Clinical trials: Thermosensing
Healthy
Local Changes of Skin Characteristics After an Application of a Topical Product With a Warming or Cooling Effect
The use of topical over-the-counter (OTC) products with a warming or cooling effect is widespread in the fields of sport, physiotherapy and in private households.
- Trial name
- SRPT (NCT03016221)
- Testing
- Axanova hot gel, Axanova activ gel, Perskindol Dolo Gel
- Where
- Switzerland
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Applied Sciences and Arts of Southern Switzerland
Healthy
Ultrasound Guided Local Anesthetic Block: Thoracolumbar Interfascial Plane
The purpose of the study is to determine the effectiveness of a new approach to numbing (anesthetizing) nerves in the back and to measure how far the area of anesthesia extends on the skin of the back.
- Trial name
- TLIP (NCT02297191)
- Testing
- Thoracolumbar Interfascial Plane Block, Ropivicaine
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Neuropathic Pain
Brain Activation During Thermal Stimulation in Neuropathic Pain
Patients with peripheral neuropathy frequently exhibit treatment-refractory neuropathic pain. Although both peripheral and central determinants are recognized for the pathophysiological basis of neuropathic pain following…
- Trial name
- NCT00525018
- Testing
- contact heat evoked potential stimulator
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Neuropathic Pain
Patterns of Cerebral Activation to Innocuous and Noxious Heat Stimulations in Neuropathic Pain
Patients with neuropathic pain exhibit hyperalgesia and allodynia. Although both peripheral and central determinants are recognized for the pathophysiological basis of neuropathic pain following peripheral injury, the modulating…
- Trial name
- NCT00713024
- Where
- Taiwan
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Pain, Acute
Transauricular Vagal Nerve Stimulation, Pressure Pain and Interoception
Interoception, the ability to perceive, process and respond to signals originating from within the body, is crucial for maintaining healthy physiological ranges.
- Trial name
- NCT06240026
- Testing
- taVNS, Earlobe Stimulation
- Where
- Denmark
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Cold Exposure, Body Temperature Regulation
Hand Cooling With Ice Packs in Healthy Young Men
This randomized, parallel-group study looked at how a standard 15-minute ice pack applied to the back of the hand affects skin temperature and how cold and comfortable the hand feels, compared with a room-temperature water pack.
- Conditions
- Cold Exposure, Body Temperature Regulation, Thermal Comfort Perception
- Trial name
- ICEHAND (NCT07254182)
- Testing
- Ice Pack (Localized Cryotherapy), Thermoneutral Water Pack (Control)
- Where
- Poland
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Pain, Postoperative, Numbness
Lidocaine Versus Bupivacaine in Orthognathic Surgery
In this research study, we want to learn more about the impact of two different local anesthetics (bupivacaine and lidocaine) on patient experience following orthognathic (jaw) surgery.
- Conditions
- Pain, Postoperative, Numbness, Temperature Sensation, Perception of Touch
- Trial name
- NCT06450028
- Testing
- 10 cc of 0.25% bupivacaine hydrochloride with 1:200,000 epinephrine, 6.8 cc of 2% lidocaine hydrochloride with 1:100,000 epinephrine
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Performance Enhancing Product Use, Change, Body Weight
Effects of Acute Glycerol Ingestion on Performance, Metabolic and Biochemical Markers in International Athletes
This clinical study evaluates the acute effect of glycerol ingestion on performance (power output), weight, urine specific gravity, biochemical (antioxidants and lactate) and metabolic (indirect calorimetry) markers in…
- Conditions
- Performance Enhancing Product Use, Change, Body Weight, Change, Body Temperature, Antioxidative Stress
- Trial name
- NCT05295836
- Testing
- GLYCEROL
- Where
- Spain
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Francisco Javier Martínez Noguera
Heat Stress, Athletic Performance
Effectiveness of Topical Menthol as A Cooling Method During Exercise in A Recreational Runner Population
The goal of this clinical trial is to evaluate the effectiveness of topical menthol as a cooling method during exercise in a hot air environment in healthy adult recreational runners aged 18 to 45 years.
- Trial name
- NCT07482046
- Testing
- Light blue gel with the trademark Counterpain COOL® (License Number: POM QD. 111 709 501) containing the active substance Menthol 4%.
- Where
- Indonesia
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Taisho Pharmaceutical Indonesia