Clinical trials: Thoracic Surgical Procedures
Regional Anesthesia, Diaphragm Issues
Ultrasound Assessment of Diaphragmatic Dysfunction in Regional Anesthesia
Awake thoracic surgery is a feasible and safe alternative to general anesthesia for pulmonary biopsy in interstitial lung disease patients, but there is still no evidence as to its superiority in terms of outcome.
- Conditions
- Regional Anesthesia, Diaphragm Issues, Thoracic Surgery, Ultrasounds
- Trial name
- NCT04700943
- Testing
- Regional awake anesthesia
- Where
- Italy
- Volunteers
- 41 people
- Sponsor
- University of Turin, Italy
Intubation; Difficult, Intubation Complication
McGrath Series 5 Videolaryngoscope for Double-lumen Tube Intubation
1. Double-lumen tube intubation is difficult, compared with single lume tube. 2. McGrath Series 5 videolaryngoscope hase been used in difficult airway management, both in anesthetized and awake patients. 3.
- Trial name
- NCT01984970
- Testing
- videolaryngoscope
- Where
- China
- Volunteers
- 43 people
- Sponsor
- Huazhong University of Science and Technology
Pain, Postoperative, Multimodal Analgesia
Comparison of the Rhomboid Intercostal Block and Serratus Posterior Superior Intercostal Plane Block
Video-assisted thoracic surgery (VATS) is widely performed for the management of various thoracic pathologies and is generally associated with reduced surgical trauma compared with open thoracotomy.
- Conditions
- Pain, Postoperative, Multimodal Analgesia, Rhomboid Intercostal Block, Serratus Posterior Superior Intercostal Plane Block
- Trial name
- NCT07650877
- Testing
- Rhomboid Intercostal Block, Serratus Posterior Superior Intercostal Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Ankara City Hospital Bilkent
Video-assisted Thoracic Surgery, Lung Cancer
Mixed Reality Technique Combined With 3D Printing Navigational Template for Localizing Pulmonary Nodules
This study evaluates the viability and accuracy of preoperative mixed reality technique combined with three-dimensional printing navigational template guided localizing pulmonary small nodules.
- Conditions
- Video-assisted Thoracic Surgery, Lung Cancer, Pulmonary Nodule, Solitary, Pulmonary Nodule, Multiple
- Trial name
- MR&3D Local (NCT04552054)
- Testing
- Mixed Reality+ 3D printing guided localization, Computerized Tomography guided localization
- Where
- China
- Volunteers
- 136 people
- Sponsor
- Wen-zhao ZHONG
Thoracic Surgery, Tidal Volume
Tidal Volume Adjustment According to Forced Vital Capacity Versus Predicted Body Weight in Thoracic Surgery Patients
The goal of this observational study is to learn about the intraoperative and postoperative pulmonary effects of tidal volume adjustment according to force vital capacity in thoracic surgery patients.
- Conditions
- Thoracic Surgery, Tidal Volume, Forced Vital Capacity, Predicted Body Weight
- Trial name
- NCT06608602
- Testing
- tidal volume adjustment during surgery
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Cukurova University
Thoracic Surgery, Video-Assisted
Two-Lumen Catheterization For Lung Wedge Resection
This study evaluates the viability and safety of two-lumen catheterization versus chest tube placement in patients with lung wedge resection.
- Trial name
- NCT03230019
- Testing
- chest tube, two-lumen catheterization, two-lumen catheter
- Where
- China
- Volunteers
- 96 people
- Sponsor
- Wen-zhao ZHONG
Delirium, Thoracic Surgery
Cerebral Oxygen Desaturation and Post-Operative Delirium in Thoracic Surgical Patients
This study will assess the incidence and risk factors for post-operative delirium in patients undergoing thoracotomy. Specifically, the study will assess if there is any relationship between an intra-operative decrease in brain…
- Trial name
- NCT03165539
- Testing
- Cerebral oxygen saturation monitoring
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- University of Manitoba
Perioperative/Postoperative Complications
Preoperative Laboratory Parameters and Scorings Systems on Postoperative Pulmonary Complications in Thoracic Surgery
Postoperative pulmonary complications (PPC) emerge as a major risk that determines the morbidity and mortality of patients after surgery. PPCs affect the length of hospital stay and increase health costs.
- Trial name
- NCT04995939
- Testing
- Laboratory parameters and Scoring systems
- Where
- Turkey (Türkiye)
- Volunteers
- 130 people
- Sponsor
- Atatürk Chest Diseases and Chest Surgery Training and Research Hospital
Surgery, One-lung Ventilation
Esophageal Pressure Measurements During One-lung Ventilation
The investigators will assess the feasibility and validity of esophageal pressure measurements during one-lung ventilation in the lateral position for surgery by comparing to lung collapse estimated from electrical impedance…
- Trial name
- NCT04725318
- Testing
- One-lung ventilation
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Beth Israel Deaconess Medical Center
Paresthesia, Dysesthesia
Sensory Mapping Following Video-assisted Thoracic Surgery
This is a prospective observational cohort study on changes in sensory mapping.
- Conditions
- Paresthesia, Dysesthesia, Pain
- Trial name
- NCT01375283
- Where
- Denmark
- Volunteers
- 48 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Acupuncture, Pain Control
Acupuncture in Postoperative Pain Control for Minimal Invasive Thoracoscopic Surgery Patients
Minimal invasive thoracoscopic surgery has been used widely for common thoracic diseases in recent years. Patients who received thoracoscopic surgery recovered much quickly and returned to their daily life sooner because of small…
- Conditions
- Acupuncture, Pain Control, Randomized Controlled Trial, Thoracic Surgery
- Trial name
- NCT02959346
- Testing
- Acupuncture
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- China Medical University Hospital
Postoperative Pain, Thoracic Cancer
Ultrasound-guided Block for Thoracic Surgery Pain
The investigators aimed to assess Ultrasounde- guided serratus anterior plane block can be effective in acute postoperative pain following thoracic surgery.
- Trial name
- NCT03240562
- Testing
- serratus anterior plane block, patient controlled analgesia
- Where
- South Korea
- Volunteers
- 89 people
- Sponsor
- Samsung Medical Center
VATS, Kinesiophobia
Comparison of Early Postoperative Functional Capacity and Kinesiophobia in Patients Undergoing Thoracic Surgery Via Thoracotomy or VATS
This observational cross-sectional study aims to compare early postoperative functional capacity and kinesiophobia in patients undergoing thoracic surgery via thoracotomy or video-assisted thoracic surgery (VATS).
- Conditions
- VATS, Kinesiophobia, Thoracotomy, Thoracic Surgery
- Trial name
- NCT07647822
- Where
- Turkey (Türkiye)
- Volunteers
- 18 people
- Sponsor
- Hacettepe University
Hypervolemia, Hypovolemia
Effects of Different Fluid Transfusion Regimens On Glycocalyx In Patients Undergoing Thoracic Surgery.
Introduction: Endothelial Glycocalyx (EG) composing of proteoglycans heparan sulfate (HS), syndecan, and plasma proteins forms a physiologically active surface layer on the vascular endothelium, regulates oncotic pressure.
- Trial name
- NCT07192523
- Testing
- Restrictive fluid therapy, Liberal fluid therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 41 people
- Sponsor
- Kocaeli Derince Education and Research Hospital
Thoracic Surgery, Anesthesia
Cerebral Oximetry-Guided Low FiO2 Strategies in Thoracic Surgery.
Brief Summary (Kısa Özet)The purpose of this study is to evaluate the safety and efficacy of a cerebral oximetry-guided low fraction of inspired oxygen (FiO_2) ventilation strategy compared to a standard high FiO_2 strategy in…
- Trial name
- NCT07659483
- Testing
- Standard High $FiO_2$ Strategy, Guided Low $FiO_2$ Strategy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Dicle University
Infective Endocarditis, Infection Related to Ventricular Assist Device
Retrospective Analysis of Nephrotoxicity During Daptomycin Versus Vancomycin Treatments in High Risk Patients
Acute kidney injury (AKI) is a frequent complication that occurs in 15 to 25% of patients after vascular surgery, and up to 40% of patients after cardiac surgery.
- Conditions
- Infective Endocarditis, Infection Related to Ventricular Assist Device, Infection Related to Vascular Prothesis, Surgical Site Infection
- Trial name
- DVN (NCT03961503)
- Testing
- Daptomycin (DAP) treatment, Vancomycin (VAN) treatment
- Where
- France
- Volunteers
- 72 people
- Sponsor
- University Hospital, Montpellier
Thoracic Surgery
Comparison of Bupivacaine Liposomal vs Bupivacaine Combined With Dexamethasone for Postoperative Pain in VATS
The purpose of this study, is to investigate the effectiveness of ultrasound-guided rhombic intercostal nerve block for postoperative pain control in thoracoscopic pulmonary resection with bupivacaine liposomes versus bupivacaine…
- Trial name
- NCT06392191
- Testing
- Rhombic intercostal nerve block(Received liposomal bupivacaine 93 mg and bupivacaine 25 mg diluted to 20 ml), Rhombic intercostal nerve block(Receive standard bupivacaine 105 mg diluted to 20 ml with dexamethasone 5 mg.)
- Where
- China
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Affiliated Hospital of Jiaxing University
Postoperative Pain, Acute, Postoperative Pain, Chronic
Application of Non-invasive Neurophysiological Methods in Predicting and Evaluating Postoperative Pain in Adult Patients Undergoing Major Thoracic Surgery
The primary aim of this study is to explore the relationship between alpha electroencephalographic oscillations, particularly Peak Alpha Frequency (PAF), pupillometry, intraoperative Nociception Level (NOL) and postoperative pain…
- Conditions
- Postoperative Pain, Acute, Postoperative Pain, Chronic, Postoperative Pain After Thoracic Surgery
- Trial name
- NCT06731010
- Where
- 2 sites in Greece
- Volunteers
- 20 people
- Sponsor
- National and Kapodistrian University of Athens
Lung, Lung Adenocarcinoma
Reinforced and Non-Reinforced Staple Lines in Fissureless Lobectomy
Prolonged Air Leak (PAL) is a common and serious problem after lung surgery. It can lead to worse patient outcomes, longer hospital stays, and higher costs.
- Conditions
- Lung, Lung Adenocarcinoma, Lung Adenosquamous Carcinoma, Lung Cancer, Non-Small Cell
- Trial name
- NCT06602661
- Testing
- Fissureless Lobectomy with Reinforced Staple Lines, Fissureless Lobectomy with Non-Reinforced Staple Lines
- Where
- Canada
- Volunteers
- 65 people
- Sponsor
- Surrey Thoracic Surgery Group
Thoracic Diseases, Surgery
Geriatric Thoracic Surgery Ambulation Challenge
This study is examining collecting data on steps walked (ambulation) per day by thoracic surgery patients over the age of 65 years-old before surgery. The name(s) of the study device involved in this study is: Fitbit inspire
- Conditions
- Thoracic Diseases, Surgery, Therapy, Exercise
- Trial name
- NCT04630496
- Testing
- Fitbit
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Dana-Farber Cancer Institute