Clinical trials: Thromboembolic Disease
Pulmonary Embolism, Thromboembolism
Nadroparin for the Initial Treatment of Pulmonary Thromboembolism
Low-molecular-weight heparin (LWMH) appears to be at least as effective and safe as standard, unfractionated heparin (UFH)for the treatment of patients with deep vein thrombosis(DVT) and may also be so in patients with pulmonary…
- Conditions
- Pulmonary Embolism, Thromboembolism, Vascular Diseases, Thrombosis
- Trial name
- NATSPUTE (NCT00796692)
- Testing
- Nadroparin, Unfractionated heparin(UFH)
- Where
- 39 sites in China
- Volunteers
- 274 people
- Sponsor
- Beijing Chao Yang Hospital
Venous Thromboembolism, Pelvic Surgery
Venous Thrombo-embolic Complication prévention in Pelvic Surgery
Pelvic fracture surgery are very high thrombotic risk surgery with about 10% to 50% venous thrombo embolic complications and 0.5% to 10% of pulmonary embolism. The ST JOSEPH's Hospital have almost 60 cases per year .
- Trial name
- NCT03535428
- Testing
- VENOUS exploration
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Pelvic Fractures, Acetabular Fractures
Incidence of Venous Thromboembolism in Patients With Pelvic and Acetabular Fractures (PAF)
The goal of this observational study is to investigate the incidence of venous thromboembolism (VTE) in patients with pelvic and acetabular fractures (PAF).
- Conditions
- Pelvic Fractures, Acetabular Fractures, Pelvic Trauma, Venous Thromboembolic Event
- Trial name
- PAF-VTE (NCT07165587)
- Testing
- Bilateral duplex ultrasonography
- Where
- Germany
- Volunteers
- 81 people
- Sponsor
- Department of Trauma and Reconstructive Surgery at Eberhard Karls University Tuebingen, BG Klinik Tu
Cancer, Venous Thromboembolism
Direct Oral Anticoagulants (DOACs) Versus LMWH +/- Warfarin for VTE in Cancer
The overarching objective of the study is to determine the effectiveness of LMWH/ warfarin vs. DOAC anticoagulation for preventing recurrent VTE in cancer patients.
- Conditions
- Cancer, Venous Thromboembolism, Deep Vein Thrombosis (DVT), Pulmonary Embolism (PE)
- Trial name
- CANVAS (NCT02744092)
- Testing
- Rivaroxaban, Apixaban, Edoxaban
- Where
- 151 sites in United States
- Volunteers
- 811 people
- Sponsor
- Alliance Foundation Trials, LLC.
Lung Cancer
Coagulation Profile in Patients Undergoing Video Assisted Thorascopic Surgery (VATS) for Lung Cancer
The purpose of the study is: To estimate patients with lung cancers who will undergo surgery total haemostatic / thrombotic capacity pre, per-and postoperatively.
- Trial name
- COPPVATS (NCT01741506)
- Testing
- Dalteparin (Fragmin®)
- Where
- 3 sites in Denmark
- Volunteers
- 116 people
- Sponsor
- Thomas Decker Christensen
Venous Thromboembolism
Postpartum Heparin Against Venous Thromboembolism: a Pilot Randomized Controlled Trial
In previous attemps to answer the question of risk-benefit of postpartum thromboprophylaxis, researchers were faced with low recruitement rates.
- Trial name
- PP-HEP (NCT05878899)
- Testing
- Enoxaparin
- Where
- Switzerland
- Volunteers
- 77 people
- Sponsor
- University Hospital, Geneva
Venous Thromboembolism
Abdominal Surgery Study Of GSK576428 (Fondaparinux Sodium)In Japanese Patients
This study is phase 3 study for prevention of VTE in patients with abdominal surgery.
- Trial name
- NCT00333021
- Testing
- Fondaparinux sodium, GSK576428
- Where
- 18 sites in Japan
- Volunteers
- 127 people
- Sponsor
- GlaxoSmithKline
Venous Thromboembolism, Liver Transplantation
Risk Factors and a nOmogram of Venous thromboEmbolism in Patients After liveR Transplantation(ROVER Study)
Liver transplantation is currently an effective treatment for end-stage liver disease. The high incidence of thrombotic related complications in the early postoperative period after orthotopic liver transplantation(OLT) has been…
- Trial name
- NCT05209048
- Where
- China
- Volunteers
- 356 people
- Sponsor
- Beijing Tsinghua Chang Gung Hospital
Advanced Gastric Cancer
Venous Thromboembolism in Advanced Gastric Cancer Patients
Venous thromboembolism (VTE), which includes pulmonary embolism (PE) and deep vein thrombosis (DVT), is a common complication and leading cause of death in cancer patients.
- Trial name
- NCT01047618
- Where
- South Korea
- Volunteers
- 259 people
- Sponsor
- Asan Medical Center
Venous Thromboembolic Disease
Value of D-dimer Combined With Other Thrombus Molecular Markers in Risk Assessment of VTE in Hospitalized Patients
The occurrence of VTE in hospital is an important cause of unexpected death of inpatients, and has become a serious problem faced by hospital managers and clinical medical staff.Under the target of "Improving the Standard…
- Trial name
- NCT05515549
- Testing
- Venous blood was collected from patients under fasting state to detect the level of thrombus molecular markers
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Qianfoshan Hospital
Pulmonary Thromboembolisms
Pulmonary Thromboembolism in Cancer Patients: Early Rule-out From the Emergency Department
Pulmonary thromboembolism is a frequent complication of cancer; in some cases, it is diagnosed occasionally during diagnostic examinations as part of the regular follow-up of the disease.
- Trial name
- NCT06761144
- Where
- Italy
- Volunteers
- 500 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Anorexia Nervosa, Thrombosis
Thromboembolism in Anorexia Nervosa
BACKGROUND: Sudden death due to thromboembolic (TE) events in patients with anorexia nervosa (AN) is well known. However, the incidence of TE events and the hemostatic balance in patients with AN are sparsely investigated.
- Conditions
- Anorexia Nervosa, Thrombosis, Thromboembolism
- Trial name
- TEAN (NCT05575466)
- Testing
- Blood samples, Questionnaires
- Where
- 5 sites in Denmark, Sweden
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Venous Thromboembolism
Fragmin for the Treatment of Acute VTE in Pediatric Cancer Patients
Three month treatment of acute VTE with Fragmin in pediatric cancer patients
- Trial name
- NCT00952380
- Testing
- dalteparin
- Where
- 26 sites in United States, Norway and 3 more
- Volunteers
- 38 people
- Sponsor
- Pfizer
Venous Thromboembolism (VTE), Post Partum Women
Prevention of Postpartum Venous Thromboembolism in Women at Intermediate Risk
Venous thromboembolism (VTE) is currently the second cause of death in women of reproductive age worldwide. The incidence of VTE during pregnancy is 1.2 to 1.4/1000 women, half of VTE occurring during postpartum and as PE in…
- Trial name
- MUM-VTE (NCT06845423)
- Testing
- Low molecular weight heparin
- Where
- 18 sites in France
- Volunteers
- 2,400 people
- Sponsor
- University Hospital, Brest
Spinal Cord Injuries, Thromboembolism
Absorption of Rivaroxaban in Patients With Cervical Spinal Cord Injury
The primary objective of this study is to investigate the pharmacokinetic and -dynamic properties of rivaroxaban after oral administration in cervical spinal cord injury (SCI) individuals.
- Trial name
- rivaroxaban (NCT02970773)
- Testing
- Rivaroxaban Oral Tablet
- Where
- Switzerland
- Volunteers
- healthy volunteers welcome
- Sponsor
- Swiss Paraplegic Research, Nottwil
Venous Thromboembolism (VTE), Acute Myocardial Infarction With ST Segment Elevation
Heat Shock Protein 47 in Thrombosis
The goal of this observational study is to learn if the novel biomarker Heat shock protein 47 (HSP47) can be used as a prognostic marker for vascular disease in people with acute venous thromboembolism (VTE), myocardial…
- Conditions
- Venous Thromboembolism (VTE), Acute Myocardial Infarction With ST Segment Elevation, Stroke (in Patients With Atrial Fibrillation)
- Trial name
- NCT06731673
- Where
- 2 sites in Denmark, Germany
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Pulmonary Embolism, Chronic Thromboembolic Pulmonary Hypertension
Chinese PE Multimodality Imaging Artificial Intelligence Study
The CHinese pulmOnary Embolism Multimodality Imaging-artifiCial intelligencE Study (CHOICE) is a prospective observational multi-center study that will collect imaging text data and raw data of patients with pulmonary embolism…
- Conditions
- Pulmonary Embolism, Chronic Thromboembolic Pulmonary Hypertension, Chronic Thromboembolic Pulmonary Disease
- Trial name
- NCT06526468
- Testing
- Artificial Intelligence
- Where
- China
- Volunteers
- 1,500 people
- Sponsor
- China-Japan Friendship Hospital
Glioblastoma, Astrocytoma
Venous Thromboembolism Prevention in Outpatients With Glioma
This is an open label study of apixaban for venous thromboembolism prevention in patients with newly diagnosed grade 4 glioma.
- Conditions
- Glioblastoma, Astrocytoma, Venous Thromboembolism
- Trial name
- VTE-POG (NCT05683808)
- Testing
- Apixaban
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Vermont Medical Center
Glioma, Malignant
Efficacy and Safety of Rivaroxaban in the Prevention of Venous Thromboembolism in Glioma Patients
Glioma is a common brain tumor with a high risk of venous thromboembolism during treatment, especially in the months after surgery.
- Trial name
- NCT06196918
- Testing
- Rivaroxaban 10 MG
- Where
- 8 sites in China
- Volunteers
- 320 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Hematoma
Strategy of Continued Versus Interrupted Novel Oral Anti-coagulant at Time of Device Surgery in Patients With Moderate to High Risk of Arterial Thromboembolic Events
The purpose of this study is to determine the best strategy to manage novel oral anti-coagulants (NOACs) at the time of pacemaker or defibrillator surgery.
- Trial name
- BRUISECONTROL2 (NCT01675076)
- Testing
- Dabigatran, Rivaroxaban, Apixaban
- Where
- 15 sites in Canada, Israel
- Volunteers
- 663 people
- Sponsor
- Ottawa Heart Institute Research Corporation
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