Clinical trials: Thoracoabdominal Aortic Aneurysm
Juxtarenal Aortic Aneurysm, Thoracoabdominal Aortic Aneurysm
Modified Preloaded System for Renal Arteries in Fenestrated Endografting (MPSRA)
Advanced Endovascular repair of aneurysms and dissections involving thoraco-abdominal (type I-IV) and complex abdominal (juxta and para-renal) aorta is a ground-gaining procedure allowing favorable results in high surgical risk…
- Conditions
- Juxtarenal Aortic Aneurysm, Thoracoabdominal Aortic Aneurysm, Pararenal Aortic Aneurysm, Aortic Aneurysm, Thoracoabdominal
- Trial name
- MPSRA (NCT05224219)
- Where
- Italy
- Volunteers
- 35 people
- Sponsor
- University of Bologna
Aortic Aneurysm, Spinal Ischaemia
Organ Failure After Advanced Endovascular Thoracoabdominal Aortic Surgery
The purpose of this study is to investigate the mortality and frequency of organ dysfunction in patients after endovascular thoracoabdominal aortic surgery, and to search for biomarkers of organ dysfunction, in particular the…
- Conditions
- Aortic Aneurysm, Spinal Ischaemia, Gastrointestinal Ischaemia
- Trial name
- ODEA (NCT03136536)
- Where
- Sweden
- Volunteers
- 60 people
- Sponsor
- Region Örebro County
Thoracoabdominal Aortic Aneurysm, Ruptured Thoracic Aneurysm
Endovascular Aortic Repair of Free and Contained Ruptured Thoraco-Abdominal Aortic Aneurysm
Ruptured thoracoabdominal aortic aneurysm (TAAA) represents an emergency medical challenge that needs to be treated promptly. Over the past years different endovascular techniques have emerged such as fenestrated or branched…
- Conditions
- Thoracoabdominal Aortic Aneurysm, Ruptured Thoracic Aneurysm, Ruptured Aortic Aneurysm, Thoracoabdominal Aortic Aneurysm, Ruptured
- Trial name
- REVAR-TAAA (NCT05956873)
- Testing
- REVAR
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- University of Bologna
Thoracoabdominal Aortic Aneurysm, Aortic Arch Aneurysm
Evaluation of Branch Endografts in the Treatment of Aortic Aneurysms
Zenith t-Branch Study Cohort: The purpose of this study is to collect information on the Cook Zenith t-Branch endovascular stent-graft system and the Terumo Arch Branch for the treatment of aortic aneurysms.
- Trial name
- NCT01524211
- Testing
- Zenith® t-Branch, Terumo Arch Branch
- Where
- United States
- Volunteers
- 235 people
- Sponsor
- Baptist Health South Florida
Thoracoabdominal Aneurysm
Evaluation of the GORE® EXCLUDER® Thoracoabdominal Branch Endoprosthesis in the Treatment of the Thoracoabdominal and Pararenal Aortic Aneurysms (TAMBE)
Expanded access tothe GORE® EXCLUDER® Thoracoabdominal Branch Endoprosthesis is safe and effective in the treatment of thoracoabdominal and pararenal aneurysms.
- Trial name
- TAMBE (NCT05442489)
- Testing
- GORE Excluder Thoracoabdominal Branch Endoprosthesis
- Where
- 41 sites in United States
- Sponsor
- W.L.Gore & Associates
Thoracoabdominal Aortic Aneurysms
Visceral Manifold Study for the Repair of TAAA
The outcomes from prior clinical evaluation of the study device, including successfully treating 99% (84/85) of the intended target vessels and 96% (27/28) limb patency observed at one year, demonstrate the potential benefits of…
- Trial name
- NCT03075748
- Testing
- TAAA Debranching Stent Graft System
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- University of South Florida
Aortic Aneurysm, Thoracoabdominal
Post-market Observational Study Zenith® t-Branch™
The Zenith® t-Branch™ Thoracoabdominal Endovascular Graft Study is a post-market observational study to evaluate the performance of the Zenith® t-Branch™ in the treatment of thoracoabdominal aortic aneurysms in routine care.
- Trial name
- NCT02104089
- Testing
- Zenith® t-Branch™ Thoracoabdominal Endovascular Graft
- Where
- 3 sites in Germany, Sweden
- Volunteers
- 80 people
- Sponsor
- Cook Group Incorporated
Aortic Aneurysm
Safety and Effectiveness of Physician-Modified Fenestrated and Branched Aortic Endografting for the Treatment of Thoracoabdominal and Pararenal Aortic Aneurysms
The primary clinical objective of this study is to evaluate the safety and effectiveness of a physician-modified, fenestrated and branched aortic endoprosthesis for the treatment of thoracoabdominal aortic aneurysms (TAAAs).
- Trial name
- NCT06501872
- Testing
- Physician-modified aortic endograft
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Bjoern D. Suckow
Aortic Aneurysm, Abdominal, Aortic Aneurysm, Thoracoabdominal
Evaluation of the Bifurcated Multilayer Flow Modulator for the Treatment of Abdominal Aortic Aneurysm
The study purpose is to determine the safety and efficacy of the BMFM used for the endovascular treatment of aortic aneurysm involving iliac arteries.
- Trial name
- STREAMLINER (NCT03024554)
- Testing
- Implantation of the Bifurcated Multilayer Flow Modulator
- Where
- 7 sites in Belgium, Bulgaria and 3 more
- Volunteers
- 42 people
- Sponsor
- Cardiatis
Aortic Aneurysm, Thoracoabdominal
Paraplegia Prevention in Aortic Aneurysm Repair by Thoracoabdominal Staging
Aortic aneurysms represent the most common and dangerous aortic diseases. Although conventional aortic repair techniques cure the disease, there is a high risk of paraplegia particularly in extensive thoracoabdominal aneurysms…
- Trial name
- PAPAartis (NCT03434314)
- Testing
- Minimally-Invasive Segmental Artery Coil-Embolization
- Where
- 29 sites in Austria, France and 7 more
- Volunteers
- 500 people
- Sponsor
- University of Leipzig
Thoracoabdominal Aortic Aneurysm
Visceral Manifold Study for the Repair of Thoracoabdominal Aortic Aneurysms
The primary objective of the clinical investigation is to assess the use of the the Visceral Manifold Thoracoabdominal Aortic Aneurysms (VTAAA) stent graft system to repair thoracoabdominal aortic aneurysms in patients having…
- Trial name
- NCT03113383
- Testing
- Thoracoabdominal Aortic Aneurysm Repair
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Vanderbilt University Medical Center
Toraco Abdominal Aneurysm
Clinical Study on the Prevention of Surgical Wound Complications for Aneurysmal Thoracic-abdominal Aortic Pathology Using the "PREVENA" System
The patients will be randomized into two groups of 100 subjects each one. One arm will be randomized to treatment with a negative topical pressure system (Sistema Prevena ™); while the other arm ("control group") will be…
- Trial name
- TVAC (NCT03512470)
- Testing
- Sistema Prevena ™(TVAC), Standard medication
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- IRCCS San Raffaele
Type B Acute Aortic Syndrome, Thoracic and Thoracoabdominal Aneurysms With Crawford Extent I, II, III, or IV
A Standard Carbon Dioxide Flushing Protocol to Reduce Air Embolization During Thoracic Endovascular Aortic Repair
FlushTEVAR is a non-profit, interventional, randomized, controlled, single-blind, national multicenter study promoted by the University of Bologna and coordinated by the Vascular Surgery Unit of IRCCS Azienda…
- Trial name
- FlushTEVAR (NCT07734584)
- Testing
- Carbon dioxide pre-implant endograft flushing followed by saline flushing, Saline endograft flushing
- Where
- 4 sites in Italy
- Volunteers
- 90 people
- Sponsor
- University of Bologna
Aortic Aneurysm, Thoracoabdominal, Aortic Diseases
Standardized Physician-modified Fenestrated Endograft Registry
Multicenter retrospective study including all consecutive patients treated by PMEG using a standard modification technique of Valiant Captivia (Medtronic, Minneapolis, MN-USA).
- Trial name
- SPHERE (NCT06358248)
- Testing
- Physician-modification of Valiant Captivia Endograft (Medtronic, Minneapolis, MN-USA).
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- University Hospital Padova
Abdominal Aortic Aneurysm, Thoracoabdominal Aortic Aneurysm
Safety and Efficacy of Endovascular Repair of Complex Aortic Pathology With Physician-modified Endovascular Grafts (PMEGs)
The primary objective of this study is to examine the safety and effectiveness of physician-modified endovascular grafts (PMEGs) for endovascular repair of complex aortic pathology in high-risk patients.
- Conditions
- Abdominal Aortic Aneurysm, Thoracoabdominal Aortic Aneurysm, Aortic Dissection
- Trial name
- NCT04746677
- Testing
- Endovascular aortic repair with a physician-modified endovascular graft (PMEG), TREO graft
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- Beth Israel Deaconess Medical Center
Aortic Aneurysm, Thoracoabdominal
Physician-Modified Fenestrated and Branched Aortic Endografting for TAAA
The primary clinical objective of this study is to evaluate the safety and effectiveness of a physician-modified, fenestrated and branched aortic endoprosthesis for the treatment of thoracoabdominal aortic aneurysms (TAAAs).
- Trial name
- NCT02989948
- Testing
- Physician-modified aortic endograft
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- Yale University
Renal Failure
A Comparison of Renal Perfusion in Thoracoabdominal Aortic Aneurysm (TAAA) Repair
The purpose of this randomized trial was to determine whether renal perfusion with cold blood provides better protection against renal ischemia than perfusion with cold crystalloid in patients undergoing TAAA repair with left…
- Trial name
- NCT00691756
- Testing
- Cold blood renal perfusion, Cold crystalloid renal perfusion
- Where
- United States
- Volunteers
- 172 people
- Sponsor
- Baylor College of Medicine