Clinical trials: Thoracoabdominal Aneurysm
Aortic Aneurysm, Aortic Aneurysm, Abdominal
Safety and Efficacy of Multiple Overlapping Uncovered Stents for Pararenal Aortic Aneurysm Repair
Complex aortic aneurysms involving major branches have been difficult endovascularly. The primary purposes of this study is to evaluate the safety, feasibility, and efficacy of multiple overlapping uncovered stents in treating…
- Conditions
- Aortic Aneurysm, Aortic Aneurysm, Abdominal, Aortic Aneurysm, Thoracic, Aortic Aneurysm, Thoracoabdominal
- Trial name
- SEMPER (NCT01985906)
- Testing
- Multiple overlapping uncovered stents, Uncovered stents
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Changhai Hospital
Thoracoabdominal Aortic Aneurysms
CUstodiol Versus RInger: whaT Is the Best Agent?
Postoperative renal failure is the most significant risk factor for early mortality after elective surgical repair of thoracoabdominal aortic aneurysms (TAAAs).
- Trial name
- NCT02327611
- Testing
- Custodiol, Enriched Ringer's lactate solution
- Where
- Italy
- Volunteers
- 90 people
- Sponsor
- Scientific Institute San Raffaele
Thoracoabdominal Aortic Aneurysm
Investigation of the Cerebrospinal Fluid and Further Tissue Samples for Biomarker Indicating Spinal Ischemia and Organ Failure in Patients With Thoracoabdominal Aortic Aneurysm
Patients with a thoracoabdominal aortic aneurysm in need of an endovascular or open operative restructuring will be asked to participate in this study.
- Trial name
- TAAA (NCT03093857)
- Testing
- Determination of biomarker
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- RWTH Aachen University
Thoracoabdominal Aortic Aneurysm, Thoracoabdominal; Aortic, Aneurysm, Dissecting
Frailty and Physician Modified Fenestrated Endograft for Thoracoabdominal Aortic Pathologies
The primary objective of this single arm, prospective feasibility study, Impact of Frailty on Clinical Outcomes of Patients Treated for Thoracoabdominal and Complex Abdominal Aortic Aneurysms with Physician-Modified Fenestrated…
- Conditions
- Thoracoabdominal Aortic Aneurysm, Thoracoabdominal; Aortic, Aneurysm, Dissecting, Pararenal Aneurysm, Frailty Syndrome
- Trial name
- NCT04524247
- Testing
- Physician Modified Endografts
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Southern California
Aortic Aneurysm, Abdominal, Aortic Aneurysm, Thoracoabdominal
Clinical Application of the Medyria TrackCath System in Endovascular Repair of Abdominal Aortic Aneurysms (AAA)
Pre-market, single-arm, prospective, open-label, multi-center clinical trial aimed at assessing the safety and the performance of the Medyria TrackCath system in patients undergoing endovascular intervention.
- Conditions
- Aortic Aneurysm, Abdominal, Aortic Aneurysm, Thoracoabdominal, Acute Renal Failure, Acute Kidney Injury
- Trial name
- ACCESS (NCT04190979)
- Testing
- Medyria TrackCath System
- Where
- 4 sites in Germany
- Volunteers
- 40 people
- Sponsor
- Medyria AG
Abdominal Aortic Aneurysm, Pararenal Aortic Aneurysm
GORE® EXCLUDER® Thoracoabdominal Branch Endoprosthesis Post-Approval Study
This study aims to confirm that the benefit-risk assessment of the GORE® EXCLUDER® Thoracoabdominal Branch Endoprosthesis (TAMBE Device) remains positive in real-world use and to ensure the adequacy of the TAMBE Device training…
- Conditions
- Abdominal Aortic Aneurysm, Pararenal Aortic Aneurysm, Thoracoabdominal Aortic Aneurysm
- Trial name
- NCT06578741
- Testing
- GORE® EXCLUDER® Thoracoabdominal Branch Endoprosthesis (TAMBE Device)
- Where
- United States
- Volunteers
- 310 people
- Sponsor
- W.L.Gore & Associates
Thoracoabdominal Aortic Aneurysm
The Safe-line Technique as Additional Attempt to Mitigate Spinal Cord Ischemia After Endovascular Exclusion of TAAA
To assess safety and feasebility of the "safe-line" technique in a multicenter international collaboration.
- Trial name
- Safe-line-tech (NCT05758844)
- Testing
- safe-line technique
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- University Hospital Padova
Thoracoabdominal Aortic Aneurysms
Visceral Manifold Study for the Repair of Thoracoabdominal Aortic Aneurysms
The purpose of this study is to evaluate the use of an investigational device called the ValiantTM Visceral Manifold Thoracoabdominal Stent Graft System for the repair of thoracoabdominal aortic aneurysms (TAAA), which is a…
- Trial name
- NCT03246126
- Testing
- Valiant™Thoracoabdominal Stent Graft System
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- NYU Langone Health
Thoracic Aortic Aneurysm, Respiratory Insufficiency
Immunonutrition and Thoracoabdominal Aorta Aneurysm Repair
The purpose of this study is to determine whether immunonutrition and pre operative nutrition can reduce lenght of respirator support, lenght of stay in the ICU and incidence of post operative infections
- Trial name
- NCT00339053
- Testing
- Immunonutrition ( Impact)
- Where
- Netherlands
- Volunteers
- 142 people
- Sponsor
- St. Antonius Hospital
Thoracoabdominal Aortic Aneurysm
Automated Carbon Dioxide Angiography in Fenestrated/Branched Endovascular Abdominal Aortic Aneurysm Repair
Carbon Dioxide (CO2)-based angiography is a digital subtraction angiography (DSA), where CO2 is used as an intra-arterial contrast agent.
- Trial name
- NCT06103942
- Testing
- CO2 angiography
- Volunteers
- 30 people
- Sponsor
- Uppsala University
Thoracoabdominal Aortic Aneurysm, Pararenal Aortic Aneurysm
TAMBE Japan Post-Marketing Surveillance
To evaluate the safety and efficacy of multi component system (TAMBE device) including GORE® EXCLUDER® Thoracoabdominal Branch Endoprosthesis (Aortic Component; AC) under post-marketing use.
- Trial name
- NCT07147569
- Testing
- GORE® EXCLUDER® Thoracoabdominal Branch Endoprosthesis
- Where
- 5 sites in Japan
- Volunteers
- 100 people
- Sponsor
- W.L.Gore & Associates
Toraco Abdominal Aneurysm
Clinical Study on the Prevention of Surgical Wound Complications for Aneurysmal Thoracic-abdominal Aortic Pathology Using the "PREVENA" System
The patients will be randomized into two groups of 100 subjects each one. One arm will be randomized to treatment with a negative topical pressure system (Sistema Prevena ™); while the other arm ("control group") will be…
- Trial name
- TVAC (NCT03512470)
- Testing
- Sistema Prevena ™(TVAC), Standard medication
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- IRCCS San Raffaele
Thoracic Aortic Aneurysms, Dissecting, Aneurysm
Endovascular Treatment of Thoracic Aortic Disease
The purpose of this study is to assess the role endovascular therapy to treat aortic disease involving the ascending aorta, the aortic arch, and the visceral segment of the aorta (or thoracoabdominal aorta)
- Conditions
- Thoracic Aortic Aneurysms, Dissecting, Aneurysm, Ascending Aorta Aneurysm, Aortic Arch; Aneurysm, Dissecting
- Trial name
- EVOLVE Aorta (NCT00583817)
- Testing
- Endovascular stent-graft implantation
- Where
- 2 sites in United States
- Volunteers
- 170 people
- Sponsor
- Matthew Eagleton
Aortic Aneurysm, Thoracoabdominal, Aortic Diseases
Standardized Physician-modified Fenestrated Endograft Registry
Multicenter retrospective study including all consecutive patients treated by PMEG using a standard modification technique of Valiant Captivia (Medtronic, Minneapolis, MN-USA).
- Trial name
- SPHERE (NCT06358248)
- Testing
- Physician-modification of Valiant Captivia Endograft (Medtronic, Minneapolis, MN-USA).
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- University Hospital Padova
Thoracoabdominal Aneurysm
Registry in Patients With Thoracoabdominal Aneurysms
In this study patients will be observed, who receive a multi-branch stent graft tailored to the patients anatomy for the endovascular treatment of a thoracoabdominal aortic aneurysm Crawford type I, II, III, IV or V.
- Trial name
- CONNECT (NCT03295682)
- Testing
- Endovascular thoracoabdominal aneurysm repair
- Where
- Germany
- Volunteers
- 47 people
- Sponsor
- JOTEC GmbH
Thoracoabdominal Aortic Aneurysms
A PROpensity Score Matching Analysis on ENDovascular vs Open Thoraco-Abdominal Aortic Aneurysm Repair (PRO-ENDO TAAA Study)
The purpose of the registry is to compare the surgical and endovascular approaches to the treatment of thoracoabdominal aortic aneurysms.
- Trial name
- PRO-ENDO TAAA (NCT05266781)
- Testing
- Surgical repair, Endovascular repair
- Where
- Italy
- Volunteers
- 650 people
- Sponsor
- IRCCS San Raffaele
Renal Failure
A Comparison of Renal Perfusion in Thoracoabdominal Aortic Aneurysm (TAAA) Repair
The purpose of this randomized trial was to determine whether renal perfusion with cold blood provides better protection against renal ischemia than perfusion with cold crystalloid in patients undergoing TAAA repair with left…
- Trial name
- NCT00691756
- Testing
- Cold blood renal perfusion, Cold crystalloid renal perfusion
- Where
- United States
- Volunteers
- 172 people
- Sponsor
- Baylor College of Medicine
Thoracoabdominal Aortic Aneurysm
Visceral Manifold Study for the Repair of Thoracoabdominal Aortic Aneurysms
The primary objective of the clinical investigation is to assess the use of the the Visceral Manifold Thoracoabdominal Aortic Aneurysms (VTAAA) stent graft system to repair thoracoabdominal aortic aneurysms in patients having…
- Trial name
- NCT03113383
- Testing
- Thoracoabdominal Aortic Aneurysm Repair
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Vanderbilt University Medical Center
Thoracoabdominal Aneurysm, Juxtarenal Aortic Aneurysm
Safety and Effectiveness of Surgeon-Modified Stent Grafts forTreatment of Complex Aortic Aneurysms
The primary objective of the present study is to evaluate the safety, effectiveness, and clinical outcomes of surgeon-modified fenestrated stent grafts used to treat patients with failed previous infrarenal repairs (failed EVAR)…
- Conditions
- Thoracoabdominal Aneurysm, Juxtarenal Aortic Aneurysm, Pararenal Aneurysm, Aortic Aneurysm
- Trial name
- Assets (NCT05531084)
- Testing
- Surgeon-Modified fenestrated stent grafts using Cook Zenith Platform (Zfen, TX2, Alpha Thoracic Endovascular Graft and Zenith Flex)
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Jesse Manunga, MD
Aortic Aneurysm, Thoracoabdominal, Aortic Aneurysm, Abdominal
Effect of Remimazolam Versus Propofol Total Intravenous Anesthesia on Intraoperative Hemodynamic Stability in Patients Undergoing Thoracic or Abdominal Endovascular Aortic Repair
The purpose of this study is to compare two intravenous anesthetics, remimazolam and propofol, for their effects on intraoperative hemodynamic stability in patients undergoing thoracic or abdominal endovascular aortic repair.
- Conditions
- Aortic Aneurysm, Thoracoabdominal, Aortic Aneurysm, Abdominal, Intraoperative Hypotension, Hemodynamic Instability During Anesthesia
- Trial name
- NCT07806006
- Testing
- Remimazolam Besylate, propofol
- Where
- South Korea
- Volunteers
- 44 people
- Sponsor
- Seoul National University Hospital