Clinical trials: Thoracic Surgical Procedures
Thoracic Surgery
The Effect of Permissive Hypercapnia on Oxygenation and Post-operative Pulmonary Complication During One-lung Ventilation
Permissive hypercapnia increased the survival rate in patients with acute respiratory distress syndrome (ARDS) who required mechanical ventilation in critical care medicine.
- Trial name
- NCT04175379
- Testing
- group 40, group 50, group 60
- Where
- South Korea
- Volunteers
- 279 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Surgical Education, Simulation-based Training
Structured Simulation Training for Laparoscopic and Thoracoscopic Skills in Thoracic Surgery Residents
This study aims to improve basic laparoscopic and thoracoscopic skills in thoracic surgery residents and rotating surgical residents through a structured simulation-based training program.
- Conditions
- Surgical Education, Simulation-based Training, Resident Training
- Trial name
- NCT07268950
- Testing
- Structured Simulation-Based Surgical Training
- Where
- Turkey (Türkiye)
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Malignant Lung Neoplasm
Video-Assisted Intervention in Improving Recovery in Patients With Cancer Undergoing Lung Surgery and Caregivers
This pilot clinical trial studies a video-assisted intervention in improving recovery of patients undergoing surgery to remove lung cancer or cancer that has spread to the lung and their caregivers.
- Trial name
- NCT02345798
- Testing
- Standard Follow-Up Care, Caregiver-Related Intervention or Procedure, Educational Intervention
- Where
- United States
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- City of Hope Medical Center
Non-small Cell Lung Cancer(NSCLC)
the"Fuzheng" Therapy of TCM to Improve the Survival Quality of Early-stage NSCLC by Intervening the CTCs
Metastasis is the leading cause of death in patients with lung cancer, and circulating tumor cells(CTCs) play a key role in the process of distant metastasis.
- Trial name
- CTC-TCM-FZ (NCT02603003)
- Testing
- JinFuKang, Cisplatin, Pemetrexed
- Volunteers
- 218 people, healthy volunteers welcome
- Sponsor
- Shanghai University of Traditional Chinese Medicine
Video-assisted Thoracoscopic Surgery
Effect of Cervical Vagal Blockade on Cough Incidence in Non-intubated Uniportal Video-assisted Thoracic Surgery
Currently, there is a trend toward non-intubated anesthesia methods for video-assisted thoracic surgery in our hospital. During the surgery, intrathoracic vagus nerve blockade is suggested for inhibit cough reflex in previous…
- Trial name
- NCT04426097
- Testing
- Cervical Vagal Blockade, Without Blockade
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University WanFang Hospital
One-Lung Ventilation, Thoracic Surgery
The Effect of Anesthesia on Cerebral Oxygenation
One-lung ventilation (OLV) may cause negative changes in the oxygenation of cerebral tissue which results in postoperative cognitive dysfunction.
- Conditions
- One-Lung Ventilation, Thoracic Surgery, Postoperative Cognitive Complications
- Trial name
- NCT04760262
- Testing
- Sevoflurane, Propofol
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Karadeniz Technical University
Lung Cancer
Efficacy Between Serratus Plane Block And Local Infiltration In Vats
Robotic video-assisted thoracoscopic surgery (VATS) is increasingly being used as it is a less invasive surgery compared to traditional methods, but the acute pain at an early stage after VATS has a major impact on perioperative…
- Trial name
- NCT03642457
- Testing
- Bupivacaine, Bupivacaine liposome
- Where
- 2 sites in United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Thoracic Surgery, Abdominal Surgery Patients
Influence of the Culture Care Program on Patient Mobility After Thoracic or Abdominal Surgery: a Mixed-methods Study
A sedentary behavior in the postoperative phase has a negative impact on recovery from various types of surgery (e.g. abdominal, pulmonary, cardiac or esophageal).
- Conditions
- Thoracic Surgery, Abdominal Surgery Patients, Hospital Mobility, Mobility Limitation
- Trial name
- CULTURECARE (NCT06893848)
- Testing
- Culture Care program
- Where
- Switzerland
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- Haute Ecole ARC Sante
Thoracic Surgery
Comparison of Bupivacaine Liposomal vs Bupivacaine Combined With Dexamethasone for Postoperative Pain in VATS
The purpose of this study, is to investigate the effectiveness of ultrasound-guided rhombic intercostal nerve block for postoperative pain control in thoracoscopic pulmonary resection with bupivacaine liposomes versus bupivacaine…
- Trial name
- NCT06392191
- Testing
- Rhombic intercostal nerve block(Received liposomal bupivacaine 93 mg and bupivacaine 25 mg diluted to 20 ml), Rhombic intercostal nerve block(Receive standard bupivacaine 105 mg diluted to 20 ml with dexamethasone 5 mg.)
- Where
- China
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Affiliated Hospital of Jiaxing University
Cough, Laryngospasm
Benefits of Exchanging a Double Lumen Tube to a Proseal Laryngeal Mask or a Single Lumen Tube After a Thoracic Surgery
The purpose of this study is to determine whether exchange of the double lumen tube before emergence with a laryngeal mask airway (Proseal) or a tracheal tube will reduce cough at emergence.
- Conditions
- Cough, Laryngospasm, Apnea, Desaturation
- Trial name
- NCT00925613
- Testing
- LMA Proseal, Tracheal tube
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Université de Montréal
Liver Cancer, Esophageal Cancer
Pre- and Post-operative TEG Indices in Patients With or Without Adenocarcinoma Undergoing Surgical Resection
The investigators hypothesize that abnormalities in thromboelastography (TEG) parameters in patients with liver, pancreas, biliary, esophageal, colorectal, and lung adenocarcinoma can serve as biomarkers for oncologic disease…
- Conditions
- Liver Cancer, Esophageal Cancer, Colorectal Cancer, Lung Adenocarcinoma
- Trial name
- TEG (NCT05517811)
- Testing
- TEG indices
- Where
- 2 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Adult Liver Carcinoma, Caregiver
Walking for Recovery From Surgery in Improving Quality of Life in Older Adults With Lung or Gastrointestinal Cancer and Their Family Caregivers
This pilot clinical trial studies how well Walking for Recovery from Surgery works in improving quality of life in older adults with lung or gastrointestinal cancer and their family caregivers.
- Conditions
- Adult Liver Carcinoma, Caregiver, Colorectal Carcinoma, Lung Carcinoma
- Trial name
- NCT03267524
- Testing
- Exercise Intervention, Quality-of-Life Assessment, Survey Administration
- Where
- United States
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- City of Hope Medical Center
Video-assisted Thoracic Surgery
Effect of the PIEB Versus CEI on the Quality of Postoperative Recovery in Patients Undergoing VATS Lobectomy
In recent years, lobectomy under VATS(Video-assisted thoracic surgery,VATS) has gradually emerged, but there is still a proportion of patients with postoperative pain that affects their postoperative recovery.
- Trial name
- NCT05930405
- Testing
- programmed intermittent epidural bolus, continuous epidural infusion
- Where
- China
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Postoperative Pulmonary Complications, Thoracic Surgery
Intermittent Positive Pressure Breathing Versus Incentive Spirometry After Thoracic Surgery
This randomized controlled pilot study will compare intermittent positive pressure breathing (IPPB) with incentive spirometry (IS) in adult patients undergoing thoracic surgery.
- Trial name
- NCT07867548
- Testing
- Intermittent Positive Pressure Breathing, Incentive Spirometry
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Fu Jen Catholic University Hospital
Analgesia, Epidural
Neuraxial Ultrasound for Thoracic Epidural Placement
This blinded, randomized study compares standard palpation to ultrasound-assisted landmark identification of the thoracic spine for thoracic epidural catheterization.
- Trial name
- NCT02785055
- Testing
- Thoracic Epidural Placement, Bupivacaine 0.05%, Hydromorphone 0.01mg/mL
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Benaroya Research Institute
Pain, Postoperative, Opioid Use
Analgesic Efficacy of Intravenous Ketamine as a Continuous Infusion vs PCA in the Management of Acute Postoperative Pain in Major Orthopedic Surgery.
The goal of this clinical trial is to determine whether treating pain after surgery with ketamine is more effective when administered intravenously as a continuous infusion or through a patient-controlled analgesia (PCA) pump.
- Conditions
- Pain, Postoperative, Opioid Use, Major Surgery
- Trial name
- NCT06774274
- Testing
- Ketamine infusion, PCA Ketamine
- Where
- Colombia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Universidad de Antioquia
Rib; Fracture
RibFix Blu Thoracic Fixation System Versus Non-surgical Treatment in Non-flail Chest Rib Fractures
This is a prospective, multi-center, observational, cohort study involving skilled cardiothoracic surgeons who are experienced in implanting the treatment of non-flail chest rib fractures and the use of RibFix Blu Thoracic…
- Trial name
- NCT05146986
- Testing
- Non surgical and Surgical
- Where
- 5 sites in Australia, South Korea
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- Zimmer Biomet
Video Laryngoscope, Double Lumen Tube Intubation
C-MAC Blade D Video Vs Macintosh Laryngoscope for Double Lumen Tube Insertion
The goal of this clinical trial is to know which type of laryngoscope is better for Double Lumen Tube (DLT) insertion, in participants undergoing elective thoracic surgeries.
- Conditions
- Video Laryngoscope, Double Lumen Tube Intubation, Elective Thoracic Surgery
- Trial name
- DLT (NCT06759038)
- Testing
- C-MAC blade D video laryngoscope, Macintosh Laryngoscope
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Shaheed Mohtarma Benazir Bhutto Institue of Trauma
Neuromuscular Blockade
The Clinical Effect of Sugammadex Sodium (Domestic) for Antagonizing Neuromuscular Blockade After Thoracic Surgery
This study aims to compare the use of sugammadex (domestic) and neostigmine for antagonism after thoracic surgery, and observe the effect of sugammadex (domestic) on neuromuscular blockade antagonism after thoracic surgery, in…
- Trial name
- NCT06334562
- Testing
- SUGAMMADEX SODIUM 100 Mg in 1 mL, Neostigmine
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Endothelial Dysfunction
Endothelial Dysfunction As A Predictor Of Perioperative Outcome
The goal of this clinical research study is to learn whether the inability of certain blood vessel cells (endothelial cells) to function properly may help researchers to predict who is at risk for complications after surgery and…
- Trial name
- NCT00384683
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center