Clinical trials: Thoracic Trauma
Work of Breathing, Lung Transplantation
Electrical Activity of the Diaphragm and Respiratory Mechanics During NAVA
Protective ventilatory strategy should be applied to reduce ventilator-induced lung injury (VILI) after Lung Transplantation (LTx) or in case of acute respiratory failure requiring invasive mechanical ventilation.
- Conditions
- Work of Breathing, Lung Transplantation, Neurally Adjusted Ventilatory Assist, Ventilator-Induced Lung Injury
- Trial name
- NAVAMECH (NCT05689476)
- Testing
- NAVA GROUP
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Padova
Covid-19
CLBS119 for Repair of COVID-19 Induced Pulmonary Damage
This clinical trial will explore the safety and potential efficacy of CLBS119 for the repair of COVID-19 induced pulmonary damage in adults.
- Trial name
- NCT04522817
- Testing
- CLBS119
- Where
- United States
- Sponsor
- Lisata Therapeutics, Inc.
Pulmonary Fibrosis, Unspecified
68Ga-NOTA-PRGD2 PET/CT in Patients With Lung Injury and Pulmonary Fibrosis
This is an open-label positron emission tomography/computed tomography (PET/CT) study to investigate the diagnostic performance and evaluation efficacy of 68Ga-NOTA-PRGD2 in lung injury (LI) and pulmonary fibrosis (PF) patients.
- Trial name
- NCT02511197
- Testing
- 68Ga-NOTA-PRGD2, PET/CT
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Peking Union Medical College Hospital
Shortness of Breath, Chest Pain
Checklists Resuscitation Emergency Department
The study will systematically evaluate how an emergency manual-a collection of checklists and fact sheets-affects the performance of resuscitation teams during the management of priority one patients in an emergency department.
- Conditions
- Shortness of Breath, Chest Pain, Abdominal Pain, Altered Mental Status
- Trial name
- NCT05649891
- Testing
- Emergency Manual
- Volunteers
- 2,000 people
- Sponsor
- Region Skane
Flail Chest, Rib Fractures
Mortality Causes in Rib Surgery Patients
This study retrospectively investigates the causes of mortality and morbidity in patients undergoing rib fracture surgery due to blunt trauma.
- Conditions
- Flail Chest, Rib Fractures, Thoracic Injuries, Pulmonary Contusion
- Trial name
- NCT06755723
- Testing
- Rib fractures manangement
- Volunteers
- 112 people
- Sponsor
- Caner İşevi, MD
Chest Trauma
Predictive Value of Chest Trauma Score , Revised Trauma Score , and Glasgow Coma Scale in Patients Presenting With Chest Trauma at Assiut University Emergency Unit.
Thoracic trauma is a critical clinical entity and a major global public health burden, representing the second most frequently occurring unintentional traumatic injury and the third most common cause of death-following head and…
- Trial name
- NCT07812038
- Volunteers
- 100 people
- Sponsor
- Assiut University
Aortic Dissection
Zenith® Dissection Clinical Trial
The Zenith® Dissection Clinical Trial is a clinical trial approved by US FDA to study the safety and effectiveness of the Zenith® Dissection Endovascular System in the treatment of acute, complicate Type B aortic dissection.
- Trial name
- NCT01568320
- Testing
- Endovascular Treatment (Zenith)
- Where
- 24 sites in United States, Japan
- Volunteers
- 73 people
- Sponsor
- Cook Research Incorporated
Wounds and Injuries, Wound Infection
Effects of Early Postoperative Showering After Coronary Artery Bypass Grafting Using Bilateral Internal Thoracic Artery
The study to evaluate effects of early postoperative showering after coronary artery bypass grafting using bilateral internal thoracic artery
- Trial name
- NCT06237283
- Testing
- Early shower
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Sejong General Hospital
Post Operative Pain, Pain, Acute
Post-thoracotomy Pain Management With Active External Warming and Ice Application
The aim of study is to investigate the effects of active external warming of patient concurrently with application of ice to incision site on thoracotomy pain and analgesic consumption.
- Conditions
- Post Operative Pain, Pain, Acute, Thoracic Injury
- Trial name
- NCT05299788
- Testing
- Active external warming, Ice application
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Akdeniz University
Thoracic Injury
Delphi Study to Identify Crucial Steps and Errors in the Placement of Chest Tubes
The goal of this Delphi study is to identify the crucial steps and the errors in Chest Tube Insertion (CTI). These steps and errors will be used for the development of a new assessment tool based on international consensus.
- Trial name
- NCT05623631
- Testing
- Survey
- Where
- Belgium
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University Ghent
Shoulder Impingement Syndrome
Short-term Effects of Thoracic Manipulation in Shoulder Impingement
The hypothesis of this study is that thoracic spine manipulation would reduce pain in subjects with SIS and cause changes in scapular kinematics and muscle activity in subjects with impingement symptoms and in asymptomatic…
- Trial name
- NCT02083796
- Testing
- Shoulder impingement_TSM, Asymptomatic_TSM
- Where
- Brazil
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Sao Carlos
Small Airways Diseases, Vaping
The Canadian Lung Outcomes in Users of Vaping Devices Study
Vaping is increasingly popular with both adolescent and adult Canadians, but the long-term health impacts remain unknown. We believe that the tools we currently have to detect lung disease in people who vape may be insufficient…
- Conditions
- Small Airways Diseases, Vaping, Vaping Related Disorder, Vaping Teens
- Trial name
- CLOUD (NCT06819969)
- Where
- 8 sites in Canada
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Sepsis, Lung Injury
Inhalational Versus Intravenous Anesthesia on Postoperative Lung Injury in Septic Patients Undergoing Surgery
This randomized controlled trial will compare the effects of intraoperative inhalational anesthesia versus intravenous anesthesia on postoperative lung injury in septic patients undergoing surgery.
- Trial name
- NCT07601256
- Testing
- Inhalation Anesthesia, intravenous anesthesia
- Where
- China
- Volunteers
- 480 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Lung Cancer, Pneumonitis
Incentive Spirometry to Improve Outcomes in Lung Cancer Patients Undergoing Concurrent Chemotherapy and Radiation Therapy
The goal of this clinical trial is to learn if using an incentive spirometer can reduce lung problems in people with advanced lung cancer who are receiving chemotherapy and radiation therapy.
- Conditions
- Lung Cancer, Pneumonitis, Radiation-Induced Lung Injury, Immunotherapy-Induced Pneumonitis
- Trial name
- INSPIRE-CRT (NCT06688422)
- Testing
- incentive spirometry
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- The Cooper Health System
Thorax; Fracture, Pain; Thorax, Thoracic, Spine, With Radicular and Visceral Pain
Effect of Coolant Spray on Traumatic Rib Pain of Geriatric Patients
This study aims to evaluate the effectiveness of cryotherapy in the early period pain treatment of elderly patients with rib fractures due to blunt thoracic trauma.In this prospective randomized controlled study, geriatric…
- Trial name
- NCT04937933
- Testing
- Coolant spray (Cryos ®Spray, Phyto Performance, Italy), Saline solution
- Where
- Turkey (Türkiye)
- Volunteers
- 101 people
- Sponsor
- Ataturk University
Kidney Injury Following Open-Chest Cardiac Surgery
A Phase 2b Dose Finding Study of RMC-035 in Participants Undergoing Open-chest Cardiac Surgery
The goal of this clinical trial is to identify the optimal dose of RMC-035 for protection of long-term renal function in adult patients undergoing cardiac surgery who are at high risk of kidney injury.
- Trial name
- POINTER (NCT06475274)
- Testing
- RMC-035
- Where
- 19 sites in Canada, Czechia and 2 more
- Volunteers
- 170 people
- Sponsor
- Guard Therapeutics AB
Fracture Rib, Acromioclavicular Joint Dislocation
Kinesiotaping in Trauma
Rationale: Patients with acute traumatic injury to the shoulder or chest wall in de Emergency Department (ED) usually have intense pain.
- Conditions
- Fracture Rib, Acromioclavicular Joint Dislocation, Fracture Clavicle, Fracture, Proximal Humeral
- Trial name
- KIT (NCT05976256)
- Testing
- Kinesio taping, standard treatment
- Where
- Netherlands
- Volunteers
- 387 people, healthy volunteers welcome
- Sponsor
- Onze Lieve Vrouwe Gasthuis
Analgesia
Serratus Anterior Plane Block , Paravertebral Block and Quality of Analgesia in Patients With Blunt Chest Trauma
Pain associated with rib movement cause inability to cough and breathe deeply that leads to reduction in the tidal volume and predisposes to significant atelectasis, sputum retention, pneumonia and a reduction in functional…
- Trial name
- NCT03890757
- Testing
- ultrasound guided paravertebral or serratus anterior block
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Samaa Rashwan
Immune Checkpoint Inhibitors, Liver Injury
A Clinical Study on the Analysis of Risk Factors for the Occurrence of PD-1/PD-L1 Inhibitor-associated Liver Injury in Lung Cancer Patients
The goal of this observational study is to investigate the risk factors of PD-1/PD-L1 inhibitor-associated liver injury, to construct a prediction model for the occurrence of liver injury.
- Trial name
- NCT06402981
- Testing
- High risk prediction model for liver injury
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Zhejiang University
Acute Respiratory Distress Syndrome (ARDS), Acute Lung Injury (ALI)
Trial of Steroids in Pediatric Acute Lung Injury/ARDS
Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are devastating disorders associated with lung inflammation, low oxygen levels and respiratory failure in children.
- Trial name
- SPALIT (NCT01274260)
- Testing
- methylprednisolone, Normal Saline (0.9%)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Tennessee