Clinical trials: Thoracoscopic Lobectomy
Thoracoscopic Lobectomy
Phase Ⅱ Study of Intercostal Nerve Block With HR18034 for Postsurgical Pain Management
Phase Ⅱ, randomized, double-blind, comparator-controlled study to evaluate the efficacy, safety and pharmacokinetics of single injection intercostal nerve block with HR18034 for postoperative pain management compared with…
- Trial name
- NCT05744674
- Testing
- HR18034, Ropivacaine Hydrochloride Injection
- Where
- China
- Volunteers
- 96 people
- Sponsor
- Shanghai Hengrui Pharmaceutical Co., Ltd.
Non-small Cell Lung Cancer
Assisted-VATS Sleeve Lobectomy for Non-small Cell Lung Cancer
The purpose of this study is to examine the feasibility of assisted-VATS (video-assisted thoracoscopic surgery) sleeve lobectomy for non-small cell lung cancer for non-small cell lung cancer.
- Trial name
- VATS (NCT00997724)
- Testing
- a-VATS
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Lung, Lung Adenocarcinoma
Reinforced and Non-Reinforced Staple Lines in Fissureless Lobectomy
Prolonged Air Leak (PAL) is a common and serious problem after lung surgery. It can lead to worse patient outcomes, longer hospital stays, and higher costs.
- Conditions
- Lung, Lung Adenocarcinoma, Lung Adenosquamous Carcinoma, Lung Cancer, Non-Small Cell
- Trial name
- NCT06602661
- Testing
- Fissureless Lobectomy with Reinforced Staple Lines, Fissureless Lobectomy with Non-Reinforced Staple Lines
- Where
- Canada
- Volunteers
- 65 people
- Sponsor
- Surrey Thoracic Surgery Group
Postoperative Analgesia
Effect of Paracetamol and Mannitol Injection on Postoperative Analgesia in Patients With Thoracoscopic Lobectomy
This study thoroughly evaluates the efficacy of acetaminophen mannitol injection for postoperative analgesia in patients undergoing thoracoscopic lobectomy, by comparing it with a control group.
- Trial name
- NCT06304181
- Testing
- Paracetamol and Mannitol Injection, Parecoxib
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Hemodynamics, Postoperative Recovery
Effect of Ciprofol Infusion for Induction and Maintenance on Hemodynamics and Postoperative Recovery
To study the Effect of Ciprofol Infusion for Induction and Maintenance of anesthesia on Hemodynamics and Postoperative Recovery in Patients Undergoing Thoracoscopic Lobectomy:a randomized, controlled trial.
- Conditions
- Hemodynamics, Postoperative Recovery, Anesthesia
- Trial name
- NCT05664386
- Testing
- propofol, ciprofol
- Where
- China
- Volunteers
- 126 people
- Sponsor
- Xiumei Song
Lung Cancer, Pain, Postoperative
Pain Control After VATS Anatomical Pulmonary Resections
In patients undergoing minimally invasive thoracoscopic surgery (video-assisted thoracoscopic surgery, or VATS), moderate to severe post-operative pain may often be experienced.
- Conditions
- Lung Cancer, Pain, Postoperative, Thoracic Neoplasms
- Trial name
- NCT05993273
- Testing
- Epidural, ESP block, Cryoanalgesia
- Where
- Italy
- Volunteers
- 75 people
- Sponsor
- University Hospital Padova
Non-small Cell Lung Cancer, Thoracic Surgery
Robotic Lobectomy vs. Thoracoscopic Lobectomy for Early Stage Lung Cancer: RCT
During video-assisted thoracoscopic lobectomy (VATS), the surgeon inserts a small camera attached to a thoracoscope that puts the image onto a video screen.
- Trial name
- NCT02617186
- Testing
- Video-assisted thoracoscopic surgery, Robotic thoracic surgery
- Where
- Canada
- Volunteers
- 446 people
- Sponsor
- St. Joseph's Healthcare Hamilton
Post Operative Pain, Thoracic Cancer
Thoracic Paravertebral Block With Methylene Blue Visual Confirmation for Postoperative Pain After VATS Lobectomy
The goal of this study is to compare the efficacy in controlling postoperative pain of paravertebral block (PVB) with methylene blue visual confirmation and thoracic epidural anesthesia (TEA).
- Trial name
- NCT05812521
- Testing
- Paravertebral block with methylene blue, Thoracic Epidural Anesthesia
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- University of Campania Luigi Vanvitelli
Minimally Invasive Surgical Procedures, VATS
Prolonged Hospital Stay After Thoracoscopic Anatomical Lung Resections
In this study, the reasons for prolonged hospital stay after thoracoscopic (video- or robot-assisted) anatomical lung resections are investigated.
- Conditions
- Minimally Invasive Surgical Procedures, VATS, RATS Surgery, Pulmonary Lobectomy
- Trial name
- PROTRACT (NCT06638645)
- Testing
- VATS/RATS anatomical lung resection
- Where
- 2 sites in Belgium
- Volunteers
- 140 people
- Sponsor
- University Hospital, Ghent
Lung Cancer
Thoracoscopic Lobectomy Using Nonintubated Anesthesia Versus Intubated General Anesthesia for Lung Cancer Patients
The purpose of this study is to study the safety and results of thoracoscopic lobectomy using non-intubated thoracic epidural anesthesia versus intubated general anesthesia for lung cancer patients.
- Trial name
- NCT01533233
- Testing
- thoracoscopic lobectomy and mediastinal lymph node dissection
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital
Ipsilateral Shoulder Pain, Lung Neoplasms
Effect of Modified Arm Positioning on Shoulder Pain After Thoracoscopic Lobectomy
This study is a prospective randomized controlled trial aiming to reduce shoulder pain after lung surgery. Shoulder pain on the surgical side is common after video-assisted thoracoscopic lobectomy, affecting about 20%-58% of…
- Trial name
- NCT07746323
- Testing
- Modified Double-Arm Wrap Positioning, Traditional Arm-Board Position
- Where
- China
- Volunteers
- 270 people
- Sponsor
- Chengdu Jinjiang Maternity and Child Health Hospital
Video-assisted Thoracoscopic Surgery, Inflammatory Reaction
Comparison of Inflammatory Cytokine Levels Between Single-port and Three-port Thoracoscopic Lobectomy in the Treatment of Non-small Cell Lung Cancersurgery on Perioperative Clinical Indexes、Inflammatory Reaction and Quality of Life Scores of Patients With Non-small Cell Lung Cancer
Many recent studies have shown that surgical trauma will result in an immunosuppressive state. Combined with the effect of surgical stress, it will often lead to metabolic changes, systemic inflammatory response, and other…
- Conditions
- Video-assisted Thoracoscopic Surgery, Inflammatory Reaction, Life Scores
- Trial name
- NCT05070026
- Testing
- uni-portal VATS group, three port VATS group
- Where
- China
- Volunteers
- 68 people
- Sponsor
- Shengjing Hospital
Non-small Cell Lung Cancer
Suction on Post-Operative Chest Tubes
The level of suction on post-operative chest tubes after video-assisted thoracoscopic surgery (VATS) lobectomy for lung cancer has previously shown to affect duration of drainage.
- Trial name
- SPOCT (NCT02911259)
- Testing
- Suction is set to -2 cmH2O, Suction is set to -10 cmH2O
- Where
- Denmark
- Volunteers
- 230 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Oxycodone, Thoracoscopic Lobectomy
Sequential Method Determination of Oxycodone for Thoracoscope Surgery Median Effective Dose of Acute Pain Treatment
The goal of this clinical trial is to measure the median effective dose of oxycodone for the treatment of acute pain after thoracoscopic lobectomy.
- Conditions
- Oxycodone, Thoracoscopic Lobectomy, Acute Postoperative Pain
- Trial name
- NCT06534801
- Testing
- Oxycodone will be administered intravenously in the group 1
- Volunteers
- 60 people
- Sponsor
- Jianbo Wu
Lung Cancer
Treatment of Early Stage Lung Cancer by VATS Versus OPEN Lobectomy
In patients with early stage lung cancer surgical lobectomy is the treatment of choice. A resection by Video-assisted Thoracic Surgery (VATS) is probably superior to an open procedure by thoracotomy for patients with early stage…
- Trial name
- SCOPE (NCT01933828)
- Testing
- OPEN lobectomy, VATS lobectomy, ROBOT-assisted lobectomy
- Where
- Netherlands
- Volunteers
- 176 people
- Sponsor
- Radboud University Medical Center
Postoperative Chronic Cough
Effect of Disconnecting Pulmonary Vagus Nerve Branch on Chronic Cough After Unilateral Thoracoscopic Lobectomy
The purpose of this study was to determine whether disconnecting pulmonary vagus nerve branch can abatement chronic cough in patients undergoing unilateral thoracoscopic lobectomy,compared with preserving pulmonary vagus nerve…
- Trial name
- NCT04247997
- Testing
- disconnect pulmonary vague nerve branches
- Where
- China
- Volunteers
- 116 people
- Sponsor
- Han Yuan
Pulmonary Neoplasm
Robot-assisted vs VATS Lobectomy for NSCLC
Robot-assisted thoracoscopic surgery (RATS) was widely used in thoracic surgery, the surgical safety and feasibility of RATS lobectomy for NSCLC has been confirmed.
- Trial name
- RVlob (NCT03134534)
- Testing
- VATS lobectomy, RATS lobectomy
- Where
- China
- Volunteers
- 320 people
- Sponsor
- Ruijin Hospital
Lung Cancer
Modified Video-assisted Thoracoscopic Surgery (VATS) Lobectomy for Early-stage Non-small Cell Lung Cancer (NSCLC)
The purpose of this study is to modify the surgical technique of VATS (video-assisted thoracoscopic surgery) lobectomy for early-stage non-small cell lung cancer.
- Trial name
- NCT01337037
- Testing
- VATS lobectomy using modified equipments, VATS lobectomy using less staples, Standard VATS lobectomy
- Where
- 14 sites in China
- Volunteers
- 1,000 people
- Sponsor
- Peking University People's Hospital
Video Assisted Thoracoscopic Surgery, Thoracic Surgery
Diaphragmatic Thickness and Functional Exercise Capacity in Lobectomy Surgeries With Thoracotomy and VATS
The most commonly treatment for early stage non-small cell lung cancer (NSCLC) is lobectomy. Different surgical interventions during lobectomy are thought to have different effects on respiratory functions and exercise…
- Conditions
- Video Assisted Thoracoscopic Surgery, Thoracic Surgery, Respiratory Muscles
- Trial name
- NCT05669196
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Hacettepe University
Postoperative Pain
Analgesic Efficacy of an Opioid-free Postoperative Pain Management Strategy Versus a Conventional Opioid-based Strategy Following Video-assisted Thoracoscopic Lobectomy
Investigators have designed a randomized controlled trial. Utilizing an open-label, randomized, controlled study methodology, this trial aims to explore a opioid-free, safe, and effective analgesic approach for thoracic surgery.
- Trial name
- NCT06570538
- Testing
- Ropivacaine, Sufentanil
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Affiliated Cancer Hospital & Institute of Guangzhou Medical University