Clinical trials: Third Molar
Decay, Dental, Impacted Third Molar Tooth
Risk Factors for Distal Caries of Second Molars Adjacent to Mandibular Impacted Third Molars
Distal surfaces of second molars adjacent to wisdom teeth are always at risk for caries and external root resorption. The incidence of caries is high, especially in partially impacted third molars in mesioangular and horizontal…
- Trial name
- NCT06017570
- Testing
- Radiologic examination on orthopantomogram, Clinical examination after surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 639 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Impacted Third Molar Tooth
Evalution of the Effects of PRP and LLLT on Postoperative Complications and Wound Healing After Impacted Third Molar
The aim of the study was to compare the possible effects of platelet-rich plasma (PRP) and low-level laser (BIOLASE) on postoperative complications after extraction of impacted mandibular wisdom teeth.
- Trial name
- NCT06836570
- Testing
- Platalet Rich Plasma, Low Level Laser Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
Pre-emptive Analgesia in Different Psycho-emotional Status Patients
Pre-emptive Analgesia Effect in Different Psycho-emotional Status Patients During Lower Third Molar Surgical Extractions
To increase the effectiveness of pain control, it is recommended to use drugs before the pain onset, therefore the pre-emptive analgesia method is considered as a method, which allows decreasing the post-operative pain to…
- Trial name
- NCT04202224
- Testing
- Ibuprofen 400 mg and Acetaminophen 500 mg, Glucose, No drug
- Where
- Lithuania
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Lithuanian University of Health Sciences
Molar, Third, Pain
Influence of CYP2C9 Genotype on Clinical Efficacy of Tenoxicam
The goal of this study is to evaluate the different gene haplotypes for the clinical efficacy of tenoxicam after third lower molar surgery for pain, edema and trismus, adverse reactions, need of rescue medication, patient…
- Trial name
- NCT04182191
- Testing
- Tenoxicam
- Where
- Brazil
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Platelet-rich Fibrin
Effect of Platelet-rich Fibrin on Soft Tissue, Periodontal Pocket Healing and Alveolar Bone Height After Third Molar Surgery
A Randomized, controlled clinical trial and split-mouth design was performed to assess and compare the effect of platelet-rich fibrin (PRF) on soft tissue healing, periodontal pocket depth and alveolar bone height distal to…
- Trial name
- NCT05866965
- Testing
- PRF, standard third molar surgical removal
- Where
- Vietnam
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Lam Cu Phong
Impacted Third Molar Tooth, Impacted Tooth
Comparing OHRQoL: One or Two Sessions for Wisdom Teeth Removal
This single-center prospective cohort study includes patients aged 18-30 years aimed to compare the effects of bilateral extraction of wisdom teeth at a single appointment (Group A) versus two separate appointments (Group B) on…
- Trial name
- NCT05820867
- Testing
- Single-Session Bilateral Mandibular Third Molar Extraction, Two-Session Bilateral Mandibular Third Molar Extraction
- Where
- Turkey (Türkiye)
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Marmara University
Impacted Third Molar Tooth
Clinical Efficacy of a New Piezoelectric Technique for Wisdom Teeth Extraction
the aim of this randomized controlled clinical study is to evaluate the efficacy of a new piezoelectric technique for wisdom teeth extraction without using manual tools versus the conventional one.Patients referred to the…
- Trial name
- NCT03619460
- Testing
- piezoelectric extraction, conventional extraction
- Where
- Italy
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera di Bolzano
To Control Pain After Third Molar Surgery
Comparative Analgesic Effects of Paracetamol/Codeine and Ibuprofen on Pain After Third Molar Surgery
To compare analgesic effects of preoperative administration of paracetamol 500 milligram plus codeine 30 milligram in single-tablet and effervescent formulation to ibuprofen 400 milligram, and placebo in the management of…
- Trial name
- NCT04730297
- Testing
- paracetamol 500 mg plus codeine 30 mg preoperative administration, ibuprofen 400 mg preoperative administration
- Where
- Italy
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza
Wisdom Tooth, Dental Impaction
Efficacy and Safety of Articaine and Lidocaine in Extraction of Wisdom Teeth of Upper and Lower Jaws
Local anesthesia drugs and anesthesia technique play an imperative role in dental treatment. The purpose of this study was to compare the efficacy and safety of different dental local anesthetics drugs and brands in clinical use…
- Trial name
- NCT05804630
- Testing
- Different dental anesthetic agents during wisdom tooth surgery (Orabloc®, Octocaine®, and Xylestesin-A®)
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Third Molar Impaction
The Effect of Different Treatment Modalities of Class II Malocclusion on Upper Third Molars.
What is the effect of the different treatment modalities (distalization versus upper premolar extraction) of class II malocclusion on the position, inclination and incidence of impaction of the upper third molars?
- Trial name
- NCT06098885
- Testing
- extraction orthodontic treatment
- Where
- Egypt
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Cairo University
Oral Complication
Effect of CGF on Postoperative Pain After Third Molar Surgery
The purpose of this study is to evaluate the effects of concentrated growth factor (CGF) on pain after bilateral impacted third molar surgery and to determine its contribution to the healing process.
- Trial name
- NCT06918327
- Testing
- Concentrated Growth Factor, non-CGF
- Where
- Turkey (Türkiye)
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Ege University
Pain, Acute, Edema
Lornoxicam Versus Etodolac After Third Molar Surgery
Our study aimed to compare the effect of lornoxicam and etodolac on postoperative pain, edema and trismus following lower third molar extraction
- Conditions
- Pain, Acute, Edema, Trismus
- Trial name
- NCT05679453
- Testing
- Lornoxicam 8 Mg Oral Tablet
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Pericoronitis
Evaluation of Photodynamic Therapy in Pericoronitis
In order to reduce the chances of systemic dissemination of the infection and the use of antibiotics, it is mandatory to test effective treatments in the initial phase of pericoronitis aiming to avoid the evolution of the…
- Trial name
- pdt (NCT03576105)
- Testing
- irrigation /sterile saline, Conventional methylene blue as photosensitizer, Methylene blue for oral use as photosensitizer
- Where
- Brazil
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Impacted Third Molar Tooth
Effectiveness of Diclofenac and Its Association to Codeine After Lower Third Molar Extraction.
It will be evaluated the clinical efficacy of Diclofenac 50mg (NSAID) compared to its association with Codeine 50mg (opioid) administered in 50 patients requiring extraction of two third molars.
- Trial name
- NCT02547896
- Testing
- Codeine + Diclofenac, Diclofenac
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Postsurgical Pain, Third Molar Extraction
Efficacy and Safety of APSCTC for the Treatment of Postsurgical Pain Due to Third Molar Extraction
The purpose of this study is to evaluate the efficacy of APSCTC compared to two active drugs in acute pain relief.
- Trial name
- CARLOTA (NCT04647435)
- Testing
- APSCTC, Toragesic®, Tramal®
- Where
- Brazil
- Volunteers
- 396 people, healthy volunteers welcome
- Sponsor
- Apsen Farmaceutica S.A.
Dental Pain
Study of Naproxen Capsules to Treat Dental Pain
The purpose of the study is to determine whether Naproxen Test Formulation Capsules are safe and effective for the treatment of dental pain.
- Trial name
- NCT01229228
- Testing
- Naproxen Test, Naprosyn
- Where
- United States
- Volunteers
- 254 people, healthy volunteers welcome
- Sponsor
- Iroko Pharmaceuticals, LLC
Oral Complication
Effect of Piezoelectric Surgery on Pain, Comfort, and Patient Satisfaction in Third Molar Surgery
The purpose of this study is to compare the effects of piezoelectric surgery on postoperative pain, comfort and patient satisfaction with conventional bur method applied in surgical extraction of impacted mandibular third molars.
- Trial name
- NCT06971653
- Testing
- conventional surgery, piezoelectric surgery
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ege University
Surgery
Analgesic Effect of Ibuprofen, Paracetamol (Acetaminophen), and Paracetamol (Acetaminophen) Plus Codeine on Acute Pain
The purpose of this placebo controlled clinical trial is to evaluate the dose response relationship of ibuprofen in doses from 400 mg to 800 mg and paracetamol (acetaminophen)in doses from 500 mg to 1000 mg compared with…
- Trial name
- NCT00699114
- Testing
- Ibuprofen 400 mg, Ibuprofen 600 mg, Ibuprofen 800 mg
- Where
- Norway
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Ullevaal University Hospital
Pain, Infection
Safety of Coronectomy vs Excision of Wisdom Teeth
The purpose of this study is to compare the surgical complications and neurosensory disturbance of coronectomy and conventional excision of wisdom teeth with roots in close proximity to inferior alveolar nerve.
- Conditions
- Pain, Infection, Alveolar Nerve Injury
- Trial name
- coronrct (NCT00752284)
- Testing
- Coronectomy, Total Excision
- Where
- China
- Volunteers
- 349 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
The Application of Hyaluronic Acid on Teeth Bone Healing. Hyaluronic Acid Which is Widely Used in Medicine for Joint, Eye Care, Wound Healing
Effect of Injectable Hyaluronic Acid (HYADENT BG (HA)) on Bone Healing in Extraction Sockets
Complications such as postoperative pain and delayed socket healing are relatively common following surgical extraction of mandibular third molars.
- Trial name
- NCT07318298
- Testing
- Surgical extraction of wisdom teeth, bone biobsy
- Where
- Jordan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology