Clinical trials: Thoracic Trauma
Pulmonary Embolism, Deep Vein Thrombosis
Non-Interruptive Alerts for Improving Use of Clinical Decision Rules
This study is an extension of a planned quality improvement project that aims to promote standard of care by increasing the use of evidence-based clinical decision rules amongst emergency medicine providers in the University of…
- Conditions
- Pulmonary Embolism, Deep Vein Thrombosis, Minor Head Injury, Chest Pain
- Trial name
- NCT04702308
- Testing
- Clinical Decision Rule Alerts
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Utah
Breast Cancer, Radiation Dermatitis
Clinical Investigation on the Treatment of Radiation Induced Dermatitis With FR-101 Chest Dressing
Breast cancer is the top one incidence of cancer in women. Whole breast radiation therapy plays an indispensable role in the course of breast cancer treatment, and the radiation dermatitis is the major side effect affected…
- Trial name
- NCT06040983
- Testing
- FR-101 Chest Dressing
- Volunteers
- 30 people
- Sponsor
- China Medical University Hospital
Blunt Injury
Thoracic Endovascular Repair Versus Open Surgery for Blunt Injury
This study aims to increase understanding of the short-term and long-term outcome of blunt aortic injury (BAI) and to discern if there is an advantage resulting from the type of operative treatment used to manage it, either the…
- Trial name
- TEVAR (NCT01852773)
- Testing
- Open repair of thoracic aorta injury, TEVAR
- Where
- United States
- Sponsor
- Scripps Health
Shoulder Impingement
Cervical Unilateral Antero-posterior Mobilization and Thoracic Central Postro-anterior Mobilization in Treatment of Shoulder Impingement Syndrome
Shoulder impingement syndrome (SIS) is a complex, multi-factorial problem that is treated with a variety of different conservative options.
- Trial name
- NCT06349746
- Testing
- therapeutic exercises, mobilization exercise
- Where
- Egypt
- Volunteers
- 56 people
- Sponsor
- Egyptian Chinese University
Lung Contusion
AI in the Identification of Lung Contusions Through Chest Radiological Examination in Blunt Thoracic Trauma
The observational study focuses on comparing the interpretation of chest radiological examinations performed using a computer-based system with the standard interpretation conducted by a radiologist.
- Trial name
- NCT06777056
- Where
- Italy
- Volunteers
- 135 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Lung Protective Ventilation, Cardiopulmonary Bypass
Unilateral Ventilation on Cardiopulmonary Bypass During Cardiac Surgery
This study investigates if single lung ventilation on cardiopulmonary bypass can mitigate postoperative lung water accumulation determined by lung ultrasound in the ventilated lung as compared to the non-ventilated lung in…
- Conditions
- Lung Protective Ventilation, Cardiopulmonary Bypass, High-risk Cardiac Patients, Lung Ultrasound
- Trial name
- NCT07612709
- Testing
- Ventilated lung, Non-ventilated lung.
- Where
- Austria
- Volunteers
- 45 people
- Sponsor
- Medical University of Vienna
Radiation Pneumonitis
Prophylactic Inhaled Steroids to Reduce Radiation Pneumonitis Frequency and Severity in Lung Cancer Patients
This randomized clinical study aims to assess whether prophylactic treatment with inhaled steroids in patients with locally advanced or concomitantly treated non-small cell lung carcinoma who are candidates for combination…
- Trial name
- NCT03803787
- Testing
- Inhaled budesonide
- Where
- 2 sites in Mexico
- Volunteers
- 72 people
- Sponsor
- Instituto Nacional de Cancerologia de Mexico
Rheumatoid Arthritis, Ankylosing Spondylitis
PatientSpot Formerly Known as ArthritisPower
Patient Power is a patient research network and database (registry) to collect prospective information about demographics, self-reported diagnoses and medications, and willingness to participate in research from participants with…
- Conditions
- Rheumatoid Arthritis, Ankylosing Spondylitis, Fibromyalgia, Gout
- Trial name
- NCT03840928
- Where
- United States
- Volunteers
- 40,000 people, healthy volunteers welcome
- Sponsor
- Global Healthy Living Foundation
Metastatic Spinal Cord Compression, Radiation Toxicity
Esophagus-sparing Radiotherapy for Metastatic Spinal Cord Compression.
Metastatic spinal cord compression (MSCC) is a serious complication to metastatic cancer and when diagnosed life expectancy is short. Treatment is palliative radiotherapy (RT).
- Conditions
- Metastatic Spinal Cord Compression, Radiation Toxicity, Esophagitis, Patient Reported Outcome Measures
- Trial name
- ESO-SPARE (NCT05109819)
- Testing
- Esophagus sparring radiotherapy treatment
- Where
- 2 sites in Denmark
- Volunteers
- 200 people
- Sponsor
- Herlev Hospital
Analgesia, Thoracic Tumors
Real-time Ultrasound Guidance for Thoracic Epidural Blocks
Various modalities have been proposed for real-time confirmation of loss of resistance (LOR) for thoracic epidural blocks. With real-time ultrasound (US) guidance, the anesthesiologist attempts to visualize the sonographic…
- Conditions
- Analgesia, Thoracic Tumors, Abdomen Tumors, Rib Fractures
- Trial name
- NCT05165498
- Testing
- Real-time ultrasound guidance for thoracic epidural catheter placement.
- Where
- Chile
- Sponsor
- University of Chile
Myocardial Infarction
Acute Myocardial Infarction by Penetrating Cardiac Trauma
Patients with a cardiac stab wound could be complicated by a posttraumatic acute myocardial infarction (PAMI). Traditionally, the investigators can explain it by the occlusion of a coronary artery; but the PAMI isn´t constantly…
- Trial name
- NCT01182064
- Where
- Colombia
- Volunteers
- 51 people
- Sponsor
- Universidad de Antioquia
Rib Fractures, Nonunion of Fracture
Impact of Time Interval Between Trauma and Operation on Clinical Outcome in Patients With Delayed Rib Fixation (Nonunion)
The goal of this monocentric observational study is to evaluate the outcomes of patients who underwent a delayed surgical stabilization of rib fractures/surgical stabilization of rib fracture nonunion (SSRFN) based on the timing…
- Trial name
- NCT06788067
- Where
- Switzerland
- Volunteers
- 41 people
- Sponsor
- University Hospital, Basel, Switzerland
Unstable Angina Pectoris
Safety and Efficacy of Low Temperature Contrast in UAP Patients During PCI (LOTA-I)
Percutaneous coronary intervention (PCI) has become one of the main treatments for rapid recovery of revascularization in patients with coronary heart disease (CHD).
- Trial name
- LOTA-I (NCT03700567)
- Testing
- low temperature contrast
- Where
- 7 sites in China
- Volunteers
- 440 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Lung Injury, Bleb Lung
Polypropylene vs Polyglactin in Suturing of the Lung
Comparative study comparing polypropylene and Polyglactin in suturing of the lung
- Conditions
- Lung Injury, Bleb Lung, Lung Cancer
- Trial name
- NCT06115447
- Testing
- lung suturing with polyglactin, ung suturing with polypropylene
- Volunteers
- 100 people
- Sponsor
- Assiut University
Infection, Alcohol Abuse
Effect of Alcohol and Drugs of Abuse on Immune Function in Critically Ill Patients With Respiratory Failure
This study plans to learn more about people who are sick in the hospital with a lung infection, or respiratory failure. Respiratory failure, or severe lung failure, is a life-threatening disease.
- Conditions
- Infection, Alcohol Abuse, Drugs of Abuse, Lung Injury
- Trial name
- NCT02299921
- Testing
- Characterize alcohol and drug use
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of Colorado, Denver
Pain
Exparel for Pain Control During Care of Rib Fractures
This study is looking at a novel therapy of numbing medication injected directly around the fracture site. The purpose of this study is to determine if the study medication, EXPAREL®, is a viable alternative to current therapies…
- Trial name
- NCT02390440
- Testing
- EXPAREL
- Where
- United States
- Sponsor
- Michael Moncure, MD
Neonatal Resuscitation, Apnea Neonatal
Manual T-piece Versus Ventilator Positive Pressure Ventilation During Resuscitation of Extremely Premature Neonates
Many extremely premature infants require immediate help with breathing after birth. Positive pressure ventilation (PPV) using a device called a T-piece resuscitator is a common method.
- Trial name
- MVP (NCT06849596)
- Testing
- Ventilator derived positive pressure ventilation - V-PPV, T-piece resuscitator (TPR)
- Where
- 11 sites in United States, Canada and 1 more
- Volunteers
- 780 people
- Sponsor
- Michelle Baczynski
Chest Trauma
Bronchoscopy for Thoracic Trauma Patients
The study aims to evaluate the effectiveness of bronchoscopic sputum suction in patients with severe thoracic illness-induced respiratory failure.
- Trial name
- NCT06264856
- Testing
- bronchoscopic sputum suction, negative pressure aspiration suction
- Where
- 2 sites in Taiwan
- Volunteers
- 60 people
- Sponsor
- National Taiwan University Hospital
Rib Fracture
The Analgesic Effect of Retro-laminar Block Versus Paravertebral Block in Patients With Multiple Fracture Ribs
Rib fractures are a common injury, occurring in up to 10% of all trauma patients. Multiple rib fractures can be particularly painful and debilitating, making it difficult for patients to breathe and cough.
- Trial name
- NCT06757803
- Testing
- rertrolaminar block, paravertebral block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Spinal Cord Injury Cervical, Spinal Cord Injury Thoracic
A Study to Evaluate the Safety of a Delivery Device for Administering LCTOPC1 in Participants With Spinal Cord Injury
The DOSED clinical study evaluates the safety and utility of a novel delivery device to deliver LCTOPC1, a cell therapy, to the spinal cord of patients with a spinal cord injury (SCI).
- Conditions
- Spinal Cord Injury Cervical, Spinal Cord Injury Thoracic, Spinal Cord Injury, Acute, Spinal Cord Injury
- Trial name
- DOSED (NCT06841770)
- Testing
- OPC1
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- Lineage Cell Therapeutics, Inc.