Clinical trials: Thinness
Pancreatic Cancer, Cachexia; Cancer; Sarcopenia
Spatial Multi-omics and Intelligent Early Warning of Pancreatic Cancer Cachexia
The goal of this observational study is to explore the spatial multi-omics mechanism of cachexia in pancreatic cancer and construct a high-precision multimodal intelligent early warning model for its early diagnosis in…
- Trial name
- NCT07670286
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Peking Union Medical College Hospital
Chronic Heart Failure, Cachexia
Impact of Body Composition on Bisoprolol and Ramipril Pharmacokinetics in Patients With Chronic Heart Failure
The purpose of this study is to determine if cachexia and changes in body composition influence pharmacokinetics of bisoprolol and ramipril and the accuracy of equations for renal function estimation.
- Trial name
- NCT01829880
- Where
- Slovenia
- Volunteers
- 60 people
- Sponsor
- The University Clinic of Pulmonary and Allergic Diseases Golnik
Amyotrophic Lateral Sclerosis (ALS)
Olanzapine for the Treatment of Appetite Loss in Amyotrophic Lateral Sclerosis (ALS)
Amyotrophic Lateral Sclerosis (ALS) is an adult neurodegenerative disease that is caused by a selective degeneration of the motor nerve cells in the cortex and myelon.
- Trial name
- NCT00876772
- Testing
- Olanzapine
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- Charite University, Berlin, Germany
Nutrition, Growth
Impact of Diet and Nutrition on Growth and Development in Young Children
The association between nutrition in early life and its long-term health consequences has long been known. However, there is a scarcity of scientific evidence on how nutritional status affects child growth and development in…
- Conditions
- Nutrition, Growth, Development, Stunting
- Trial name
- DIGEST (NCT06018636)
- Where
- Pakistan
- Volunteers
- 832 people, healthy volunteers welcome
- Sponsor
- Khyber Medical University Peshawar
Cachexia, Depression
Computerized Questionnaires in Assessing Symptoms, Pain, Depression, and Physical Function in Patients With Metastatic and/or Advanced Locoregional Cancer
RATIONALE: A computer-based system for assessing symptoms may be effective for patients with metastatic or advanced cancer. PURPOSE: This clinical trial is studying how well computerized questionnaires work in assessing symptoms…
- Conditions
- Cachexia, Depression, Pain, Unspecified Adult Solid Tumor, Protocol Specific
- Trial name
- NCT00972634
- Testing
- computer-assisted intervention, questionnaire administration, assessment of therapy complications
- Where
- Norway
- Volunteers
- 1,051 people
- Sponsor
- Norwegian University of Science and Technology
Cancer, Cachexia
Neurobehavioural and Cognitive Changes in Cancer Cachexia (CANCOG)
The goal of this observational study is to to look for changes within the brain, and changes in body-to-brain signals in people with cancer and people who do not have cancer. The main questions it aims to answer are: 1.
- Conditions
- Cancer, Cachexia, Cachexia-Anorexia Syndrome, Appetite Loss
- Trial name
- CANCOG (NCT06112964)
- Testing
- MRI/ Functional MRI, Self-reported questionnaires, Computer based tasks
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Cambridge
Individuals With Constitutional Thinness
Clinical Trial in Constitutional Thinness
The purpose of this study is to evaluate the molecular differences between a group of Constitutionally Thin (CT) subjects and a group of controls.
- Trial name
- NCT02004821
- Testing
- Renutryl® Booster, an oral nutritional supplement in a 300 ml bottle (600 kcal, 30 g protein, 72 g carbohydrate, 21 g fat). One bottle per day during 14 days.
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Dietary Habits, Health Knowledge, Attitudes, Practices
Evaluation Nutrition Education Intervention on Pulse and Cereal Mix for Complementary Food in Southern Ethiopia
The overall purpose of the study is to evaluate nutrition education interventions to promote pulse incorporated complementary food to the wider rural community through the government system to improve maternal knowledge, attitude…
- Conditions
- Dietary Habits, Health Knowledge, Attitudes, Practices, Wasting
- Trial name
- NCT02638571
- Testing
- enhanced education on pulse use in complementary foods
- Volunteers
- 772 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Malnutrition, Child
Effectiveness of a Positive Deviance Program in Reducing Childhood Undernutrition
Globally, childhood malnutrition remains a public health concern. Malnutrition can be diverse from undernutrition to overnutrition.
- Trial name
- NCT04688515
- Testing
- Nutrition program developed using positive deviance approach
- Where
- Malaysia
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Universiti Putra Malaysia
Overweight, Obesity
Correlation of Irisin and Adipokine Levels With Body Mass Index and Risk Factors for Metabolic Syndrome in Hispanic Children
Childhood obesity is one of the most serious global public health challenges of the 21st century (Daniels et al., 2009). Mexico has the highest prevalence of obesity, (Secretaría de Salud, 2009); 34.4% of children and 35% of…
- Conditions
- Overweight, Obesity, Thinness
- Trial name
- NCT02320110
- Where
- Mexico
- Volunteers
- 40 people
- Sponsor
- Instituto Tecnologico y de Estudios Superiores de Monterey
Gynecologic Cancer, Cachexia
WB-EMS and Individualized Nutritional Support in Gynecological Cancer Patients
This study evaluates the effects of a 12-week whole-body electromyostimulation (WB-EMS) training combined with individualized nutritional support on body composition, muscle strength and function, quality of life, fatigue and…
- Trial name
- NCT03570242
- Testing
- Whole-Body Electromyostimulation (WB-EMS)
- Where
- Germany
- Volunteers
- 150 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
NSCLC, Fatigue
Safety, Efficacy and Pharmacokinetics of ALD518 in Patients With Non-Small Cell Lung Cancer-related Fatigue and Cachexia
The purpose of this study is to asses the safety and efficacy of ALD518 in patients with Non-Small Cell Lung Cancer-Related Fatigue and cachexia (weight-loss).
- Conditions
- NSCLC, Fatigue, Cachexia
- Trial name
- NCT00866970
- Testing
- ALD518, Infusion of 0.9% Saline without ALD518
- Where
- 43 sites in Australia, Canada and 7 more
- Volunteers
- 124 people
- Sponsor
- CSL Behring
Cachexia, Weight Loss
The Effects of a 12 Week Home-based Exercise Intervention on Physical Performance in Patients With Cancers of the Gastrointestinal Tract With Pre- Cachexia or Cachexia
The main purpose of this research study is to determine if exercise improve or worsen cachexia.
- Conditions
- Cachexia, Weight Loss, Gastrointestinal Cancer
- Trial name
- NCT04802486
- Testing
- EXCAP©®
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Rochester
Epithelial Ovarian Cancer
Vitamin D and Pre Cachexia and Cancer Cachexia in Epithelial Ovarian Cancer
Several ex vivo, in vitro, and observational studies on various type of cancer shown positive effect of vitamin D. Vitamin D has widely known as immunomodulator property in various diseases.
- Trial name
- VitD (NCT04864431)
- Testing
- Vitamin D
- Where
- 3 sites in Indonesia
- Volunteers
- 54 people
- Sponsor
- Universitas Indonesia
Stunting, Severe Acute Malnutrition
Changes in Nerve Electro Physiologic Properties in Children Before and After Correction of Malnutrition
The goal of this clinical trail study is to measure neurophysiologic parameters to assess the effect of malnutrition on the peripheral nervous system and their response to treatment in three categories (SAM, severe wasting, and…
- Conditions
- Stunting, Severe Acute Malnutrition, Wasting
- Trial name
- NCT05891457
- Testing
- Nutritional Intervention
- Where
- Bangladesh
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Anorexia, Cachexia
A Study of Different Doses of Megestrol Acetate in Patients With AIDS Who Have Anorexia and Malnutrition
To compare the effects of megestrol acetate and placebo on body weight, anorexia, cachexia, calorie intake, and nutritional parameters of patients with a confirmed diagnosis of AIDS.
- Conditions
- Anorexia, Cachexia, HIV Infections
- Trial name
- NCT00002300
- Testing
- Megestrol acetate
- Where
- 15 sites in United States
- Sponsor
- Bristol-Myers Squibb
Congenital Heart Defects, Underweight
Nutrition In Preoperative Pediatric Congenital Heart Disease
Introduction: The use of a nutritional protocols provides the standardization of assessment procedures and the optimization of nutritional status recovery of pre-surgical infants with Congenital Heart Disease (CHD).
- Trial name
- NCT05457712
- Testing
- protocol, Control
- Volunteers
- 118 people
- Sponsor
- Instituto de Cardiologia do Rio Grande do Sul
Pancreatic Neoplasms, Pancreatic Cancer
Evaluating Weight Stability of Pancreatic Cancer Cachexia Patients
Eligible patients will have a diagnosis of both pancreatic adenocarcinoma and cachexia defined as greater than 5% unintentional weight loss within 6 months prior to screening visit.
- Conditions
- Pancreatic Neoplasms, Pancreatic Cancer, Cachexia, Weight Loss
- Trial name
- PanCax (NCT02400398)
- Testing
- Tube feeding
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Andrew Hendifar, MD
Constitutional Thinness
Energy Expenditure and Neuromuscular Function in Young Adult Women With a Naturally Thin Build (LeanErgy)
People with a low BMI (<17.5) are most often considered to have anorexia nervosa (AN). However, recent literature suggests that there is a category of individuals with the same low BMI who do not meet the diagnostic criteria for…
- Trial name
- LeanErgy (NCT07233109)
- Testing
- Evaluation of the maximum oxidation point of lipids, Evaluation of the energy cost of walking, Neuro-muscular assessments
- Where
- France
- Volunteers
- 36 people
- Sponsor
- Centre Hospitalier Emile Roux
Neoplasms Pancreatic, Cachexia; Cancer
The Effect of Cannabis in Pancreatic Cancer
Cannabinoids are known to increase appetite, but THC components have psychogenic properties too. CBD is the main component in the plant, and have only minimal psychogenic effects.
- Conditions
- Neoplasms Pancreatic, Cachexia; Cancer, Cannabis, Appetite Loss
- Trial name
- NCT03245658
- Testing
- THC and CBD Mixture
- Where
- Denmark
- Sponsor
- Jens Rikardt Andersen