Clinical trials: Thoracic Endovascular Aortic Repair
Aortic Aneurysm, Thoracic
Endovascular Repair of Descending Thoracic Aortic Aneurysms
The purpose of this study is to determine whether the system is safe and effective for the intended use of treating descending thoracic aortic aneurysms.
- Trial name
- NCT00802984
- Testing
- Endovascular thoracic aortic aneurysm repair using TALENT TAA Stent Graft System
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Stanford University
Aorta Dissection, Aorta Aneurysm
Hybrid Operation in Thoracic Aortic Dissection
The purpose of this study is to investigate the short to mid term efficacy and safety of different hybrid operations who had complex aortic lesions, such as ascending aortic/arch aneurysm, pseudo-aneurysm, Stanford Type A…
- Trial name
- NCT01500395
- Testing
- Hybrid operation
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Xijing Hospital
Thoracic Aortic Aneurysm, Thoracic Aortic Dissection
Impact of Right Atrial Occlusion on TEVAR Outcomes
Though the application of thoracic endovascular aortic repair (TEVAR) for treatment of aortic pathology is expanding, there remains a gap in the literature examining how intraoperative "reduction or elimination of aortic impulse"…
- Conditions
- Thoracic Aortic Aneurysm, Thoracic Aortic Dissection, Thoracic Aorta Abnormality
- Trial name
- NCT06786351
- Testing
- Right atrial balloon occlusion, Non right atrial balloon occlusion
- Volunteers
- 100 people
- Sponsor
- University of Calgary
Thoracic Aortic Aneurysm
STARZ-TX2 Clinical Study: Study of Thoracic Aortic Aneurysm Repair With the Zenith TX2 Endovascular Graft
The STARZ-TX2 trial (Study of Thoracic Aortic Aneurysm Repair with the Zenith TX2(R) TAA [Thoracic Aortic Aneurysm] Endovascular Graft) is a clinical trial approved by the United States Food and Drug Administration (FDA) to study…
- Trial name
- STARZ-TX2 (NCT00111176)
- Testing
- Endovascular repair, Surgical
- Where
- 41 sites in United States, Canada and 1 more
- Volunteers
- 260 people
- Sponsor
- Cook Group Incorporated
Dissection of Thoracic Aorta, Dissection of Thoracic Descending Aorta
European Multi-Centre Post-Market Registry on Thoracic Endovascular Arch Repair Using Castor™ and Cratos™
The Castor™ and Cratos™ Branched Aortic Stent Graft Systems are medical devices designed for the minimally invasive endovascular treatment of thoracic aortic pathologies in the descending aorta.
- Conditions
- Dissection of Thoracic Aorta, Dissection of Thoracic Descending Aorta, Aneurysm of Aorta, Thoracic, Penetrating Aortic Ulcers (PAUs)
- Trial name
- CEDAR (NCT07668687)
- Testing
- Implantation with Castor™ stent graft, Implantation with Cratos™ stent graft
- Where
- 4 sites in Germany, Switzerland
- Volunteers
- 100 people
- Sponsor
- Shanghai MicroPort Endovascular MedTech（Group）Co., Ltd
Aortic Aneurysm, Aortic Aneurysm, Abdominal
Safety and Efficacy of Multiple Overlapping Uncovered Stents for Pararenal Aortic Aneurysm Repair
Complex aortic aneurysms involving major branches have been difficult endovascularly. The primary purposes of this study is to evaluate the safety, feasibility, and efficacy of multiple overlapping uncovered stents in treating…
- Conditions
- Aortic Aneurysm, Aortic Aneurysm, Abdominal, Aortic Aneurysm, Thoracic, Aortic Aneurysm, Thoracoabdominal
- Trial name
- SEMPER (NCT01985906)
- Testing
- Multiple overlapping uncovered stents, Uncovered stents
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Changhai Hospital
Thoracic Aortic Aneurysm, Aortic Dissection
Biomechanical Reappraisal of Planning for Thoracic Endovascular Aortic Repair
Thoracic endovascular aortic repair (TEVAR) for disease involving the aortic arch remains complex and challenging due the angulation and tortuosity of the arch and its peculiar biomechanical environment.
- Conditions
- Thoracic Aortic Aneurysm, Aortic Dissection, Aortic Diseases
- Trial name
- MALAN (NCT03824626)
- Testing
- TEVAR patients
- Where
- Italy
- Volunteers
- 45 people
- Sponsor
- Ospedale San Donato
Blunt Injury
Thoracic Endovascular Repair Versus Open Surgery for Blunt Injury
This study aims to increase understanding of the short-term and long-term outcome of blunt aortic injury (BAI) and to discern if there is an advantage resulting from the type of operative treatment used to manage it, either the…
- Trial name
- TEVAR (NCT01852773)
- Testing
- Open repair of thoracic aorta injury, TEVAR
- Where
- United States
- Sponsor
- Scripps Health
Stroke, Silent Cerebral Infarction
Intervention With Cerebral Embolic Protection in TEVAR: Gaseous Protection
Vascular brain infarction (VBI) occurs in 67% of patients undergoing TEVAR. Overt stroke occurs in 13% of these patients and 88% of patients suffer from neurocognitive impairment.
- Conditions
- Stroke, Silent Cerebral Infarction, Neurocognitive Dysfunction, Vascular Brain Injury
- Trial name
- INTERCEPT:GP (NCT03886675)
- Testing
- CO2 flushing, Saline flushing
- Where
- United Kingdom
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Aorta Thoracic; Traumatic Rupture
Endovascular Repair for the Descending Thoracic Aorta
Most blunt aortic injuries occur in the proximal proximal descending aorta causing acute transection of this vessel. Generally, surgical repair of the ruptured segment of aorta is associated with high rates of morbidity and…
- Trial name
- ERRATA (NCT02376998)
- Testing
- Valiant™ endoluminal procedure
- Volunteers
- 20 people
- Sponsor
- University of Catanzaro
Thoracic Endovascular Aortic Repair
Reinterventions of Thoracic Endovascular Aortic Repair: a Retrospective Multicenter Cohort Study
We aimed to investigate the incidence of reinterventions in patients who underwent thoracic endovascular aortic repair (TEVAR) in multiple centers across Taiwan
- Trial name
- NCT06438653
- Testing
- No-intervenyion
- Where
- Taiwan
- Volunteers
- 600 people
- Sponsor
- National Taiwan University Hospital
Aortic Arch Aneurysm
Silent Brain Infarction After Endovascular Arch Procedures
This is the largest study to evaluate incidence and distribution of silent cerebral infarction (SBI) following endovascular repair for disease of the aortic arch.
- Trial name
- NCT04489277
- Testing
- Endovascular Arch Procedures
- Where
- 2 sites in France, Germany
- Volunteers
- 91 people
- Sponsor
- Medical University of Vienna
Aortic Dissection, Aortic Diseases
Antibiotic Prophylaxis for TEVAR
The infection rate of thoracic endovascular aortic repair (TEVAR) is unknown due to a lack of epidemiological data. The rate currently available comes from researches conducted decades ago, when open surgery was the standard of…
- Conditions
- Aortic Dissection, Aortic Diseases, Aortic Aneurysm, Thoracic, Coarctation of Aorta
- Trial name
- NCT05405790
- Testing
- thoracic endovascular aortic repair
- Where
- China
- Volunteers
- 457 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
Descending Thoracic Aortic Aneurysm
Zenith TX2® Post-market Approval Study
The Zenith TX2® Post-market Approval Study is a clinical trial approved by US FDA to further study the safety and effectiveness of the Zenith TX2® TAA Endovascular Graft in the treatment of thoracic aortic aneurysms.
- Trial name
- TX2 2PAS (NCT00813358)
- Testing
- Zenith TX2® TAA Endovascular Graft
- Where
- 25 sites in United States, Canada
- Volunteers
- 115 people
- Sponsor
- Cook Research Incorporated
Aortic Aneurysm, Abdominal, Ascending Aorta Aneurysm
Evaluation of Visceral Function Following Endovascular Aortic Aneurysm Repair Using Branched Stent- Grafts
The purpose of this study is to evaluate visceral function, after endovascular repair of thoracoabdominal aneurysms or ascending/aortic arch aneurysms.
- Conditions
- Aortic Aneurysm, Abdominal, Ascending Aorta Aneurysm, Aortic Arch Aneurysm
- Trial name
- NCT01654133
- Testing
- Endovascular repair of thoracoabdominal aortic aneurysm (TAAA) using branched stent graft, Endovascular repair of ascending/arch aortic aneurysm using branched stent graft
- Where
- United States
- Volunteers
- 770 people
- Sponsor
- University of North Carolina, Chapel Hill
Aortic Dissection, Aortic Arch Aneurysm
Clinical Study for Evaluating the Safety and Efficacy of Total Endovascular Aortic Arch Repair
Aortic disease is a kind of cardiovascular diseases with very high mortality rate and high risk of surgical treatment. At present, the surgical and endovascular treatment for diseases in the ascending aorta, descending aorta and…
- Conditions
- Aortic Dissection, Aortic Arch Aneurysm, Ulcer, Pseudoaneurysm
- Trial name
- NCT03347812
- Testing
- Endovascular Aortic Repair, Total Arch Replacement
- Where
- 4 sites in China
- Volunteers
- 400 people
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
Aortic Dissection Type B
TEAVR With False Lumen Embolization for Aortic Dissection
This multicenter, prospective, observational study aims to evaluate the efficacy and safety of thoracic endovascular aortic repair (TEVAR) combined with false lumen embolization using vascular plugs in patients with acute type B…
- Trial name
- NCT07198295
- Testing
- TEAVR with false lumen embolization
- Volunteers
- 72 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
Aortic Aneurysm, Abdominal, Aortic Aneurysm, Thoracic
TOtal tRansfemoral branCHed endovasCular tHoracoabdominal Aortic Repair Registry
The purpose of the registry is to evaluate the peri-operative, short-, and mid- outcomes of endovascular treatment of thoracoabdominal aneurysms with multibranched endografts via total transfemoral approach for visceral vessels…
- Trial name
- NCT04930172
- Testing
- Steerable introducers
- Where
- 7 sites in Italy
- Volunteers
- 100 people
- Sponsor
- IRCCS San Raffaele
Type B Aortic Dissection
LSA Reconstruction With Laser Fenestration During the TEVAR
This study aims to evaluate the feasibility, effectiveness, and safety of in-situ laser-assisted fenestration on the left subclavian artery during the procedure of thoracic artery endovascular repair
- Trial name
- LLTEVAR (NCT03845829)
- Testing
- In situ laser assisted fenestration
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Thoracic Aortic Aneurysm, Aortic Diseases
Active Thoracic Compromised Distal LANding in TEvar
Thoracic endovascular aortic repair (TEVAR) has become the mainstay of aortic intervention for descending thoracic aortic pathology.
- Trial name
- ATLANTE (NCT06882967)
- Testing
- Thoracic Endovascular Aortic Repair
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS