Clinical trials: Therapy Strategies
Paancreatic Cancer
New Predictive Marker for Pancreatic Cancer Using CA19-9 and Fecal Elastase
Background Carbohydrate antigen 19-9 (CA19-9) is used as a marker to predict recurrence and survival of patients with Pancreatic cancer(PDAC).
- Trial name
- NCT05923567
- Where
- South Korea
- Volunteers
- 150 people
- Sponsor
- Gangnam Severance Hospital
Kidney, Injury
Intensive Insulin Therapy and Acute Kidney Injury. Analysis Using RIFLE Criteria.
The purpose of this study is to determine if intensive insulin therapy really reduces the incidence of acute kidney injury in critically ill patients, using for analysis the RIFLE criteria for definition of AKI.
- Trial name
- NCT00738504
- Where
- Brazil
- Volunteers
- 337 people
- Sponsor
- Hospital Sao Domingos
Opioid Use Disorder (OUD), Chronic Pain
Opioid Adherence and Support Through Innovative Texting Strategies
The goal of this clinical trial is to examine the effects of reminder and mindfulness text messages on medication adherence and managing craving, pain, and withdrawal symptoms in people taking medications for opioid use disorder…
- Trial name
- OASIS (NCT07350148)
- Testing
- Mindfulness text messages
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of New Mexico
Diabetes; Neuropathy, Polyneuropathy (Manifestation)
FOot CAre and Exercises ImplementatioN for People With Diabetes in Primary Care
The main objective of this type 2 hybrid implementation effectiveness trial is to implement a contextually appropriate preventive intervention for 12 weeks face to face group foot and ankle exercises for people with diabetic foot…
- Trial name
- FOCAIN (NCT05639478)
- Testing
- Foot-related exercises
- Where
- Brazil
- Volunteers
- 356 people
- Sponsor
- University of Sao Paulo General Hospital
End Stage Renal Disease on Dialysis
MoVE Trial: Motivational Strategies to Empower African Americans to Improve Dialysis Adherence
MoVE Trial is a randomized clinical trial designed to rigorously test the impact of a behavioral intervention (culturally tailored motivational interviewing - (MOVE)) delivered by trained health coaches, on hemodialysis treatment…
- Trial name
- NCT05735743
- Testing
- Motivational interviewing
- Where
- 6 sites in United States
- Volunteers
- 176 people
- Sponsor
- Vanderbilt University Medical Center
Obesity and Overweight
Smart Nutrition, Healthier Communities
The project investigates the effect of the health app Lifeness as a digital therapeutic (DTx) and follow-up tool in a municipal setting at a regional Healthy Lives Center in central Norway (Frisklivssentralen Værnesregionen)…
- Trial name
- NCT06667843
- Testing
- Lifestyle Management, Intervention, Control
- Where
- 2 sites in Norway
- Volunteers
- 37 people
- Sponsor
- Norwegian University of Science and Technology
Ankle Dorsiflexion
Red Light Therapy: a Potential Strategy to Reduce Sports Injury Risk?
This study investigates whether near-infrared light therapy can acutely improve ankle dorsiflexion mobility and hamstring flexibility, two factors associated with sports injury risk.
- Trial name
- DIAERESIS (NCT07477678)
- Testing
- Near-infrared photobiomodulation, Cycling Warm-up
- Where
- Portugal
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cláudio da Silva Ferreira
Asthma
A Translational Study to Describe Clinical Characteristics, Biomarkers and to Identify Phenotypes and Endotypes Associated With Differential Outcomes in Chinese Population
A Translational Study to Describe Asthma Patient Clinical Characteristics, Treatment Patterns, Biomarkers and to Identify Phenotypes and Endotypes associated with Differential Outcomes that may Support Future Development of…
- Trial name
- NCT06419413
- Where
- 21 sites in China
- Volunteers
- 355 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Rectal Cancer, Rectal Adenocarcinoma
Chemo-radiotherapy as Main Treatment Strategy for Rectal Cancer. Can we Provide a More Precise and Effective Treatment
The purpose of this project is to obtain important information about the tumour and surrounding organs during preoperative chemo-radiotherapy for patients with adenocarcinoma of the rectum.
- Conditions
- Rectal Cancer, Rectal Adenocarcinoma, Locally Advanced Malignant Neoplasm
- Trial name
- AMPERE (NCT03619668)
- Where
- Denmark
- Volunteers
- 16 people
- Sponsor
- Aalborg University Hospital
Asthma
Evaluation of an Asthma Treatment Strategy Based on Exhaled Nitric Oxide Measurements in Adolescents
The purpose of ICAC-01 is to determine whether an asthma treatment strategy that measures exhaled nitric oxide (eNO) to indicate disease progression is more effective in treating asthma symptoms when combined with existing asthma…
- Trial name
- NCT00114413
- Testing
- Inhaled corticosteroids, eNO measurement
- Where
- 12 sites in United States
- Volunteers
- 547 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Cerebral Palsy (CP)
Metacognitive Strategy Training Intervention for Transition-Age Youth With Cerebral Palsy
This exploratory randomized controlled trial will examine the feasibility and preliminary effects of a remote PREP intervention compared to an attention control for transition-age youth with cerebral palsy and their caregivers.
- Trial name
- NCT07424079
- Testing
- Pathways and Resources for Engagement and Participation, Attention Control Condition
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Missouri-Columbia
Refractory Cardiac Arrest
Feasibility Study on a Prehospital Extracorporeal CardioPulmonary Resuscitation in the Pavia's Province.
This is a single Center interventional study, assessing the feasibility of a complex treatment strategy where an in-hospital standard care process is applied in an out-of-hospital cardiac arrest.
- Trial name
- eCPR on Site (NCT07155772)
- Testing
- Extracorporeal CardioPulmonary Resuscitation (eCPR)
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Obesity, Weight Loss
Project Activate: Mindfulness and Acceptance Based Behavioral Treatment for Weight Loss
Mindfulness and Acceptance based Behavioral Therapies (MABTs) are among the most promising behavioral approaches for obesity, with two recent large trials showing that they achieve better initial weight loss and/or better weight…
- Trial name
- Activate (NCT04337619)
- Testing
- Behavioral Treatment, Willingness, Values
- Where
- United States
- Volunteers
- 276 people
- Sponsor
- Drexel University
Ischemic Stroke, Transient Ischemic Attack
Treat Stroke to Target
The aim of this study is the evaluation of two usual care strategies after stroke or TIA : achieved target LDL-C of 100 mg/dL (+/-10 mg/dL) or less than 70 mg/dL.
- Conditions
- Ischemic Stroke, Transient Ischemic Attack, Atherosclerotic Stenosis
- Trial name
- TST (NCT01252875)
- Testing
- Target : 100 mg/dL (+/-10 mg/dL), 70 mg/dL
- Where
- 2 sites in France
- Volunteers
- 2,873 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
HIV, Medication Adherence
Tel-Me-Box: Testing a New, Real-time Strategies for Monitoring HIV Medication Adherence in India
Currently available methods to monitor antiretroviral (ARV) adherence to HIV treatment and prevention, such as self-report, pill counts, medication electronic monitoring system (MEMS), and devices which wirelessly monitor…
- Trial name
- NCT03086655
- Testing
- Tel-me-box with reminder features, Tel-me-box
- Where
- India
- Volunteers
- 131 people
- Sponsor
- University of California, San Francisco
Posttraumatic Stress Disorder, Combat-related
Predictors of Treatment Response to Fluoxetine in PTSD Following a Recent History of War Zone Stress Exposure
Three hundred (300) male or female outpatients, over 18 years of age, will be enrolled in this study to determine whether fluoxetine can be used as a treatment for Posttraumatic Stress Disorder in soldiers recently returning from…
- Trial name
- NCT00633685
- Testing
- Fluoxetine
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- TEMPVA Research Group, Inc.
Sick Sinus Syndrome
Pacing of the Atria in Sick Sinus Syndrome Trial Preventive Strategies for Atrial Fibrillation
The purpose of this study is to determine which of 4 lead positions is most effective for pacemaker patients with Sick Sinus Syndrome in order to avoid development of atrial fibrillation.
- Trial name
- NCT00161538
- Testing
- Pacing leads to be implanted according randomization., Selection 9000 prevent AF an Diagnose AF
- Where
- 12 sites in Germany
- Volunteers
- 456 people
- Sponsor
- Medtronic BRC
Non Small Cell Lung Cancer
Adjuvant Therapy Omission for Resected NSCLC Patients With Longitudinal Undetectable MRD
Molecular residual disease (MRD) has strong relationship with clinical outcome in multiple solid tumors. Here, the investigators try to verify the negative predictive value of undetectable MRD, which is considered as a superior…
- Trial name
- NCT05457049
- Testing
- Molecular residual disease test
- Where
- 5 sites in China
- Volunteers
- 180 people
- Sponsor
- Guangdong Association of Clinical Trials
Antibody-drug Conjugates, HER2-low Breast Cancer
Analysis of Exploring Optimized Sequential Treatment Strategies of Antibody-Drug Conjugates (ADCs) in HER2-Low-Expressing Breast Cancer
This study retrospectively analyzes the clinical data of HER2-low breast cancer (IHC 1+/2+ and FISH-negative) patients treated with sequential antibody-drug conjugates (ADCs).
- Conditions
- Antibody-drug Conjugates, HER2-low Breast Cancer, Breast Neoplasms
- Trial name
- NCT06877416
- Testing
- Non-intervention research
- Where
- China
- Volunteers
- 700 people
- Sponsor
- Sun Yat-sen University
Cerebral Infarction
Observation of the Therapeutic Effect of Fire Needle on Upper Limb Function in Stroke Patients
Objective: To explore the clinical efficacy of different needling strategies with moxibustion needles on upper limb function in post-stroke patients.
- Trial name
- NCT07140406
- Testing
- conventional rehabilitation training, conventional acupuncture, Acupuncture with the milli-needle fire-puncture on flexor muscle groups
- Where
- China
- Volunteers
- 105 people
- Sponsor
- Qilu Hospital of Shandong University
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