Clinical trials: Therapy Effect
B Acute Lymphoblastic Leukemia, B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1
Studying the Effect of Levocarnitine in Protecting the Liver From Chemotherapy for Leukemia or Lymphoma
This phase III trial compares the effect of adding levocarnitine to standard chemotherapy versus (vs.) standard chemotherapy alone in protecting the liver in patients with leukemia or lymphoma.
- Conditions
- B Acute Lymphoblastic Leukemia, B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1, B Acute Lymphoblastic Leukemia, BCR-ABL1-Like, Lymphoblastic Lymphoma
- Trial name
- NCT05602194
- Testing
- Biospecimen Collection, Calaspargase Pegol, Levocarnitine
- Where
- 228 sites in United States, Canada
- Volunteers
- 440 people
- Sponsor
- Children's Oncology Group
Healthy
Effect of Diets on the Gut Microbiota Composition and Cardiometabolic Wellbeing
The project will characterize human gut microbiome response to two different diets and the possible physiological and biochemical implications of such response on cardiometabolic risk factors.
- Trial name
- NCT03539666
- Testing
- diet
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- South Dakota State University
PEMF Effect
PEMF Stimulation on Physical Exercise in Sedentary People
The pulsed electromagnetic fields (PEMF) are a non-invasive therapy used for clinical treatments. Recent publications in exercise physiology showed that PEMF enhanced the velocity and the quantity of available muscle O2, and the…
- Trial name
- NCT06446466
- Testing
- PEMF ON-OFF, PEMF OFF-ON
- Where
- Italy
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Bologna
Molar Intrusion, Ozonated Olive Oil
Ozonated Olive Oil for Mini-Screw Complications in Molar Intrusion
The goal of this clinical trial was to learn whether ozonated olive oil can reduce complications around orthodontic mini-screws in patients with anterior open bite who receive maxillary molar intrusion as part of fixed…
- Conditions
- Molar Intrusion, Ozonated Olive Oil, Chlorhexidine
- Trial name
- NCT07900022
- Testing
- Ozonated Olive Oil, Chlorhexidine
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Yuzuncu Yil University
Temporomandibular Joint Disorders
Effect of Mask Use on Jaw Functionality
Due to COVID-19 pandemic the use of masks has been made mandatory to prevent contagion. Individuals concluded that the use of masks has a negative effect on temporomandibular joint functions.
- Trial name
- NCT06103851
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Apathy, Parkinson Disease
Effect of Istradefylline Treatment on Behavioral Measures of Apathy in Parkinson's Disease.
Apathy is defined as a lack of feeling, emotion, interest, or concern. Apathy also involves reduction or loss of motivation and goal-directed behavior.
- Trial name
- NCT05182151
- Testing
- Istradefylline 40 mg
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Medical University of South Carolina
Impaired Glucose Tolerance, Diabetes
Effect of Ginseng on Glycemic Control
Ginseng (American ginseng, Asian ginseng, Korean ginseng etc) is expected to show positive hypoglycemic effects, including improvements in glycated blood proteins[HbA1c], fasting glucose, fasting insulin, and the homeostasis…
- Trial name
- NCT01841229
- Where
- Canada
- Volunteers
- 770 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Coronary Artery Disease
Colchicine Protective Effect in Patients Undergoing Percutaneous Coronary Intervention (COLCHICINE-PROTECT)
The goal of this clinical trial is to evaluate the colchicine protective effect in patients undergoing Percutaneous Coronary Intervention (PCI).
- Trial name
- NCT05739929
- Testing
- Colchicine 0.5 MG Oral Tablet
- Where
- Egypt
- Volunteers
- 400 people
- Sponsor
- Helwan University
Peripheral Vestibular Disorder, Benign Paroxysmal Positional Vertigo
Effect of Peripheral Vestibular Disease Location on Outcomes Following Home-based Virtual Reality Vestibular Therapy
This parallel-group randomized controlled trial aims to determine if the location of the lesion(s) in the vestibular system (unilateral versus bilateral, lateral semi-circular canal versus otolith) impacts the effectiveness of…
- Conditions
- Peripheral Vestibular Disorder, Benign Paroxysmal Positional Vertigo, Meniere Disease, Vestibular Neuritis
- Trial name
- VR-PVD-RCT (NCT05424302)
- Testing
- Standard Vestibular Rehabilitation with Adjunct At Home Virtual Reality Vestibular Rehabilitation, Standard Vestibular Rehabilitation with Adjunct Auditory Intervention
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Adenoma Colon
The Effect of Clip-traction on ESD Resection Time.
Patients scheduled for an endoscopic submucosal dissection(ESD) in the colorectum will be randomized to the use of a traction device(consisting of an endoscopic clip with a loop of dental floss secured in the lesion to be…
- Trial name
- NCT04756453
- Testing
- clip-traction
- Where
- Sweden
- Volunteers
- 280 people
- Sponsor
- Karolinska Institutet
Low Back Pain
Dry Needling at the Thoracolumbar Junction on Measures of Sympathetic Outflow and Flexibility
Dry needling (DN) is becoming more frequently performed by physical therapists around the world to treat musculoskeletal pain. Dry needling is a form of trigger point therapy that evolved from using injections of local…
- Trial name
- NCT03630172
- Testing
- Dry needling
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Nova Southeastern University
Stroke, Ambulation Difficulty
Effect of Functional Electric Stimulation for Recovery of Dorsiflexion After Stroke
The purpose of this project is to investigate the effect of functional electrical stimulation (FES) for recovery of dorsiflexion after stroke.
- Conditions
- Stroke, Ambulation Difficulty, Hemiplegia
- Trial name
- NCT04945395
- Testing
- FES and Conventional training, AFO and Conventional training
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- Danderyd Hospital
Breast Cancer, Estrogen Receptor-positive Breast Cancer
Evaluation of Endocrine Therapy Effects of Host Immunity in Early Stage Breast Cancer
The purpose of this research study is to learn about the effects that standard of care endocrine therapies have on the immune system's response to cancer by looking at the number and types of immune cells present and how they…
- Conditions
- Breast Cancer, Estrogen Receptor-positive Breast Cancer, Healthy
- Trial name
- NCT03719495
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Duke University
Testicular Abnominalies
Study to Evaluate the Effect of Zoliflodacin on Testicular Function in Healthy Adult Men
This study is a randomized, double-blind, placebo-controlled clinical trial to evaluate the effect of zoliflodacin on testicular function in healthy adult men.
- Trial name
- NCT07640477
- Testing
- Zoliflodacin
- Where
- 2 sites in Germany, United Kingdom
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Global Antibiotics Research and Development Partnership
Gingival Recession, Localized
Impact of Microneedling on Coverage of RT1 Gingival Recession in Thin Phenotype.
Gingival Recession (GR) is a common finding among adults, regardless of the oral hygiene levels. When it is associated with esthetic impairment, dentin hypersensitivity, root caries, surgical treatment is indicated.
- Trial name
- NCT06432439
- Testing
- microneedling followed by CAF procedures, CAF procedure
- Where
- India
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Knee Osteoarthritis
The Effect of Training With Custom-Made Biomechanical Perturbation Platform on Kinetics, Kinematics and Electromyography in Knee Osteoarthritis Patients
The aim of this study is to evaluate the outcome of specific repetitive biomechanical perturbation training on motor patterns. The first hypothesis of this project is that footwear derived biomechanical challenges will convey…
- Trial name
- NCT00724139
- Testing
- : APOS biomechanical gait system, Apos - Sports and Medical Technologies Ltd. Hertzlia, Israel
- Where
- Israel
- Volunteers
- 15 people
- Sponsor
- HaEmek Medical Center, Israel
Effect of Carriere® Motion™ Appliance on Pharyngeal Airway Dimensions, Effect of Carriere® Motion™ Appliance on Skeletal and Dental Measurements
Effect of Carriere® Motion™ Appliance on Airway Dimensions
Objectives: to evaluate the effect of treatment with Carriere® Motion™ Appliance on pharyngeal airway, skeletal and dental dimensions using lateral cephalometric radiographs and to compare these changes with a control group.
- Trial name
- NCT04900077
- Testing
- Carriere® Motion™ Appliance
- Where
- Saudi Arabia
- Volunteers
- 42 people
- Sponsor
- King Abdulaziz University
Gastric Cancer (GC), Stomach Neoplasms
TEAS Timing for Gastrectomy Recovery (TEAS-TIME Trial)
The goal of this clinical trial is to learn if transcutaneous electrical acupoint stimulation (TEAS) works to help people recover faster after laparoscopic surgery for stomach cancer.
- Trial name
- NCT07714980
- Testing
- Transcutaneous Electrical Acupoint Stimulation
- Where
- 13 sites in China
- Volunteers
- 300 people
- Sponsor
- The Affiliated Hospital of Qingdao University
Basic Life Support, Student Education
The Effect of Video-Assisted and Game-Based Approaches on Basic Life Support Training
Adult Basic Life Support (BLS) is a critical skill in emergency situations. Teaching this skill effectively to students in first aid and emergency aid programs is essential for imparting both theoretical knowledge and practical…
- Conditions
- Basic Life Support, Student Education, Video-Assisted, Interactive Teaching
- Trial name
- NCT06758180
- Testing
- verbal basic life support training, Interactive game intervention, video training
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Abant Izzet Baysal University
Diabetes, Proteinuria
The Effect of Renin Angiotensin System Blockage (RAS) Blockade On PTX3 Levels In Diabetic Patients With Proteinuria
Long pentraxin 3 (PTX3) is a recently discovered multimeric inflammatory mediator structurally linked to CRP and serum amyloid P-component.
- Conditions
- Diabetes, Proteinuria, Renin Angiotensin System
- Trial name
- NCT00674596
- Testing
- ramipril
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Gulhane School of Medicine
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