Clinical trials: Thigh Injury
Amputation, Prosthesis User
Effects of Microprocessor-controlled Prosthetic Knees on Fall-related Health Outcomes in Limited Community Ambulators
The goal of this study is to find out if using microprocessor-controlled prosthetic knees (MPKs), prosthetic knees with a built-in computer, improves health outcomes related to falls in adults who use above-knee prostheses.
- Conditions
- Amputation, Prosthesis User, Amputation; Traumatic, Leg: Thigh, Between Hip and Knee, Limb; Absence, Congenital, Lower
- Trial name
- NCT06937242
- Testing
- Ottobock C-Leg 4 Microprocessor Knee, Ottobock Kenevo
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Hanger Institute for Clinical Research and Education, LLC
Atrophy, Disuse, Muscle Atrophy
Molecular Mechanisms Underlying Anabolic Resistance to Protein Intake During Muscle Disuse
This study will characterize intramuscular molecular mechanisms underlying anabolic resistance to protein ingestion during muscle disuse.
- Conditions
- Atrophy, Disuse, Muscle Atrophy, Muscular Disorders, Atrophic, Disuse Atrophy
- Trial name
- NCT06228742
- Testing
- Unilateral leg immobilization, Contralateral active leg
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- United States Army Research Institute of Environmental Medicine
Gluteal Tendinitis, Greater Trochanteric Pain Syndrome
Exercise and Patient Education for Patients With Lateral Hip Pain
This prospective cohort trial will investigate a progressive exercise protocol and patient education for patients with hip abductor tendon pathology.
- Conditions
- Gluteal Tendinitis, Greater Trochanteric Pain Syndrome, Hip and Thigh Injury, Rupture of Hip Abductor Tendon (Disorder)
- Trial name
- NCT06418217
- Testing
- Exercise and Patient Education
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Jeppe Lange
Other and Unspecified Injury to Hip and Thigh
CONSERVE Plus Post-Approval Study (PAS)
The objective of this post-approval study is to provide scientifically valid and reliable evidence that supports claims of longer term safety and effectiveness with regard to Month 120 device survivorship rates.
- Trial name
- NCT01367899
- Where
- United States
- Volunteers
- 199 people
- Sponsor
- MicroPort Orthopedics Inc.
Sarcopenia in Elderly, Frailty
Safety and Efficacy of Isomyosamine in Reducing Inflammation and Treating Muscle Loss in Older Adults After Hip or Thigh Bone Fractures
This Phase II clinical study investigates the safety and effectiveness of a new drug, Isomyosamine, in patients with sarcopenia or frailty, conditions associated with aging and muscle weakness.
- Conditions
- Sarcopenia in Elderly, Frailty, Frailty/Sarcopenia, Frailty in Older Adults
- Trial name
- NCT06942182
- Testing
- Isomyosamine 250mg
- Volunteers
- 60 people
- Sponsor
- TNF Pharmaceuticals, Inc.
Strains Thigh
Hamstring Strain in High School Athletes
The purpose of the current study is, 1) Determine the effectiveness of injury prevention programs for prevention of hamstring muscle strains, 2) Identify how these programs impact athletes' flexibility, muscle stiffness…
- Trial name
- NCT03248011
- Testing
- Stretching, Strengthening, Neuromuscular
- Where
- United States
- Volunteers
- 196 people
- Sponsor
- Mayo Clinic
Foot Fracture, Ankle Fractures
Use of Sterile HemaClear Tourniquet Below Calf Versus Pneumatic Tourniquet at the Thigh for Ankle and Foot Surgery
This is a Randomized controlled trial evaluating the effects of the use of Sterile HemaClear Tourniquet Below Calf Versus Pneumatic Tourniquet at the Thigh for Ankle and Foot Surgery The trial will randomize 60 patients into an…
- Conditions
- Foot Fracture, Ankle Fractures, Ankle Injuries, Foot Injuries and Disorders
- Trial name
- HemaClear (NCT04818775)
- Testing
- HemaClear, Pneumatic Tourniquet
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hospital do Coracao
Knee Injuries
The Efficacy and Safety of Electronic Stimulation in Patients Who Underwent Reconstruction of the Anterior Cruciate Ligament
This study is designed to evaluate the efficacy and safety of Myospare, a non-invasive device, which is connected to the body via electrodes placed in the injured leg.
- Trial name
- NCT00312793
- Testing
- stimulation of the quadriceps muscle with Myospare
- Where
- 3 sites in Israel
- Volunteers
- 60 people
- Sponsor
- Hadassah Medical Organization
Drop Foot, Muscle Weakness
Evaluation of Usability and Human Factors in the Novus System
The Novus system intended to provide ankle dorsiflexion and knee flexion or extension in individuals with foot drop and thigh muscle weakness, following an upper motor neuron injury or disease.
- Conditions
- Drop Foot, Muscle Weakness, Motor Neuron Disease, Upper
- Trial name
- NCT02738242
- Testing
- Novus system
- Where
- Israel
- Volunteers
- 16 people
- Sponsor
- Bioness Neuromodulation
Muscle; Injury, Quadriceps (Thigh), Tendon Strain
Mechanisms of Tissue Repair After Muscle Injury and Tendon Strain
The study is a 5-week human study including 24 18-35 year old healthy men. Each participant will have muscle injury and tendon strain induced in one leg using neuromuscular electrical stimulation in conjunction with forced…
- Trial name
- NCT05809947
- Testing
- Neuromuscular electrical stimulation
- Where
- Denmark
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Bispebjerg Hospital
Anterior Cruciate Ligament Injury
Conditioning Brain Responses to Improve Thigh Muscle Function After Anterior Cruciate Ligament Reconstruction
The purpose of this study is to examine if thigh muscle weakness and the lack of muscle activation that accompanies ACL injury can be improved through a form of mental coaching and encouragement, known as operant conditioning.
- Trial name
- NCT03209531
- Testing
- Operant Conditioning, Control, Single Pulse Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Michigan
Thigh Muscle Injury, Thigh Injury
PPP Versus Corticosteroid for Thigh Muscle Injuries
The purpose of this study is to compare the number of days it takes for a sport participant to return to play between ultrasound guided intramuscular corticosteroid injections and platelet-poor plasma (PPP) injections for thigh…
- Conditions
- Thigh Muscle Injury, Thigh Injury, Musculoskeletal, Musculoskeletal Injury Trauma
- Trial name
- NCT07513142
- Testing
- Corticosteroid, Platelet Poor Plasma
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Andrews Research & Education Foundation
Muscle Strain, Lower Leg, Muscle Strained Thigh
Cellular Mechanisms Involved in Muscle Pathology
The overall purpose of this proposed study is the understanding of cellular mechanisms involved in the pathologic fatty degeneration of muscle.
- Conditions
- Muscle Strain, Lower Leg, Muscle Strained Thigh, Achilles Tendon; Laceration, Fatty Degeneration
- Trial name
- NCT05798962
- Testing
- Biopsies
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bispebjerg Hospital
Ankle Injuries
Sural Flap and Anterolateral Thigh Flap in Tissue Reconstruction Around the Ankle
The aim of the study is to evaluate the outcomes of coverage of soft tissue defects of leg and foot by modified sural flap versus anterolateral thigh flap
- Trial name
- NCT04906967
- Testing
- flaps
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Sohag University
Incisional Negative Pressure Wound Therapy
The Use of iNPWT for Management of ALT Flap Donor Site Wound
Primary closure or skin grafting of the donor site after harvest of a anterolateral thigh flap (ALT) is associated with significant morbidity.
- Trial name
- NCT04762732
- Testing
- NPWT, Traditional wound care
- Where
- Taiwan
- Volunteers
- 138 people
- Sponsor
- National Taiwan University Hospital
Injury of Hip and Thigh
Analysis of Different Hip Adductors Exercises
Groin injuries present a major problem in sports due to its high frequency, long-lasting symptoms and high risk of re-injury. The most common groin injury is the adductor strain (around two thirds of all groin injuries), while…
- Trial name
- NCT04101786
- Testing
- Hip adductors exercise variations
- Where
- Slovenia
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Primorska
Amputation, Amputation; Traumatic, Leg, Lower
Clinical Outcomes With Non-Powered vs. Powered Prosthetic Knees by K2-level Amputees
The goal of this proposed project is to gather community-based data from the K2-level Transfemoral Amputee (TFA) population to aid in evidence-based prescription of powered prosthetic knees (i.e., choosing the right device to…
- Conditions
- Amputation, Amputation; Traumatic, Leg, Lower, Limb; Absence, Congenital, Lower, Prosthesis User
- Trial name
- NCT06194838
- Testing
- Ossur Power Knee, Reboocon Intuy Knee
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Liberating Technologies, Inc.
Non-healing Wound
Effect of Lidocaine and Adrenaline Soaked Gauze Versus Normal Saline Soaked at Skin Graft Donor Site of Thigh
Investigator is studying the effects of Lidocaine and Adrenaline Soaked Gauze vs Normal Saline Soaked Gauze at Skin Graft Donor Site of Thigh.
- Trial name
- NCT04344483
- Testing
- 2% Lidocaine and 1:100,000 Adrenaline, Normal saline
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
ACL - Anterior Cruciate Ligament Rupture
Assessment of Electromyographic Activity in the Quadriceps and Hamstrings of the Operated Limb Versus the Unaffected Limb in Patients Who Have Undergone ACL Surgery, With and Without Post-operative AMI - an Exploratory Study
Traumatic injuries to the knee joint, such as an anterior cruciate ligament tear, can compromise the ability of the muscle at the front of your thigh-known as the quadriceps-to contract voluntarily, despite the anatomical…
- Trial name
- AMIMYO (NCT07659561)
- Testing
- Electromyography
- Where
- France
- Volunteers
- 40 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Amputation, Amputation; Traumatic, Leg, Lower
Clinical Outcomes With Passive MPKs vs. Powered Prosthetic Knees
The goal of this proposed project is to gather community-based data from the K4-level Transfemoral Amputee (TFA) population to aid in evidence-based prescription of powered prosthetic knees (i.e., choosing the right device to…
- Conditions
- Amputation, Amputation; Traumatic, Leg, Lower, Limb; Absence, Congenital, Lower, Prosthesis User
- Trial name
- NCT05267639
- Testing
- Power Knee
- Where
- 2 sites in United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Liberating Technologies, Inc.