Clinical trials: Thromboembolic Disease
Renal Insufficiency, Chronic, Deep Venous Thrombosis, Protection Against
Study of the Bioaccumulation of Tinzaparin in Renally Impaired Patients When Given at Prophylactic Doses
The purpose of this study is to assess if accumulation of anti-Xa activity occurs after repeated daily administration of prophylactic doses of tinzaparin in patients with severe chronic kidney disease (CKD) requiring…
- Trial name
- STRIP (NCT02719418)
- Testing
- Tinzaparin
- Where
- Canada
- Volunteers
- 28 people
- Sponsor
- Maisonneuve-Rosemont Hospital
Thromboembolism, Hemodialysis
A Comparison of Dalteparin and Tinzaparin for Prevention of Blood Clots in Hemodialysis Patients on Oral Anticoagulants Having Surgery
The purpose of this study is to better understand if either dalteparin or tinzaparin is a better drug to use in dialysis patients on blood thinners who are at high risk of developing blood clots and need surgery.
- Trial name
- NCT00260988
- Testing
- Fragmin (dalteparin), Innohep (tinzaparin)
- Where
- 2 sites in Canada
- Volunteers
- 29 people
- Sponsor
- Ottawa Hospital Research Institute
Pulmonary Embolism, Deep Vein Thrombosis
Angel® Catheter Early Feasibility Clinical Study
The primary objective of this clinical trial is to obtain initial insights into the safety of the Angel® Catheter in critically ill subjects with high risk of venous thromboembolism (VTE) disease AND who are not receiving…
- Conditions
- Pulmonary Embolism, Deep Vein Thrombosis, Venous Thromboembolism
- Trial name
- NCT01847196
- Testing
- Angel® Catheter
- Where
- 4 sites in United States
- Volunteers
- 6 people
- Sponsor
- BiO2 Medical
Thromboembolism
Phase III Study Testing Efficacy & Safety of Oral Dabigatran Etexilate vs Warfarin for 6 m Treatment for Acute Symp Venous Thromboembolism (VTE)
The general aim of this study is to determine the comparative safety and efficacy of dabigatran etexilate 150 mg bid administered orally and warfarin Pro re nata (As needed/PRN) to maintain an International Normalised Ratio (INR)…
- Trial name
- RE-COVER II (NCT00680186)
- Testing
- Warfarin, Dabigatran etexilate
- Where
- 220 sites in United States, Australia and 29 more
- Volunteers
- 2,589 people
- Sponsor
- Boehringer Ingelheim
Dose Adjustment of Enoxaparin in ICU Patients
Anti-factor Xa Based Venous Thromboembolism Prophylaxis
Introduction: Venous thromboembolism (VTE) in the intensive care unit (ICU) is associated with significant morbidity and mortality therefore prevention is imperative to reduce its burden.
- Trial name
- NCT05221879
- Testing
- Dose adjustment of Enoxaparin in patients with sub-therapuetic (prophylactic) levels of factor 10a
- Where
- Israel
- Volunteers
- 75 people
- Sponsor
- Meir Medical Center
Venous Thromboses, Venous Thromboembolism
The Risk of Venous Thromboembolism in Systemic Inflammatory Disorders: a United Kingdom (UK) Matched Cohort Study
Blood clots occurring in the legs and in the lungs are relatively common; they occur in around 3 in a 1000 people per year. They can cause disability and are also potentially life threatening.
- Conditions
- Venous Thromboses, Venous Thromboembolism, Deep Vein Thrombosis, Pulmonary Embolism
- Trial name
- NCT03835780
- Testing
- No intervention
- Where
- United Kingdom
- Volunteers
- 266,890 people, healthy volunteers welcome
- Sponsor
- Momentum Data
Venous Thromboembolism
Study of Venous Thromboembolism Risk Profiles and Prophylaxis in Neurosurgical Inpatients
Venous thromboembolism (VTE), comprising deep venous thrombosis (DVT), pulmonary embolism (PE), or both, is a life-threatening complication in postoperative patients.
- Trial name
- VTE (NCT04257305)
- Where
- China
- Volunteers
- 9,010 people
- Sponsor
- Huashan Hospital
Atrial Fibrillation, Assessment of Serious Advers Events
Prospective Registration and Assessment of Serious Adverse Events Within the AFNET
Prospective registration and independent assessment of SAE associated with atrial fibrillation such as thromboembolic events, and other cardiac and noncardiac complications by a Critical Event Committee.
- Conditions
- Atrial Fibrillation, Assessment of Serious Advers Events, Thromboembolic and Bleeding Complications, Complications of Antiarrhythmic Drugs or Invasive Procedures
- Trial name
- AFNET A7 (NCT01678456)
- Where
- Germany
- Volunteers
- 13,000 people
- Sponsor
- Atrial Fibrillation Network
Thromboembolism
Hip Fracture Study of GSK576428 (Fondaparinux Sodium)
This study is requested by PMDA to confirm the efficacy and the safety for HFS.
- Trial name
- NCT00320424
- Testing
- Fondaparinux
- Volunteers
- 48 people
- Sponsor
- GlaxoSmithKline
Venous Thromboembolism, Deep Vein Thrombosis
Venous Thrombo-Embolism Imaging Database (VTE-ID)
The purpose of this study is to identify and validate new imaging biomarkers allowing an individual phenotyping of patient with venous thrombo-embolism (VTE), mainly in terms of recurrence risk assessment and to distinguish…
- Conditions
- Venous Thromboembolism, Deep Vein Thrombosis, Pulmonary Embolism
- Trial name
- VTE-ID (NCT06258694)
- Where
- France
- Volunteers
- 2,208 people
- Sponsor
- University Hospital, Brest
Venous Thromboembolism, Anticoagulants and Bleeding Disorders
Anticoagulation Length of ThErapy and Risk of New Adverse evenTs In Venous thromboEmbolism Study
The proposed research seeks to provide insights on the contemporary epidemiology, treatment, and outcomes of VTE, including examining the uptake of new treatment strategies, the efficacy and safety of different anticoagulant…
- Trial name
- ALTERNATIVE (NCT03292666)
- Testing
- Oral Anticoagulant
- Where
- 2 sites in United States
- Volunteers
- 39,603 people
- Sponsor
- University of California, San Francisco
Trauma, Venous Thromboembolism
Feasibility Study of Geko vs. IPCs in Trauma
Trauma patients are at a high risk of developing blood clots in the legs (deep vein thrombosis - DVT), which can travel to the lungs and cause serious health consequences.
- Trial name
- GIFT Pilot (NCT01835990)
- Testing
- geko, IPCs
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Hamilton Health Sciences Corporation
Carotid Atherosclerosis, Carotid Stenosis
Carotid Arteries Stenting Complications: Transradial Approach Versus Transfemoral
The aim is to compare the safety of using transfemoral and transradial approach in patient undergoing carotid arteries stenting.
- Conditions
- Carotid Atherosclerosis, Carotid Stenosis, Ischemic Attack, Stroke
- Trial name
- NCT02722720
- Testing
- Transradial carotid artery stenting, Transfemoral carotid artery stenting
- Where
- Russia
- Volunteers
- 200 people
- Sponsor
- Meshalkin Research Institute of Pathology of Circulation
Venous Thromboembolism, Clinical Decision Support Systems
Smart Technology Facilitated Venous Thromboembolism Prophylaxis Based on Bundled Evidence-based Prevention Strategies
Venous thromboembolism (VTE) is the third leading cause of cardiovascular disease deaths globally, and its incidence is increasing over the years.
- Conditions
- Venous Thromboembolism, Clinical Decision Support Systems, Digital Health
- Trial name
- SmaVTE-BEST (NCT06353373)
- Testing
- Application of the modified DeVTEcare system
- Volunteers
- 15,626 people
- Sponsor
- Navy General Hospital, Beijing
Anticoagulants, Atrial Fibrillation
Improving Anticoagulation Control in VISN 1
Over 100,000 VHA patients receive anticoagulants (blood thinners) each year to prevent blood clots (including strokes). Too much anticoagulation increases the risk of serious or even fatal bleeding, and too little anticoagulation…
- Conditions
- Anticoagulants, Atrial Fibrillation, Venous Thromboembolism
- Trial name
- NCT01653405
- Testing
- Multifaceted behavioral intervention
- Where
- United States
- Volunteers
- 1,260,576 people
- Sponsor
- VA Office of Research and Development
Venous Thromboembolism
Replication of the RECOVER-II Anticoagulant Trial in Healthcare Claims Data
Investigators are building an empirical evidence base for real world data through large-scale replication of randomized controlled trials.
- Trial name
- NCT04735523
- Testing
- Dabigatran, Warfarin
- Where
- United States
- Volunteers
- 5,350 people
- Sponsor
- Brigham and Women's Hospital
Venous Thromboembolic Disease, Pulmonary Embolism
CHIPs-VTE Study in Hospitalized Patients With Lung Cancer
Venous thromboembolism (VTE) is a common complication of malignancies, in particular to lung cancer. Patients with lung cancer in surgical and medical departments are at high risk of VTE development.
- Conditions
- Venous Thromboembolic Disease, Pulmonary Embolism, Deep Venous Thrombosis
- Trial name
- NCT04158973
- Testing
- Bleeding-risk based prophylaxis strategy during hospitalization and extended pharmacological treatment after discharge, Routine VTE prophylaxis in hospital
- Volunteers
- 3,200 people
- Sponsor
- China-Japan Friendship Hospital
Atherosclerotic Vascular Disease, Coronary Arterial Disease (CAD)
Genetic Testing of CYP2C19 in Prognostic Evaluation of Long-Term Major Adverse Cardiac and Vascular Events
Several studies have shown that the efficacy of clopidogrel for secondary prevention of major adverse cardiovascular events (MACE), including acute coronary syndrome, depends on the polymorphism of the CYP2C19 gene.
- Conditions
- Atherosclerotic Vascular Disease, Coronary Arterial Disease (CAD), Atherosclerosis of Coronary Artery, Atherosclerosis of Arteries of the Extremities, Unspecified
- Trial name
- UF-GENOTYPE (NCT06855394)
- Where
- 2 sites in United States
- Volunteers
- 13,000 people
- Sponsor
- University of Florida
Aortic Dissection, Thrombosis in Left Atrium and Right Axillary Artery
Multi-detector Computer Tomography Protocol Project: Chest Imaging Technique and Case Presentation
Multi-detector computer tomography protocol project: Chest imaging technique and case presentation.
- Conditions
- Aortic Dissection, Thrombosis in Left Atrium and Right Axillary Artery, Double IVC, May-Thurner Syndrome
- Trial name
- NCT01206751
- Testing
- Chest imaging technique and case presentation
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Taipei Medical University WanFang Hospital
Venous Thromboembolism
Dose-confirmatory Bridging Study in Total Knee Replacement
The objective of this dose-confirmatory bridging study is to investigate the safety and efficacy of rivaroxaban 5 to 10 mg once-daily (od) dosing in the prevention of venous thromboembolism (VTE) in Japanese patients undergoing…
- Trial name
- NCT01206972
- Testing
- Rivaroxaban (BAY59-7939), Enoxaparin
- Where
- 33 sites in Japan
- Volunteers
- 302 people
- Sponsor
- Bayer
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.