Clinical trials: Thoracotomy
Postoperative Pain
Comparison of Paravertebral Versus Epidural Block for Post-thoracotomy Pain Control
This is a randomized, assessor-blinded, non-inferiority clinical trial comparing continuous thoracic paravertebral block (BPV) versus continuous thoracic epidural block (BPD) for postoperative pain control in adult patients…
- Trial name
- NCT07763249
- Testing
- Continuous Thoracic Paravertebral Block, Continuous Thoracic Epidural Block
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Chronic Post-thoracotomy Pain, Acute Post-thoracotomy Pain
Intraoperative Cryoanalgesia for Extended Pain Management Following Thoracotomy
The ICE Study study will compare standard therapy (thoracic epidural) versus a novel approach (Cryoanalgesia combined with thoracic epidural) in subjects undergoing unilateral thoracotomy.
- Conditions
- Chronic Post-thoracotomy Pain, Acute Post-thoracotomy Pain, Post-thoracotomy Pain Syndrome
- Trial name
- ICE (NCT03538340)
- Testing
- Thoracic Epidural, Intercostal Cryoanalgesia
- Where
- United States
- Volunteers
- 138 people
- Sponsor
- University of Maryland, Baltimore
Ultrasound, Serratus Anterior Plane Block
Ultrasound Guided Serratus Anterior Plane Block Versus Thoracic Erector Spinae Plane Block for Post Operative Analgesia in Pediatrics Undergoing Thoracotomy
This study is designed to compare the post operative analgesic effect of serratus anterior plane block versus thoracic erector spinae plane block in pediatrics undergoing thoracotomy
- Conditions
- Ultrasound, Serratus Anterior Plane Block, Thoracic Erector Spinae Plane Block, Post Operative Analgesia
- Trial name
- NCT06862518
- Testing
- Control group, Serratus Anterior Plane Block (SAPB) group, Erector Spinae Plane Block (ESPB) group
- Where
- Egypt
- Volunteers
- 105 people
- Sponsor
- Tanta University
Diaphragmatic Plication, Diaphragmatic Paralysis
Short- and Long-term Effects of Robot-assisted Plication in Diaphragmatic Paralysis
Diaphragmatic paralysis may lead to severe symptoms such as breathlessness and reduced physical capacity. Diaphragmatic plication using Robotic-Assisted Thoracic Surgery (RATS) is a minimally invasive surgical technique developed…
- Conditions
- Diaphragmatic Plication, Diaphragmatic Paralysis, Diaphragmatic Eventration
- Trial name
- RAPIDLY (NCT06919185)
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Uppsala County Council, Sweden
Pain, Postoperative
Serratus Anterior Plane Block Versus Intercostal Block
Pain after thoracotomy is the most severe pain experienced by the patient. Good pain control after the operation provides comfortable respiration and reduces the development of chronic pain and complications.
- Trial name
- NCT03309267
- Testing
- Intercostal block, Serratus anterior plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Anesthesia
Serratus Anterior Plane Block Versus Erector Spinae Plane Block. for Thoracotomy in Pediatric Patients
This randomized controled trial is designed to compare efficacy and safty of serratus anterior plane block versus erector spinae plane block for thoracotomy in pediatric patients.
- Trial name
- NCT04933877
- Testing
- Fascial plane block
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Cairo University
Pain, Postoperative, Anesthesia
The Efficacy of Serratus Anterior Plane Block (ESAPB) for Thoracotomy: a Prospective Study
Thoracotomy is considered the most painful surgical procedure. Ultrasound-guided serratus anterior plane block (SAPB) is a relatively new truncal block method treating thoracotomy pain.
- Conditions
- Pain, Postoperative, Anesthesia, Thoracotomy
- Trial name
- NCT03839160
- Testing
- Serratus anterior plane block, Intravenous patient-controlled-analgesia morphine
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Shanghai Zhongshan Hospital
Thoracostomy Pain Management, Pain Management
The Clinical Impact of Serratus Anterior VS. Erector Spinae Plane Block on Pain Management of Tube Thoracostomy in Emergency Department Patients.
In the emergency department, tube thoracostomy is a common critical procedure to manage symptomatic pleural issues such as pneumothorax and pleural effusion.[1] This technique employed to remove air or fluid from the pleural…
- Conditions
- Thoracostomy Pain Management, Pain Management, Chest Tube Insertion
- Trial name
- NCT07823920
- Testing
- serratus anterior plane blocks, Erector Spinae Plane Block
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Assiut University
Thoracic Diseases
Erector Spinae Plane Block Versus Perioperative Intravenous Lidocaine for Thoracotomy
Thoracotomy surgery is the most painful of all surgical procedures. Inadequate postoperative pain control in these patients may cause serious morbidity related to pulmonary, cardiovascular and emotional systems.
- Trial name
- NCT04221880
- Testing
- Bupivacaine Hcl 0.25% Inj, Saline Solution for Block, Saline Solution intravenously
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ataturk University
Analgesia
Perioperative Thoracotomy Analgesia; Different Analgesic Modalities
the study aim is to compare the analgesic effect of thoracic epidural versus serratus plane block versus erector spinae block in thoracic surgeries
- Trial name
- NCT04264689
- Testing
- serratus anterior block, thoracic epidural, erector spinae block
- Where
- Egypt
- Volunteers
- 51 people
- Sponsor
- National Cancer Institute, Egypt
Thoracotomy
Different Approaches to Thoracic Paravertebral Block
Thoracic paravertebral block (TPB) in thoracic surgery is practiced since the development of minimally invasive surgery. Historically, thoracic epidural analgesia is done in open thoracic surgery.
- Trial name
- VAP BLOCK (NCT04579276)
- Testing
- Thoracic paravertebral block, thoracic epidural analgesia
- Where
- France
- Volunteers
- 180 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Post-operative Pain, Respiratory Depression
Dexmedetomidine for the Control of Post-Operative Pain in Thoracotomy Patients
The purpose of this study is to evaluate the safety, efficacy, hemodynamic and respiratory stability of a low-dose of dexmedetomidine infusion in post-operative surgical in-patients undergoing thoracic surgery after discharge…
- Trial name
- NCT00345384
- Testing
- Dexmedetomidine
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Baylor Research Institute
Postoperative Pain, Mitral Valve Disease
ESP vs ESP With PECS
Patients scheduled for minimally invasive mitral valve repair. Each patient will be treated with intravenous (i.v.) oxycodone - patient-controlled analgesia (PCA).
- Trial name
- NCT03592485
- Testing
- Erector Spinae Plane blockade, Pectoral Fascia block, Oxycodone
- Where
- Poland
- Volunteers
- 33 people
- Sponsor
- Medical University of Lublin
Thoracic Anesthesia, Thoracotomy
Opioid Consumption After Thoracotomy and Factors Affecting Postoperative Acute Pain
Thoracic surgery operations constitute a significant portion of surgical procedures performed in hospitals. In the United States, more than 50,000 thoracic surgical procedures are performed annually, and more than 80% of these…
- Conditions
- Thoracic Anesthesia, Thoracotomy, Opioid, Postoperative Pain Management
- Trial name
- NCT07329855
- Testing
- Opioid Analgesic, Pain Medicine
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Ankara Ataturk Sanatorium Training and Research Hospital
VATS, Kinesiophobia
Comparison of Early Postoperative Functional Capacity and Kinesiophobia in Patients Undergoing Thoracic Surgery Via Thoracotomy or VATS
This observational cross-sectional study aims to compare early postoperative functional capacity and kinesiophobia in patients undergoing thoracic surgery via thoracotomy or video-assisted thoracic surgery (VATS).
- Conditions
- VATS, Kinesiophobia, Thoracotomy, Thoracic Surgery
- Trial name
- NCT07647822
- Where
- Turkey (Türkiye)
- Volunteers
- 18 people
- Sponsor
- Hacettepe University
Thoracotomy
Ultrasound-guided Approach Combined With Pressure Measurement Technique to Thoracic Paravertebral Block
Posterolateral thoracotomies are among the most painful procedures of surgery and may cause severe postoperative chest pain and impaired respiratory performance.
- Trial name
- NCT03868917
- Testing
- thoracic paravertebral block using pressure measurement technique
- Where
- South Korea
- Volunteers
- 72 people
- Sponsor
- Yeungnam University College of Medicine
ATRIAL APPENDAGE CLOSURE for ATRIAL FIBRILLATION, Oral Anticoagulation
Standalone Thoracoscopic Left Atrial Appendage Closure Versus Medical Therapy in Atrial Fibrillation
Surgical left atrial appendage closure (LAAC) has been associated with reduced rates of stroke in patients with atrial fibrillation (AF) who have undergone cardiac surgery.
- Conditions
- ATRIAL APPENDAGE CLOSURE for ATRIAL FIBRILLATION, Oral Anticoagulation, Thoracotomy
- Trial name
- STELLA-AF (NCT07705282)
- Testing
- Video-assisted thoracoscopic closure of the left atrial appendage using a closure device and discontinuation of treatment if the patient is treated with OAC
- Where
- Sweden
- Volunteers
- 936 people
- Sponsor
- Region Skane
Postoperative Pain Management
Study in Adult Subjects Undergoing Posterolateral Thoracotomy
Primary Objective: To characterize the pharmacokinetic (PK) profile of EXPAREL when administered as a posterior intercostal nerve block. Secondary Objective: To assess the safety and tolerability of EXPAREL in this surgical model.
- Trial name
- NCT03428984
- Testing
- EXPAREL
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Pacira Pharmaceuticals, Inc
Pain Following Thoracotomy Surgery
Study of Exparel Versus Epidural for Pain Control After Thoracotomy
Unilateral intercostal nerve blocks provide pain control as effectively as a continuous thoracic epidural, and will a lower incidence of side effects.
- Trial name
- NCT02178553
- Testing
- Epidural, Intercostal Bupivicaine (Exparel)
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- Mayo Clinic
Thoracic Diseases
Comparison of Continuous Erector Spina Plane Block With Intercostal Block in Acute and Chronic Pain Control After Thoracotomy
Thoracotomy is associated with severe postoperative pain due to surgical incision, rib retraction or resection, and intercostal nerve damage.
- Trial name
- NCT04309630
- Testing
- intercostal block, erector spina plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Ankara University