sites in United States
- Volunteers
- 6 people
- Sponsor
- Takeda
No Evidence of Disease
Celecoxib in Preventing the Damaging Effects of Sunburn in Healthy Volunteers
This randomized clinical trial studies if celecoxib will prevent the damaging effects of sunburn in healthy volunteers. Exposure to ultraviolet light can induce erythema, sunburn or skin redness caused by inflammation.
- Trial name
- NCT02099136
- Testing
- UV Light Therapy, Celecoxib, Biopsy
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Leukemia, Acute Lymphoblastic
Effect of Fish Oil on Hyperlipidemia and Toxicities in Children and Young Adults With Acute Lymphoblastic Leukemia
Acute lymphoblastic leukemia (ALL) is the most common malignant disease among children. Treatment results have improved over time due to intensive risk-adapted therapy and the 5-year survival rate is now above 90%.
- Trial name
- NCT04209244
- Testing
- Eskimo-3 Pure Fish Oil, Rapeseed Oil
- Where
- 4 sites in Denmark
- Volunteers
- 100 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Uterus Contractions Pattern
Effect of Dill Seed on Uterus Contractions Pattern
Dill is herbaceous and aromatic herb used in order to convenient and shorter labor in Iran. The objective of this study was to evaluate the effect of Dill seed on uterus contractions in active phase of labor.
- Trial name
- NCT01646164
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Mashhad University of Medical Sciences
Fibromyalgia, Physiotherapy
Effectiveness of the Strain Counterstrain Technique in Women With Fibromyalgia Syndrome
This study evaluates whether strain counterstrain therapy affects pain, fatigue, psychological status, and quality of life in women diagnosed with fibromyalgia.
- Conditions
- Fibromyalgia, Physiotherapy, Pain, Strain Counterstrain Technique
- Trial name
- NCT07421609
- Testing
- Conservative Physiotherapy Program, Strain Counterstrain Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 105 people
- Sponsor
- Hasan Kalyoncu University
Urinary Incontinence
Effect of Glutamine on Urinary Incontinence
The objective of this study is to determine to effect of additional oral glutamine to Kegel exercises on pelvic floor strength and clinical parameters of urinary incontinence in females with either urinary incontinence (stress…
- Trial name
- NCT03265509
- Testing
- glutamine supplementation, fantomalt supplementation
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Istanbul University
Gambling
Gambling and Brief Interventions
This study will compare four different combinations and durations of motivational enhancement therapy, cognitive behavioral therapy, and brief advice treatments for gambling versus a non-intervention condition to determine which…
- Trial name
- NCT00183599
- Testing
- 5 Minutes of Simple Advice, Motivational Enhancement Therapy (MET), Cognitive Behavioral Therapy (CBT)
- Where
- 6 sites in United States
- Volunteers
- 500 people
- Sponsor
- UConn Health
Panic Disorder
Psychoeducation Based on Acceptance and Commitment Therapy
The aim of this study is to manage individual psychoeducation in acceptance and commitment therapy for problems with panic disorder and to evaluate the effect of this program on rumination and self-resilience.
- Trial name
- NCT06704399
- Testing
- Acceptance and Commitment Therapy-Based Psychoeducation, control group
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Muğla Sıtkı Koçman University
Varicose Veins
Effect Of Resistive Exercises Versus Aerobic Exercises On Varicose Veins In Postmenopausal Women
The purpose of this study will be to determine the effect of resistive exercises on varicose veins in postmenopausal women, the effect of aerobic exercise on varicose veins in postmenopausal women and to compare between the…
- Trial name
- NCT06271798
- Testing
- Life style modification advice, Resistive exercise, Aerobic exercises
- Where
- Egypt
- Volunteers
- 44 people
- Sponsor
- Cairo University
Pain
Pilot Study of the Effect of Transcutaneous Stimulation of the Vagus Nerve on Pain Perception and Parameters of the Autonomic Nervous System
The increased incidence of pain syndromes requires the investigation of pathophysiological coherences as well as searching for new therapies.
- Trial name
- NCT01174498
- Testing
- Cerbomed t-VNS® transcutaneous stimulation
- Where
- Germany
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- cerbomed GmbH
Posttraumatic Stress Disorder
Neuroprotective/Neurotrophic Effect of Lexapro® in Patients With Posttraumatic Stress Disorder
The objectives of the current study are 1. to evaluate the efficacy of escitalopram in treatment for post-traumatic stress disorder, 2.
- Trial name
- NCT01008098
- Testing
- escitalopram (lexapro)
- Where
- South Korea
- Volunteers
- 26 people
- Sponsor
- Seoul National University Hospital
Hypertension
Effect Of Nigella Sativa Oil for the Treatment of Hypertension
My research explores the antihypertensive effects of Nigella sativa (black seed) oil in managing high blood pressure. Hypertension is a growing global health concern, often insufficiently controlled by standard medications.
- Trial name
- NCT07055763
- Testing
- Nigella sativa (black seed)
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Superior University
Caregiver, Education
The Psychobiological Effects of Laughter Yoga: An Intervention Study
This study was conducted to determine the effect of Laughter Yoga-Based Mental Health Enhancement Training, applied to mothers of children with special needs, on the burden of care, positive mental health, perceived stress, and…
- Trial name
- NCT07314463
- Testing
- Laughter Yoga-Based Mental Health Strengthening Training
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Pain, Postoperative
Analgesic Effect of Three-point Transversus Abdominis Plane Block Compared With Continuous Epidural Infusion for Post-laparoscopic Nephrectomy
This study aimed to compare the efficacy three-point Transversus Abdominis Plane (TAP) blocks with continuous epidural infusion for alleviating pain post-laparoscopic nephrectomy
- Trial name
- NCT03154463
- Testing
- TAP Blocks, continuous epidural infusion
- Where
- Indonesia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Acute Upper Respiratory Tract Infection
The Multistrain Probiotic OMNi-BiOTiC® Active for Upper Respiratory Tract Infections in Older People
The goal of this randomised controlled trial is to determine the effect of consuming a multistrain probiotic OMNi-BiOTiC® Active to shorten the incidence and duration of acute upper respiratory tract infections (URTIs) in older…
- Trial name
- ProURTI (NCT05879393)
- Testing
- OMNi-BiOTiC® Active
- Where
- Slovenia
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- University Maribor
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