Clinical trials: Thoracolumbar Burst Fracture
Single Level Stable Thoracolumbar Fracture Type AO A3, Multiple Level Stable Thoracolumbar Fracture Type AO A3
Spine FA3 - a Prospective, International, Multicenter Cohort Study on Treatment of of AO A3 Thoracolumbar Fractures
Thoracolumbar fractures are the most common spinal fractures with an average annual incidence between 18 and 30 per 100'000 inhabitants. The majority of these fractures are AO type A3 ("burst fractures").
- Trial name
- FA3 (NCT01751633)
- Testing
- Surgical, Conservative treatment
- Where
- 8 sites in Brazil, Chile and 4 more
- Volunteers
- 38 people
- Sponsor
- AO Clinical Investigation and Publishing Documentation
Surgery
Enhancing Thoracolumbar Burst Fracture Treatment
The optimal treatment for neurologically intact thoracolumbar fractures remains controversial. Percutaneous pedicle screw fixation (PPSF) has been proposed for these fractures; however, achieving satisfactory reduction can be…
- Trial name
- NCT06561997
- Testing
- Robot-assisted, Free-hand
- Where
- China
- Volunteers
- 182 people
- Sponsor
- Peng Liu
SPINAL Fracture, Burst Fracture
Surgical Versus Non-Surgical Treatment of Thoracolumbar Burst Fracture
Treatment for acute traumatic thoracolumbar burst fractures differs significantly across the world in patients without neurological impairments and without damage to the posterior column of the spine.
- Conditions
- SPINAL Fracture, Burst Fracture, Spinal Instability of Thoracolumbar Region
- Trial name
- A34RCT (NCT05769114)
- Testing
- Surgical stabilization
- Where
- 2 sites in Switzerland
- Volunteers
- 52 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Burst Fracture
Thoracolumbar Burst Fracture Treated With Pedicle Screws: Radiographic Outcomes
The surgical results of thoracolumbar and lumbar burst fracture have been reported to be comparable between patients with and without fusion in a midterm follow-up.
- Trial name
- NCT01979198
- Where
- Taiwan
- Volunteers
- 48 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Thoracic Fracture, Lumbar Fracture
Effect of Bracing Versus No Bracing in Stable Thoracolumbar Compression and Burst Fractures
Spinal orthoses have been used in the treatment of non-operative thoracic and lumbar fractures with much success. However, there has been increasing questioning as to wether or not the orthotics are necessary to have a good…
- Conditions
- Thoracic Fracture, Lumbar Fracture, Compression Fracture of Thoracic Vertebral Body, Compression Fracture of Lumbar Spine
- Trial name
- NCT03952182
- Testing
- Spinal Orthosis (LSO, TLSO), No orthosis
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- St. Louis University
Thoracolumbar Burst Fracture
Thoracolumbar Burst Fractures Study Comparing Surgical Versus Non-surgical Treatment
Thoracolumbar (TL) burst fractures in neurologically intact patients account for approximately 45% of all TL spine injuries. Despite being common fractures, there is significant variability in treatment recommendations…
- Trial name
- NCT02827214
- Where
- 14 sites in United States, Australia and 8 more
- Volunteers
- 213 people
- Sponsor
- AO Innovation Translation Center
Thoracolumbar Burst Fracture
Comparison of Posterior Fixation Alone and Combined With Articular Process Fusion in Thoracolumbar Burst Fractures
Nearly 90% of all spinal fractures occur in the thoracolumbar region, and burst fractures are composed of 15% of such injuries. But the treatment of thoracolumbar fractures remains controversial.
- Trial name
- NCT01864785
- Testing
- Fixation Combined With Fusion, Fixation Alone
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Jinling Hospital, China
Thoracolumbar Burst Fracture
StUdy oN Burst Fractures (SunBurst)
Thoracolumbar (TL) burst fractures are seen in all ages and usually associated with high-energy trauma. Treatment include both surgical and non-surgical options.
- Trial name
- SunBurst (NCT05003180)
- Testing
- Surgical stabilization
- Where
- 17 sites in Norway, Sweden
- Volunteers
- 202 people
- Sponsor
- Uppsala University
Thoracolumbar Burst Fractures Without Neurologic Deficit
Brace Versus No Brace for the Treatment of Thoracolumbar Burst Fractures Without Neurologic Injury
Braces have been used o treat stable (not requiring surgery) burst fractures with much success. Recently questions have been raised in regards to the importance of the brace.
- Trial name
- NCT01741168
- Testing
- TLSO, No Orthosis
- Where
- Canada
- Volunteers
- 97 people
- Sponsor
- The London Spine Centre
Posterior Short-segment Pedicle Instrumentation
A Modified Placement of Two Additional Pedicle Screws at the Fracture Level for the Treatment of Thoracolumbar Burst Fractures--a Study Protocol of a Randomised Controlled Trial
Controversies exist about the best treatment of burst fractures of the thoracolumbar spine. Adding screws in fractured segment has been proved in many literatures that can improve construct stiffness but sometimes aggravate the…
- Trial name
- NCT03384368
- Testing
- fractured level screws-distraction
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
SPINAL Fracture
Calcium Phosphate Versus PMMA Cement in Thoracolumbar Fractures
Patients at the age of 50 or older presenting with thoracolumbar fractures including segments TH 6-L5 and A3/A4 fractures according to the AO Spine fracture classification after the acute trauma and planned surgery within 3 weeks…
- Trial name
- CaPvsPMMA (NCT04743869)
- Testing
- Kyphos FS™ Bone Substitute, KYPHON ActivOs® Bone Cement with Hydroxyapatite
- Volunteers
- 85 people
- Sponsor
- Medical University of Graz
Evaluation of the Validity of Thoracolumbar AO Spine Injury Score (TL AOSIS) in A3 and A4 Fractures
Thoracolumbar Burst Fracture Management: Randomized Trial
Between December 2019 to December 2022, patients presenting to causalty department with TL fracture type A3 and A4 with a TL AOSIS scores of 4 and 5 were randomly managed either by conservative or operative management.
- Trial name
- NCT07192250
- Testing
- short segment TPF, conservative management
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Ahmed Hamed Kassem Abdelaal
Thoracic Spine Fracture, Lumbar; Spine, Fracture
Effectiveness of Conservative Treatment in Patients With Thoracic and Lumbar Fractures Without Neurological Deficit
The goal of this observational study is to compare the long-term clinical outcomes of two treatment methods (conservative therapy and surgical treatment) in patients with fractures of the thoracic and lumbar spine without…
- Conditions
- Thoracic Spine Fracture, Lumbar; Spine, Fracture, Thoracolumbar Burst Fracture, Fracture of Spine, Level Unspecified
- Trial name
- NCT06059820
- Testing
- rehabilitation treatment, Spine fusion
- Where
- 2 sites in Russia
- Volunteers
- 40 people
- Sponsor
- Sklifosovsky Institute of Emergency Care
Thoracolumbar Burst Fractures
Vertebral Augmentation and Percutaneous Fixation for Thoracolumbar Burst Fractures Requiring Corpectomy
This study evaluates minimally invasive vertebral augmentation combined with percutaneous fixation for the treatment of severe thoracolumbar burst fractures.
- Trial name
- EXVERCOR (NCT07645092)
- Volunteers
- 30 people
- Sponsor
- University Hospital, Grenoble