Clinical trials: Theta Burst Stimulation
Autism Spectrum Disorder, Theta Burst Stimulation
Explore the Impacts of One Session and Multiple Session Theta Burst Stimulation Over Cerebellum in Adults With Autism Spectrum Disorder
This study aims to establish a personalized theta burst stimulation (TBS, an advanced variant of repetitive transcranial magnetic stimulation, rTMS) protocol considering autistic idiosyncrasy (interindividual variability).
- Trial name
- NCT07114770
- Testing
- Theta Burst Stimulation (TBS, an advanced variant of repetitive transcranial magnetic stimulation)
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Mild Cognitive Impairment
iTBS rTMS in Mild Cognitive Impairment
The purposes of this research are to test whether it is feasible to administer a treatment protocol called intermittent theta burst stimulation (iTBS) repetitive transcranial magnetic stimulation (rTMS) in adults with mild…
- Trial name
- NCT05327257
- Testing
- iTBS rTMS
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Maria I. Lapid, M.D.
Tobacco Use Disorder
Theta-burst Repetitive Transcranial Magnetic Stimulation (TBS) of the Right Inferior Frontal Gyrus for Treatment of Nicotine Dependence
The purpose of this research study is to examine the effects of theta-burst Transcranial Magnetic Stimulation on inhibitory control and smoking among adult cigarette smokers.
- Trial name
- NCT05389670
- Testing
- Continuous Theta-burst stimulation (cTBS)
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Brain Connectivity
Resting State Changes Following Theta Burst Stimulation
Transcranial magnetic stimulation (TMS) is increasingly being applied to effectively treat mental illness, however efforts to quantify the effects of TMS on the network architecture of the brain have largely been limited in scope…
- Trial name
- NCT05322239
- Testing
- Intermittent Theta Burst Stimulation, Continuous Theta Burst Stimulation
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Nicholas Balderston, PhD
Healthy
Prefrontal iTBS on Working Memory
The investigators previous pilot study showed that the brain remained activated after 3 minutes of intermittent theta burst stimulation (iTBS).
- Trial name
- NCT05774223
- Testing
- Transcranial magnetic stimulation (TMS)-active
- Where
- Hong Kong
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Cannabis
Transcranial Magnetic Brain Stimulation to Reduce Cannabis Use in Heavy Cannabis Users
The growing legalization of cannabis across the U.S. is associated with increases in cannabis use, and accordingly, an increase in the number of individuals with cannabis use problems, including cannabis use disorder (CUD).
- Trial name
- iCURE (NCT05401929)
- Testing
- iTBS
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Duke University
Ischemic Stroke,
Intermittent Theta Burst Stimulation After Acute Stroke
This pilot sham-controlled study aims to determine the safety and efficacy of repetitive transcranial magnetic stimulation given as a facilitatory intermittent theta burst stimulation (iTBS1200, 1200 stimuli/session) paradigm to…
- Trial name
- NCT01323881
- Testing
- Intermittent theta burst stimulation
- Where
- Taiwan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Healthy
Exploring the Cortical Hemodynamic Response of Excitatory Brain Stimulation: a Pilot Study
Intermittent theta-burst stimulation (iTBS) is a promising treatment for major depressive disorder. However, fewer than 50% of patients show sufficient response. Therefore, the optimal treatment protocol is worth investigating.
- Trial name
- NCT05427552
- Testing
- Intermittent theta-burst stimulation (iTBS)
- Where
- Hong Kong
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Bipolar Disorder
Effects of Theta Burst Stimulation on the Brain, Behavior, and Clinical Symptoms in Adults With Bipolar Disorder
Bipolar Disorder (BD) is a common and highly debilitating psychiatric disorder, however, the predisposing brain mechanisms are poorly understood.
- Trial name
- NCT04696471
- Testing
- Continuous Theta Burst Stimulation (cTBS)
- Where
- United States
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Mary Phillips, MD MD (Cantab)
Depression
The Effects of ECT and/or iTBS on Olfaction and Cognition in Patients With Depression
The sense of smell and cognition are known to be closely associated with mood and emotional processes. However, despite the clear links between olfaction and cognitive processes with emotional states, research into the role of…
- Trial name
- NCT02804347
- Testing
- Cognitive Function Imaging and Battery, Sniffin Sticks, Cognitive Batteries
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Queen's University
Treatment Resistant Depression (TRD), Transcranial Magnetic Stimulation
Accelerated Transcranial Magnetic Stimulation in Treatment-Resistant Depressed Patients
Depression is the leading cause of disability worldwide and around 800,000 suicides occur each year. According to the World Health Organization, major depressive disorder (MDD) is expected to be the leading cause of the global…
- Conditions
- Treatment Resistant Depression (TRD), Transcranial Magnetic Stimulation, Accelerated Protocol, Sham-controlled
- Trial name
- NCT06783361
- Testing
- Transcranial Magnetic Stimulation with figure-eight coil
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Neuromodulation
Optimization of ITBS for Depression
Repetitive TMS (rTMS) is a well-established method for modulating brain activity. Through successive stimulations in the form of magnetic fields, it is possible to modify the sensitivity of neurons in the brain, also known as…
- Trial name
- NCT06464445
- Testing
- Monophasic iTBS, Biphasic iTBS, Monophasic-Long iTBS
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Healthy
MPFC Theta Burst Stimulation as a Tool to Affect Rational Decision Making
This is a study to investigate if a device that temporarily changes brain activity (repetitive transcranial magnetic stimulation, rTMS) might be used to change how healthy participants make decisions.
- Trial name
- NCT05917002
- Testing
- Real TBS to mPFC
- Volunteers
- healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Healthy Young Adults
iTBS Effect on M1 Plasticity, Blood Glucose, and Cardiovascular Response
Transcranial magnetic stimulation is a medical device that can alter motor cortical (M1) excitability through the scalp via various protocols.
- Trial name
- NCT06043076
- Testing
- TMS
- Where
- Malaysia
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Universiti Putra Malaysia
Concussion, Mild
Non-invasive Brain Stimulation and Injury Risk Biomechanics
The goal of this clinical trial is to test the effects of repetitive transcranial magnetic stimulation (theta burst stimulation) on movement biomechanics (jump landing) among individuals with and without a concussion history.
- Trial name
- NCT06093295
- Testing
- Repetitive Transcranial Magnetic Stimulation (Theta Burst Stimulation)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Georgia
Reading, Language
Timing and Facilitation Effects of Theta-Burst Stimulation in the Reading and Language Networks
The purpose of this study is to understand how transcranial magnetic stimulation affects how quickly, easily, and accurately a person read.
- Conditions
- Reading, Language, Control Subjects
- Trial name
- TAFE (NCT06608680)
- Testing
- iTBS, cTBS
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Georgia State University
Alzheimer Disease, Early Onset
Theta-burst Stimulation on Cognitive Function in the Patients With Young-onset Alzheimer's Disease Dementia
Young-onset dementia (YOD) is a devastating condition, and it produces substantial psychosocial impacts on individual's functioning and family's care burden. Alzheimer's disease (AD) dementia is the most common type in YOD.
- Trial name
- NCT04042532
- Testing
- Theta-burst stimulation (TBS)
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Social Cognition in Patients With Schizophrenia
Treating Social Cognition With Theta Burst Stimulation; a Pilot Sudy
The purpose of the study is to test a new treatment of social cognition deficits in patients with schizophrenia or schizoaffective disorder by transcranial magnetic stimulation (theta-burst).
- Trial name
- PilotTMS-COG (NCT02440867)
- Testing
- Active TBS
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Depression Minor
Probing Homeostatic Plasticity With Priming Theta-burst Stimulation of the Dorsolateral Prefrontal Cortex
Priming stimulation is a highly promising tool to boost the beneficial effects of therapeutic repetitive transcranial magnetic stimulation (rTMS) in psychiatry.
- Trial name
- NCT04031105
- Testing
- Theta-burst stimulation (TBS)
- Where
- Hong Kong
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Dr Georg Kranz
Major Depressive Disorder
The Utility of Concurrent TBS/fNIRS for Antidepressant Treatment Optimization
Repetitive transcranial magnetic stimulation (rTMS) with theta bursts (i.e. TBS) of the dorsolateral prefrontal cortex (DLPFC) is an innovative treatment for major depressive disorder (MDD). Indeed, the U. S.
- Trial name
- NCT04526002
- Testing
- Theta-burst stimulation (TBS)
- Where
- Hong Kong
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Dr Georg Kranz