Clinical trials: Thoracic Trauma
Thoracic Surgery, Cardiopulmonary Bypass
Cerebral Autoregulation Monitoring During Cardiac Surgery
Neurological complications from cardiac surgery are an important source of operative mortality, prolonged hospitalization, health care expenditure, and impaired quality of life.
- Trial name
- NCT00981474
- Testing
- blood pressure maintenance based on cerebral blood flow autoregulation measurement, Control group
- Where
- United States
- Volunteers
- 460 people
- Sponsor
- Northwestern University
Spinal Cord Injury Thoracic
Electromyography-Triggered Electrical Stimulation on Trunk Balance and Muscle Thickness in SCI Patients
The aim of this study was to investigate the effect of electromyography (EMG) triggered electrical stimulation (ES) applied to multifidus and erector spinae muscles on trunk balance in patients with complete thoracic spinal cord…
- Trial name
- NCT06527417
- Testing
- Neuro Trac Myo Plus Pro, Trunk eccentric exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people
- Sponsor
- Ankara City Hospital Bilkent
Patients withInfections Caused by S.Aureus Like Skin Infections , Chest Infections , Surgical Site Infections , and Urinary Tract Infections
Detection of Efflux Pump Genes Mediating Ciprofloxacin Resistance in Staphylococcus Aureus Isolates in Sohag University Hospitals
Among multidrug-resistant bacteria, Methicillin-resistant Staphylococcus aureus (MRSA) isolates were recognized to be an important mortality factor in hospital infections and a major concern in health-care and community settings…
- Trial name
- NCT05828550
- Testing
- antibiotic sensitivity
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Sohag University
Oncology, Breast Cancer
The MOMENTUM Study: The Multiple Outcome Evaluation of Radiation Therapy Using the MR-Linac Study
The Multi-OutcoMe EvaluatioN of radiation Therapy Using the Unity MR-Linac Study (MOMENTUM) is a multi-institutional, international registry facilitating evidenced based implementation of the Unity MR-Linac technology and further…
- Conditions
- Oncology, Breast Cancer, Prostate Cancer, Gynecologic Cancer
- Trial name
- MOMENTUM (NCT04075305)
- Testing
- Radiation therapy
- Where
- 18 sites in United States, Australia and 7 more
- Volunteers
- 8,000 people
- Sponsor
- UMC Utrecht
Acute Hypoxemic Respiratory Failure, Diaphragm Injury
Feasibility of Transvenous Phrenic Nerve Stimulation for Diaphragm Protection in Acute Respiratory Failure
This is a single-center proof-of-concept clinical trial designed to establish the feasibility of transvenous phrenic-nerve stimulation (PNS) to maintain diaphragm activation over the first 24 hours and for up to seven days of…
- Conditions
- Acute Hypoxemic Respiratory Failure, Diaphragm Injury, Lung Injury
- Trial name
- STIMULUS (NCT05465083)
- Testing
- Lungpacer AeroPace Protect System
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University Health Network, Toronto
Small Cell Lung Cancer, Limited Stage, Stage III Non-small Cell Lung Cancer
Image-Guided Functional Lung Avoidance Thoracic Radiotherapy for Lung Cancer: A Single-Blind Randomized Trial
Thoracic radiotherapy (TRT) is a standard curative treatment for locally advanced, unresectable non-small cell lung cancer (NSCLC) and limited stage small cell lung cancer (SCLC).
- Trial name
- NCT03077854
- Testing
- Functional Lung Avoidance Thoracic Radiotherapy, Standard Thoracic Radiotherapy
- Where
- Taiwan
- Volunteers
- 64 people
- Sponsor
- National Taiwan University Hospital
Hypotension, Hip Fractures
Heart and Renal Failure in Hip Fracture Surgery
Patients with acute hip fractures are old and vulnerable. With a majoriry classified as being ASA 3 or more. Frequently they receive spinal anesthesia perioperatively inducing hypotension.
- Conditions
- Hypotension, Hip Fractures, Renal Insufficiency, Heart Injuries
- Trial name
- NCT03532919
- Testing
- Serum Tropinin
- Where
- Sweden
- Volunteers
- 105 people
- Sponsor
- Sahlgrenska University Hospital
Lung Injury, Lung Inflammation
The Effects of Different Ventilation Modes on Patients With Pulmonary Lobe Resection
The objective of this study was to discuss the effects of different ventilation modes on patients with plasma inflammatory factor and respiratory function in patients with pulmonary removal.
- Trial name
- NCT06514729
- Testing
- Adopting different ventilation modes during the operation
- Where
- China
- Volunteers
- 102 people
- Sponsor
- Mao Enting
Single Level Stable Thoracolumbar Fracture Type AO A3, Multiple Level Stable Thoracolumbar Fracture Type AO A3
Spine FA3 - a Prospective, International, Multicenter Cohort Study on Treatment of of AO A3 Thoracolumbar Fractures
Thoracolumbar fractures are the most common spinal fractures with an average annual incidence between 18 and 30 per 100'000 inhabitants. The majority of these fractures are AO type A3 ("burst fractures").
- Trial name
- FA3 (NCT01751633)
- Testing
- Surgical, Conservative treatment
- Where
- 8 sites in Brazil, Chile and 4 more
- Volunteers
- 38 people
- Sponsor
- AO Clinical Investigation and Publishing Documentation
Lung Injury
Stem Cell Treatment for Lung Injury Caused by Major Infectious Diseases
The goal of this study is to conduct a prospective, double-blind, randomized placebo-controlled clinical trial to investigate the safety and efficacy of mesenchymal stem cells treatment for Lung injury caused by major infectious…
- Trial name
- NCT06416709
- Testing
- mesenchymal stem cells, saline
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Cell Energy Life Sciences Group Co. LTD
Thorax; Fracture, Pain; Thorax, Thoracic, Spine, With Radicular and Visceral Pain
Effect of Coolant Spray on Traumatic Rib Pain of Geriatric Patients
This study aims to evaluate the effectiveness of cryotherapy in the early period pain treatment of elderly patients with rib fractures due to blunt thoracic trauma.In this prospective randomized controlled study, geriatric…
- Trial name
- NCT04937933
- Testing
- Coolant spray (Cryos ®Spray, Phyto Performance, Italy), Saline solution
- Where
- Turkey (Türkiye)
- Volunteers
- 101 people
- Sponsor
- Ataturk University
Brain Injuries
Influence of Respiratory Mechanics on Brain-specific Monitoring in Brain-injured Patients
Increase in intracranial pressure (ICP) could be associated with increase in positive end-expiratory pressure (PEEP) level. Data are however disparate and interactions between ventilation with high PEEP and intracranial…
- Trial name
- ABIVENT (NCT04013698)
- Testing
- PEEP level 5 cmH2O, PEEP level 15 cmH2O
- Where
- Switzerland
- Sponsor
- Piquilloud Imboden Lise
Thoracic Spine Fracture, Concomitant Sternal Fracture
The Unstable Thoracic Cage Injury
Analysis of patient data and computed tomography scan of polytraumatized patients thoracic spine fractures A concomitant sternal fracture was identified an indicator for an unstable thoracic spine fracture
- Trial name
- NCT02514993
- Volunteers
- 130 people
- Sponsor
- BG Unfallklinik Murnau
Blunt Injury of Thorax
Nebulized Morphine in Chest Trauma Patients: A Prospective Study
This is a prospective study carried out from 2018 to 2020 including patients aged ≥ 18 years, admitted for isolated chest trauma. Each patient received a nebulization of 10 mg morphine.
- Trial name
- NCT03580187
- Testing
- Morphine (+)
- Where
- Tunisia
- Volunteers
- 75 people
- Sponsor
- University Hospital, Mahdia
Rib Fracture, Flail Chest
Rib Fixation for Clinically Severe Rib Fractures From Trauma
This is a multicenter randomized study investigating the differences in clinical outcomes of patients between two standard of care pathways for rib trauma: patients who receive rib fixation versus patients who receive modern…
- Trial name
- SOFRIB (NCT02595593)
- Testing
- Rib Fixation System
- Where
- 10 sites in United States
- Volunteers
- 236 people
- Sponsor
- Darwin Ang
Dislocation, Infection
Fixation of Thoracic Epidurals Influencing Catheter-related Infections and Dislocation
Major interest in our investigation is to find out whether distinct fixation techniques influence catheter dislocation and/ or incidence of local inflammation.
- Conditions
- Dislocation, Infection, Line Colonisation, Line Insertion Site
- Trial name
- TDPAFD (NCT01402778)
- Where
- Germany
- Volunteers
- 140 people
- Sponsor
- Heinrich-Heine University, Duesseldorf
Rib Fracture
The Analgesic Effect of Retro-laminar Block Versus Paravertebral Block in Patients With Multiple Fracture Ribs
Rib fractures are a common injury, occurring in up to 10% of all trauma patients. Multiple rib fractures can be particularly painful and debilitating, making it difficult for patients to breathe and cough.
- Trial name
- NCT06757803
- Testing
- rertrolaminar block, paravertebral block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Immune Checkpoint Inhibitors, Liver Injury
A Clinical Study on the Analysis of Risk Factors for the Occurrence of PD-1/PD-L1 Inhibitor-associated Liver Injury in Lung Cancer Patients
The goal of this observational study is to investigate the risk factors of PD-1/PD-L1 inhibitor-associated liver injury, to construct a prediction model for the occurrence of liver injury.
- Trial name
- NCT06402981
- Testing
- High risk prediction model for liver injury
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Zhejiang University
Impingement Shoulder
Thoracic Manipulation Versus Myofascial Release in Patients With Shoulder Impingement Syndrome
aims: • To investigate the effect of adding thoracic manipulation vs myofascial release to scapular stabilization exercise on pain intensity.
- Trial name
- NCT05104671
- Testing
- scapular stabilization exercises., Thoracic manipulation., Myofascial release.
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- manar sameh el taher
Spinal Cord Injury, Tetraplegia
Effect of Air-stacking on Peak Cough Flow in Patients With Acute Cervical or High Thoracic Spinal Cord Injury
Respiratory complications continue to be one of the leading causes of morbidity and mortality in people with spinal cord injury, especially among cervical and higher thoracic injuries.
- Trial name
- NCT01046175
- Testing
- Air-stacking with a manual resuscitator, Air-stacking with ventilator
- Where
- Norway
- Volunteers
- 10 people
- Sponsor
- Ullevaal University Hospital