Clinical trials: Third Molar
Third Molar Extraction, Piezoelectric Technique
Piezoelectric and Conventional Rotary Techniques in Third Molar Surgery: Postoperative Outcomes and Quality of Life
This study is a prospective, randomized clinical trial comparing recovery after the surgical removal of impacted lower wisdom teeth. The aim is to evaluate swelling, pain, mouth opening, and quality of life after surgery.
- Trial name
- NCT07185620
- Testing
- Third molar surgery with piezoelectric system, Third molar surgery with Conventional Rotary System
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Izzet Acikan
Paresthesia and Hypoesthesia
Vitamin B Complex for Inferior Alveolar Nerve Paresthesia Recovery
Why is this study being done? Paresthesia is a change in sensation that can cause numbness, tingling, or loss of feeling in a part of the body.
- Trial name
- NCT07592897
- Testing
- Vitamin B Complex
- Volunteers
- 50 people
- Sponsor
- University of Sao Paulo
Trismus, Edema
Impact of Preemptive Intravenous Ibuprofen on Postoperative Edema and Trismus in the Third Molar Teeth
this study was planned to investigate the antiinflammatory activity of preemptive intravenous ibuprofen on inflammatory complications such as edema and trismus after third molar tooth surgery
- Trial name
- NCT03170713
- Testing
- arveles, intrafen
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Erzincan University
Pain
Injectable Diclofenac for the Prevention of Post-operative Dental Pain
This is a prospective, randomised, double-blind, placebo-controlled, parallel group study in approximately 75 patients undergoing surgical removal of an impacted lower third molar.
- Trial name
- DP4 (NCT01706588)
- Testing
- Diclofenac sodium
- Where
- United Kingdom
- Volunteers
- 75 people
- Sponsor
- IBSA Institut Biochimique SA
Impacted Third Molar Tooth
Evaluation of the Effects of Irrigation of the Extraction Socket With Rifamycine
Removal of impacted lower third molar teeth is one of the most common oral surgical procedures, and these operations often lead to various complications in patients.
- Trial name
- NCT04349579
- Testing
- Rifamycine, Saline Solution
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Yuzuncu Yil University
Pain
Dental Pain 3rd Molar Tooth Extraction GW842166
This phase IIa (proof of concept) study will be conducted as a multi-centre study within the European Union (EU). It will be conducted to a randomised, single blind, placebo- controlled, parallel group design with a positive…
- Trial name
- NCT00444769
- Testing
- GW842166
- Where
- 3 sites in Germany, Italy and 1 more
- Volunteers
- 112 people
- Sponsor
- GlaxoSmithKline
Third Molars Extraction
Improvement of Operating Room Efficiency in Bilateral Wisdom Teeth Surgery
This study aims to assess and compare the implementation of this comprehensive program in patients undergoing bilateral third molar extraction on OR and hospital efficiency and patient experience.
- Trial name
- PREPARE (NCT06873152)
- Testing
- Control preoperative program, Advanced preoperative program
- Where
- Belgium
- Volunteers
- 130 people
- Sponsor
- Jessa Hospital
Dexamethasone Administration, Post Extraction Complication
The Effectiveness of Using a Single Post-operative Intramuscular Dexamethasone Injection on Patients with Surgical Extraction of Lower Third Molar
Evaluating the effectiveness of using a single immediate postoperative intramuscular Dexamethasone injection on pain, swelling, trismus and tissue healing in the first seven days.
- Trial name
- NCT06809855
- Testing
- Dexamethasone
- Where
- Iraq
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Yassir R. Al-khannaq
Caries, Periodontal Diseases
Third Molar: Caries, Periodontal Desease and Quality of Life
Caries and periodontal disease are chronic diseases of the oral cavity. The incidence of caries and periodontal disease can vary depending on the position of the third molar, The aim of this study was to verify possible…
- Trial name
- NCT06081816
- Testing
- carie
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Impacted Third Molar Tooth
Effect of St. John's Wort and Olive Oils on the Postoperative Complications
Surgical removal of impacted third molars is one of the most frequent procedures carried out in the oral and maxillofacial surgery clinics.
- Trial name
- NCT04373421
- Testing
- Chlorhexidine Gluconate 0.12 % Mouthwash + benzydamine hydrochloride, St. John's wort oil, Virgin olive oil
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Yuzuncu Yil University
Third Molars Extraction
Effect of Post-operative Chlorhexidine on Postoperative Pain and Complications After Surgical Removal of Mandibular Third Molars
This study aimed to assess the impact of postoperative chlorhexidine use on pain management following mandibular third molar removal In this prospective, randomized controlled trial,130 patients who underwent mandibular third…
- Trial name
- RITOR (NCT06880952)
- Testing
- Chlorhexidine Digluconate Mouthwash without Alcohol
- Where
- Netherlands
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- Isala
Tooth, Impacted
Effect of Hyaluronic Acid on Tissue Healing After Removal of Impacted Mandibular Third Molars (LM3)
Hyaluronic acid (HY) is used in dentistry to improve wound healing after oral and periodontal surgical interventions. After the application of HY, a positive effect on the wound healing of extraction sockets and periodontal…
- Trial name
- NCT04869306
- Testing
- Hyaluronic acid gel, Hyaluronic acid gel + carrier
- Where
- Austria
- Volunteers
- 102 people
- Sponsor
- Medical University of Vienna
Impacted Third Molar Tooth
Verbal and Visual Information Techniques on Anxiety in Third Molar Surgery
The aim of this study was to evaluate preoperative anxiety levels using dental anxiety scale (DAS) and the Spielberger State-Trait Anxiety Inventory (STAI).
- Trial name
- NCT03752255
- Testing
- Anxiety measurement method
- Where
- Turkey (Türkiye)
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Konya Necmettin Erbakan Üniversitesi
Tooth, Impacted
Intraosseous vs Submucosal Injection of Dexamethasone
Thirty-eight patients were randomly divided into 2 groups; the intraosseous injection group of dexamethasone (4 mg) and the submucosal injection group. All surgeries were performed by one surgeon.
- Trial name
- NCT04718077
- Testing
- Intraosseus, Submucoal
- Where
- Egypt
- Volunteers
- 38 people
- Sponsor
- Hams Hamed Abdelrahman
Impacted Third Molar Tooth
Trapezoidal Flap vs. Envelope Flap in Mandibular Third Molar Extraction.
the purpose of this study was to test the effectiveness of the envelope flap compared to trapezoidal flap in impacted mandibular third molar extractions.
- Trial name
- NCT02120131
- Where
- Italy
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Firenze and Siena, Napoli, Italy
Postsurgical Pain Due to Third Molar Extraction
An Analgesic Study to of V117957 for the Treatment of Postsurgical Pain Due to Third Molar Extraction
The primary objective of this study is to assess the analgesic properties of an oral dose of V117957 4.5 mg aqueous suspension in the third molar extraction model
- Trial name
- NCT01900795
- Testing
- V117957, Ibuprofen
- Where
- United States
- Volunteers
- 114 people
- Sponsor
- Purdue Pharma LP
Impacted Third Molar Tooth
Effects of Photobiomodulation Conditioning in Impacted Third Molars
The removal of third molars should be considered to avoid problems such as cysts and other complications. Surgical intervention with the manipulation of oral tissues has the undesirable postoperative effects of pain, trismus…
- Trial name
- NCT05344222
- Testing
- Infrared LED, Similar device - Infrared ED
- Where
- Brazil
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Pain
Evaluating Ability of HT-6184 to Reduce Inflammation and Pain After Third Molar Extraction
The goal of this clinical trial is to test the ability of HT-6184 to decrease inflammation and pain in patients after third molar removal.
- Trial name
- NCT06241742
- Testing
- HT-6184
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Halia Therapeutics, Inc.
Post Operative Swelling, Impacted Mandibular Third Molar Extraction
THE COMPARISON OF GELATIN SPONGE TO SUTURE ALONE ON POST OPERATIVE SWELLING AFTER EXTRACTION OF IMPACTED MANDIBULAR THIRD MOLAR.
This Study is designed for purpose to increase patient safety and reduce complications which occurs after mandibular 3rd molar extraction which is will increase discomfort after extraction.
- Trial name
- Gelatin Sponge (NCT07306403)
- Testing
- Gelatin Sponge Sheet, Swelling
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Watim Medical & Dental College
Pain
Efficacy and Pharmacokinetic-Pharmacodynamic Relationship of Intranasally Administered Sufentanil, Ketamine, and CT001
A randomised, double-blind, parallel-group, study comparing the analgesic effect of intranasal CT001 to intranasal sufentanil, intranasal ketamine or placebo for treatment of acute pain in adults undergoing surgical removal of an…
- Trial name
- NCT05508594
- Testing
- CT001, Sufentanil, Ketamine
- Where
- Denmark
- Volunteers
- 220 people
- Sponsor
- Cessatech A/S