Clinical trials: Thoracolumbar, open to volunteers
Healty Volunteers
Acute Effects of Thoracolumbar Fascia Myofascial Release on Cortical Activity
This study will examine the immediate (acute) effects of a single myofascial release technique applied to the thoracolumbar fascia on brain activity in healthy young adults aged 18-25.
- Trial name
- MFR-EEG (NCT07728617)
- Testing
- Thoracolumbar Fascia Myofascial Release (Pilat MIF Crossed-Hands Technique)
- Where
- Turkey (Türkiye)
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Hitit University
Thoracolumbar Low-energy Vertebral Compression Fractures
Large-Scale Evaluation of a Clinical Decision Tree for the Management of Low-Energy Thoracic and Lumbar Vertebral Compression Fractures.
Percutaneous vertebroplasty is widely used for low-energy vertebral compression fractures, but its clinical benefits remain debated.
- Trial name
- PALMTREE (NCT07706439)
- Where
- France
- Volunteers
- 400 people
- Sponsor
- University Hospital, Grenoble
Thoracolumbar Burst Fractures
Vertebral Augmentation and Percutaneous Fixation for Thoracolumbar Burst Fractures Requiring Corpectomy
This study evaluates minimally invasive vertebral augmentation combined with percutaneous fixation for the treatment of severe thoracolumbar burst fractures.
- Trial name
- EXVERCOR (NCT07645092)
- Volunteers
- 30 people
- Sponsor
- University Hospital, Grenoble
Forward Head Posture
Effect of Adding Thoracolumbar Fascia Release by IASTM to Conventional Treatment on Craniovertebral Angle in Forward Head Subjects
The Posture Committee of the American Academy of Orthopedic Surgery defines good posture as "that state of muscular and skeletal balance that protects the supporting structures of the body against injury or progressive deformity…
- Trial name
- IASTM (NCT07605650)
- Testing
- Instrument assisted soft tissue moblization
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Postoperative Pain, Spinal Fusion Surgery
TLIP Block Versus Retrolaminar Block on Quality of Recovery After Posterior Lumbar Spine Fusion Surgery
This prospective randomized controlled study aims to compare the effects of ultrasound-guided thoracolumbar interfascial plane (TLIP) block versus retrolaminar block on postoperative quality of recovery in patients undergoing…
- Conditions
- Postoperative Pain, Spinal Fusion Surgery, Degenerative Lumbar Spine Diseases
- Trial name
- TLIP-RLB-QoR (NCT07609212)
- Testing
- Thoracolumbar interfascial plane block, Retrolaminar block
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Assiut University
Subacromial Impingement Syndrome, Shoulder Pain
Effects of Kinesio Taping on Thoracolumbar Fascia Flexibility in Patients With Shoulder Injury
The aim of this randomized controlled trial is to investigate the acute effects of fascia correction Kinesio Taping applied to the thoracolumbar fascia (TLF) in individuals with Subacromial Impingement Syndrome (SIS).
- Trial name
- NCT07624136
- Testing
- kinesio taping
- Where
- Turkey (Türkiye)
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Kübra Sarıoğlu
Chronic Non Specific Mechanical Low Back Pain
Effect of Lumbar Stabilization Exercises With and Without YTWL (Scapular Stabilization Exercises) on Reducing Chronic Low Back Pain and Related Disability. A Randomized Clinical Trial,
Chronic low back pain is a common problem that can make daily activities difficult. Exercises that strengthen and stabilize the lower back are commonly used to reduce pain and improve movement.
- Trial name
- A RCT (NCT07845760)
- Testing
- Lumbar Stabilization Exercises and heating pad, Scapular Stabilization Exercises (YTWL) + Lumbar Stabilization Exercises + Heating Pad
- Where
- Pakistan
- Volunteers
- 70 people
- Sponsor
- Dow University of Health Sciences
Degenerative Disc Disease, Degenerative Scoliosis
Clinical Outcome Measure at Stryker Spine
This is a multicenter, prospective, retrospective, Post Market Clinical Follow-up (PMCF) study in subjects who have undergone or will undergo surgery utilizing one or more Stryker devices according to Stryker cleared Instructions…
- Trial name
- COMPASS (NCT06226272)
- Testing
- Spinal Fusion, Spinal Deformities Correction
- Where
- 7 sites in United States
- Volunteers
- 5,222 people
- Sponsor
- VB Spine, LLC
Lumbar Disc Herniation, Postoperative Pain
Comparison of TLIP Block and QIP Block for Postoperative Analgesia After Lumbar Spine Surgery
This study compares two regional anesthesia techniques used for pain control after lumbar spine surgery: the classic thoracolumbar interfascial plane (TLIP) block and the quadratus lumborum-iliac plane (QIP) block.
- Trial name
- TLIP-QIP (NCT07750418)
- Testing
- Thoracolumbar Interfascial Plane (TLIP) Block of bupivacaine, Quadratus Lumborum-Iliac Plane (QIP) Block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Vezirköprü State Hospital
Scoliosis
Biomechanical Study of Lever Positioning Manipulation on Scoliosis
Research background Scoliosis is a common three-dimensional spinal deformity, especially in adolescents. In severe cases, it can lead to thoracic deformation and cardiopulmonary dysfunction.
- Trial name
- NCT07325045
- Testing
- Lever positioning manipulation
- Where
- China
- Volunteers
- 30 people
- Sponsor
- The Third Affiliated hospital of Zhejiang Chinese Medical University
Chronic Low Back Pain (CLBP), Musculoskeletal Pain
Virtual Reality-Based Rehabilitation in Chronic Low Back Pain: Effects on Muscle Architecture, Balance, and Satisfaction (VR-LBPREHAB)
Chronic low back pain is a common musculoskeletal disorder that causes pain, disability, and reduced quality of life. It is often related to changes in trunk muscle function, thoracolumbar fascia morphology, and impaired balance…
- Conditions
- Chronic Low Back Pain (CLBP), Musculoskeletal Pain, Postural Balance, Exercise Therapy
- Trial name
- VR-LBPREHAB (NCT07172828)
- Testing
- Virtual Reality-Based Rehabilitation, Conventional Motor Control Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Hacettepe University
Thoracolumbar Compression Fractures
Short Segment Versus Long Segment Transpedicular Screw Fixation in the Correction and Preservation of AO-Type B Thoracolumbar Fracture Alignment: A Comparative Study
To compare the radiological, clinical and functional outcomes of short-segment versus long-segment transpediclular screw fixation in patients with thoracolumbar fractures AO-type B.
- Trial name
- NCT07777653
- Testing
- Short Segment Versus Long Segment Transpedicular Screw Fixation in the Correction and Preservation of AO-Type B Thoracolumbar Fracture Alignment: A Comparative Study
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Open Posterior Thoracolumbar Spinal Fusion Procedure
Single Versus Multi-Dose Oral and Intravenous Tranexamic Acid Patients at High Risk for Blood Transfusion After Spine Surgery
As tranexamic acid (TXA) becomes more prevalent, all patients are receiving the same dose and method of delivery regardless of their pre-operative risk of transfusion.
- Trial name
- NCT03849443
- Testing
- Tranexamic Acid Injectable Product (1000 mg intravenous bolus), Vitamin C 250 MG Oral Tablet, Tranexamic Acid 650Mg Tablet
- Where
- United States
- Volunteers
- 604 people
- Sponsor
- Rush University Medical Center
Osteoporotic Fractures, Osteoporosis
The Osteoporotic Fracture Classification-based Scoring System for Treatment Decision in Thoracolumbar Osteoporotic Fractures
This is an international multicenter prospective observational study. Patients with radiologically confirmed, symptomatic, single- or multilevel contiguous TL (from T1 to L5) fractures as a result of primary osteoporosis will be…
- Trial name
- NCT07027306
- Testing
- Posterior stabilization (pedicle screws)
- Where
- 15 sites in United States, Argentina and 12 more
- Volunteers
- 648 people
- Sponsor
- AO Foundation, AO Spine
Low Back Pain, Chronic Low-back Pain
Physical Exam, Static & Dynamic Ultrasound Assessment, & Treatment of Thoracolumbar Fascia (TLF) Mediated Low Back Pain
This Study is for our continued study of the Thoracolumbar Fascia (TFL) in patients with and without low back pain by our experienced multidisciplinary team: Vincent Wang PhD, VT Biomedical Engineering \& Mechanics (BEAM).
- Conditions
- Low Back Pain, Chronic Low-back Pain, Acute Low Back Pain
- Trial name
- NCT06818175
- Testing
- Ultrsound Guided Hydrodissection of the Thoracolumbar Fascia, Osteopathic Manipulative Treatment (OMT)
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Edward Via Virginia College of Osteopathic Medicine
Cerebral Palsy (CP), Rehabilitation
Trial Examines Short-term Effects of Hippotherapy on Fascia Properties and Quality of Life in Children With CP.
The effects of hippotherapy on gross motor function, balance, and spasticity in children with cerebral palsy (CP) are well-documented, but its impact on the thoracolumbar fascia (TLF) remains unexplored area to date.
- Conditions
- Cerebral Palsy (CP), Rehabilitation, Motor Coordination or Function, Hippotherapy
- Trial name
- HYPPOTER25 (NCT07134582)
- Testing
- Hippotherapy 1x/week, Hippotherapy 2x/week
- Where
- Slovenia
- Volunteers
- 27 people
- Sponsor
- University Medical Centre Ljubljana
Thoracolumbar, Fractures in the Elderly
Monoaxial vs. Polyaxial Percutaneous Hybrid Stabilization
Vertebral body fractures in older adults mostly affect the thoracolumbar junction and are challenging to treat due to osteoporosis and other comorbidities.
- Trial name
- NCT07408726
- Testing
- Monoaxial instrumentation - the M.U.S.T. Monoaxial Pedicle Screw Cannulated (Medacta International SA, Switzerland), Polyaxial instrumentation - the M.U.S.T. LT Pedicle Screw System (Medacta International SA, Switzerland)
- Where
- Austria
- Volunteers
- 44 people
- Sponsor
- Medical University Innsbruck
Spine Fracture, Orthosis
ORthosis vs No Orthosis After Surgically Treated Traumatic Thoracolumbar Fractures
Rationale: There is no evidence in the current literature regarding the additional value of an orthosis after surgically treated thoracolumbar spine fractures.
- Conditions
- Spine Fracture, Orthosis, Traumatic Fracture, Posterior Fixation
- Trial name
- ORNOT (NCT03097081)
- Testing
- No orthosis, Orthosis
- Where
- Netherlands
- Volunteers
- 45 people
- Sponsor
- Amsterdam UMC, location VUmc
Spine Fracture, Osteoporosis
Controlled Reduction of AO Spine B3 Fractures in Ankylosing Spinal Disorders Using an Inflatable Positioning Device: Technical Note and Retrospective Single-centre Case Series
Retrospective observational
- Conditions
- Spine Fracture, Osteoporosis, Spondylitis, Ankylosing
- Trial name
- NCT07847320
- Volunteers
- 23 people
- Sponsor
- Diakonie-Klinikum Stuttgart
Postoperative Pain Management
mTLIP vs QIPB for Postoperative Analgesia in Lumbar Microdiscectomy Surgery
The aim of this prospective randomized clinical study is to compare the analgesic efficacy and side effects of modified thoracolumbar interfascial plane block and quadroiliac plane block applied preoperatively in patients…
- Trial name
- NCT07480278
- Testing
- Modified Thoracolumbar Interfascial Plane Block (mTLIP), Quadro-Iliac Plane Block (QIPB)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Bursa City Hospital