Clinical trials: Thoughts of Self Harm
Suicidal Ideation, Suicide Attempt
A Randomized Controlled Trial of a Smartphone Delivered Treatment for Suicidal Thoughts and Behavior
This study aims to evaluate the acceptability, safety, and efficacy of a smartphone-delivered intervention called Therapeutic Evaluative Conditioning for Suicide (TEC-S) in reducing suicidal thoughts and behaviors (STB) among…
- Trial name
- NCT06686901
- Testing
- Smartphone-delivered Therapeutic Evaluative Conditioning for Suicide (TEC-S), Smartphone-delivered inactive Therapeutic Evaluative Conditioning
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Massachusetts General Hospital
Suicidal Ideation, Suicide Prevention
User Evaluation Think Life
This study aims to evaluate user experiences with the online self-help course Think Life, a suicide prevention intervention for individuals experiencing suicidal thoughts.
- Conditions
- Suicidal Ideation, Suicide Prevention, mHealth Intervention
- Trial name
- NCT07654127
- Testing
- Self-help course Think Life
- Where
- Belgium
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University Ghent
Substance Use Disorders, Depression
Study of a Transdiagnostic, Emotion-focused Group Intervention for Young Adults With Substance Use Disorders
The overall aim of this pilot study is to conduct a preliminary trial to evaluate the acceptability and feasibility of adding a transdiagnostic, emotion-focused group intervention (the Unified Protocol, UP) to treatment as usual…
- Conditions
- Substance Use Disorders, Depression, Anxiety, Emotional Disorder
- Trial name
- ARMS UP (NCT03315208)
- Testing
- Unified Protocol (UP), Treatment as Usual (TAU)
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Massachusetts General Hospital
Suicidal Behavior, Suicidal Ideation
Evaluation of an App for Young People With Suicidal Thoughts
There are currently very few evidence-based tools specifically designed to support children and adolescents experiencing suicidal thoughts.
- Conditions
- Suicidal Behavior, Suicidal Ideation, Coping Behavior
- Trial name
- NCT07165561
- Testing
- Smartphone App
- Where
- Belgium
- Volunteers
- 32 people
- Sponsor
- University Ghent
Suicide
Mobile Intervention for Suicidal Thoughts
One of the factors that contributes to suicide risk is what is known as a "suicidal belief system." This belief system is made up of several cognitions that been associated with suicide risk among military personnel.
- Trial name
- NCT06593379
- Testing
- Safety planning, Treatment as usual, MIST Intervention
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- VA Office of Research and Development
Interpersonal Trauma, Depression
The BEAR Program for Women With Trauma Who Have Suicidal Thoughts
The current study aims to test the feasibility of a new form of group therapy for women who have a history of interpersonal trauma and current suicidal ideation.
- Conditions
- Interpersonal Trauma, Depression, PTSD, Anxiety
- Trial name
- BEAR-SI (NCT07346638)
- Testing
- BEAR-SI
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Stanford University
Suicidal Ideation, Suicidal
Reward Sensitivity Digital Intervention for Suicide Risk
The goal of this clinical trial is to develop and test an app designed to reduce suicide risk and improve emotional well-being in adolescents.
- Conditions
- Suicidal Ideation, Suicidal, Suicidal Thoughts, Digital Health Intervention
- Trial name
- DIGIReward (NCT07661901)
- Testing
- Suicide prevention treatment
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Pennsylvania
Suicide, Suicide, Attempted
Pilot Study of Health System/Community Partnership for Enhanced Outreach to Prevent Suicide Attempts
The goal of this clinical trial is to test an enhanced outreach intervention (EOI) delivered by Samaritans of Boston (a community organization that provides support during mental health crises) for people after they leave an…
- Conditions
- Suicide, Suicide, Attempted, Suicidal Ideation
- Trial name
- NCT05825820
- Testing
- Enhanced Outreach Intervention (EOI) plus Care as Usual
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Massachusetts General Hospital
Suicidal Thoughts and Behaviors
Development of PRECISE: A Data Driven Personalized Suicide Prevention Intervention
Individuals at high-risk of suicide vary substantially from one another. Over time, risk factors for suicide may change within the same individual.
- Trial name
- NCT06809348
- Testing
- PRECISE
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of California, San Diego
Binge Drinking, Suicidal Ideation
Open Pilot Trial Evaluating an Avatar-Guided Intervention for Emerging Adults With Alcohol Use Problems and Suicide Risk
This study is an open pilot usability trial to test the 1) usability of a newly developed mobile health intervention to help manage suicidal ideation and alcohol use problems and 2) feasibility of research protocols with emerging…
- Trial name
- EA-Avatar (NCT06595862)
- Testing
- EA-Avatar
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- University of Massachusetts, Worcester
Suicide Prevention, Suicidal Ideation
Co-creation of Tools for Children and Adolescents with Suicidal Thoughts And/or Behaviour
Evidence shows that there are very few evidence-based tools or interventions specifically targeting suicidality in children and adolescents.
- Conditions
- Suicide Prevention, Suicidal Ideation, Suicidal Behaviors
- Trial name
- Co-crea K&J (NCT06776328)
- Testing
- Tools
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- University Ghent
Suicidal Ideation
The Impact of Routine Follow-up Contacts After a Pediatric ED Visit for Youth With Suicide Risk
The goal of this clinical trial is to learn if a social work led follow up program helps caregivers of youths with suicide risk access mental health resources. Primary aims include: 1.
- Trial name
- NCT06616701
- Testing
- Follow up call
- Where
- United States
- Volunteers
- 401 people
- Sponsor
- Johns Hopkins University
Suicidal Ideation, Suicide
The Impact of Ketamine on the Reward Circuitry of Suicidal Patients
Every 40 seconds, someone in the world dies by suicide. There is a lack of effective and safe antisuicidal agents for preventing suicide attempts.
- Trial name
- NCT02532153
- Testing
- Ketamine Hydrochloride
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
PTSD, Suicidal Thoughts and Behaviors
Cannabis, Neuroinflammation, and Suicidal Ideation: A Supplemental Brain Imaging Study
This study will be the first to use brain imaging to explore how cannabis affects the brain and inflammation in U.S. military veterans with PTSD.
- Conditions
- PTSD, Suicidal Thoughts and Behaviors, PTSD Symptoms, Depressive Symptoms
- Trial name
- CNS (NCT07222306)
- Testing
- 1-(2-[+F]fluoroethyl)-L-tryptophan
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Wayne State University
Suicide Attempt, Suicide Ideation
A One-Arm Open Trial of a Smartphone Delivered Treatment for Suicidal Thoughts and Behavior
This study aims to evaluate the acceptability, safety, and preliminary efficacy of a smartphone-delivered intervention called Therapeutic Evaluative Conditioning for Suicide (TEC-S) in reducing suicidal thoughts and behaviors…
- Trial name
- NCT06967545
- Testing
- Smartphone-delivered Therapeutic Evaluative Conditioning for Suicide (TEC-S)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Massachusetts General Hospital
Suicide, Suicide, Attempted
A Health System/Community Partnership for Enhanced Outreach to Prevent Suicide Attempts
The goal of this study is to test an enhanced outreach intervention (EOI) delivered by Samaritans of Boston (a community organization that provides support during mental health crises) for people after they leave an emergency…
- Conditions
- Suicide, Suicide, Attempted, Suicidal Ideation
- Trial name
- NCT05837026
- Testing
- Enhanced Outreach Intervention (EOI) plus Care as Usual (CAU), Care as Usual (CAU)
- Volunteers
- 300 people
- Sponsor
- Massachusetts General Hospital
Suicide Prevention, Informal Caregivers
Needs Assessment Among Carers of Someone With Suicidal Thoughts
With this study the investigators would like to gain insight into the experienced needs carers of individuals with suicidal thoughts, who attempted suicide or who died by suicide.
- Trial name
- NCT06611956
- Testing
- No intervention (observational study)
- Where
- Belgium
- Volunteers
- 2,255 people
- Sponsor
- University Ghent
Suicidal Ideation, Suicide Attempt
Efficacy, Effectiveness, and Implementation of Jaspr Health in Emergency Department- Part B
This Study will evaluate the implementation of a multi-component suicide prevention technology (Jaspr Health) that facilitates delivery of suicided-related evidence-based practices (EBPs) while replacing wasted waiting time with…
- Conditions
- Suicidal Ideation, Suicide Attempt, Self Harm
- Trial name
- Jaspr-PartB (NCT06311591)
- Testing
- Jaspr App
- Where
- 4 sites in United States
- Volunteers
- 27,908 people
- Sponsor
- University of Massachusetts, Worcester
Suicidal Thoughts and Behaviors, Social Isolation
Qnnections: Refinement and Pilot Trial of a Suicide Prevention Intervention to Increase Social Connection
Despite the high risk of suicide among LGBTQ+ Veterans, there is currently no suicide-focused intervention for this population. This study will refine and pilot Qnnections, a novel group-based suicide prevention intervention that…
- Trial name
- Qnnections (NCT06803329)
- Testing
- Qnnections, Enhanced Usual Care
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- VA Office of Research and Development
Suicidal Ideation, Depression
Gamified VR Sports for Elderly Suicidal Ideation
Detailed Description: This quasi-experimental study investigates the effectiveness of a gamified sports exercise intervention delivered through virtual reality (VR) to improve mental health and life expectancy in elderly…
- Conditions
- Suicidal Ideation, Depression, Mental Health Issue
- Trial name
- VR-LIFE-SI (NCT06856083)
- Testing
- Gamified Virtual Reality Sports Exercise Program, Traditional Sports Exercise Program for Elderly Individuals with Suicidal Thoughts
- Where
- Iran
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Islamic Azad University, Sanandaj