Clinical trials: Thoracic Epidural
Chronic Postoperative Pain, Chest Pain
The Effectiveness of Thoracal Epidural Steroid and Local Anesthetic Injection
The primary objective was to evaluate the effectiveness of thoracic interlaminar epidural injections in alleviating pain and enhancing function in patients suffering from chronic mid and/or upper back pain.
- Conditions
- Chronic Postoperative Pain, Chest Pain, Back Pain
- Trial name
- NCT06507995
- Testing
- thoracic interlaminar epidural injection
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ankara University
Post-thoracotomy Pain Syndrome
The Effect of Ultrasound Guided Superficial, Deep Serratus Plane Blocks and Thoracic Epidural in Thoracotomy
Pain after thoracotomy is known to be sever acute pain that is resulted from retraction, resection or fracture of ribs .This pain increases post operative morbidity and if not properly managed peri-operatively, chronic post…
- Trial name
- NCT04189120
- Testing
- Thoracic epidural analgesia , superficial serratus plane block and deep serratus plane block
- Where
- Egypt
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute, Egypt
Movement of Thoracic and Lumbar Skin
How Much Can the Thoracic and Lumbar Skin Slide?
The investigators want to determine how much the skin on the back can move left to right of the midline and also up and down, in subjects presenting for procedure or in healthy volunteers.
- Trial name
- NCT02105363
- Testing
- measure of skin movement on surface of the back, Measurement of skin movement on surface of back
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Post Thoracic Surgery
Intrapleural Bupivacaine for Ipsilateral Shoulder Pain After Thoracotomy
While thoracic epidural could control incisional pain after thoracotomy, an excruciating ipsilateral shoulder pain happens post thoracotomy and could affect up to 85% of thoracotomy patients.
- Trial name
- NCT03862404
- Testing
- Bupivacaine-epinephrine, Normal saline
- Where
- Canada
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Post-operative Pain, Thoracic Epidural
Dexmedetomidine and Fentanyl as Adjuvants to Thoracic Epidural
To find out if there is a benefit from adding dexmedetomidine to epidural bupivacaine as regards: Intra and postoperative opioid consumption Pain score (numerical rating scale) Hemodynamic stability, Patient satisfaction.
- Conditions
- Post-operative Pain, Thoracic Epidural, Thoracotomy Surgery
- Trial name
- adjuvants (NCT06489574)
- Testing
- thoracic epidural with dexmedetomidine in patients undergoing thoracotomy surgery, thoracic epidural with fentanyl in patients undergoing thoracotomy surgery
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Analgesia, Epidural
Neuraxial Ultrasound for Thoracic Epidural Placement
This blinded, randomized study compares standard palpation to ultrasound-assisted landmark identification of the thoracic spine for thoracic epidural catheterization.
- Trial name
- NCT02785055
- Testing
- Thoracic Epidural Placement, Bupivacaine 0.05%, Hydromorphone 0.01mg/mL
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Benaroya Research Institute
Neuropathic Pain, Chronic Pain
Post-operative Thoracic Epidural Analgesia and Incidence of Major Complications: a Large Retrospective Dual Center Experi-ence
A retrospective observational dual center study investigating side effects and major complications after thoracic epidural insertion according to local safety protocols.
- Conditions
- Neuropathic Pain, Chronic Pain, Thoracic Cancer
- Trial name
- NCT05909007
- Testing
- thoracic epidural insertion
- Where
- Greece
- Volunteers
- 1,145 people, healthy volunteers welcome
- Sponsor
- AHEPA University Hospital
Analgesia
Ultrasound Guided : Retrolaminar Block Versus Thoracic Epidural Analgesia Following Laparoscopic Cholecystectomy
The aim of this study is to evaluate analgesic effect of ultrasound-guided retrolaminar block vs ultrasound-guided thoracic epidural analgesia in pain control following laparoscopic cholecystectomy.
- Trial name
- NCT04835415
- Testing
- Bilateral retrolaminar block, Thoracic epidural analgesia
- Where
- Egypt
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Epidural Analgesia, Mechanical Ventilation
Effects of Thoracic Epidural Analgesia in Geriatric Patients Undergoing Open Heart Surgery
Elderly patients have a higher incidence of morbidity and mortality due to the interaction of various factors such as decreased physiological reserves, concomitant comorbidities, multiple drug use, cognitive dysfunction, and…
- Conditions
- Epidural Analgesia, Mechanical Ventilation, Postoperative Complications, Analgesia
- Trial name
- NCT04708080
- Testing
- thoracic epidural analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 640 people, healthy volunteers welcome
- Sponsor
- Karadeniz Technical University
Pain, Postoperative, Respiratory Complication
Thoracic Epidural Analgesia and Bilateral Erector Spinae Plane Block on Postoperative Pain in Open Heart Surgeries
Postoperative pain negatively effects respiratory functions in open heart surgeries. The aim of the study is to compare the effects of thoracic epidural analgesia (TEA) and erector spinae plane block (ESPB) on postoperative pain…
- Trial name
- NCT06098859
- Testing
- Thoracic epidural analgesia, Erector spinae plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Karadeniz Technical University
Surgery, Analgesia
Thoracic Epidural Analgesia vs Surgical Site Infiltration With Liposomal Bupivacaine Following Open Gynecologic Surgery
The goal of this study is to test the hypothesis that surgical site infiltration with liposomal bupivacaine (LB) is non-inferior to and more cost effective than thoracic epidural analgesia (TEA) for patients undergoing open…
- Trial name
- NCT04117074
- Testing
- Liposomal bupivacaine, Thoracic epidural analgesia (bupivacaine)
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Pain, Postoperative
Continuous Thoracic Epidural Versus Erector Spinae Plane Block for Postoperative Analgesia in Donar Hepatectomies.
Introduction Adult living related donor hepatectomy is associated with pain due to the sub-costal j-shaped incision, rib retraction using Thompson retractor, and diaphragm irritation1.
- Trial name
- NCT04151511
- Testing
- Continuous Erector Spinae Plane Block
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Shifa Clinical Research Center
Rib Fractures
Non-Inferiority Study of Erector Spinae Plane Block Compared to Thoracic Epidural in Pain Management of Rib Fractures
The purpose of this study is to compare 2 pain control treatments for people with 3 or more rib fractures.
- Trial name
- SUETHE-Ribs (NCT05069961)
- Testing
- ESPB, TEA
- Volunteers
- healthy volunteers welcome
- Sponsor
- Indiana University
Pectus Excavatum
A Comparison Trial Between PCA and Epidural Analgesia for Pectus Excavatum Repair
The aim of this study is to compare the efficacy of epidural and IV analgesia in controlling pain in patients undergoing Nuss repair of pectus excavatum.
- Trial name
- NCT02056301
- Testing
- Hydromorphone, Morphine
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Pectus Excavatum, Pain, Postoperative
Identification of Best Postoperative Analgesia Method Following a Minimally Invasive Repair of Pectus Excavatum
Pectus excavatum is the most common chest wall deformity in children, accounting for 90% of all congenital chest wall deformities. It occurs in one to eight per 1000 live births.
- Trial name
- (MIRPE) (NCT04211935)
- Testing
- Use of PCA, Use of ESB for postoperative pain control after MIRPE, Use of INC for postoperative pain control after MIRPE
- Where
- United States
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Respiration Disorders
Epidural Analgesia and Postoperative Respiratory Functions (EPAPRES)
Patients operated with posterolateral thoracotomy were enrolled. Post-operative analgesia was provided either by TEA with 0.1% bupivacaine or pethidine based intravenous analgesia (IVA) in our sample population.
- Trial name
- EPAPRES (NCT03643757)
- Testing
- Thoracic epidural analgesia, Bupivacaine
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Yedikule Training and Research Hospital
Epidural Block, Oesophageal Cancer
The Hemodynamic Effect Between Two Types of Anesthesia in Esophageal Surgery
Continuous Paravertebral block (PVB) was reported to provide less episodes of hypotension than continuous thoracic epidural block (TEB).
- Conditions
- Epidural Block, Oesophageal Cancer, Oesophagectomy
- Trial name
- HEMOBLOC (NCT03185403)
- Testing
- paravertebral block, thoracic epidural block, ropivacaine
- Where
- France
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Postoperative Retention of Urine, Postoperative Urinary Tract Infection
Day Zero Urinary Catheter Removal in Gen Thoracic Surgery Patients
Current standard of practice in study institution dictates day of surgery urinary catheter removal in general thoracic surgery patients receiving thoracic epidural analgesia.
- Trial name
- NCT01309529
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Memorial Health System
Fluid Overload, Anesthesia; Adverse Effect, Spinal and Epidural
Can Vena Cava Ultrasound Guided Volume Repletion Prevent Spinal Induced Significant Hypotension in Elective Patients?
Aim of this study is to determine whether Inferior Vena Cava analyzed by trans-thoracic echocardiography is an effective method to guide titrated fluid repletion in non critical patients, in order both to decrease post procedural…
- Conditions
- Fluid Overload, Anesthesia; Adverse Effect, Spinal and Epidural, Regional Anesthesia Morbidity
- Trial name
- NCT02271477
- Testing
- Ultrasound-guided volemic repletion
- Where
- Switzerland
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Ente Ospedaliero Cantonale, Bellinzona
Video-assisted Thoracic Surgery
Effect of the PIEB Versus CEI on the Quality of Postoperative Recovery in Patients Undergoing VATS Lobectomy
In recent years, lobectomy under VATS(Video-assisted thoracic surgery,VATS) has gradually emerged, but there is still a proportion of patients with postoperative pain that affects their postoperative recovery.
- Trial name
- NCT05930405
- Testing
- programmed intermittent epidural bolus, continuous epidural infusion
- Where
- China
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University