Clinical trials: Third Molar
Pain, Dry Socket
Ozone Oil-based Gel and CHX Gel After Lower Third Molar Removal
Overall, 100 patients of both genders were included in the study, with indication of surgical extraction of lower third molar, positioned similarly after being clinically and radiographically checked by X-ray and…
- Trial name
- NCT07549672
- Testing
- Ozone Oil-based Gel
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Cairo University
Anxiety and Fear
Emotional and Oral Characteristics of Patients That Attend a Dental Consultation for the Extraction of Third Molars
Analyze the level of anxiety, hemodynamic parameters, oral status, and satisfaction among patients undergoing third molar extraction, we will assess those who attend the Master of Oral Medicine, Surgery, and Implantology program…
- Trial name
- NCT06388265
- Testing
- Trifold information
- Where
- Spain
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- University of Barcelona
Impacted Mandibular Third Molar Extraction, Dental Anxiety
Effects of Preoperative Information Formats in Third Molar Surgery
This study evaluates whether physician-guided visual information provided before impacted mandibular third molar surgery can improve hemodynamic stability during the perioperative period.
- Trial name
- NCT07484334
- Testing
- Standard Verbal Information, Real Surgical Video Information, 3D Animation Video Information
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Recep Tayyip Erdogan University
Autotransplantation of Wisdom Teeth, Patelet Rich Fibrin
Auto Transplantation of Wisdom Teeth
Autotransplantation emerges as a viable alternative to tooth extraction and prosthetic restoration when conventional endodontic treatments are unfeasible or contraindicated.
- Trial name
- NCT06553300
- Testing
- Autotransplantation with PRF, Autotransplatation Only
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cleveland Dental Institute
Trismus, Swelling
Comparison of Two Different Suture Knot Techniques on Post-Operative Trismus and Swelling After Impacted Third Molar Surgery
To compare the two different suture knot techniques, locked and unlocked, in terms of mean on postoperative trismus and swelling after impacted mandibular third molar surgery.
- Trial name
- Impacted molar (NCT07327762)
- Testing
- locking and non locking suture techniques, non locking suture technique
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Watim Medical & Dental College
Dental Pain
Safety and Efficacy Study of NTC-510 to Treat Pain Following Dental Surgery of Third Molars
To evaluate the efficacy of a single dose NTC-510 or NTC-510A for dental pain following third molar extraction.
- Trial name
- NCT02161354
- Testing
- NTC-510 capsules, NTC-510A Capsules
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- NanoSHIFT LLC
Third Molar
Does Post-operative Rinsing With a Monoject Syringe Result in as Much Post-operative Pain After Surgical Removal of Lower Impact Third Molars as no Post-operative Rinsing: a Randomized Controlled Equivalence Trial
Many authors have advocated different methods of treating alveolar osteitis. Despite many years of research, however, little progress has been made and so a study with large enough sample and standard outcome measures is…
- Trial name
- RITOR (NCT05860686)
- Testing
- Monoject syringe
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Isala
Post-operative Pain, Acute, Pain Threshold
Cold Press Test and Post Operative Pain Relationship
The goal of this clinical trial is to investigate whether it is possible to get a preliminary idea about the postoperative pain in the patient with the results of a practical cold press test applied to American Society of…
- Trial name
- NCT05904873
- Testing
- Mandibular Third Molar Surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sinem Büşra Kıraç Can
Alveolar Osteitis
The Effect of Post-extraction Collagen Sponge Application on Alveolar Osteitis
The goal of this randomized controlled trial is to compare pain, mouth opening, and alveolar osteitis following surgical extraction of bilateral symmetrical impacted lower third molars using two types of wound closures.
- Trial name
- NCT05850650
- Testing
- Application of a collagen sponge after surgical extraction of impacted 3rd molar, No collagen sponge application after surgical extraction of impacted 3rd molar
- Where
- Saudi Arabia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Riyadh Colleges of Dentistry and Pharmacy
Impacted Third Molar Tooth, Postoperative Pain Control
Oral Bromelain After Bilateral Mandibular Third Molar Surgery
The goal of this clinical trial is to learn whether oral bromelain, a pineapple-derived enzyme supplement, reduces facial swelling, limited mouth opening (trismus), and pain after surgical removal of impacted lower wisdom teeth…
- Conditions
- Impacted Third Molar Tooth, Postoperative Pain Control, Trismus, Postoperative Swelling
- Trial name
- NCT07894913
- Testing
- Bromelain, Standard postoperative medication
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Istanbul Kent University
Impacted Mandibular Third Molar, Alveolar Bone Loss
Healing of Mandibular Third Molar Extraction Sockets Using Platelet Concentrates and Photobiomodulation
Surgical removal of impacted mandibular third molars is a common procedure that may be associated with postoperative pain, swelling, limited mouth opening, and delayed bone healing.
- Conditions
- Impacted Mandibular Third Molar, Alveolar Bone Loss, Impacted Mandibular Third Molar Extraction
- Trial name
- NCT07324213
- Testing
- Mandibular Third Molar Extraction With Primary Wound Closure, Autologous Platelet Concentrates, Photobiomodulation
- Where
- Poland
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Medical Innovation Center Wroclaw
Wisdom Teeth, Oral Surgery
Microbial Growth in the Suture Thread, After Application of Different Antiseptic Gels in Mandibular Third Molars Extraction
This is a randomized clinical trial in which investigators will compare the antimicrobial effect and inducer of cicatrization as well as the degree of postoperative pain in patients who are extracted the lower third molars.
- Conditions
- Wisdom Teeth, Oral Surgery, Third Molar Surgery, Bioadhesive Gel
- Trial name
- NCT03188289
- Testing
- Clorhexidine gel, Clorhexidine-Chitosan gel, Hyaluronic Acid gel
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Santiago de Compostela
Periodontal Defect
Effect of Collagen Membranes on Distal Periodontal Healing of Second Molars After Impacted Mandibular Third Molar Surgery.
Impacted mandibular third molars can cause various complications to the adjacent second molars, such as dental caries, periodontitis, or root resorption. These complications often progress silently and asymptomatically.
- Trial name
- NCT07114523
- Testing
- collagen membrane, third molar surgery
- Where
- Vietnam
- Volunteers
- 20 people
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Trismus, Edema
Etodalac, Etoricoxib and Dexamethasone for Prevention of Pain ,Swelling and Trismus Following Third Molar Surgery
The purpose of this study is to determine whether Etodalac, Etoricoxib and Dexamethasone are effective for Prevention of Pain ,Swelling and Trismus Following Third Molar Surgery
- Conditions
- Trismus, Edema, Pain
- Trial name
- NCT00793052
- Testing
- Etodalac, Etoricoxib and Dexamethasone
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Oral Health
Effect of Hypochlorous Acid-containing Mouthwash on Healing After Impacted Wisdom Tooth Surgery
INTRODUCTION: Local chemotherapeutic agents are used to reduce inflammation after impacted tooth extraction and to minimize possible complications, as well as to increase patient comfort.
- Trial name
- Mouthwash (NCT06920485)
- Testing
- Third molar surgery, Pain Medicine, Wound healing
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Impacted Lower Third Molar, Alveolar Bone Regeneration Following Odontectomy
Evaluation of the Use of CGF Based Sticky Bone Packed in Fresh Odontectomy Site of Impacted Lower 3rd Molars
This clinical study aims to evaluate the effectiveness of Concentrated Growth Factor (CGF)-based sticky bone in enhancing bone healing after surgical removal of impacted mandibular third molars.
- Conditions
- Impacted Lower Third Molar, Alveolar Bone Regeneration Following Odontectomy, Postoperative Pain Management in Oral Surgery, Concentrated Growth Factor for Extraction Socket Healing
- Trial name
- CGF (NCT07517835)
- Testing
- Concentrated growth factors
- Volunteers
- 10 people
- Sponsor
- Cairo University
Anxiety, Dental
Virtual Reality Technology on Pain Perception and Anxiety Levels in Adolescents and Young Adults During Third Molar Germ Avulsion Surgery (VIDAMO)
For a long time, the fear of the dental surgeon has been the main reason why a percentage of the population avoids regular consultation.
- Trial name
- VIDAMO (NCT04609956)
- Testing
- Virtual reality, Standard
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Impacted Mandibular Third Molar Extraction, Postoperative Pain Control
Evaluation of Corticosteroid Administration Following Impacted Third Molar Surgery Using 3-Dimensional Facial Analysis
The purpose of this prospective, randomized, controlled, single-blind clinical trial is to compare the efficacy of local submucosal administration of dexamethasone versus methylprednisolone on postoperative morbidity following…
- Conditions
- Impacted Mandibular Third Molar Extraction, Postoperative Pain Control, Postoperative Edema and Pain
- Trial name
- NCT07628166
- Testing
- Surgical Extraction of Impacted Mandibular Third Molar, methylprednisolone sodium succinate, Dexamethasone Sodium Phosphate Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Irfan Üstündağ
Impacted Mandibular Third Molar, Postoperative Pain
Effectiveness of Dexamethasone Injection for Reducing Pain After Third Molar Surgery
This randomized clinical trial aims to evaluate the effectiveness of dexamethasone injection in reducing postoperative pain after surgical removal of impacted mandibular third molars.
- Trial name
- DEXA-TMS (NCT07538375)
- Testing
- Dexamethasone
- Where
- Pakistan
- Volunteers
- 70 people
- Sponsor
- 28 Military Dental Centre Lahore
Third Molar Extraction Surgery, Third Molar Impaction
Difficulty, Time & M3 Surgery Outcomes
This prospective observational cohort study is designed to evaluate early postoperative complications and patient-reported satisfaction following surgical extraction of impacted mandibular third molars under local anesthesia in…
- Conditions
- Third Molar Extraction Surgery, Third Molar Impaction, Satisfaction Survey
- Trial name
- NCT07296172
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Bahçeşehir University