Clinical trials: Thoracoscopy
Covid19, Global Impact
Global Impact of COVID-19 on Pulmonology Special Units
The COVID-19 pandemic is having a profound impact on the world. As of May 18, 2020, there were 4,889,287 confirmed cases and 322,683 deaths globally.
- Conditions
- Covid19, Global Impact, Pulmonology
- Trial name
- NCT04554251
- Testing
- Survey
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
Thoracoscopy, Pleural Effusion Disorder
Visual Assessment vs ROSE in Diagnosing Pleural Effusion Using Medical Thoracoscopy
The goal of this observational diagnostic study is to find how well two evaluation methods used during medical thoracoscopy can help identify whether pleural disease is malignant or benign.
- Trial name
- NCT07286045
- Testing
- Medical thoracoscopy
- Where
- Egypt
- Volunteers
- 33 people
- Sponsor
- Ain Shams University
Dexamethasone Adverse Reaction, Postoperative Pain
Role of Dexamethasone in Multimodal Analgesia for Postoperative Pain in Thoracic Surgery
The aim of the study is to evaluate the analgesic properties of dexamethasone and to quantify the possible associated postoperative complications, such as wound infections and hyperglycaemia, in patients who underwent lobectomy…
- Conditions
- Dexamethasone Adverse Reaction, Postoperative Pain, Postoperative Thoracic Procedure Complication, Analgesia
- Trial name
- NCT04325984
- Testing
- Dexamethasone
- Where
- Italy
- Volunteers
- 62 people
- Sponsor
- University of Trieste
Video-assisted Thoracoscopic Surgery, Lung Cancer
Intraoperative Conversion During Video-assisted Thoracoscopy Resection for Lung Cancer Does Not Alter Survival
Anatomical resection with systematic lymph-node dissection is currently the standard of care for the treatment of early stage non-small cell lung cancer.
- Conditions
- Video-assisted Thoracoscopic Surgery, Lung Cancer, Lobectomy, Survival
- Trial name
- ICVATR (NCT04663191)
- Testing
- anatomical resection
- Where
- France
- Volunteers
- 843 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Pain, Postoperative, Pharmacokinetics
Liposomal Bupivacaine Versus Plain Bupivacaine After Intercostal Injections For Pain Management After Thoracoscopy
The purpose of this study is to assess pharmacokinetics of liposomal bupivacaine (Exparel) after multilevel intercostal injections of this local anesthetic for pain control during and after thoracoscopic surgeries.
- Trial name
- NCT03737292
- Testing
- Exparel, Bupivacaine
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Milton S. Hershey Medical Center
Lung Neoplasms
Rational Approach to a Unilateral Pleural Effusion2
Recurrent unilateral, non-infectious pleural exudate is suspicious for primary or secondary pleural malignancy. Both conditions are associated with 5-year survival of 10%.
- Trial name
- REPEAT (NCT02834455)
- Testing
- Contrast-enhanced CT, PET-CT
- Where
- Denmark
- Volunteers
- 200 people
- Sponsor
- Simon Reuter
Lung Cancer
Predicting Symptom Trajectories After Thoracoscopic Lung Cancer Surgery Using an Interpretable Machine Learning Model
Patients suffer from a variety of symptoms after thoracoscopic surgery. However, there is a lack of validated predictive tools to identify potentially high-risk patients.
- Trial name
- NCT06771947
- Where
- China
- Volunteers
- 1,500 people
- Sponsor
- Guangdong Provincial People's Hospital
Thymoma
Robot-assisted vs VATS for Thymoma
The aim of this study is to explore the advantages of robot-assisted thymectomy in long-term survival benefits and short-term clinical efficacy compared with video-assisted thoracoscopic thymectomy based on a multi-center…
- Trial name
- NCT06029621
- Testing
- RATS for Thymectomy, VATS for Thymectomy
- Where
- 2 sites in China
- Volunteers
- 304 people
- Sponsor
- Shanghai Pulmonary Hospital, Shanghai, China
Lung Cancer
Sleep Disorders in Patients With Suspected Lung Cancer Before and After Thoracic Surgery
The main aim of this study is to prospectively evaluate the occurrence of sleep disorders in patients undergoing thoracic surgery due to the preliminary diagnosis of lung cancer.
- Trial name
- NCT04759651
- Testing
- Functional Outcome of Sleep Questionnaire Turkish version (FOSQ-TR), Epworth Sleepiness Scale (ESS), Berlin Questionnaire
- Where
- Turkey (Türkiye)
- Volunteers
- 1,200 people
- Sponsor
- Koç University
Medical Thoracoscopy
Surgical Site Preparation in Subjects Undergoing Medical Thoracoscopy
Medical thoracoscopy is the preferred procedure for performing pleural biopsy in patients with pleural effusions that remain undiagnosed after pleural fluid analysis.
- Trial name
- CAPTAIN (NCT05430308)
- Testing
- Chlorhexidine scrub, Povidone-iodine
- Where
- 2 sites in India
- Volunteers
- 100 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Pleural Effusion Disorder
Ultrasounic Elastography-guided Pleural Biopsy Followed by As-needed Medical Thoracoscopic Pleural Biopsy Versus Immediate Medical Thoracoscopic Pleural Biopsy for the Diagnosis of Pleural Effusion
Brief Summary The goal of this clinical trial is to determine whether an initial diagnostic approach using ultrasound elastography-guided pleural biopsy (UEPB) is non-inferior to immediate medical thoracoscopic pleural biopsy in…
- Trial name
- NCT07419620
- Testing
- Ultrasoinc elastography-guided pleural biopsy followed by as-needed medical thoracoscopic pleural biopsy, Semi-rigid thoracoscopic pleural biopsy
- Where
- China
- Volunteers
- 420 people
- Sponsor
- China-Japan Friendship Hospital
Lung, Lung Adenocarcinoma
Reinforced and Non-Reinforced Staple Lines in Fissureless Lobectomy
Prolonged Air Leak (PAL) is a common and serious problem after lung surgery. It can lead to worse patient outcomes, longer hospital stays, and higher costs.
- Conditions
- Lung, Lung Adenocarcinoma, Lung Adenosquamous Carcinoma, Lung Cancer, Non-Small Cell
- Trial name
- NCT06602661
- Testing
- Fissureless Lobectomy with Reinforced Staple Lines, Fissureless Lobectomy with Non-Reinforced Staple Lines
- Where
- Canada
- Volunteers
- 65 people
- Sponsor
- Surrey Thoracic Surgery Group
Pleurisy With Effusion
A Trial of Rigid Versus Semirigid Thoracoscopy in the Evaluation of Exudative Pleural Effusions
Rigid thoracoscopy is an established procedure for the performance of pleural biopsies for undiagnosed pleural effusions. The semirigid thoracoscope is a relatively new instrument designed for the same purpose which is claimed to…
- Trial name
- RISE (NCT01726556)
- Testing
- Rigid thoracoscope (Richard Wolf GmbH, Knittlingen, Germany), Semirigid thoracoscope (model LTF-160Y1, Olympus, Japan)
- Where
- India
- Volunteers
- 70 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Pleural Effusion, Malignant, Non-small Cell Carcinoma
Intrapleural Docetaxel Administration Using Medical Pleuroscopy in Malignant Effusion With Lung Cancer
In this trial, the effect of intrapleural docetaxel administration using medical pleuroscopywill be evaluated in Lung Cancer patient with malignant effusion.
- Trial name
- NCT03394105
- Testing
- intrapleural docetaxel administration
- Where
- South Korea
- Volunteers
- 4 people
- Sponsor
- Asan Medical Center
Esophageal Atresia With Tracheo-esophageal Fistula, Congenital Diaphragmatic Hernia
Open or Keyhole Surgery Through the Chest for Newborn Babies: Effect on Blood Gases
This is a pilot randomised controlled trial comparing open versus thoracoscopic surgery for repair of oesophageal atresia with tracheo-oesophageal fistula or congenital diaphragmatic hernia in neonates.
- Trial name
- CO2 (NCT01467245)
- Testing
- Hypercapnia during thoracoscopy, Open surgery
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Great Ormond Street Hospital for Children NHS Foundation Trust
Pleural Mesothelioma
From Presentation to Diagnosis: Patterns of Pleural Effusion
Pleural effusion is a common clinical condition characterized by the accumulation of excess fluid within the pleural space due to disruption of normal pleural fluid dynamics.
- Trial name
- NCT07449624
- Testing
- Pleural effusion pathology
- Where
- Egypt
- Volunteers
- 300 people
- Sponsor
- Mansoura University Hospital
Non Small Cell Lung Cancer
Dry Pleurodesis With Talcum and Afatinib is Used to Treat Patients With Non-Small Cell Lung Carcinoma
In non-small cell lung cancer and metastases in the pleural cavity, pathological effusion is formed. Currently, the most common and effective method of obliteration of the pleural cavity is pleurodesis with talcum powder.
- Trial name
- DPTA (NCT03827070)
- Testing
- Afatinib, Talcum powder
- Where
- Georgia
- Volunteers
- 12 people
- Sponsor
- Center Trials & Treatment Europe
Haemothorax, Empyema
VATS ( Video-Assisted Thoracoscopy) Compared to Reinsertion of a Thoracostomy Tube for Persistent Haemothorax
This is a prospective, randomized study comparing VATS( Video-Assisted Thoracoscopy ) to reinsertion of a Thoracostomy Tube in patients with retained haemothorax.
- Trial name
- NCT02014077
- Testing
- VATS ( Video-Assisted Thoracoscopy ), Thoracostomy Tube reinsertion
- Where
- South Africa
- Volunteers
- 62 people
- Sponsor
- University of Cape Town
Wedge Resection, Lobectomy by Video-thoracoscopies
Intraoperative Hypotension Predicted by Mean Arterial Pressure
During general anesthesia, intraoperative hypotension (IOH) is associated with increased morbidity and mortality. Mean arterial pressure (MAP) < 65mmHg is the most common definition of hypotension.
- Trial name
- HYPPOPOPAM (NCT05147012)
- Testing
- Data collected
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Hospices Civils de Lyon
Pneumothorax
A Prospective Randomised Study of Efficacy, Safety and Costs of Talc Pleurodesis Under Medical Thoracoscopy and Pleurodesis Under Video-assisted Thoracoscopy Surgery for Recurrent Primary Spontaneous Pneumothorax
Treatment of recurrent primary spontaneous pneumothorax remains controversial and many therapeutic options exist. The aim of this study is to compare pleural symphysis by talc poudrage during medical thoracoscopy and surgical…
- Trial name
- NCT00767962
- Testing
- talc pleurodesis under medical thoracoscopy, pleurodesis under video-assisted thoracoscopy surgery
- Where
- France
- Volunteers
- 62 people
- Sponsor
- Assistance Publique Hopitaux De Marseille