Clinical trials: Third Molar
Anesthesia, Local
Bupivacaine Supplementation For Postoperative Pain Control In Surgical Removal Of Mandibular Third Molars
Control of postoperative pain is a foremost goal in achieving a satisfactory postoperative recovery. Surgical removal of lower third molars is accompanied by postoperative pain that is at its peak in the first 12 hours.
- Trial name
- NCT02353676
- Testing
- Bupivacaine, SALINE
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Cosmozone Dental Clinic
Dental Anxiety, Postoperative Pain
Effect of Alpha-Band Binaural Beats on Stress and Recovery in Third Molar Surgery
Preoperative anxiety and loud equipment noises, such as dental drills, create significant stress and autonomic fluctuations in patients undergoing oral surgery.
- Conditions
- Dental Anxiety, Postoperative Pain, Impacted Tooth, Binaural Beats
- Trial name
- NCT07881640
- Testing
- 10 Hz Alpha-Band Binaural Beats Track, Active Noise Cancellation (ANC)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Alperen Kalyoncu
Dental Anxiety, Impacted Third Molar Tooth
Three Anxiolytic Drugs Used in Third Molar Surgery
This study was to compare the effectiveness of three drugs (Passiflora incarnata, Erythrina mulungum, Midazolam) in controlling anxiety in patients undergoing bilateral extraction of asymptomatic, impacted mandibular third molars.
- Trial name
- NCT02065843
- Testing
- Mulungu, Passiflora incarnata, midazolam
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Sergipe
Anxiety
Comparative Study of Hemodynamic Changes Caused by Diazepam and Midazolam During Third Molar Surgery
Objective: The aim of the present study was to compare hemodynamic changes using 7.5 mg of midazolam and 10.0 mg of diazepam during the surgical removal of symmetrically positioned third molars.
- Trial name
- NCT02177955
- Testing
- 7.5 mg Midazolam, 10 mg diazepam
- Where
- Brazil
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Jimmy Barbalho
Edema, Postoperative Pain
Negative Pressure Wound Therapy in Oral Surgery
Inflammatory complications following the surgical removal of third molars remain a common and unavoidable challenge. These complications significantly impact patients' quality of life, prompting the development of numerous…
- Conditions
- Edema, Postoperative Pain, Postoperative Complications
- Trial name
- NCT06758258
- Testing
- Negative Pressure Wound Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Pain (Visceral, Somatic, or Neuropathic)
Postoperative Pain and Swelling After Flap vsFlapless Technique For Mandibular Third Molar Surgery
This randomized controlled trial evaluates postoperative pain and facial swelling following surgical removal of partially impacted mandibular third molars using flap versus flapless techniques.
- Trial name
- NCT07247929
- Testing
- flap technqiue for mandibular third molar extraction Arm A, flapless technquie arm b
- Where
- Pakistan
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Watim Medical & Dental College
Postoperative Complications
Effect of Probiotics on Pain and Oral Wound Healing After Third Molar Surgery
The aim of this research is to study the effect of probiotic supplements (Lactobacillus reuteri) on post-surgical complications and oral wound healing after extraction of impacted third molars.
- Trial name
- PROVIS (NCT02572531)
- Testing
- L. reuteri DSM 17938/ATCC PTA
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Decay, Dental, Impacted Third Molar Tooth
Risk Factors for Distal Caries of Second Molars Adjacent to Mandibular Impacted Third Molars
Distal surfaces of second molars adjacent to wisdom teeth are always at risk for caries and external root resorption. The incidence of caries is high, especially in partially impacted third molars in mesioangular and horizontal…
- Trial name
- NCT06017570
- Testing
- Radiologic examination on orthopantomogram, Clinical examination after surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 639 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Poly(Lactide-co-glycolide) Sutures, Suture Resorption
Comparative Analysis of fast-and Slow-absorbable Poly(Lactose-co-glycolide) Sutures in Oral Surgery: a Randomized Controlled Trial.
This study aims to compare slow-resorbing and fast-resorbing sutures used after the surgical extraction of lower third molars. Sutures are routinely placed after wisdom tooth removal to promote hemostasis.
- Conditions
- Poly(Lactide-co-glycolide) Sutures, Suture Resorption, Third Molar Surgery
- Trial name
- NCT07498361
- Testing
- Fast absorbable sutures application, Standard absorbable sutures application
- Where
- Italy
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Padova, School of Dental Medicine
Impacted Third Molar Tooth
Adjunctive Kinesiotaping in Surgical Treatment of Impacted Mandibular Third Molars
PATIENT INFORMATION SHEET Participants are invited to take part in a clinical study involving surgical removal of an impacted lower wisdom tooth. Participation in this study is entirely voluntary.
- Trial name
- NCT07333963
- Testing
- Kinesiotaping, extraction of impacted third lower molar
- Where
- Poland
- Volunteers
- 62 people
- Sponsor
- Medical University of Silesia
Dental Anxiety, Mandibular Third Molar
Virtual Reality to Reduce Anxiety in Adults Having Lower Wisdom Tooth Surgery
This randomized controlled trial will evaluate whether immersive virtual reality can reduce anxiety in adults undergoing surgical removal of mandibular third molars under local anesthesia.
- Trial name
- NCT07853014
- Testing
- Immersive Virtual Reality (Meta Quest 3)
- Where
- Vietnam
- Volunteers
- 120 people
- Sponsor
- Hanoi Medical University
Impacted Mandibular Third Molar, Wound Healing
Adjacent Molar Outcomes After Third Molar Surgery With PRF or Collagen Sponge
This study aims to compare platelet-rich fibrin (PRF) and an absorbable collagen sponge in extraction sockets following impacted mandibular third molar removal in terms of postoperative clinical healing and periodontal and…
- Conditions
- Impacted Mandibular Third Molar, Wound Healing, Postoperative Pain
- Trial name
- PRFvsCOLL-3M (NCT07530068)
- Testing
- Platelet-rich fibrin (PRF), Absorbable Collagen Sponge
- Where
- Turkey (Türkiye)
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Gazi University
Tooth Impaction, Tooth Diseases
Effects of Chlorhexidine Toothpaste on Wound Healing After Impacted Tooth Extraction
In this study, the postoperative clinical and microbiologic effects of chlorhexidine toothpaste and chlorhexidine-free toothpaste with the same content were compared after bilateral mandibular impacted third molar surgery.
- Trial name
- NCT06067542
- Testing
- Surgery of impacted mandibular wisdom teeth
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
Stomatognatic, Tooth Diseases
Oral Specimen and Data Acquisition Study of Subjects Requiring Third Molar Removal
Background: The third molars (wisdom teeth) normally grow in during late adolescence or early adulthood. Many people need or choose to have these teeth removed with oral surgery.
- Conditions
- Stomatognatic, Tooth Diseases, Diseases, Tooth
- Trial name
- NCT01805869
- Where
- United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Pain, Postoperative
Preemptive Analgesia With Celecoxib for Acute Dental Pain Management
The purpose of this study is to compare the effect on postoperative pain of a single agent nonsteroidal anti-inflammatory drug (NSAID) [celecoxib plus placebo] to an NSAID combination [celecoxib plus acetaminophen] administered…
- Trial name
- NCT04790812
- Testing
- Celecoxib, Acetaminophen
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Postoperative Pain
Analgesic Preoperative/Postoperative Dexketoprofen Trometamol in Third Molar Surgery
The purpose of the present investigation is to evaluate the effectiveness of the preoperative administration of Dexketoprofen Trometamol, employing the third molar surgery model, when compared to postoperative administration of…
- Trial name
- NCT02380001
- Testing
- Dexketoprofen trometamol, Preoperative control
- Where
- Mexico
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Daniel Chavarría Bolaños
Pain
Study to Investigate the Analgesic Efficacy of a Single Dose of AZD1940
The primary aim of this study is to investigate if AZD1940 can relieve the pain induced by the surgical removal of one lower wisdom-tooth.
- Trial name
- NCT00659490
- Testing
- AZD1940, Naproxen
- Where
- United States
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Molar, Impacted Teeth
Analgesic Effects of Extraoral Ultrasound Block of Mandibular Nerve for the Extraction of Lower Third Molars
This is a study about the dynamics and effects of different types of blocks (intraoral conduction anesthesia of the alveolar nerve and extraoral US block of the mandibular nerve) for extraction of lower third molars.
- Trial name
- NCT06009302
- Testing
- US guided block of mandibular nerve, Intraoral block of lower alveolar nerve
- Where
- Croatia
- Volunteers
- 36 people
- Sponsor
- Varazdin General Hospital
Pain
Study Testing Ketamine Sublingual Wafer After Wisdom Tooth Extraction
The purpose of the study is to test two different doses of ketamine sub-lingual (under the tongue) wafer against placebo to see how effective the medication is to treat moderate to severe pain after wisdom tooth extraction.
- Trial name
- NCT02356965
- Testing
- Ketamine
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- iX Biopharma Ltd.
Impacted Mandibular Third Molar
Cyanoacrylate Adhesive in Impacted Mandibular Third Molars Surgery
The goal of this randomized clinical trial is to evaluate whether cyanoacrylate tissue adhesive can improve postoperative outcomes compared with conventional silk sutures in patients undergoing surgical removal of impacted…
- Trial name
- NCT07445724
- Testing
- cyanoacrylate tissue adhesive, Silk Sutures
- Where
- 2 sites in Vietnam
- Volunteers
- 23 people
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City