Clinical trials: Thoracic Surgery With One-lung Ventilation
Thoracic Surgery With One-lung Ventilation
Ultrasound vs. Auscultation and Fiberoptic Bronchoscopy for Double-Lumen Tube Placement
One-lung ventilation is frequently required in thoracic surgery and is most commonly achieved using double-lumen endobronchial tubes (DLTs).
- Trial name
- NCT07465510
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Izmir City Hospital
Mechanical Ventilation, Postoperative Pulmonary Complications (PPCs)
Flow-Controlled Ventilation to Improve Postoperative Pulmonary Outcome After Thoracic Surgery
In an international multicenter randomized clinical pilot trial, intraoperative flow-controlled ventilation (FCV) will be compared with volume-controlled ventilation (VCV) in patients scheduled for (open, video- or…
- Trial name
- PROFLOW-THORAC (NCT07623395)
- Testing
- Flow-Controlled Ventilation, Volume-Controlled Ventilation
- Where
- 7 sites in Austria, France and 2 more
- Volunteers
- 140 people
- Sponsor
- Cantonal Hospital of St. Gallen
Lung Cancer
Comparison of Emergence and Oxygenation During One-lung Ventilation With Desflurane and Propofol Anesthesia
Which is more adequate general anesthetic agent, desflurane or propofol, for emergence and recovery time, and perioperative oxygenation in lung resection surgery?
- Trial name
- NCT02324283
- Testing
- desflurane, propofol
- Where
- Japan
- Volunteers
- 80 people
- Sponsor
- Juntendo University
Lung Resection Surgery, Anesthesia General
Effect of Oxygen Administration in the Non-dependent Lung on Postoperative Complications After Lung Surgery
The purpose of this study is to analyze the effectiveness of apneic oxygenation and CPAP applied to the non-dependent lung during pulmonary resection surgery in reducing inflammatory response, ischemia-reperfusion injury, and…
- Trial name
- NCT07461779
- Testing
- Medicinal gas - oxygen (Nippon Gases 200 bar), CPAP, Oxygen therapy according to standard clinical practice
- Where
- Spain
- Volunteers
- 177 people
- Sponsor
- Francisco Andres de la Gala
Positive-Pressure Respiration, Intrinsic
Flow Controlled Ventilation in Thoracic Surgery
This trial investigates effects of individualized (by compliance guided pressure settings) flow-controlled ventilation compared to best clinical practice pressure-controlled ventilation in thoracic surgery requiring one lung…
- Trial name
- NCT04534933
- Testing
- Evone, Primus
- Where
- Austria
- Volunteers
- 46 people
- Sponsor
- Medical University Innsbruck
Thoracic Surgery With One-lung Ventilation, VExUS
Effect of VExUS Ultrasound Protocol (Venous Excess Ultrasound) on Perioperative Fluid Management, on the Incidence of Postoperative Pulmonary Complications and Postoperative Acute Kidney Injury in Patients Undergoing Thoracic Surgery
This study aims to investigate the effect of a VExUS ultrasound guided protocol of perioperative fluid management within a goal-directed therapy framework, on postoperative respiratory complications, and the occurrence of acute…
- Conditions
- Thoracic Surgery With One-lung Ventilation, VExUS, Fluid Management, Acute Kidney Injury
- Trial name
- VEXUS (NCT07258875)
- Testing
- Venous Excess Ultrasound, Standard of Care (SOC)
- Where
- Greece
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- University of Crete
Thoracic Surgery, One-lung Ventilation
Intraoperative Neuromuscular Blockade and Postoperative Atelectasis
During one-lung ventilation in thoracic surgery, the intensity of neuromuscular blockade may change the compliance and resistance of ventilated lung, thereby affecting postoperative atelectasis.
- Trial name
- NCT03503565
- Testing
- intraoperative neuromuscular blockade
- Where
- South Korea
- Volunteers
- 118 people
- Sponsor
- Kyung Hee University Hospital at Gangdong
Thoracic Surgery, Video-Assisted
A Prospective Descriptive Study of the Individualized Capnography of Both Lungs During One-lung Ventilation With Double-lumen Tube
A prospective descriptive study of the use of an individualized capnography to each lung in the context of one-lung ventilation achieved with a double-lumen tube.
- Conditions
- Thoracic Surgery, Video-Assisted, Double-Lumen Tube, Capnography
- Trial name
- EtCO2-DLT (NCT04962581)
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Laval University
One Lung Ventilation
Evaluation Of One Lung Ventilation With Ultrasound in Thorax Surgery Operations
BACKGROUND: The aim of this study is to evaluate the confirmation of double lumen tube placement with thoracic Ultrasound (USG) in thorax surgery operations with one lung ventilation.
- Trial name
- NCT06064773
- Testing
- thoracic USG
- Where
- Turkey (Türkiye)
- Volunteers
- 130 people
- Sponsor
- Dokuz Eylul University
Video-assisted Thoracic Surgery, Postoperative Atelectasis
Optimal Level of PEEP in Protective One-lung Ventilation
Protective ventilation strategy has been widely applied in the field of thoracic surgery requiring one-lung ventilation to reduce postoperative pulmonary complications.
- Conditions
- Video-assisted Thoracic Surgery, Postoperative Atelectasis, Positive End-expiratory Pressure
- Trial name
- NCT03856918
- Testing
- PEEP 3 cm of water, PEEP 6 cm of water, PEEP 9 cm of water
- Where
- South Korea
- Volunteers
- 142 people
- Sponsor
- Seoul National University Hospital
One-Lung Ventilation
Protective Ventilation With High Versus Low PEEP During One-lung Ventilation for Thoracic Surgery
One-lung ventilation (OLV) with resting of the contralateral lung may be required to allow or facilitate thoracic surgery. However, OLV can result in severe hypoxemia, requiring a mechanical ventilation approach that is able to…
- Trial name
- NCT02963025
- Testing
- PEEP level, Use of recruitment maneuvers
- Where
- 79 sites in United States, Albania and 27 more
- Volunteers
- 2,200 people
- Sponsor
- Technische Universität Dresden
Mechanical Ventilation Complication, Thoracic Surgery
The Effect of Recruitment Maneuver With Protective Ventilation During Thoracic Surgery
The purpose of this study is to determine if a recruitment maneuver combined with protective ventilatory strategy could reduce the pulmonary and systemic inflammatory responses to one-lung ventilation during thoracic surgery.
- Conditions
- Mechanical Ventilation Complication, Thoracic Surgery, Inflammation
- Trial name
- NCT01630395
- Testing
- protective ventilation, Recruitment maneuver combined with protective ventilation
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Seoul National University Hospital
Hypoxaemia During Surgery, Lung Hyperinflation
HFHO vs CPAP During Thoracic Surgery
A single institutional cross-over study design to compare between high flow humidified oxygen (HFHO) device versus conventional CPAP for non-ventilated lung during thoracic surgery.
- Trial name
- NCT03894072
- Testing
- CPAP, HFHO
- Where
- Thailand
- Volunteers
- 28 people
- Sponsor
- Mahidol University
Pulmonary Resection
Inflammatory Response Secondary Using Intravenous Anesthesia Versus Inhalation Anesthesia With Halogenated Agents
Lung ventilation required for lung resection surgery induces a proinflammatory response including cytokine production and recruitment of leukocytes and macrophages in the lung associated with postoperative complications, mainly…
- Trial name
- NCT02168751
- Testing
- propofol, Sevoflurane
- Where
- Spain
- Volunteers
- 180 people
- Sponsor
- Hospital General Universitario Gregorio Marañon
Thoracic Surgery With One-lung Ventilation, Lung Isolation
Efficacy and Safety of the Visual Bronchial Blocker for Lung Isolation Surgery
This multicenter, prospective, randomized, controlled clinical trial is initiated by the First Affiliated Hospital of Zhejiang University School of Medicine, with participation from Peking Union Medical College Hospital, the…
- Conditions
- Thoracic Surgery With One-lung Ventilation, Lung Isolation, Bronchial Blockage, Anesthesia
- Trial name
- NCT07644104
- Testing
- Visual Bronchial Blocker, Conventional Bronchial Blocker
- Where
- China
- Volunteers
- 652 people
- Sponsor
- Zhejiang University
Women, Asian
Effect of Small Double-lumen Tube on the Intubation Time of Thoracoscopic Pulmonectomy in Asian Women
The purpose of this experiment is to verify whether selecting a double-lumen tube one size smaller based on the traditional personalized method can shorten the intubation time without increasing ventilation complications when…
- Conditions
- Women, Asian, Thoracic Surgery With One-lung Ventilation
- Trial name
- NCT07097584
- Testing
- Selecting the size of a Left Double-lumen endobronchialtube one size smaller than the traditional method, Selecting the size of a Left Double-lumen endobronchialtube according to traditional methods
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Zhejiang Cancer Hospital
Thoracic Diseases
Mechanical Insufflator-exsufflator in Patients After Video-assisted Thoracoscopic Operations With One-lung Ventilation
Postoperative pulmonary complications (PPC) are a common problem in patients undergoing surgery using one-lung invasive ventilation.
- Trial name
- NCT06180148
- Testing
- Mechanical insufflator-exsufflator
- Where
- Russia
- Volunteers
- 31 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Single Lung Ventilation, Thoracic Surgery
Double-lumen Tubes (DLT) - Health Economic Study
The aim of this study is to make a health economic evaluation comparing novice physicians use of VivaSight double-lumen tube and a conventional double-lumen tube for single-lung ventilation during thoracic surgery at a teaching…
- Conditions
- Single Lung Ventilation, Thoracic Surgery, Anesthesia, Cost-effectiveness
- Trial name
- NCT03817879
- Testing
- VivaSight double-lumen tube for single-lung ventilation, Conventional double-lument tube for single-lung ventilation
- Where
- Denmark
- Volunteers
- 70 people
- Sponsor
- Ambu A/S
Hypotension, Hemodynamic Instability
The "Hypotension Prediction Index" in Patients Undergoing Lung Surgery
The "Hypotension Prediction Index (HPI)" was established by the Edwards Lifescience Company (Irvine, California, USA) and is CE certified.
- Conditions
- Hypotension, Hemodynamic Instability, Renal Failure, Myocardial Injury
- Trial name
- NCT04149314
- Testing
- HPI based hemodynamic optimization algorithm
- Where
- Germany
- Volunteers
- 142 people
- Sponsor
- University of Giessen
Thoracic Surgery With One-lung Ventilation
One-lung Ventilation: Expression of Pulmonary Inflammatory Mediators
One-lung ventilation; organ protection; volatile anesthetics One-lung ventilation has become a common procedure for thoracoscopic surgery. Two hypothesis will be tested in this study: 1.
- Trial name
- NCT00515905
- Testing
- Sevoflurane/propofol
- Where
- Switzerland
- Volunteers
- 76 people
- Sponsor
- University of Zurich