Clinical trials: Thoracic Surgical Procedures
Thoracic Diseases, Surgery
Comparative Analysis of the Lung Inflammatory Response After Thoracic Surgery With Single or Double Lung Ventilation: a Randomized, Pilot, Trial
The goal of this clinical trial is to compare in patients undergoing thoracic procedures the lung inflammatory response in on one-lung ventilation and two-lung ventilation strategies The main question to answer is: Lung…
- Trial name
- NCT05982639
- Testing
- two lung ventilation, one lung ventilation
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Universidade do Extremo Sul Catarinense - Unidade Academica de Ciecias da Saude
Lung Neoplasms
The Impacts of Pulmonary Rehabilitation Therapy on Patients After Thoracic Surgery
The advantages of thoracoscopic surgery include smaller wounds, fewer postoperative complications, and shortened hospital stay. However,complications such as pain, pulmonary function insufficiency, pneumonia,postoperative…
- Trial name
- VATSMIPMEP (NCT02757092)
- Testing
- Home-based Pulmonary Rehabilitation
- Where
- 2 sites in Taiwan
- Volunteers
- 36 people
- Sponsor
- Chang Gung Memorial Hospital
Goal-directed Fluid Therapy
Goal Directed Fluid Therapy Guided Fluid Management in Pneumoresection
Perioperative fluid management is a key component of anesthetic management during thoracic surgery. On one hand, fluid restriction could compromise perfusion of vital organs and surgical anastomosis.
- Trial name
- NCT03237351
- Testing
- Fluid therapy
- Where
- China
- Volunteers
- 60 people
- Sponsor
- ZhiHeng Liu
Pulmonary Air Leak
Experiences With New Digital Surgical Drainage System in Thoracic Surgery
The purpose of this study is to evaluate the Thoraguard Surgical Drainage System in a real-world clinical environment. It is believed that this system will offer functional and clinical benefits over the current standard of care…
- Trial name
- NCT04068545
- Testing
- Device: Thoraguard Surgical Drainage System
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Centese, Inc.
Thoracic
Surgical Outcome Studies in Thoracic Wall Reconstruction With Codubix® Ribs
The aim of this observational study is to analyze the short- and long-term outcome after surgical implantation of the Codubix® Ribs prosthesis in a descriptive and non-statistical way.
- Trial name
- NCT06448728
- Where
- Switzerland
- Volunteers
- 9 people
- Sponsor
- University Hospital, Basel, Switzerland
Atrial Fibrillation
Treatment of Atrial Fibrillation by Minimal Invasive Surgery
The purpose of this study is to determine the feasability of a new epicardial and minimal invasive ablation technique of the left atrium isolating the pulmonary veins for prevention of atrial fibrillation recurrences in patients…
- Trial name
- ABOLISH-AF (NCT00448656)
- Testing
- ablation of pulmonary veins by video assisted thoracic surgery
- Where
- Netherlands
- Volunteers
- 15 people
- Sponsor
- University Medical Center Groningen
Pulmonary Air Leak
Effects of Local Protocols on Duration of Chest Tube Therapy Following Thoracic Surgery
The effect of local chest-tube management protocols on the duration of chest-tube therapy following thoracic surgery was analyzed in four German specialized Thoracic Surgery Units.
- Trial name
- NCT01467622
- Testing
- Chest tube removal
- Where
- 4 sites in Germany
- Volunteers
- 80 people
- Sponsor
- Schillerhoehe Hospital
Myocardial Infarction, Percutaneous Coronary Intervention
Text Message Intervention to Improve Cardiac Rehab Participation
Cardiac rehabilitation (CR) is strongly recommended for patients with coronary heart disease. However, patient enrollment and completion of cardiac rehabilitation is low.
- Conditions
- Myocardial Infarction, Percutaneous Coronary Intervention, Coronary Artery Bypass Surgery, Heart Valve Repair or Replacement
- Trial name
- NCT03346278
- Testing
- Text Messaging Intervention
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- University of Washington
Lung Cancer
Ketamine In Thoracic Surgery (KITS) Trial
The primary aim of the study is to demonstrate a reduction in circulating interleukin 6 levels at 4 and 24 hours after completion of lobectomy (either VATS or open).
- Trial name
- KITS (NCT00504725)
- Testing
- Ketamine, 0.9% saline
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Duke University
Colorectal Neoplasms, Lung Neoplasms
Preoperative High Intensity Interval Training: The PHIIT Trial
Colorectal and thoracic surgical patients are susceptible to poor postoperative outcome including complications, mortality and increased length of stay.
- Trial name
- PHIIT (NCT02674815)
- Testing
- High Intensity Interval Training Exercise programme
- Where
- Ireland
- Volunteers
- 20 people
- Sponsor
- University of Dublin, Trinity College
Thoracic
Chest-Up: Obtaining Safe Positioning for Thoracic Surgery
Thoracotomy surgeries, both open and video assisted, are often carried out in the lateral decubitus position to optimize surgical access to the operative side.
- Trial name
- NCT04462497
- Testing
- Prototype device
- Where
- Singapore
- Volunteers
- 50 people
- Sponsor
- National University Hospital, Singapore
Lung Cancer
Prolonged Air Leak (PAL) Autologous Blood Patch Intervention Trial
A postoperative autologous blood patch (ABP) intervention trial for patients who underwent lung resection for cancer to examine its effectiveness in preventing a prolonged air leak.
- Trial name
- NCT04954625
- Testing
- Autologous Blood Patch, Standard of Care (per Physician)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Rush University Medical Center
Early-Stage Non-Small Cell Lung Cancer
A Study to Assess The Safety and Tolerability of Pumitamig-Based Therapy Administered Before Surgery in Participants With Early-Stage Non-Small Cell Lung Cancer (ROSETTA Lung-220)
The purpose of this study is to assess the safety, tolerability, and surgical feasibility of preoperative Pumitamig-based therapy and other molecules in resectable, Early-Stage Non-Small Cell Lung Cancer
- Trial name
- NCT07871214
- Testing
- Pumitamig, Carboplatin, Cisplatin
- Where
- 50 sites in United States, Australia and 12 more
- Volunteers
- 80 people
- Sponsor
- Bristol-Myers Squibb
Thoracic Surgery
ACBT With Incentive Spirometry Versus High-Frequency Chest Wall Oscillation After Thoracic Surgery
This randomized clinical trial aims to compare the effectiveness of Active Cycle of Breathing Techniques combined with Incentive Spirometry (ACBT + IS) versus High-Frequency Chest Wall Oscillation (HFCWO) in patients undergoing…
- Trial name
- NCT07619716
- Testing
- Active Cycle of Breathing Techniques with Incentive Spirometry, High-Frequency Chest Wall Oscillation
- Where
- Pakistan
- Volunteers
- 42 people
- Sponsor
- Riphah International University
Lung Neoplasms
Systemic, Intrapulmonary and Pleural Inflammatory Reaction in Patients Undergoing Thoracic Surgery
Inflammatory reaction in different compartments of the body may have a negative effect on outcome. This study assesses the inflammatory reaction systemically, intrapulmonary and intrapleural by measuring different cytokines.
- Trial name
- NCT00558350
- Where
- Switzerland
- Volunteers
- 15 people
- Sponsor
- University Hospital, Basel, Switzerland
Pneumonia, Postoperative, Anesthesia
Reducing Pneumonia with LMA in Lung Wedge Resection
This retrospective cohort study aims to evaluate whether spontaneous breathing laryngeal mask anesthesia (LMA-SBA) reduces the incidence of postoperative pneumonia compared to single-lung isolation mechanical ventilation in…
- Conditions
- Pneumonia, Postoperative, Anesthesia, Thoracic Surgery, Thoracoscopic Wedge Resection
- Trial name
- NCT06873958
- Where
- China
- Volunteers
- 700 people
- Sponsor
- Hai Feng
Opioid Free Anesthesia, Thoracic Surgery
Opioid-free Anesthesia and Thoracoscopy Surgery
Evaluation of a service OFA (Opioid-free Anesthesia) protocol on post-operative pain of patients operated on by video-thoracoscopic carcinologic surgery by counting them to a group of patients receiving standard general…
- Trial name
- OFAT (NCT05308355)
- Where
- France
- Volunteers
- 90 people
- Sponsor
- Nantes University Hospital
Postoperative Pulmonary Complications (PPCs)
Prediction of Postoperative Pulmonary Complications in Thoracic Surgery
Lung cancer is a common disease, and its treatment is lobectomy or pulmonary segmentectomy. In France, approximately 8,000 patients undergo this procedure each year, but it remains associated with significant Postoperative…
- Trial name
- PREDICT-PPC (NCT07359885)
- Testing
- Evaluation of prognostic performance of a defined score using a machine learning method (STABL: Stability Selection) integrating immune data (cytometric and proteomic)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Rouen
Local Anesthetic Systemic Toxicity, Pain
Ropivacaine Pharmacokinetics in ESP Blocks
This is a pharmacokinetic study to determine risk of local anesthetic systemic toxicity of ropivacaine when used in erector spinae plane blocks for thoracic surgery.
- Conditions
- Local Anesthetic Systemic Toxicity, Pain, Quality of Recovery
- Trial name
- NCT04807504
- Testing
- Ropivacaine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Thomas Jefferson University
Pain, Postoperative, Thoracic Surgery, Video-Assisted
Efficacy of Bi-level ESPB Application in Patients Undergoing VATS
Video-assisted thoracic surgery (VATS) has become a common procedure in thoracic surgery. Severe postoperative pain may be encountered in patients undergoing VATS.
- Conditions
- Pain, Postoperative, Thoracic Surgery, Video-Assisted, Erector Spinae Plane Block, Multimodal Analgesia
- Trial name
- NCT05427955
- Testing
- One-level Erector Spinae Plane Block, Bi-level Erector Spinae Plane Block
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ankara City Hospital Bilkent