Clinical trials: Thoracolumbar Spinal Fusion
Drainage, Spinal (Fusion) Surgery
ESTIMATION OF INCREASED SURGICAL DRAINAGE OUTPUT FOLLOWING THORACOLUMBAR SURGERY
In a study involving neurosurgeons worldwide, it was reported that most surgeons preferred the use of drains (186, 80.5%) and subfascial drains (169, 73.2%), with 52.87% of surgeons discontinuing drains based on time and 27.7%…
- Trial name
- NCT07390058
- Volunteers
- 326 people
- Sponsor
- AKİF BULUT
Intervertebral Disc Degeneration
Safety and Performance of the SpineVision Posterior Fixation Systems in Thoracolumbar Spinal Treatment
The goal of this observational study is to confirm the safety and performance of the three (3) Spinevision posterior fixations systems Lumis®, Plus® and Ulis® , in the treatment of patient suffering from thoracolumbar spinal…
- Trial name
- FixedD3 (NCT06342765)
- Testing
- Pedicle fixation surgery
- Where
- 3 sites in France
- Volunteers
- 330 people
- Sponsor
- SPINEVISION SAS
Degenerative Disc Disease, Degenerative Scoliosis
Clinical Outcome Measure at Stryker Spine
This is a multicenter, prospective, retrospective, Post Market Clinical Follow-up (PMCF) study in subjects who have undergone or will undergo surgery utilizing one or more Stryker devices according to Stryker cleared Instructions…
- Trial name
- COMPASS (NCT06226272)
- Testing
- Spinal Fusion, Spinal Deformities Correction
- Where
- 7 sites in United States
- Volunteers
- 5,222 people
- Sponsor
- VB Spine, LLC
Single Level Stable Thoracolumbar Fracture Type AO A3, Multiple Level Stable Thoracolumbar Fracture Type AO A3
Spine FA3 - a Prospective, International, Multicenter Cohort Study on Treatment of of AO A3 Thoracolumbar Fractures
Thoracolumbar fractures are the most common spinal fractures with an average annual incidence between 18 and 30 per 100'000 inhabitants. The majority of these fractures are AO type A3 ("burst fractures").
- Trial name
- FA3 (NCT01751633)
- Testing
- Surgical, Conservative treatment
- Where
- 8 sites in Brazil, Chile and 4 more
- Volunteers
- 38 people
- Sponsor
- AO Clinical Investigation and Publishing Documentation
SPINAL Fracture, Vertebral Fractures
Clinical Study With a Robotic Assistant in Patients Requiring a Spinal Transpedicular Fixation
This multicenter, non-comparative clinical trial, led by two principal investigators in Spain, aims to evaluate the safety and performance of a robotic assistant, based on a electromechanical tracking system, in patients…
- Conditions
- SPINAL Fracture, Vertebral Fractures, Spinal Stenosis, Kyphosis
- Trial name
- NCT06153511
- Testing
- Robot assisted spinal transpedicular fixation
- Where
- Spain
- Volunteers
- 13 people
- Sponsor
- Cyber Surgery S.L.
Adolescent Idiopathic Scoliosis
The Relaionship Between Sagittal Spinal Parameters and PSI
Adolescent idiopathic scoliosis (AIS) is the most common three-dimensional deformity of the spine that is typically characterized by curvature in both the coronal and sagittal planes.
- Trial name
- NCT06085651
- Testing
- Selective thoracolumbar fusion (STLF) surgery
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Spondylodiscitis
CORset Versus OstéoSynthese in Adult Pyogenic Spondylodiscitis
Pyogenic spondylitis in adults is usually treated by antibiotics according to bacteria evidenced in a diagnostic intervertebral disc puncture.
- Trial name
- COROSIVE (NCT03524209)
- Testing
- Percutaneous instrumentation of the thoracolumbar spine, Brace
- Where
- 15 sites in France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Strasbourg, France
Thoracolumbar Spinal Fusion
Retrospective Evaluation of Upper Instrumented Vertebrae (UIV) Screw Loosening Following Spine Surgery
The REESE study is looking at information from past spine surgeries to learn how often screws placed at the top of a spinal fusion become loose over time.
- Trial name
- REESE (NCT07838571)
- Where
- 3 sites in United States
- Volunteers
- 400 people
- Sponsor
- Ohio State University
Spinal Deformity, Spinal Instability
RCT of AttraX® Putty vs. Autograft in Instrumented Posterolateral Spinal Fusion
The purpose of this study is to demonstrate the non-inferiority of AttraX® Putty as a bone graft substitute for autograft in instrumented posterolateral fusion of the thoracolumbar spine, in terms of efficacy and safety.
- Conditions
- Spinal Deformity, Spinal Instability, Instrumented Spinal Fusion
- Trial name
- AxA (NCT01982045)
- Testing
- AttraX® Putty, Autologous bone graft
- Where
- 4 sites in Netherlands
- Volunteers
- 100 people
- Sponsor
- UMC Utrecht
Thoracic Spine Fracture, Lumbar; Spine, Fracture
Effectiveness of Conservative Treatment in Patients With Thoracic and Lumbar Fractures Without Neurological Deficit
The goal of this observational study is to compare the long-term clinical outcomes of two treatment methods (conservative therapy and surgical treatment) in patients with fractures of the thoracic and lumbar spine without…
- Conditions
- Thoracic Spine Fracture, Lumbar; Spine, Fracture, Thoracolumbar Burst Fracture, Fracture of Spine, Level Unspecified
- Trial name
- NCT06059820
- Testing
- rehabilitation treatment, Spine fusion
- Where
- 2 sites in Russia
- Volunteers
- 40 people
- Sponsor
- Sklifosovsky Institute of Emergency Care
Delirium, Pain, Back
Regional Nerve Blocks to Improve Analgesia and Recovery in Older Adults Undergoing Spinal Fusion
This initial study is a feasibility study for implementing thoracolumbar interfascial plane, or TLIP, blocks in older adults undergoing spinal fusion. TLIP blocks are done by using anesthesia.
- Conditions
- Delirium, Pain, Back, Spinal Fusion, Thoracolumbar Interfascial Plane Block
- Trial name
- NCT05461092
- Testing
- Thoracolumbar Interfascial Plane (TLIP) Block of bupivacaine, Blood Test, 3D CAM Delirium Severity Scoring
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Iowa
Thoracolumbar Spinal Fusions
Ketorolac on Posterior Thoracolumbar Spinal Fusions
To determine is low-dose ketorolac use in the early post-operative period (within 48 hours) provides adequate analgesia without long term adverse effect on spinal fusion rates when compared to post-operative analgesia without the…
- Trial name
- NCT03278691
- Testing
- Saline, Ketorolac
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Lumbar Degenerative Disc Disease
Prospective Study of Thoracolumbar Spinal Fusion Graft
This study is a single-center, prospective randomized clinical study intended to compare and evaluate the efficacy of subjects who are treated with bone marrow aspirate concentrate (BMAC) and allograft to iliac crest bone grafts…
- Trial name
- BMAC (NCT02297256)
- Testing
- BMAC & Allograft, Iliac Crest Bone Graft
- Where
- 3 sites in United States
- Volunteers
- 17 people
- Sponsor
- NYU Langone Health
Proximal Junctional Kyphosis, Spino-pelvic Alignment
MSK Validation Study
Spinal posture and imbalance are known to be related to increased muscle expenditure, with narrow "cone of economy" of muscle effort defining the most comfortable postures.
- Conditions
- Proximal Junctional Kyphosis, Spino-pelvic Alignment, Thoracolumbar Spinal Fusion
- Trial name
- MSK (NCT04422288)
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- NuVasive
Spinal Fusion, Postoperative Recovery
Swimming-Based Rehabilitation for Recovery After Thoracolumbar Spinal Fusion
This study evaluates the effectiveness and safety of a structured swimming-based rehabilitation program in patients undergoing thoracolumbar spinal fusion.
- Conditions
- Spinal Fusion, Postoperative Recovery, Low Back Pain, Rehabilitation
- Trial name
- AQUA-SPINE (NCT07596238)
- Testing
- Swimming-Based Rehabilitation, Standard Rehabilitation
- Where
- Vietnam
- Volunteers
- 124 people
- Sponsor
- Tra Vinh General Hospital
Thoracolumbar Burst Fracture
Comparison of Posterior Fixation Alone and Combined With Articular Process Fusion in Thoracolumbar Burst Fractures
Nearly 90% of all spinal fractures occur in the thoracolumbar region, and burst fractures are composed of 15% of such injuries. But the treatment of thoracolumbar fractures remains controversial.
- Trial name
- NCT01864785
- Testing
- Fixation Combined With Fusion, Fixation Alone
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Jinling Hospital, China
Degenerative Spinal Conditions
A Pre-market Study to Evaluate b.Bone for Posterolateral Fusion (b.Spine Clinical Trial).
Prospective, open-label, single-arm clinical investigation. The purpose of this clinical investigation is to evaluate the bone substitute b.Bone in posterolateral fusion treatment of degenerative thoracolumbar, lumbar or…
- Trial name
- NCT05906394
- Testing
- Posterolateral Fusion
- Where
- 2 sites in Germany, Italy
- Volunteers
- 16 people
- Sponsor
- GreenBone Ortho S.p.A.
Spinal Fusion
BMAC & Allograft vs BMP-2
The aim of this investigation is to compare the use of bone marrow aspirate concentrate (BMAC) and allograft versus recombinant human bone morphogenetic protein-2 (BMP) versus the gold standard fusion in subjects undergoing…
- Trial name
- NCT02924571
- Testing
- Bone Marrow Aspirate Concentrate (BMAC) + Allograft, Recombinant Human Bone Morphogenetic Protein-2 (BMP), Autograft
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- NYU Langone Health
Postoperative Pain, Spinal Fusion Surgery
TLIP Block Versus Retrolaminar Block on Quality of Recovery After Posterior Lumbar Spine Fusion Surgery
This prospective randomized controlled study aims to compare the effects of ultrasound-guided thoracolumbar interfascial plane (TLIP) block versus retrolaminar block on postoperative quality of recovery in patients undergoing…
- Conditions
- Postoperative Pain, Spinal Fusion Surgery, Degenerative Lumbar Spine Diseases
- Trial name
- TLIP-RLB-QoR (NCT07609212)
- Testing
- Thoracolumbar interfascial plane block, Retrolaminar block
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Assiut University
Anesthesia
Comparison of Total Intravenous Anesthesia Methods in Spinal Surgery (TIVA)
This study aims to compare the effects of the classical Total Intravenous Anesthesia (TIVA) method and multimodal anesthesia protocols created by adding lidocaine and ketamine infusions on postoperative pain management, opioid…
- Trial name
- TIVA (NCT06781177)
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital